Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells

British Journal of Cancer

Volumn 96, Issue 4, 2007, Pages 583-590

  Zhu, T ^a   Guo, J ^a   Collins, L ^a   Kelly, J ^a   Xiao, Z J ^b   Kim, S H ^c   Chen, C Y ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Kyung Hee University   (South Korea)

Author keywords

Apoptosis; Caspases; ER; PL

Indexed keywords

ANDROGEN RECEPTOR; CASPASE 2; CASPASE 8; CASPASE INHIBITOR; MUTANT PROTEIN; PHELLINUS LINTEUS EXTRACT; PLANT EXTRACT; PROTEIN BID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL SPECIFICITY; CELL STRAIN LNCAP; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SENSITIVITY; EFFECTOR CELL; HUMAN; HUMAN CELL; MALE; MUSHROOM; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRESS;

APOPTOSIS; BASIDIOMYCOTA; CASPASE 2; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MALE; NEOPLASM INVASIVENESS; POLYSACCHARIDES; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; UP-REGULATION;

EID: 33847216158     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603595     Document Type: Article

References (41)

1. Bhornberry NA, Lazebnik Y (1998) Caspases: enemies within. Science 281: 1312-1316
2. Borchers AT, Stern JS, Hackman RM, Keen CL, Gershwin EM (1999) Minireview: mushrooms, tumors and immunity. Soc Exp Biol Med 221: 281-293
3. Breckenridge DG, Germain M, Mathai JP, Nguyen M, Shore GC (2003) Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 22: 8608-8618
4. Chae H, Kim H, Xu C, Bailly-Maitre B, Krajewska M, Krajewski S, Banares S, Cui J, Digicaylioglu M, Ke N, Kitada S, Monosov E, Thomas M, Kress CL, Babendure JR, Tsien RY, Lipton SA, Reed JC (2004) BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell 15: 355-366
5. Chen DC, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL (2004) Molecular determinants of resistance to antiandrogen therapy. Nat Med 10: 33-39
6. Chihara G, Maeda Y, Hamuro J, Sasaki T, Fumiko F (1969) Inhibition of mouse sarcoma 180 by polysaccharides from Lentinus edodes. Nature 222: 687-688
7. Chung KS, Choi EC, Kim BK, Kim YS, Park YK (1982) The constituents and culture of Korean Basidiomycetes: antitumor polysaccharides from the cultured mycelia of some Basidiomycetes. Arch Pharm Res 5: 17-20
8. Collins L, Zhu T, Guo J, Xiao ZJ, Chen C-Y (2006) Phellinus linteus sensitizes apoptosis induced by doxorubicin in prostate cancer. Br J Cancer 95: 282-288
9. Cun Z, Mizuno T, Ito H, Shimura K, Sumiya T, Kawade M (1994) Antitumor activity and immunological property of polysaccharides from the mycelium of liquid-cultured Grifola frondosa. J Jpn Soc Food Sci Technol 41: 724-732
10. Debes JD, Tindall DJ (2004) Mechanisms of androgen-refractory prostate cancer. N Engl J Med 351: 1488-1490
11. Demaurex N, Distelhorst C (2003) Apoptosis-the calcium connection. Science 300: 65-67
12. Droin N, Bichat F, Rebe C, Wotawa A, Sordet O, Hammann A, Bertrand R, Solary E (2001) Involvement of caspase 2 long isoform in Fas-mediated cell death of human leukemic cells. Neoplasia 97: 1835-1844
13. Feldman BJ, Feldman D (2001) The development of androgen-independent prostate cancer. Nat Rev Cancer 1: 34-35
14. Forman MS, Lee VM, Trojanowski JQ (2003) Unfolding, pathways in neurodegenerative disease. Trends Neurosci 26: 407-410
15. Grossmann ME, Huang H, Tindall DJ (2001) Androgen receptor signaling in androgen-refractory prostate cancer. J Natl Cancer Inst 93: 1687-1697
