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Volumn 17, Issue 1, 2007, Pages 3-9

Cyclodextrins in ocular drug delivery: Theoretical basis with dexamethasone as a sample drug

Author keywords

Aqueous solution; Availability; Cyclodextrin; Dexamethasone; Eye drops; Ophthalmic; Permeation; Topical drug delivery

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ACETAZOLAMIDE; ALPHA CYCLODEXTRIN; ANANDAMIDE; BETA CYCLODEXTRIN; CANNABINOID DERIVATIVE; CHLORAMPHENICOL; CLOROCIL; CYCLODEXTRIN DERIVATIVE; CYCLOSPORIN; DEXAMETHASONE; DICLOFENAC; DIPIVEFRINE; DISULFIRAM; DORZOLAMIDE; EYE DROPS; FLUOROMETHOLONE; GAMMA CYCLODEXTRIN; GANCICLOVIR DERIVATIVE; HYDROCORTISONE; LOTEPREDNOL ETABONATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PILOCARPINE; PRASTERONE; PROSTAGLANDIN DERIVATIVE; RUFLOXACIN; THALIDOMIDE; TROPICAMIDE; UNCLASSIFIED DRUG;

EID: 33847411896     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(07)50001-8     Document Type: Review
Times cited : (52)

References (86)
  • 1
    • 0023553501 scopus 로고
    • Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea
    • Ahmed I., Gokhale R.D., Shah M.V., Patton T.F. - Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea. - J. Pharm. Sci., 76, 583-586, 1987.
    • (1987) J. Pharm. Sci , vol.76 , pp. 583-586
    • Ahmed, I.1    Gokhale, R.D.2    Shah, M.V.3    Patton, T.F.4
  • 2
    • 0025775370 scopus 로고
    • Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: A comparison with corneal penetration
    • Wang W., Sasaki H., Chien D.-S., Lee V.H.L. - Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration. - Curr. Eye Res., 10, 571-579, 1991.
    • (1991) Curr. Eye Res , vol.10 , pp. 571-579
    • Wang, W.1    Sasaki, H.2    Chien, D.-S.3    Lee, V.H.L.4
  • 3
    • 0343907824 scopus 로고    scopus 로고
    • Effect of cyclodextrins on topical drug delivery to the eye
    • Loftsson T., Stefánsson E. - Effect of cyclodextrins on topical drug delivery to the eye. - Drug Devel. Ind. Pharm., 23, 473-481, 1997.
    • (1997) Drug Devel. Ind. Pharm , vol.23 , pp. 473-481
    • Loftsson, T.1    Stefánsson, E.2
  • 4
    • 0015850330 scopus 로고
    • Lacrimal and instilled fluid dynamics in rabbit eye
    • Chrai S.S., Patton T.F., Mehta A., Robinson J.R. - Lacrimal and instilled fluid dynamics in rabbit eye. - J. Pharm. Sci., 62, 1112-1121, 1973.
    • (1973) J. Pharm. Sci , vol.62 , pp. 1112-1121
    • Chrai, S.S.1    Patton, T.F.2    Mehta, A.3    Robinson, J.R.4
  • 5
    • 0027252620 scopus 로고
    • Minimizing systemic absorption of topically administered ophthalmic drugs
    • Urtti A., Salminen L. - Minimizing systemic absorption of topically administered ophthalmic drugs. - Surv. Ophthalmol., 37, 435-456, 1993.
    • (1993) Surv. Ophthalmol , vol.37 , pp. 435-456
    • Urtti, A.1    Salminen, L.2
  • 6
    • 0344286485 scopus 로고    scopus 로고
    • Cyclodextrins in ophthalmic drug delivery
    • Loftsson T., Järvinen T. - Cyclodextrins in ophthalmic drug delivery. - Adv. Drug Deliv. Rev., 36, 59-79, 1999.
    • (1999) Adv. Drug Deliv. Rev , vol.36 , pp. 59-79
    • Loftsson, T.1    Järvinen, T.2
  • 7
    • 0003527066 scopus 로고
    • Cyclodextrins and their Industrial Uses
    • Duchêne D, Ed, Paris
    • Duchêne D. (Ed.) - Cyclodextrins and their Industrial Uses. - Editions de Santé, Paris, 1987.
