α-Amino acid derivatives as proton pump inhibitors and potent anti-ulcer agents

European Journal of Medicinal Chemistry

Volumn 42, Issue 3, 2007, Pages 386-393

  Sharma, Preeti ^a   Singh, Sangeeta ^a   Siddiqui, Tanveer I ^a   Singh, Vishnu S ^a   Kundu, Bijoy ^a   Prathipati, Philip ^a   Saxena, Anil K ^a   Dikshit, Dinesh K ^a   Rastogi, Leena ^a   Dixit, Chetna ^a   Gupta, M B ^a   Patnaik, G K ^a   Dikshit, Madhu ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Amino acids; Anti ulcer; H+ K+ ATPase; Pylorus ligation

Indexed keywords

5 (2 PHENYLETHENYL) 2 OXOXAZOLIDINE 4 CARBOXYLIC ACID; AMINO ACID DERIVATIVE; ANTIULCER AGENT; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; OMEPRAZOLE; PROTON PUMP INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; ENZYME INHIBITION; EXPERIMENTAL MODEL; HYDROPHOBICITY; IC 50; IN VIVO STUDY; NONHUMAN; PYLORUS LIGATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; STOMACH ULCER;

4-NITROPHENYLPHOSPHATASE; ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMALS; ANTI-ULCER AGENTS; ENZYME INHIBITORS; GASTRIC ACIDITY DETERMINATION; GASTRIC MUCOSA; LIGATION; MALE; MICROSOMES; MODELS, MOLECULAR; OMEPRAZOLE; PROTON PUMPS; PYLORUS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; RATS, SPRAGUE-DAWLEY; VESICULAR TRANSPORT PROTEINS;

EID: 33847400566     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.08.016     Document Type: Article

References (36)

1. Michael Wolfe M., and Andrew H.S. N. Engl. J. Med. 319 (1988) 1707
2. Sachs G. Biochim. Biophys. Acta 805 (1984) 181
3. Okebe S., and Takagi K. Jpn. J. Pharmacol. (1968) 18
4. Susumu O., Takeuchis K., Nakamura K., and Takagi K. Jpn. J. Pharmacol. 24 (1974) 363
5. Baak L.C., Jansen J.B., and Lamers C.B. Dig. Dis. Sci. 35 5 (1990) 596
6. Feig W.B., and Nahrwold D.L. Surgery 104 2 (1988) 412
7. Ignatenko L.G. Vopr. Pitan. 3 (1984) 51
8. Yang E.Y., and Nahrwold D.L. Surgery 114 5 (1993) 915
9. Baak L.C., Jansen J.B., and Lamers C.B. Infusions therapie 17 (1990) 321
10. Schmidtler J., Schepp W., Schusdziarra V., and Classen M. Digestion 44 4 (1989) 211
11. Tariq M., and Al Mougary A.R. Res. Commun. Mol. Pathol. Pharmacol. 97 2 (1997) 171
12. Bulbuller N., Akkus M.A., Ilhan Y.S., Baysal F., Ozercan I., Aygen E., and Kirkil C. Ulus. Travma Derg. 9 2 (2003) 90-95
13. Brzozowska I., Konturek P.C., Brzozowski T., Konturek S.J., Kwiecien S., Pajdo R., Drozdowicz D., Pawlik M., Ptak A., and Hahn E.G. J. Pineal Res. 32 3 (2002) 149-162
14. Ohta Y., and Nishida K. Clin. Exp. Pharmacol. Physiol. 29 (2002) 32-38
15. Kalia N., Bardhan K.D., Reed M.W., Jacob S., and Brown N.J. J. Gastroenterol Hepatol. 15 (2000) 915-924
16. Hariganesh K., and Prathiba J. J. Pharm. Pharmacol. 52 (2000) 1519-1522
17. Del Valle J., and Yamada T. J. Clin. Invest. 85 (1990) 139
18. Richardson C.T., and Feldman M. Regul. Pept. 10 (1995) 339
19. He S.W., Shen K.Q., He Yjxie B., and Zhao Y.M. World J. Gastroenterol. 5 (1999) 408
20. Magnous R., and Bali J.P. Regul. Pept. 7 (1983) 233
21. Kobayashi T., Zinchuk V.S., Garcia Del Saz E., Yamasaki J.Y., Kataoka S., Ekeda T., Tsunavaki S., and Seguchi H. Histol. Histopathol. 15 (2000) 1067
22. Dikshit D.K., and Sangeeta S. Tetrahedron Lett. 29 (1988) 3109
23. Dikshit D.K., and Maheshweri A. Tetrahedron Lett. 36 (1995) 6131
24. Campaigne E., and Matthews D.M. J. Heterocycl. Chem. 12 (1975) 391
25. D.K. Dikshit, S. Singh, G.K. Patnaik, R.C. Srimal, B.N. Dhawan, Indian Patent No. 178841.
26. Soai K.S., and Ookawa A. J. Chem. Soc. Perkin Trans. 1 (1986) 759
27. Pavash P.L., Sparrow E., and Gathe J.C. J. Am. Chem. Soc. 72 (1950) 1415
28. Yan R., Sun Y., and Sun R. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 11 (1995) 189
29. Houdijk A., Van Leeuwem P.A., and Boermeesterm M.A. Am. J. Physiol. 267 (1994) G 1035
30. Brzozowski T., Konturek S.J., and Sliwowski Z. J. Gasterenterol. 32 (1997) 442
31. Insight II, Version 2.3.0, San Diego Biosym Technologies, 1993.
32. Stewart J.J.P. J. Comput. Aided Mol. Des. 4 (1990) 1
33. Zuo F.R., Li S.G., and Lin Z.H. Biochem. Biophys. Acta 23 (1991) 196
34. Lee H.C., and Forte J.G. Biochim. Biophys. Acta 508 (1978) 339
35. Keeling D.J., Laing S.M., and Senn-Bilfinger. J. Biochem. Pharmacol. 42 (1988) 123-130
36. Shay M., Kamrov S.A., Fels D., Meraze O., Gruestein H., and Siplet H. Gastroenterology 5 (1945) 43