-
1
-
-
0022272493
-
Determination of glutathione and glutathione disulfide in biological samples
-
Anderson M.E. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 113 (1985) 548-555
-
(1985)
Methods Enzymol.
, vol.113
, pp. 548-555
-
-
Anderson, M.E.1
-
2
-
-
0025311288
-
Epithelial transport of drugs in cell culture. I. A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells
-
Artursson P. Epithelial transport of drugs in cell culture. I. A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells. J. Pharm. Sci. 79 (1990) 476-482
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 476-482
-
-
Artursson, P.1
-
3
-
-
0002425059
-
Studying transport processes in absorptive epithelia
-
Shaw A.J. (Ed), Oxford University Press, New York
-
Artursson P., Karlsson J., Ocklind G., and Schipper N. Studying transport processes in absorptive epithelia. In: Shaw A.J. (Ed). Epithelial Cell Culture (1996), Oxford University Press, New York 111-133
-
(1996)
Epithelial Cell Culture
, pp. 111-133
-
-
Artursson, P.1
Karlsson, J.2
Ocklind, G.3
Schipper, N.4
-
4
-
-
0034949951
-
Metabolism, toxicokinetics and hemoglobin adduct formation in rats following subacute and subchronic acrylamide dosing
-
Barber D.S., Hunt J.R., Ehrich M.F., Lehning E.J., and LoPachin R.M. Metabolism, toxicokinetics and hemoglobin adduct formation in rats following subacute and subchronic acrylamide dosing. Neurotoxicology 22 (2001) 341-353
-
(2001)
Neurotoxicology
, vol.22
, pp. 341-353
-
-
Barber, D.S.1
Hunt, J.R.2
Ehrich, M.F.3
Lehning, E.J.4
LoPachin, R.M.5
-
5
-
-
0141884785
-
Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells
-
Borlak J., and Zwadlo C. Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells. Xenobiotica 33 (2003) 927-943
-
(2003)
Xenobiotica
, vol.33
, pp. 927-943
-
-
Borlak, J.1
Zwadlo, C.2
-
6
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
7
-
-
0030787532
-
A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model
-
Delie F., and Rubas W. A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model. Crit. Rev. Ther. Drug Carrier Syst. 14 (1997) 221-286
-
(1997)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.14
, pp. 221-286
-
-
Delie, F.1
Rubas, W.2
-
8
-
-
19944433898
-
Human exposure and internal dose assessments of acrylamide in food
-
Dybing E., Farmer P.B., Andersen M., Fennell T.R., Lalljie S.P., Muller D.J., Olin S., Petersen B.J., Schlatter J., Scholz G., Scimeca J.A., Slimani N., Tornqvist M., Tuijtelaars S., and Verger P. Human exposure and internal dose assessments of acrylamide in food. Food Chem. Toxicol. 43 (2005) 365-410
-
(2005)
Food Chem. Toxicol.
, vol.43
, pp. 365-410
-
-
Dybing, E.1
Farmer, P.B.2
Andersen, M.3
Fennell, T.R.4
Lalljie, S.P.5
Muller, D.J.6
Olin, S.7
Petersen, B.J.8
Schlatter, J.9
Scholz, G.10
Scimeca, J.A.11
Slimani, N.12
Tornqvist, M.13
Tuijtelaars, S.14
Verger, P.15
-
9
-
-
0029831341
-
A ferric reductase activity is found in brush border membrane vesicles isolated from Caco-2 cells
-
Ekmekcioglu C., Feyertag J., and Marktl W. A ferric reductase activity is found in brush border membrane vesicles isolated from Caco-2 cells. J. Nutr. 126 (1996) 2209-2217
-
(1996)
J. Nutr.
, vol.126
, pp. 2209-2217
-
-
Ekmekcioglu, C.1
Feyertag, J.2
Marktl, W.3
-
10
-
-
18144417833
-
Metabolism and hemoglobin adduct formation of acrylamide in humans
-
Fennell T.R., Sumner S.C., Snyder R.W., Burgess J., Spicer R., Bridson W.E., and Friedman M.A. Metabolism and hemoglobin adduct formation of acrylamide in humans. Toxicol. Sci. 85 (2005) 447-459
-
(2005)
Toxicol. Sci.