    • (1987) Editions de Santé
  • 9
    • 85030514856 scopus 로고
    • New Trends in Cyclodextrins and Derivatives
    • Duchêne D, Ed, Paris
    • Duchêne D. (Ed.) - New Trends in Cyclodextrins and Derivatives. - Editions de Santé, Paris, 1991.
    • (1991) Editions de Santé
  • 11
    • 0029819323 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. 1.Drug solubilization and stabilization
    • Loftsson T., Brewster M.E. - Pharmaceutical applications of cyclodextrins. 1.Drug solubilization and stabilization. - J. Pharm. Sci., 85, 1017-1025, 1996.
    • (1996) J. Pharm. Sci , vol.85 , pp. 1017-1025
    • Loftsson, T.1    Brewster, M.E.2
  • 12
    • 0029852699 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. 2. In vivo drug delivery
    • Rajewski R.A., Stella V.J. - Pharmaceutical applications of cyclodextrins. 2. In vivo drug delivery. - J. Pharm. Sci., 85, 1142-1168, 1996.
    • (1996) J. Pharm. Sci , vol.85 , pp. 1142-1168
    • Rajewski, R.A.1    Stella, V.J.2
  • 13
    • 0031054513 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation
    • Irie T., Uekama K. - Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation. - J. Pharm. Sci., 86, 147-162, 1997.
    • (1997) J. Pharm. Sci , vol.86 , pp. 147-162
    • Irie, T.1    Uekama, K.2
  • 14
    • 8244248457 scopus 로고    scopus 로고
    • Cyclodextrins: Their future in drug formulation and delivery
    • Stella V. J., Rajewski R. A. - Cyclodextrins: their future in drug formulation and delivery. - Pharm. Res., 14, 556-567, 1997.
    • (1997) Pharm. Res , vol.14 , pp. 556-567
    • Stella, V.J.1    Rajewski, R.A.2
  • 15
    • 0031042310 scopus 로고    scopus 로고
    • Cyclodextrins-enabling excipients: Their present and future use in pharmaceuticals
    • Thompson D.O. - Cyclodextrins-enabling excipients: their present and future use in pharmaceuticals. - Crit. Rev. Ther. Drug Carrier Syst., 14, 1-104, 1997.
    • (1997) Crit. Rev. Ther. Drug Carrier Syst , vol.14 , pp. 1-104
    • Thompson, D.O.1
  • 18
    • 0036117863 scopus 로고    scopus 로고
    • Cyclodextrins in eye drop formulations: Enhanced topical delivery of corticosteroids to the eye
    • Loftsson T., Stefánsson E. - Cyclodextrins in eye drop formulations: enhanced topical delivery of corticosteroids to the eye. - Acta Ophthalmol. Scand., 80, 144-150, 2002.
    • (2002) Acta Ophthalmol. Scand , vol.80 , pp. 144-150
    • Loftsson, T.1    Stefánsson, E.2
  • 19
    • 33645768791 scopus 로고    scopus 로고
    • Kaur I.P., Chhabra S., Aggarwal D. - Role of cyclodextrins in ophthalmics. - Curr. Drug Deliv., 1, 351-360, 2004.
    • Kaur I.P., Chhabra S., Aggarwal D. - Role of cyclodextrins in ophthalmics. - Curr. Drug Deliv., 1, 351-360, 2004.
  • 20
    • 11044221846 scopus 로고    scopus 로고
    • Role of cyclodextrins in improving oral drug delivery
    • Loftsson T., Brewster M.E., Másson M. - Role of cyclodextrins in improving oral drug delivery. - Am. J. Drug Deliv., 2, 261-275, 2004.
    • (2004) Am. J. Drug Deliv , vol.2 , pp. 261-275
    • Loftsson, T.1    Brewster, M.E.2    Másson, M.3
  • 21
    • 1942470488 scopus 로고    scopus 로고
    • Cyclodextrins and their uses: A review
    • Del Valle E.M.M. - Cyclodextrins and their uses: a review. - Process Biochem., 39, 1033-1046, 2004.
    • (2004) Process Biochem , vol.39 , pp. 1033-1046
    • Del Valle, E.M.M.1
  • 23
    • 1842451466 scopus 로고    scopus 로고
    • The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugs.
    • Loftsson T., Másson M. - The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugs. - J. Drug Del. Sci. Tech., 14, 35-43, 2004.
