Diterpenes inhibit IL-12 production by DC and enhance Th2 cells polarization

Biochemical and Biophysical Research Communications

Volumn 355, Issue 3, 2007, Pages 603-610

  Takei, Masao ^a   Umeyama, Akemi ^b   Arihara, Shigenobu ^b  

^a Research Center Borstel   (Germany)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Autoimmune diseases; Dendritic cells; Diterpenes; Th2 response

Indexed keywords

12 HYDROXY 6,7 SECOABIETA 8,11,13 TRIENE 6,7 DIAL; DITERPENE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; PROTEIN P70; SECOFERRUGINOL; SUGIOL; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; CELL ACTIVATION; CELL MATURATION; CYTOKINE RELEASE; DENDRITIC CELL; EFFECTOR CELL; HUMAN; HUMAN CELL; JAPANESE CEDAR; MEMBRANE POLARIZATION AND DEPOLARIZATION; MEMBRANE TRANSPORT; PRIORITY JOURNAL; T LYMPHOCYTE;

ANTIGENS, CD; CELL POLARITY; DENDRITIC CELLS; DITERPENES; HUMANS; IMMUNOGLOBULINS; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; TH2 CELLS;

CRYPTOMERIA JAPONICA;

EID: 33847357834     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.01.157     Document Type: Article

References (31)

1. Moser M., and Murphy K.M. Dendritic cell regulation of TH1-TH2 development. Nat. Immunol. 1 (2000) 199-205
2. Romagnani S. Lymphokine production by human T cells in disease state. Annu. Rev. Immunol. 12 (1994) 227-257
3. Kuchroo V.K., Dasa M.P., Brown A., Ranger A.M., Zamvil S.S., Sobel R.A., Weiner H.L., Nabavi N., and Glimcheri L.H. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 development pathways: application to autoimmune disease therapy. Cell 80 (1995) 707-713
4. Lederer J.A., Perez V.L., Desroches L., Kim S.M., Abbas A., and Lichtman A.H.I. Cytokine transcriptional events during helper T cell subset differentiation. J. Exp. Med. 184 (1996) 397-406
5. Tao X., Grant C., Constant S., and Bottomly K. Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding. J. Immunol. 158 (1997) 4237-4244
6. Iezzi G., Scotet E., Scheidegger D., and Lanzavecchia A. The interplay between the duration of TCR and cytokine signaling determines T cell polarization. Eur. J. Immunol. 29 (1997) 4092-4101
7. Tanaka H., Demeure CE., Rubio M., Delespesse G., and Sarfati M. Human monocyte-derived dendritic cells induce naïve T cell differentiation into T helper cell type 2 (Th2) or TH1/Th2 effectors: role of stimulator/responder ratio. J. Exp. Med. 192 (2000) 405-411
8. Vieira P.L., de Jong D.C., Wierenga F.A., Kapsenberg M.L., and Kalinski P. Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction. J. Immunol. 164 (2000) 4507-4512
9. O'garra A., and Murphy K. T-cell subsets in autoimmunity. Curr. Opin. 5 (1993) 880-886
10. Romagnani S. Th1 and Th2 in human diseases. Clin. Immunol. Immunopathol. 80 (1996) 225-235
11. D'elios M., and Del Prete G. Th1/Th2 balance in human disease. Transplant. Proc. 30 (1998) 2372-2379
12. Hayashi M., Martinez O.M., Garcia-Kennedy R., So S., Esquivel C.O., and Krams S.M. Expression of cytokines and immune mediators during chronic liver allograft rejection. Trasnplantation 60 (1995) 1533-1538
13. Lafaille J.J. The role of helper T cell subsets in autoimmune diseases. Cytokine Growth Factor Rev. 9 (1998) 139-151
14. Grewe M., Bruijnzeel-Koomen C.A., Schope E., Thepen T., Langeveld-Wildschut A.G., Ruzicka T., and Krutmann J. A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis. Immunol. Today 19 (1998) 359-361
15. Cella M., Scheidegger D., Palmer-Lehmann K., Lane P., Lanzavecchia A., and Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184 (1996) 747-752
16. Cella M., Salio M., Sakakibara Y., Langen H., Julkunen I., and Lanzavecchia A. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189 (1999) 821-829
17. Hartmann G., Weiner G.J., and Krieg A.M. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. Proc. Natl. Acad. Sci. USA 96 (1999) 9305-9310
18. de Jong E.C., Vieira P.L., Kalinski P., Schuitemaker J.H.N., Tanaka Y., Wierenga E.A., Yazdanbakhsh M., and Kapsenberg M.L. Microcompounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse Th cell-polarizing signal. J. Immunol. 168 (2002) 1704-1709
19. Trinchieri G. Proinflammatory and immunoregulatory functions of interleukin-12. Int. Rev. Immunol. 16 (1998) 365-396
20. Adorini L. Interleukin-12, a key cytokine in Th1-mediated autoimmune diseases. Cell. Mol. Life. Sci. 55 (1999) 1610-1625
21. Shimizu M., Tsuji J., Sugawa H., Fikamura H., Tannami S., Hayashi T., Munehisa A., and Morita N. Anti-inflammatory constituents of topically applied crude drugs. II. Constituents and anti-inflammatory effect of Cryptomeria japonica D Don. Chem. Pharm. Bull. 36 (1998) 3967-3973
22. Claeson P., Zygmunt P., and Hogstatt E.D. Calcium antagonistic properties of the sesquiterpene T-cadinol: a comparison with nimodipine in the isolated rat aorta. Pharmacol. Toxicol. 69 (1991) 73-177
23. Chao C.P., Hua K.F., Su H.Y.C., and Chang S.T. Anti-inflammatory activity of sugiol, a diterpene isolated from Calocedrus formosana bark. Planta Med. 71 (2005) 300-3005
24. Arihara S., Umeyama A., Bando S., Imoto S., Ono M., Tani M., and Yoshikawa K. A new abietane and two dimeric abietane diterpens from the Black Heartwood of Cryptomeria japonica. Chem. Pharm. Bull. 52 (2004) 354-358
25. Grage-Griebenow E., Lorenzen D., Fetting R., Flad H.D., and Ernst M. Phenotypical and functional characterisation of FC( receptor 1 (CD64)-negative Mo, a minor human mo subpopulation with high accessory and antiviral activity. Eur. J. Immunol. 23 (1993) 3126-3131
26. Takei M., Tachikawa E., Hasegawa H., and Lee J.J. Dendritic cells maturation promoted by a potent Th1 polarization. Biochem. Pharmacol. 68 (2004) 441-452
27. Delespesse G., Ohshima Y., Shu U., Yang LP., Demeure C., Wu Y., Byun D.G., and Sarfat M. Differentiation of naïve human CD4 T cells into Th2/Th1 effectors. Allergol. Int. 46 (1997) 63-72
28. Brunda M.J., Luistro L., Warrier R.R., Wright RB., Hubbard B.R., Murphy M., Wolf S.F., and Gately M.K. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J. Exp. Med. 78 (1993) 1223-1226
29. Caspi R.P. IL-12 in autoimmunity. Clin. Immunol. Immunopathol. 88 (1998) 4-13
30. Kalinski P., Hilkens C.M., Wierenga E.A., and Kapsenberg M.L. T cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol. Today 20 (1999) 561-567
31. Oshima Y., Yang L.P., Uchiyama T., Tanaka Y., Baum P., Sergerie M., Hermann P., and Delespesse G. OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naïve human CD (+) T cells into high IL-4-producting effectors. Blood 92 (1998) 3338-3345