Identifying glucagon-like peptide-1 mimetics using a novel functional reporter gene high-throughput screening assay

Peptides

Volumn 28, Issue 4, 2007, Pages 928-934

  Chen, Jiaqi ^a   Bai, Gang ^a   Yang, Yang ^a   Geng, Peng ^a   Cao, Yu ^a   Zhu, Yuanyuan ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

GLP 1; High throughput screening; Mimetic peptides; Phage display peptide library; Reporter gene

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; CYCLIC AMP; DIPEPTIDYL PEPTIDASE IV; ENHANCED GREEN FLUORESCENT PROTEIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE; LYSYLHISTIDYLALANYLASPARTYLGLYCYLSERYLPHENYLALANYLISOLEUCYL THREONYLGLUTAMYLALANYLSERINE; PEPTIDE LIBRARY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHO CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; HIGH THROUGHPUT SCREENING; MOLECULAR CLONING; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; REPORTER GENE; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; BLOOD GLUCOSE; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE TOLERANCE TEST; GREEN FLUORESCENT PROTEINS; HYPOGLYCEMIC AGENTS; INJECTIONS, INTRAPERITONEAL; MICE; PEPTIDE LIBRARY; PEPTIDES; RATS; RECEPTORS, GLUCAGON; TRANSFECTION;

MUS; RATTUS;

EID: 33847412371     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.12.012     Document Type: Article

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