    • (2004) J. Drug Del. Sci. Tech , vol.14 , pp. 35-43
    • Loftsson, T.1    Másson, M.2
  • 24
    • 1942434694 scopus 로고    scopus 로고
    • Self-association of cyclodextrins and cyclodextrin complexes
    • Loftsson T., Másson M., Brewster M. E. - Self-association of cyclodextrins and cyclodextrin complexes. - J. Pharm. Sci., 93, 1091-1099, 2004.
    • (2004) J. Pharm. Sci , vol.93 , pp. 1091-1099
    • Loftsson, T.1    Másson, M.2    Brewster, M.E.3
  • 25
    • 0022592084 scopus 로고
    • Hydroxypropyl-β-cyclodextrin: Preparation and characterization; effects on solubility of drugs
    • Pitha J., Milecki J., Fales H., Pannell L., Uekama K. - Hydroxypropyl-β-cyclodextrin: preparation and characterization; effects on solubility of drugs. - Int. J. Pharm., 29, 73-82, 1986.
    • (1986) Int. J. Pharm , vol.29 , pp. 73-82
    • Pitha, J.1    Milecki, J.2    Fales, H.3    Pannell, L.4    Uekama, K.5
  • 26
    • 0043135058 scopus 로고    scopus 로고
    • The effects of organic salts on the cyclodextrin solubilization of drugs
    • Loftsson T., Matthíasson K., Másson M. - The effects of organic salts on the cyclodextrin solubilization of drugs. - Int. J. Pharm., 262, 101-107, 2003.
    • (2003) Int. J. Pharm , vol.262 , pp. 101-107
    • Loftsson, T.1    Matthíasson, K.2    Másson, M.3
  • 27
    • 0025736224 scopus 로고
    • 2-hydroxypropyl-β-cyclodextrin: Properties and usage in pharmaceutical formulations
    • Loftsson T., Brewster M. E., Derendorf H., Bodor N. - 2-hydroxypropyl-β-cyclodextrin: properties and usage in pharmaceutical formulations. - Pharm. Ztg. Wiss., 136, 5-10, 1991.
    • (1991) Pharm. Ztg. Wiss , vol.136 , pp. 5-10
    • Loftsson, T.1    Brewster, M.E.2    Derendorf, H.3    Bodor, N.4
  • 28
    • 33644555897 scopus 로고    scopus 로고
    • Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes
    • Loftsson T., Konrádsdóttir F., Másson M. - Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes. - Pharmazie, 61, 83-89, 2006.
    • (2006) Pharmazie , vol.61 , pp. 83-89
    • Loftsson, T.1    Konrádsdóttir, F.2    Másson, M.3
  • 29
    • 0015295910 scopus 로고
    • Total mathematical resolution of diffusion layer control of barrier flux
    • Flynn G.L., Carpender O.S., Yalkowsky S.H. - Total mathematical resolution of diffusion layer control of barrier flux. - J. Pharm. Sci., 61, 312-314, 1972.
    • (1972) J. Pharm. Sci , vol.61 , pp. 312-314
    • Flynn, G.L.1    Carpender, O.S.2    Yalkowsky, S.H.3
  • 30
    • 0035964466 scopus 로고    scopus 로고
    • Cyclodextrins in topical drug formulations: Theory and practice
    • Loftsson T., Masson M. - Cyclodextrins in topical drug formulations: theory and practice. - Int. J. Pharm., 225, 15-30, 2001.
    • (2001) Int. J. Pharm , vol.225 , pp. 15-30
    • Loftsson, T.1    Masson, M.2
  • 31
    • 0141701162 scopus 로고    scopus 로고
    • Cyclodextrins as permeation enhancers: Some theoretical evaluations and in vitro testing
    • Masson M., Loftsson T., Masson G., Stefansson E. - Cyclodextrins as permeation enhancers: some theoretical evaluations and in vitro testing. - J. Control. Rel., 59, 107-118, 1999.
    • (1999) J. Control. Rel , vol.59 , pp. 107-118
    • Masson, M.1    Loftsson, T.2    Masson, G.3    Stefansson, E.4
  • 33
    • 85030510470 scopus 로고    scopus 로고
    • Personal communication: octanol/water partition coefficients of cyclodextrins, Wacker-Chemie GmbH, Burghausen, 2004
    • Moldenhauer J. - Personal communication: octanol/water partition coefficients of cyclodextrins. - Wacker-Chemie GmbH, Burghausen, 2004.
    • Moldenhauer, J.1
  • 34
    • 0028948839 scopus 로고
    • A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
    • Amidon G.L., Lennernäs H., Shah V.P., Crison J.R. - A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. - Pharm. Res., 12, 413-420, 1995.
