Anti-inflammatory activity of sugiol, a diterpene isolated from Calocedrus formosana bark

Planta Medica

Volumn 71, Issue 4, 2005, Pages 300-305

  Chao, Kuo Ping ^a   Hua, Kuo Feng ^b   Hsu, Hsien Yeh ^b   Su, Yu Chang ^c   Chang, Shang Tzen ^d  

^a CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIWAN FORESTRY RESEARCH INSTITUTE   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Anti inflammatory activity; Calocedrus formosana; Cupressaceae; IL 1 ; MAPKs; Sugiol; TNF

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; ANTIINFLAMMATORY AGENT; CALOCEDRUS FORMOSANA EXTRACT; CYTOKINE; DITERPENE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUGIOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BARK; CALOCEDRUS FORMOSANA; CONTROLLED STUDY; CUPRESSACEAE; DOSE RESPONSE; DRUG EFFICACY; DRUG ISOLATION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; INFLAMMATION; LOW DRUG DOSE; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; PURIFICATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CUPRESSACEAE; CYTOKINES; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PHYTOTHERAPY; PICRATES; PLANT BARK; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

ANIMALIA; CALOCEDRUS FORMOSANA; CUPRESSACEAE; MURINAE;

EID: 18744405109     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-864094     Document Type: Article

References (17)

1. Iwamoto M, Minami T, Tokuda H, Ohtsu H, Tanaka R. Potential antitumor promoting diterpenoids from the stem bark of Thuja standishii. Planta Medica 2003; 69: 69-72
2. Tezuka Y, Kasimu R, Basnet P, Namba T, Kadota S. Aldose reductase inhibitory constituents of the root of Salvia miltiorrhiza Bunge. Chem Pharm Bull 1997; 45: 1306-11
3. Politi M, Braca A, Tommasi ND, Morelli I, Manunta A, Battinelli L, Maxxanti G. Antimicrobial diterpenes from the seeds of Cephalotaxus harringtonia var. drupacea. Planta Medica 2003; 69: 468-70
4. Medzhitov R, Janeway CA. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997; 91: 295-8
5. Christian RH, Chris Whitfield. Lipolysaccharide endotoxins. Annu Rev Biochem 2002; 71: 635-700
6. Hsu HY, Wen MH. Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression. J Biol Chem 2002; 277: 22 131-9
7. Wang SY, Wu JH, Shyur LF, Kuo YH, Chang ST. Antioxidant activity of abietane-type diterpenes from Taiwania crytomerioides Hayata. Holzforschung 2002; 56: 487-92
8. Wang YY, Khoo KH, Chen ST, Lin CC, Wong CH, Lin CH. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorg Med Chem 2002; 10: 1057-62
9. Wan CP, Myung E, Lau BH. An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes. J Immunol Methods 1993; 159: 131-8
10. Wang SY, Wu JH, Cheng SS, Lo CP, Chang HN, Shyur, Chang ST. Antioxidant activity of extracts from Calocedrus formosana leaf, bark and heartwood. J. Wood Sci 2004; 50: 422-6
11. Priyadarsini KI, Maity DK, Naik GH, Kumar MS, Unnikrishnan MK, Satav JG, Mohan H. Role of phenolic 0-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin. Free Radic Biol Med. 2003; 35: 475-84
12. Ropert C, Almeida IC, Closel M, Travassos LR, Ferguson MA, Cohen P, Gazzinelli RT. Requirement of mitogen-activated protein kinases and 1 kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide. J Immunol 2001; 166: 3423-31
13. Ware CF. The TNF superfamily. Cytokine Growth Factor Rev 2003; 14: 81-4
14. Ulubelen A, Topçu G, Sönmez U, Choudhary MI, Atta-Ur-Rahman. Abietane diterpenes from Salvia napifolia. Phytochemistry 1995; 40; 861-4.
15. Kim KM, Kwon YG, Chung HT, Yun YG, Pae HO, Han JA, Ha KS, Kim TW, Kim YM. Methanol extracts of Cordyceps pruinosa inhibits in vitro and in vivo inflammatory mediators by suppressing NF-κB activation. Toxicology and Applied Pharmacology 2003; 190: 1-8
16. Jang SI, Jeong SI, Kim KJ, Kim HJ, Yu HH, Park R, Kim HM, You YO. Tanshinone IIA from Salvia miltiorrhiza inhibits inducible nitric oxide synthase expression and production of TNF-α, IL-1β and IL-6 protein in activated raw 264.7 cells. Planta Medica 2003; 69: 1057-9
17. Haddad JJ, Land SC. Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis. Br J Pharmacol 2002; 135: 520-36