, vol.85
, pp. 447-459
-
-
Fennell, T.R.1
Sumner, S.C.2
Snyder, R.W.3
Burgess, J.4
Spicer, R.5
Bridson, W.E.6
Friedman, M.A.7
-
12
-
-
33644764646
-
Toxicokinetics of acrylamide in humans after ingestion of a defined dose in a test meal to improve risk assessment for acrylamide carcinogenicity
-
Fuhr U., Boettcher M.I., Kinzig-Schippers M., Weyer A., Jetter A., Lazar A., Taubert D., Tomalik-Scharte D., Pournara P., Jakob V., Harlfinger S., Klaassen T., Berkessel A., Angerer J., Sorgel F., and Schomig E. Toxicokinetics of acrylamide in humans after ingestion of a defined dose in a test meal to improve risk assessment for acrylamide carcinogenicity. Cancer Epidemiol. Biomarkers Prev. 15 (2006) 266-271
-
(2006)
Cancer Epidemiol. Biomarkers Prev.
, vol.15
, pp. 266-271
-
-
Fuhr, U.1
Boettcher, M.I.2
Kinzig-Schippers, M.3
Weyer, A.4
Jetter, A.5
Lazar, A.6
Taubert, D.7
Tomalik-Scharte, D.8
Pournara, P.9
Jakob, V.10
Harlfinger, S.11
Klaassen, T.12
Berkessel, A.13
Angerer, J.14
Sorgel, F.15
Schomig, E.16
-
13
-
-
0036078541
-
Transport mechanisms of nicotine across the human intestinal epithelial cell line Caco-2
-
Fukada A., Saito H., and Inui K. Transport mechanisms of nicotine across the human intestinal epithelial cell line Caco-2. J. Pharmacol. Exp. Ther. 302 (2002) 532-538
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 532-538
-
-
Fukada, A.1
Saito, H.2
Inui, K.3
-
14
-
-
0001520606
-
A fine-structure genetic and chemical study of the enzyme alkaline phosphatase of E. coli. I. Purification and characterization of alkaline phosphatase
-
Garen A., and Levinthal C. A fine-structure genetic and chemical study of the enzyme alkaline phosphatase of E. coli. I. Purification and characterization of alkaline phosphatase. Biochim. Biophys. Acta 38 (1960) 470-483
-
(1960)
Biochim. Biophys. Acta
, vol.38
, pp. 470-483
-
-
Garen, A.1
Levinthal, C.2
-
15
-
-
25844501905
-
Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
-
Ghanayem B.I., Witt K.L., Kissling G.E., Tice R.R., and Recio L. Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect. Mutat. Res. 578 (2005) 284-297
-
(2005)
Mutat. Res.
, vol.578
, pp. 284-297
-
-
Ghanayem, B.I.1
Witt, K.L.2
Kissling, G.E.3
Tice, R.R.4
Recio, L.5
-
16
-
-
0011939912
-
Lethality testing
-
Gad S.C. (Ed), Raven Press, New York
-
Guzzie P.J. Lethality testing. In: Gad S.C. (Ed). In vitro Toxicology (1994), Raven Press, New York 57-86
-
(1994)
In vitro Toxicology
, pp. 57-86
-
-
Guzzie, P.J.1
-
17
-
-
0016275313
-
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
-
Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jakoby, W.B.3
-
18
-
-
0025118126
-
Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2
-
Hidalgo I.J., and Borchardt R.T. Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2. Biochim. Biophys. Acta 1028 (1990) 25-30
-
(1990)
Biochim. Biophys. Acta
, vol.1028
, pp. 25-30
-
-
Hidalgo, I.J.1
Borchardt, R.T.2
-
19
-
-
0025358551
-
Transport of bile acids in a human intestinal epithelial cell line, Caco-2
-
Hidalgo I.J., and Borchardt R.T. Transport of bile acids in a human intestinal epithelial cell line, Caco-2. Biochim. Biophys. Acta 1035 (1990) 97-103
-
(1990)
Biochim. Biophys. Acta
, vol.1035
, pp. 97-103
-
-
Hidalgo, I.J.1
Borchardt, R.T.2
-
20
-
-
0024593744
-
Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
-
Hidalgo I.J., Raub T.J., and Borchardt R.T. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96 (1989) 736-749
-
(1989)
Gastroenterology
, vol.96
, pp. 736-749
-
-
Hidalgo, I.J.1
Raub, T.J.2
Borchardt, R.T.3
-
23
-
-
0043212100
-
Choline uptake in human intestinal Caco-2 cells is carrier-mediated
-
Kamath A.V., Darling I.M., and Morris M.E. Choline uptake in human intestinal Caco-2 cells is carrier-mediated. J. Nutr. 133 (2003) 2607-2611
-
(2003)