    • (1995) Pharm. Res , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernäs, H.2    Shah, V.P.3    Crison, J.R.4
  • 35
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computatorial approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski C.A., Lombardo F., Dominy B.W., Feeney P.J. - Experimental and computatorial approaches to estimate solubility and permeability in drug discovery and development settings. - Adv. Drug Deliv. Rev., 46, 3-26, 2001.
    • (2001) Adv. Drug Deliv. Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 36
    • 0041319200 scopus 로고    scopus 로고
    • Cyclodextrin as skin-penetration enhancers
    • Sinha V.R., Bindra S., Kumria R., Nanda A. - Cyclodextrin as skin-penetration enhancers. - Pharm. Technol., 27(3), 120-138, 2003.
    • (2003) Pharm. Technol , vol.27 , Issue.3 , pp. 120-138
    • Sinha, V.R.1    Bindra, S.2    Kumria, R.3    Nanda, A.4
  • 37
    • 0037347663 scopus 로고    scopus 로고
    • The effects of cyclodextrins on topical delivery of hydrocortisone: The aqueous diffusion layer
    • Loftsson T., Sigfússon S. D., Sigurosson H.H., Másson M. - The effects of cyclodextrins on topical delivery of hydrocortisone: the aqueous diffusion layer. - STP Pharma Sci., 13, 125-131, 2003.
    • (2003) STP Pharma Sci , vol.13 , pp. 125-131
    • Loftsson, T.1    Sigfússon, S.D.2    Sigurosson, H.H.3    Másson, M.4
  • 39
    • 3242673511 scopus 로고    scopus 로고
    • Cyclodextrins in nasal delivery of low-molecular-weight heparins: In vivo and in vitro studies
    • Yang T., Hussain A., Paulson J., Abbruscato T.J., Ahsan F. - Cyclodextrins in nasal delivery of low-molecular-weight heparins: in vivo and in vitro studies. - Pharm. Res., 21, 1127-1136, 2004.
    • (2004) Pharm. Res , vol.21 , pp. 1127-1136
    • Yang, T.1    Hussain, A.2    Paulson, J.3    Abbruscato, T.J.4    Ahsan, F.5
  • 41
    • 24344508654 scopus 로고    scopus 로고
    • Evaluation of cyclodextrin solubilization of drugs
    • Loftsson T., Hreinsdóttir D., Másson M. - Evaluation of cyclodextrin solubilization of drugs. - Int. J. Pharm., 302, 18-28, 2005.
    • (2005) Int. J. Pharm , vol.302 , pp. 18-28
    • Loftsson, T.1    Hreinsdóttir, D.2    Másson, M.3
  • 42
    • 24944504810 scopus 로고    scopus 로고
    • Investigation of drug-cyclodextrin complexes by a phase-distribution method: Some theoretical and practical considerations
    • Másson M., Sigurdardóttir B.V., Matthíasson K., Loftsson T. - Investigation of drug-cyclodextrin complexes by a phase-distribution method: some theoretical and practical considerations. - Chem. Pharm. Bull., 53, 958-964, 2005.
    • (2005) Chem. Pharm. Bull , vol.53 , pp. 958-964
    • Másson, M.1    Sigurdardóttir, B.V.2    Matthíasson, K.3    Loftsson, T.4
  • 43
    • 0028265697 scopus 로고
    • The effect of hydroxypropyl methylcellulose on release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulations
    • Loftsson T., Fridriksdottir H., Thorisdottir S., Stefansson E. - The effect of hydroxypropyl methylcellulose on release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulations. - Int. J. Pharm., 104, 181-184, 1994.
    • (1994) Int. J. Pharm , vol.104 , pp. 181-184
    • Loftsson, T.1    Fridriksdottir, H.2    Thorisdottir, S.3    Stefansson, E.4
  • 44
    • 0031771926 scopus 로고    scopus 로고
    • Efficiency, safety and mechanism of cyclodextrins as absorption enhancers in nasal delivery of peptide and protein drugs
    • Marttin E., Verhoef J.C., Merkus F.W.H.M. - Efficiency, safety and mechanism of cyclodextrins as absorption enhancers in nasal delivery of peptide and protein drugs. - J. Drug Target., 6, 17-36, 1998.
