Roads leading to breast cancer

New England Journal of Medicine

Volumn 343, Issue 21, 2000, Pages 1566-1568

  Haber, D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN MDM2;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; CANCER SUSCEPTIBILITY; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA STRAND BREAKAGE; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; MEDICAL GENETICS; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; TUMOR SUPPRESSOR GENE;

BRCA2 PROTEIN; BREAST NEOPLASMS; GENES, BRCA1; GERM-LINE MUTATION; HUMANS; NEOPLASM PROTEINS; TRANSCRIPTION FACTORS;

EID: 0034707106     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200011233432111     Document Type: Article

References (10)

1. Requirement of ATM-dependent phosphorylation of brcal in the DNA damage response to double-strand breaks
2. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
3. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
4. DNA damage-induced activation of p53 by the checkpoint kinase Chk2
5. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
6. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
7. hCdsl-Mediated phosphorylation of BRCA1 regulates the DNA damage response
8. BASC, a super complex of BRCAl-associated proteins involved in the recognition and repair of aberrant DNA structures
9. Incidence of cancer in 161 families affected by ataxia-telangiectasia
10. Heterozygous ATM mutations do not contribute to early onset of breast cancer