J. Nutr.
, vol.133
, pp. 2607-2611
-
-
Kamath, A.V.1
Darling, I.M.2
Morris, M.E.3
-
25
-
-
0031810016
-
Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines
-
Lampen A., Bader A., Bestmann T., Winkler M., Witte L., and Borlak J.T. Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines. Xenobiotica 28 (1998) 429-441
-
(1998)
Xenobiotica
, vol.28
, pp. 429-441
-
-
Lampen, A.1
Bader, A.2
Bestmann, T.3
Winkler, M.4
Witte, L.5
Borlak, J.T.6
-
27
-
-
0033996982
-
Diphenhydramine transport by pH-dependent tertiary amine transport system in Caco-2 cells
-
Mizuuchi H., Katsura T., Ashida K., Hashimoto Y., and Inui K. Diphenhydramine transport by pH-dependent tertiary amine transport system in Caco-2 cells. Am. J. Physiol. Gastrointest. Liver Physiol. 278 (2000) G563-G569
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.278
-
-
Mizuuchi, H.1
Katsura, T.2
Ashida, K.3
Hashimoto, Y.4
Inui, K.5
-
28
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
29
-
-
0028578004
-
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport
-
Muller M., Meijer C., Zaman G.J., Borst P., Scheper R.J., Mulder N.H., de Vries E.G., and Jansen P.L. Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 13033-13037
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 13033-13037
-
-
Muller, M.1
Meijer, C.2
Zaman, G.J.3
Borst, P.4
Scheper, R.J.5
Mulder, N.H.6
de Vries, E.G.7
Jansen, P.L.8
-
30
-
-
32644436135
-
Impact of extracellular protein binding on passive and active drug transport across Caco-2 cells
-
Neuhoff S., Artursson P., Zamora I., and Ungell A.L. Impact of extracellular protein binding on passive and active drug transport across Caco-2 cells. Pharm. Res. 23 (2006) 350-359
-
(2006)
Pharm. Res.
, vol.23
, pp. 350-359
-
-
Neuhoff, S.1
Artursson, P.2
Zamora, I.3
Ungell, A.L.4
-
31
-
-
0036890402
-
Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells
-
Nkabyo Y.S., Ziegler T.R., Gu L.H., Watson W.H., and Jones D.P. Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells. Am. J. Physiol. Gastrointest. Liver Physiol. 283 (2002) G1352-G1359
-
(2002)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.283
-
-
Nkabyo, Y.S.1
Ziegler, T.R.2
Gu, L.H.3
Watson, W.H.4
Jones, D.P.5
-
33
-
-
0024789567
-
Time-dependent activity and expression of glutathione S-transferases in the human colon adenocarcinoma cell line Caco-2
-
Peters W.H., and Roelofs H.M. Time-dependent activity and expression of glutathione S-transferases in the human colon adenocarcinoma cell line Caco-2. Biochem. J. 264 (1989) 613-616
-
(1989)
Biochem. J.
, vol.264
, pp. 613-616
-
-
Peters, W.H.1
Roelofs, H.M.2
-
34
-
-
0037252475
-
Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines
-
Pfrunder A., Gutmann H., Beglinger C., and Drewe J. Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines. J. Pharm. Pharmacol. 55 (2003) 59-66
-
(2003)
J. Pharm. Pharmacol.
, vol.55
, pp. 59-66
-
-
Pfrunder, A.1
Gutmann, H.2
Beglinger, C.3
Drewe, J.4
-
35
-
-
6344242987
-
Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells
-
Prime-Chapman H.M., Fearn R.A., Cooper A.E., Moore V., and Hirst B.H. Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. J. Pharmacol. Exp. Ther. 311 (2004) 476-484
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, pp. 476-484
-
-
Prime-Chapman, H.M.1
Fearn, R.A.2
Cooper, A.E.3
Moore, V.4
Hirst, B.H.5
-
36
-
-
0033538870
-
Insoluble gamma-tubulin-containing structures are anchored to the apical network of intermediate filaments in polarized Caco-2 epithelial cells
-
Salas P.J. Insoluble gamma-tubulin-containing structures are anchored to the apical network of intermediate filaments in polarized Caco-2 epithelial cells. J. Cell Biol. 146 (1999) 645-658
-
(1999)
J. Cell Biol.
, vol.146
, pp. 645-658
-
-
Salas, P.J.1
-
37
-
-
2942530368
-
Reduction of acrylamide uptake by dietary proteins in a Caco-2 gut model
-
Schabacker J., Schwend T., and Wink M. Reduction of acrylamide uptake by dietary proteins in a Caco-2 gut model. J. Agric. Food Chem. 52 (2004) 4021-4025
-
(2004)
