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Volumn 82, Issue 3, 2007, Pages 349-353

Breast cancer in patients carrying a germ-line CHEK2 mutation: Outcome after breast conserving surgery and adjuvant radiotherapy

Author keywords

ATM; Breast cancer; CHEK2 germline mutation; Metastasis free survival

Indexed keywords

CHECKPOINT KINASE 2; CYCLOPHOSPHAMIDE; EPIRUBICIN; FLUOROURACIL; METHOTREXATE; TAMOXIFEN;

EID: 33847670113     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2006.12.002     Document Type: Article
Times cited : (27)

References (29)
  • 1
    • 3242884449 scopus 로고    scopus 로고
    • The Chk2 protein kinase
    • Ahn J., Urist M., and Prives C. The Chk2 protein kinase. DNA Repair 3 (2004) 1039-1047
    • (2004) DNA Repair , vol.3 , pp. 1039-1047
    • Ahn, J.1    Urist, M.2    Prives, C.3
  • 2
    • 0037033733 scopus 로고    scopus 로고
    • A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes
    • Antoniou A.C., Pharoah P.D., McMullan G., et al. A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes. Br J Cancer 86 (2002) 76-83
    • (2002) Br J Cancer , vol.86 , pp. 76-83
    • Antoniou, A.C.1    Pharoah, P.D.2    McMullan, G.3
  • 4
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • Bartek J., and Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3 (2003) 421-429
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 5
    • 22044445244 scopus 로고    scopus 로고
    • Association of two mutations in the CHEK2 gene with breast cancer
    • Bogdanova N., Enssen-Dubrowinskaja N., Feshchenko S., et al. Association of two mutations in the CHEK2 gene with breast cancer. Int J Cancer 116 (2005) 263-266
    • (2005) Int J Cancer , vol.116 , pp. 263-266
    • Bogdanova, N.1    Enssen-Dubrowinskaja, N.2    Feshchenko, S.3
  • 6
    • 0942279575 scopus 로고    scopus 로고
    • Excess risk for contralateral breast cancer in CHEK2*1100delC germline mutation carriers
    • Broeks A., de Witte L., Nooijen A., et al. Excess risk for contralateral breast cancer in CHEK2*1100delC germline mutation carriers. Breast Cancer Res Treat 83 (2004) 91-93
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 91-93
    • Broeks, A.1    de Witte, L.2    Nooijen, A.3
  • 7
    • 12144286870 scopus 로고    scopus 로고
    • Ser49Cys variant in the ataxia telangiectasia, mutated, gene that is more common in patients with breast carcinoma compared with population controls
    • Buchholz T.A., Weil M.M., Ashorn C.L., et al. Ser49Cys variant in the ataxia telangiectasia, mutated, gene that is more common in patients with breast carcinoma compared with population controls. Cancer 100 (2004) 1345-1351
    • (2004) Cancer , vol.100 , pp. 1345-1351
    • Buchholz, T.A.1    Weil, M.M.2    Ashorn, C.L.3
  • 8
    • 3042582651 scopus 로고    scopus 로고
    • CHEK2 Breast Cancer Case-Control Consortium. CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. Am J Hum Genet 2004;74:1175-821.
  • 9
    • 8844220451 scopus 로고    scopus 로고
    • CHEK2 is a multiorgan cancer susceptibility gene
    • Cybulski C., Gorski B., Huzarski T., et al. CHEK2 is a multiorgan cancer susceptibility gene. Am J Hum Genet 75 (2004) 1131-1135
    • (2004) Am J Hum Genet , vol.75 , pp. 1131-1135
    • Cybulski, C.1    Gorski, B.2    Huzarski, T.3
  • 10
    • 6344261987 scopus 로고    scopus 로고
    • Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2*1100delC variant
    • de Bock G.H., Schutte M., Krol-Warmerdam E.M., et al. Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2*1100delC variant. J Med Genet 41 (2004) 731-735
    • (2004) J Med Genet , vol.41 , pp. 731-735
    • de Bock, G.H.1    Schutte, M.2    Krol-Warmerdam, E.M.3
  • 11
    • 0035887491 scopus 로고    scopus 로고
    • Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients
    • Dörk T., Bendix R., Bremer M., et al. Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients. Cancer Res 61 (2001) 7608-7615
    • (2001) Cancer Res , vol.61 , pp. 7608-7615
    • Dörk, T.1    Bendix, R.2    Bremer, M.3
  • 12
    • 0035848819 scopus 로고    scopus 로고
    • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
    • Falck J., Mailand N., Syljuasen R.G., Bartek J., and Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410 (2001) 842-847
    • (2001) Nature , vol.410 , pp. 842-847
    • Falck, J.1    Mailand, N.2    Syljuasen, R.G.3    Bartek, J.4    Lukas, J.5
  • 14
    • 0034707106 scopus 로고    scopus 로고
    • Roads leading to breast cancer
    • Haber D. Roads leading to breast cancer. N Engl J Med 343 (2000) 1566-1568
    • (2000) N Engl J Med , vol.343 , pp. 1566-1568
    • Haber, D.1
  • 15
    • 17644368911 scopus 로고    scopus 로고