    • (1998) J. Drug Target , vol.6 , pp. 17-36
    • Marttin, E.1    Verhoef, J.C.2    Merkus, F.W.H.M.3
  • 46
    • 33646809319 scopus 로고    scopus 로고
    • Comparison of 0.7% dexamethasone-cyclodextrin with 0.1% dexamethasone sodium phosphate for postoperative inflammation
    • Saari K.M., Nelimarkka L., Ahola V., Loftsson T., Stefánsson E. - Comparison of 0.7% dexamethasone-cyclodextrin with 0.1% dexamethasone sodium phosphate for postoperative inflammation. - Graefe's Arch. Clin. Exp. Ophthalmol., 244, 620-626, 2006.
    • (2006) Graefe's Arch. Clin. Exp. Ophthalmol , vol.244 , pp. 620-626
    • Saari, K.M.1    Nelimarkka, L.2    Ahola, V.3    Loftsson, T.4    Stefánsson, E.5
  • 51
    • 0030604721 scopus 로고    scopus 로고
    • Increase in aqueous solubility, stability and in vitro corneal permeability of anandamide by hydroxypropyl-β-cyclodextrin
    • Jarho P., Urtti A., Pate D.W., Suhonen P., JärvinenT. - Increase in aqueous solubility, stability and in vitro corneal permeability of anandamide by hydroxypropyl-β-cyclodextrin. - Int. J. Pharm., 137, 209-217, 1996.
    • (1996) Int. J. Pharm , vol.137 , pp. 209-217
    • Jarho, P.1    Urtti, A.2    Pate, D.W.3    Suhonen, P.4    JärvinenT5
  • 53
    • 0034961493 scopus 로고    scopus 로고
    • Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on ocular pressure in normotensive rabbits
    • Laine K., Järvinen T., Savinainen J., Laitinen J.T., Pate D.W., Järvinen K. - Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on ocular pressure in normotensive rabbits. - Pharm. Res., 18, 494-499, 2001.
    • (2001) Pharm. Res , vol.18 , pp. 494-499
    • Laine, K.1    Järvinen, T.2    Savinainen, J.3    Laitinen, J.T.4    Pate, D.W.5    Järvinen, K.6
  • 54
    • 0032491366 scopus 로고    scopus 로고
    • Effect of the CB 1 receptor antagonist, SR 141716A, on cannabinoid-induced ocular hypertension in normotensive rabbits
    • Pate D.W., Järvinen K., Urtti A., Mahadevan V., Järvinen T. - Effect of the CB 1 receptor antagonist, SR 141716A, on cannabinoid-induced ocular hypertension in normotensive rabbits. - Life Sci., 63, 2181-2188, 1998.
    • (1998) Life Sci , vol.63 , pp. 2181-2188
    • Pate, D.W.1    Järvinen, K.2    Urtti, A.3    Mahadevan, V.4    Järvinen, T.5
  • 55
    • 0036784933 scopus 로고    scopus 로고
    • Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid
    • Laine K., Järvinen K., Mechoulam R., Breuer A., Järvinen T. - Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid. - Invest. Ophthalmol. Vis. Sci., 43, 3216-3222, 2002.
    • (2002) Invest. Ophthalmol. Vis. Sci , vol.43 , pp. 3216-3222
    • Laine, K.1    Järvinen, K.2    Mechoulam, R.3    Breuer, A.4    Järvinen, T.5
  • 56
    • 0036157052 scopus 로고    scopus 로고
    • Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides
    • Laine K., Järvinen K., Pate D. W., Urtti A., Järvinen T. - Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides. - Invest. Ophthalmol. Vis. Sci., 43, 393-397, 2002.
    • (2002) Invest. Ophthalmol. Vis. Sci , vol.43 , pp. 393-397
    • Laine, K.1    Järvinen, K.2    Pate, D.W.3    Urtti, A.4    Järvinen, T.5
  • 58
    • 0026088403 scopus 로고
    • Topical application of ciclosporin ophthalmic solution containing alpha-cyclodextrin in experimental uveitis
    • Sasamoto Y., Hirose S., Ohno S., Oneé K., Matsuda H. - Topical application of ciclosporin ophthalmic solution containing alpha-cyclodextrin in experimental uveitis. - Ophthalmologica, 203, 118-125, 1991.
