Analysis of disease-associated ND4 mutations: How do we know which mutation is pathogenic?

Mitochondrion

Volumn 7, Issue 1-2, 2007, Pages 151-156

  Tzen, Chin Yuan ^a,b,c,d   Mau, Bey Liing ^e   Hsu, Hsiu Jun ^a  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b NURSING AND MANAGEMENT COLLEGE   (Taiwan)

^c NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e Sun Yat Sen Cancer Center   (Taiwan)

Author keywords

Conservation index; Evolutional analysis; Mitochondrial mutation; mtDNA; NADH dehydrogenase subunit 4 (ND4)

Indexed keywords

MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ARTICLE; BREAST CANCER; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; ESOPHAGUS CANCER; GENE MUTATION; GENETIC ASSOCIATION; GENETIC CONSERVATION; HEAD AND NECK CANCER; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; LEIGH DISEASE; LIVER CANCER; MAJOR CLINICAL STUDY; MAMMAL; MEDULLOBLASTOMA; MELAS SYNDROME; MOUTH CANCER; NONHUMAN; PANCREAS CANCER; PARATHYROID ADENOMA; PATHOGENICITY; PRIMATE; PRIORITY JOURNAL; TACHYCARDIA; THYROID CARCINOMA; TRANSITIONAL CELL CARCINOMA;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; DNA, MITOCHONDRIAL; EVOLUTION, MOLECULAR; HUMANS; MITOCHONDRIAL DISEASES; NADH DEHYDROGENASE;

MAMMALIA; PRIMATES;

EID: 33847691157     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2006.11.007     Document Type: Article

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