    • Pathology of breast cancer in women with constitutional CHEK2 mutations
    • Huzarski T., Cybulski C., Domagala W., et al. Pathology of breast cancer in women with constitutional CHEK2 mutations. Breast Cancer Res Treat 90 (2005) 187-189
    • (2005) Breast Cancer Res Treat , vol.90 , pp. 187-189
    • Huzarski, T.1    Cybulski, C.2    Domagala, W.3
  • 16
    • 27544515629 scopus 로고    scopus 로고
    • Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: a familial study
    • Johnson N., Fletcher O., Naceur-Lombardelli C., dos Santos Silva I., Ashworth A., and Peto J. Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: a familial study. Lancet 366 (2005) 1554-1557
    • (2005) Lancet , vol.366 , pp. 1554-1557
    • Johnson, N.1    Fletcher, O.2    Naceur-Lombardelli, C.3    dos Santos Silva, I.4    Ashworth, A.5    Peto, J.6
  • 17
    • 19944424422 scopus 로고    scopus 로고
    • Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients
    • Kilpivaara O., Bartkova J., Eerola H., et al. Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients. Int J Cancer 113 (2005) 575-580
    • (2005) Int J Cancer , vol.113 , pp. 575-580
    • Kilpivaara, O.1    Bartkova, J.2    Eerola, H.3
  • 18
    • 3843071233 scopus 로고    scopus 로고
    • CHEK2 variant I157T may be associated with increased breast cancer risk
    • Kilpivaara O., Vahteristo P., Falck J., et al. CHEK2 variant I157T may be associated with increased breast cancer risk. Int J Cancer 111 (2004) 543-547
    • (2004) Int J Cancer , vol.111 , pp. 543-547
    • Kilpivaara, O.1    Vahteristo, P.2    Falck, J.3
  • 20
    • 18544389716 scopus 로고    scopus 로고
    • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations
    • Meijers-Heijboer H., van den Ouweland A., Klijn J., et al. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 31 (2002) 55-59
    • (2002) Nat Genet , vol.31 , pp. 55-59
    • Meijers-Heijboer, H.1    van den Ouweland, A.2    Klijn, J.3
  • 21
    • 4644258760 scopus 로고    scopus 로고
    • Breast cancer in female carriers of ATM gene alterations: outcome of adjuvant radiotherapy
    • Meyer A., John E., Dörk T., Sohn C., Karstens J.H., and Bremer M. Breast cancer in female carriers of ATM gene alterations: outcome of adjuvant radiotherapy. Radiother Oncol 72 (2004) 319-323
    • (2004) Radiother Oncol , vol.72 , pp. 319-323
    • Meyer, A.1    John, E.2    Dörk, T.3    Sohn, C.4    Karstens, J.H.5    Bremer, M.6
  • 24
    • 14044272193 scopus 로고    scopus 로고
    • Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population
    • Shaag A., Walsh T., Renbaum P., et al. Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population. Hum Mol Genet 14 (2005) 555-563
    • (2005) Hum Mol Genet , vol.14 , pp. 555-563
    • Shaag, A.1    Walsh, T.2    Renbaum, P.3
  • 25
    • 0034142034 scopus 로고    scopus 로고
    • The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
    • Shieh S.Y., Ahn J., Tamai K., Taya Y., and Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev 14 (2000) 289-300
    • (2000) Genes Dev , vol.14 , pp. 289-300
    • Shieh, S.Y.1    Ahn, J.2    Tamai, K.3    Taya, Y.4    Prives, C.5
  • 26
    • 0035425350 scopus 로고    scopus 로고
    • Increased frequency of ATM mutations in breast carcinoma patients with early onset disease and positive family history
    • Teraoka S.N., Malone K.E., Doody D.R., et al. Increased frequency of ATM mutations in breast carcinoma patients with early onset disease and positive family history. Cancer 92 (2001) 479-487
    • (2001) Cancer , vol.92 , pp. 479-487
    • Teraoka, S.N.1    Malone, K.E.2    Doody, D.R.3
  • 27
    • 18444379055 scopus 로고    scopus 로고
    • A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer
    • Vahteristo P., Bartkova J., Eerola H., et al. A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer. Am J Hum Genet 71 (2002) 432-438
    • (2002) Am J Hum Genet , vol.71 , pp. 432-438
    • Vahteristo, P.1    Bartkova, J.2    Eerola, H.3
  • 28
    • 0038415852 scopus 로고    scopus 로고
    • A growing network of cancer susceptibility genes
    • Venkitaraman A.R. A growing network of cancer susceptibility genes. N Engl J Med 348 (2003) 1917-1919
    • (2003) N Engl J Med , vol.348 , pp. 1917-1919
    • Venkitaraman, A.R.1
  • 29
    • 33645084562 scopus 로고    scopus 로고
    • Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer
    • Walsh T., Casadei S., Coats K.H., et al. Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. JAMA 295 (2006) 1379-1388
    • (2006) JAMA , vol.295 , pp. 1379-1388
    • Walsh, T.1    Casadei, S.2    Coats, K.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.