J. Agric. Food Chem.
, vol.52
, pp. 4021-4025
-
-
Schabacker, J.1
Schwend, T.2
Wink, M.3
-
38
-
-
0036967047
-
Acrylamide: increased concentrations in homemade food and first evidence of its variable absorption from food, variable metabolism and placental and breast milk transfer in humans
-
Sorgel F., Weissenbacher R., Kinzig-Schippers M., Hofmann A., Illauer M., Skott A., and Landersdorfer C. Acrylamide: increased concentrations in homemade food and first evidence of its variable absorption from food, variable metabolism and placental and breast milk transfer in humans. Chemotherapy 48 (2002) 267-274
-
(2002)
Chemotherapy
, vol.48
, pp. 267-274
-
-
Sorgel, F.1
Weissenbacher, R.2
Kinzig-Schippers, M.3
Hofmann, A.4
Illauer, M.5
Skott, A.6
Landersdorfer, C.7
-
39
-
-
0031974645
-
Validation of a Caco-2 cell monolayer culture for drug transport studies
-
Sulzbacher A., Jarosch A., Schuler R., Acerbi D., Ventura P., Puccini P., and Woodcock B.G. Validation of a Caco-2 cell monolayer culture for drug transport studies. Int. J. Clin. Pharmacol. Ther. 36 (1998) 86-89
-
(1998)
Int. J. Clin. Pharmacol. Ther.
, vol.36
, pp. 86-89
-
-
Sulzbacher, A.1
Jarosch, A.2
Schuler, R.3
Acerbi, D.4
Ventura, P.5
Puccini, P.6
Woodcock, B.G.7
-
40
-
-
0034043150
-
Acrylamide: a cooking carcinogen?
-
Tareke E., Rydberg P., Karlsson P., Eriksson S., and Tornqvist M. Acrylamide: a cooking carcinogen?. Chem. Res. Toxicol. 13 (2000) 517-522
-
(2000)
Chem. Res. Toxicol.
, vol.13
, pp. 517-522
-
-
Tareke, E.1
Rydberg, P.2
Karlsson, P.3
Eriksson, S.4
Tornqvist, M.5
-
41
-
-
0037077394
-
Analysis of acrylamide, a carcinogen formed in heated foodstuffs
-
Tareke E., Rydberg P., Karlsson P., Eriksson S., and Tornqvist M. Analysis of acrylamide, a carcinogen formed in heated foodstuffs. J. Agric. Food Chem. 50 (2002) 4998-5006
-
(2002)
J. Agric. Food Chem.
, vol.50
, pp. 4998-5006
-
-
Tareke, E.1
Rydberg, P.2
Karlsson, P.3
Eriksson, S.4
Tornqvist, M.5
-
42
-
-
0031033341
-
Decreased activity of inducible nitric oxide synthase type 2 and modulation of the expression of glutathione S-transferase alpha, bcl-2, and metallothioneins during the differentiation of Caco-2 cells
-
Vecchini F., Pringault E., Billiar T.R., Geller D.A., Hausel P., and Felley-Bosco E. Decreased activity of inducible nitric oxide synthase type 2 and modulation of the expression of glutathione S-transferase alpha, bcl-2, and metallothioneins during the differentiation of Caco-2 cells. Cell Growth Differ. 8 (1997) 261-268
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 261-268
-
-
Vecchini, F.1
Pringault, E.2
Billiar, T.R.3
Geller, D.A.4
Hausel, P.5
Felley-Bosco, E.6
-
43
-
-
0025663355
-
Oxidants, ATP depletion, and endothelial permeability to macromolecules
-
Wilson J., Winter M., and Shasby D.M. Oxidants, ATP depletion, and endothelial permeability to macromolecules. Blood 76 (1990) 2578-2582
-
(1990)
Blood
, vol.76
, pp. 2578-2582
-
-
Wilson, J.1
Winter, M.2
Shasby, D.M.3
-
44
-
-
0023201142
-
Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct
-
Wong S.H., Knight J.A., Hopfer S.M., Zaharia O., Leach Jr. C.N., and Sunderman Jr. F.W. Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clin. Chem. 33 (1987) 214-220
-
(1987)
Clin. Chem.
, vol.33
, pp. 214-220
-
-
Wong, S.H.1
Knight, J.A.2
Hopfer, S.M.3
Zaharia, O.4
Leach Jr., C.N.5
Sunderman Jr., F.W.6
-
45
-
-
0035941155
-
Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2
-
Yamaguchi H., Yano I., Saito H., and Inui K. Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2. Eur. J. Pharmacol. 431 (2001) 297-303
-
(2001)
Eur. J. Pharmacol.
, vol.431
, pp. 297-303
-
-
Yamaguchi, H.1
Yano, I.2
Saito, H.3
Inui, K.4
-
46
-
-
31044449339
-
Acrylamide-induced oxidative stress and biochemical perturbations in rats
-
Yousef M.I., and El-Demerdash F.M. Acrylamide-induced oxidative stress and biochemical perturbations in rats. Toxicology 219 (2006) 133-141
-
(2006)
Toxicology
, vol.219
, pp. 133-141
-
-
Yousef, M.I.1
El-Demerdash, F.M.2
|