16. Guo J, Zhu T, Collins L, Xiao ZJ, Kim S-H, Chen C-Y (2006) Modulation of lung cancer growth arrest and apoptosis by phellinus linteus. Mol Carcinog in press
17. Han SB, Lee CW, Jeon YJ, Hong ND, Yoo ID, Yang K-H, Kim HM (1999) The inhibitory effect of polysaccharide isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacology 41: 157-164
18. Harvey NL, Butt AJ, Kumar S (1997) Functional activation of Nedd2/ICH-1 (caspase 2) is an early process in apoptosis. J Biol Chem 272: 13134-13139
19. Herr I, Debatin KM (2001) Cellular stress response and apoptosis in cancer therapy. Blood 98: 2603-2614
20. Kaufman RJ (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13: 1211-1233
21. Linja MJ, Savinainen KJ, Saramaki OR, Tamella TLJ, Vessella RL, Visakorpi T (2001) Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer. Cancer Res 61: 3550-3555
22. Lorenzen K, Anke T (1998) Biologically active metabolites from basidiomycetes. Curr Org Chem 2: 329-364
23. Ma Y, Hendershot LM (2001) The unfolding tale of the unfolded protein response. Cell 107: 827-830
24. Ma Y, Hendershot LM (2004) ER chaperone functions during normal and stress conditions. J Chem Neuroanat 28: 51-65
25. Mancini M, Machamer CE, Roy S, Nicholson DW, Thornberry NA, Casciola-Rosen LA, Rosen A (2000) Caspase 2 is localized at the Golgi complex and cleaves Golgin-160 during apoptosis. J Cell Biol 149: 603-612
26. Marcelli M, Cunningham GR, Walkup M (1999) Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase 7 as a new gene therapy strategy for prostate cancer. Cancer Res 59: 382-390
27. Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y (2002) An endoplasmic reticulum stress-specific caspase cascade in apoptosis. J Biol Chem 277: 34287-34294
28. Nelson WG, De Marzo AM, Issacs WB (2003) Prostate cancer. N Engl J Med 349: 366-381
29. Nicholson DW, Thomberry NA (1997) Caspases: killer proteases. Trends Biochem Sci 22: 299-306
30. Patil C, Walter P (2001) Intracellualr signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol 13: 349-355
31. Rokhlin OW, Taghiyev AF, Guseva NV, Glover RA, Chumakov PM, Kravchenko JE, Cohen MB (2005) Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP. Oncogene 24: 6773-6784
32. Rutkowski DT, Kaufman RJ (2004) A trip to the ER: coping with stress. Trends Cell Biol 14: 20-28
33. Schmitz I, Kirchhoff S, Krammer PH (2000) Regulation of death receptor-mediated apoptosis pathways. Int J Biochem Cell Biol 32: 1123-1136
34. Schroder M, Kaufman RJ (2005) The mammalian unfolded protein response. Annu Rev Biochem 74: 739-789
35. Shi Y (2002) Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell 9: 459-470
36. Song KS, Cho SM, Lee IK, Kim HM, Han SB, Ko KS, Yoo ID (1995) B-lymphocyte-stimulating polysaccharide from mushroom Phellinus linteus. Chem Pharm Bull 43: 2105-2108
37. Sriburi R, Jackowski S, Mori K, Brewer JW (2004) XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J Cell Biol 167: 35-41
38. Susin SA, Lorenzo HK, Zamzami N (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397: 441-446
39. Takuma K, Yan SS, Stem DM, Yamada K (2005) Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease. J Phamacol Sci 97: 312-316
40. Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vailancourt JP, Chaman KT, Nicholson DW (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. J Biol Chem 272: 17907-17911
41. Wasser SP (2002) Medicinal mushrooms as a source of antitumor and immuno-modulating polysaccharides. Appl Microbiol Biotech 60: 258-274