    • (1991) Ophthalmologica , vol.203 , pp. 118-125
    • Sasamoto, Y.1    Hirose, S.2    Ohno, S.3    Oneé, K.4    Matsuda, H.5
  • 59
    • 0026663460 scopus 로고
    • Influence of vehicle and anterior chamber protein concentration on cyclosporin penetration through the isolated rabbit cornea
    • Cheeks L., Kaswan R. L., Green K. - Influence of vehicle and anterior chamber protein concentration on cyclosporin penetration through the isolated rabbit cornea. - Curr. Eye Res., 11, 641-649, 1992.
    • (1992) Curr. Eye Res , vol.11 , pp. 641-649
    • Cheeks, L.1    Kaswan, R.L.2    Green, K.3
  • 61
    • 0025930845 scopus 로고
    • Effect of 2-hydroxypropyl-β-cyclodextrin on the ocular absorption of dexamethasone and dexamethasone acetate
    • Usayapant A., Karara A. H., Narurkar M.M. - Effect of 2-hydroxypropyl-β-cyclodextrin on the ocular absorption of dexamethasone and dexamethasone acetate. - Pharm. Res., 12, 1495-1499, 1991.
    • (1991) Pharm. Res , vol.12 , pp. 1495-1499
    • Usayapant, A.1    Karara, A.H.2    Narurkar, M.M.3
  • 62
    • 0000443314 scopus 로고    scopus 로고
    • Dexamethasone eye drops based on the products of its interaction with 2-hydroxypropyl-β-cyclodextrin: Synthesis and study
    • Gavrilin M.V., Kompantseva E.V., Gusova B.A., Ushakova L.S., Makarova V.A., Karpenya L.I. - Dexamethasone eye drops based on the products of its interaction with 2-hydroxypropyl-β-cyclodextrin: synthesis and study. - Pharm. Chem. J., 33, 160-163, 1999.
    • (1999) Pharm. Chem. J , vol.33 , pp. 160-163
    • Gavrilin, M.V.1    Kompantseva, E.V.2    Gusova, B.A.3    Ushakova, L.S.4    Makarova, V.A.5    Karpenya, L.I.6
  • 63
    • 0027931257 scopus 로고
    • In vitro corneal permeability of diclofenac sodium in formulations containing cyclodextrins compared to commercial product Voltaren ophtha
    • Reer O., Bock T.K., Müller B.W. - In vitro corneal permeability of diclofenac sodium in formulations containing cyclodextrins compared to commercial product Voltaren ophtha. - J. Pharm. Sci., 83, 1345-1349, 1994.
    • (1994) J. Pharm. Sci , vol.83 , pp. 1345-1349
    • Reer, O.1    Bock, T.K.2    Müller, B.W.3
  • 64
    • 0030751718 scopus 로고    scopus 로고
    • The use of cyclodextrins in ophthalmic formulations of dipivefrin
    • Jarho P., Järvinen K., Urtti A., Stella V.J., Järvinen T. - The use of cyclodextrins in ophthalmic formulations of dipivefrin. - Int. J. Pharm., 153, 225-233, 1997.
    • (1997) Int. J. Pharm , vol.153 , pp. 225-233
    • Jarho, P.1    Järvinen, K.2    Urtti, A.3    Stella, V.J.4    Järvinen, T.5
  • 65
    • 6344284503 scopus 로고    scopus 로고
    • Bioavailability and anticataract effects of a topical ocular drug delivery system containing disulfiram and hydroxypropyl-beta-cyclodextrin on selenite-treated rats
    • Wang S.L., Di D.X., Ito Y., Nabekura T., Wang S.J., Zhang J.H., Wu C.F. - Bioavailability and anticataract effects of a topical ocular drug delivery system containing disulfiram and hydroxypropyl-beta-cyclodextrin on selenite-treated rats. - Curr. Eye Res., 29, 51-58, 2004.
    • (2004) Curr. Eye Res , vol.29 , pp. 51-58
    • Wang, S.L.1    Di, D.X.2    Ito, Y.3    Nabekura, T.4    Wang, S.J.5    Zhang, J.H.6    Wu, C.F.7
  • 67
    • 23144451233 scopus 로고    scopus 로고
    • Effect of hydroxypropyl beta cyclodextrin complexation on aqueous solubility, stability, and corneal permeation of acyl ester prodrugs of ganciclovir
    • Article
    • Tirucherai G.S., Mitra A.K. - Effect of hydroxypropyl beta cyclodextrin complexation on aqueous solubility, stability, and corneal permeation of acyl ester prodrugs of ganciclovir. - AAPS PharmSciTech, 4(3), Article 45 (www.pharmscitech.org), 2003.
    • (2003) AAPS PharmSciTech , vol.4 , Issue.3 , pp. 45
    • Tirucherai, G.S.1    Mitra, A.K.2
  • 69
    • 0030847658 scopus 로고    scopus 로고
    • Evaluation of a hydrocortisone/ hydroxypropyl-β-cyclodextrin solution for ocular drug delivery
    • Davies N.M., Wang G., Tucker I.G. - Evaluation of a hydrocortisone/ hydroxypropyl-β-cyclodextrin solution for ocular drug delivery. - Int. J. Pharm., 156, 201-209, 1997.
    • (1997) Int. J. Pharm , vol.156 , pp. 201-209
    • Davies, N.M.1    Wang, G.2    Tucker, I.G.3
  • 70
    • 0033839819 scopus 로고    scopus 로고
    • Considerations in the use of hydroxypropyl-b-cyclodextrin in the formulation of aqueous ophthalmic solutions of hydrocortisone
    • Bary A.R., Tucker I.G., Davies N.M. - Considerations in the use of hydroxypropyl-b-cyclodextrin in the formulation of aqueous ophthalmic solutions of hydrocortisone. - Eur. J. Pharm. Biopharm., 50, 237-244, 2000.
    • (2000) Eur. J. Pharm. Biopharm , vol.50 , pp. 237-244
    • Bary, A.R.1    Tucker, I.G.2    Davies, N.M.3
  • 71
    • 0029885907 scopus 로고    scopus 로고
    • Permeability of a soft steroid, loteprednol etabonate, through an excised rabbit cornea
    • Reddy I.K., Khan M.A., Wu W.M., Bodor N.S. - Permeability of a soft steroid, loteprednol etabonate, through an excised rabbit cornea. - J. Ocul. Pharmacol. Ther., 12, 159-167, 1996.
    • (1996) J. Ocul. Pharmacol. Ther , vol.12 , pp. 159-167
    • Reddy, I.K.1    Khan, M.A.2    Wu, W.M.3    Bodor, N.S.4
  • 73
    • 0030927460 scopus 로고    scopus 로고
    • Influence of α-cyclodextrin and hydroxy-alkylated β-cyclodextrin derivatives on the in vitro corneal uptake and permeation of aqueous pilocarpine-HCI solutions
    • Siefert B., Keipert S. - Influence of α-cyclodextrin and hydroxy-alkylated β-cyclodextrin derivatives on the in vitro corneal uptake and permeation of aqueous pilocarpine-HCI solutions. - J. Pharm. Sci., 86, 716-720, 1997.
    • (1997) J. Pharm. Sci , vol.86 , pp. 716-720
    • Siefert, B.1    Keipert, S.2
  • 74
    • 0027260909 scopus 로고
    • Beta-cyclodextrins enhance bioavailability of pilocarpine
    • Freedman K.A., Klein J.W., Crosson C.E. - Beta-cyclodextrins enhance bioavailability of pilocarpine. - Curr. Eye Res., 12, 641, 1993.
    • (1993) Curr. Eye Res , vol.12 , pp. 641
    • Freedman, K.A.1    Klein, J.W.2    Crosson, C.E.3
  • 75
    • 0030580131 scopus 로고    scopus 로고
    • Interactions between cyclodextrins and pilocarpine - as an example of a hydrophilic drug
    • Keipert S., Fedder J., Böhm A., Hanke B. - Interactions between cyclodextrins and pilocarpine - as an example of a hydrophilic drug. - Int. J. Pharm., 142, 153-162, 1996.
    • (1996) Int. J. Pharm , vol.142 , pp. 153-162
    • Keipert, S.1    Fedder, J.2    Böhm, A.3    Hanke, B.4
  • 76
    • 0028584251 scopus 로고
    • The effect of modified b-cyclodextrin, SBE4-b-CD, on the aqueous solubility and ocular absorption of pilocarpine
    • Järvinen K., Järvinen T., Thompson D.O., Stella V. - The effect of modified b-cyclodextrin, SBE4-b-CD, on the aqueous solubility and ocular absorption of pilocarpine. - Curr Eye Res., 13, 891-905, 1994.
    • (1994) Curr Eye Res , vol.13 , pp. 891-905
    • Järvinen, K.1    Järvinen, T.2    Thompson, D.O.3    Stella, V.4
  • 77
    • 85030513679 scopus 로고    scopus 로고
    • Wheeler L.A, The use of inclusion complexes of prostaglandins with cyclodextrins in the treatment of ocular hypertension, Eur. Pat. No. O 435 682 A3, 1991
    • Wheeler L.A. - The use of inclusion complexes of prostaglandins with cyclodextrins in the treatment of ocular hypertension. - Eur. Pat. No. O 435 682 A3, 1991.
  • 79
    • 0032852111 scopus 로고    scopus 로고
    • Influence of cyclodextrins on the in vitro permeability and in vivo ocular distribution of thalidomide
    • Siefert B., Pleyer U., Müller M., Hartmann C., Keipert S. - Influence of cyclodextrins on the in vitro permeability and in vivo ocular distribution of thalidomide. - J. Ocular Pharmacol. Therap., 15, 429-438, 1999.
    • (1999) J. Ocular Pharmacol. Therap , vol.15 , pp. 429-438
    • Siefert, B.1    Pleyer, U.2    Müller, M.3    Hartmann, C.4    Keipert, S.5
  • 80
    • 0035253635 scopus 로고    scopus 로고
    • Solubilization of tropicamide by hydroxypropyl-β-cyclodextrin and water-soluble polymers: In vitro/in vivo studies
    • Cappello B., Carmignani C., Iervolino M., Rotonda M.I.L., Saettone M.F. - Solubilization of tropicamide by hydroxypropyl-β-cyclodextrin and water-soluble polymers: in vitro/in vivo studies. - Int. J. Pharm., 213, 75-81, 2001.
    • (2001) Int. J. Pharm , vol.213 , pp. 75-81
    • Cappello, B.1    Carmignani, C.2    Iervolino, M.3    Rotonda, M.I.L.4    Saettone, M.F.5
  • 81
    • 0033733495 scopus 로고    scopus 로고
    • Ocular penetration of topical D 9-tetrahydrocannabinol from rabbit corneal or cul-de-sac application site
    • Green K., Kearse E.C. - Ocular penetration of topical D 9-tetrahydrocannabinol from rabbit corneal or cul-de-sac application site. - Curr. Eye Res., 21, 566-570, 2000.
    • (2000) Curr. Eye Res , vol.21 , pp. 566-570
    • Green, K.1    Kearse, E.C.2
  • 82
    • 0033829205 scopus 로고    scopus 로고
    • Effect of vehicle upon in vitro transcorneal permeability and intracorneal content of D9-tetrahydrocannabi-nol
    • Kearse E.C., Green K. - Effect of vehicle upon in vitro transcorneal permeability and intracorneal content of D9-tetrahydrocannabi-nol. - Curr. Eye Res., 20, 496-501, 2000.
    • (2000) Curr. Eye Res , vol.20 , pp. 496-501
    • Kearse, E.C.1    Green, K.2
  • 83
    • 85030512975 scopus 로고    scopus 로고
    • Anderson P.O, Knoben J.E, Troutman W.G, Eds, 9th ed, Appelton & Lange, Stamford
    • th ed., Appelton & Lange, Stamford, 1999.
    • (1999) Handbook of Clinical Drug Data
  • 84
    • 0348025526 scopus 로고    scopus 로고
    • Rowe R.C, Sheskey P.J, Weller P.J, Eds, Pharmaceutical Press, London
    • Rowe R.C., Sheskey P.J., Weller P.J. (Eds.) - Handbook of Pharmaceutical Excipients. - Pharmaceutical Press, London, 2003.
    • (2003) Handbook of Pharmaceutical Excipients
  • 85
    • 85030503252 scopus 로고    scopus 로고
    • Moffat A.C, Osselton M.D, Widdop B, Eds, 3rd ed, Pharmaceutical Press, London
    • rd ed., Vol. 2, Pharmaceutical Press, London, 2004.
    • (2004) Clarke's Analysis of Drugs and Poisons , vol.2
  • 86
    • 34047096267 scopus 로고    scopus 로고
    • Loftsson T., Sigurdsson H.H., Hreinsdóttir D., Konrádsdóttir F., Stefánsson E. - Dexamethasone delivery to posterior segment of the eye. - J. Incl. Phenom. Macroc. Chem., in print, 2007.
    • Loftsson T., Sigurdsson H.H., Hreinsdóttir D., Konrádsdóttir F., Stefánsson E. - Dexamethasone delivery to posterior segment of the eye. - J. Incl. Phenom. Macroc. Chem., in print, 2007.


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