Anticancer nucleobase analogues 6-mercaptopurine and 6-thioguanine are novel substrates for equilibrative nucleoside transporter 2

International Journal of Pharmaceutics

Volumn 333, Issue 1-2, 2007, Pages 56-61

  Nagai, Katsuhito ^a   Nagasawa, Kazuki ^a   Kihara, Yukiko ^a   Okuda, Hiroto ^a   Fujimoto, Sadaki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

6 Thiopurine; Chemotherapy; Nucleobase; Nucleoside; Transporter

Indexed keywords

EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; FLUOROURACIL; HYPOXANTHINE; MERCAPTOPURINE; NUCLEIC ACID BASE; TIOGUANINE;

ANIMAL CELL; ARTICLE; CANCER THERAPY; CELL STRAIN COS7; CONTROLLED STUDY; DNA TRANSFECTION; DRUG PROTEIN BINDING; DRUG TRANSPORT; DRUG UPTAKE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

6-MERCAPTOPURINE; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BINDING, COMPETITIVE; CELL MEMBRANE PERMEABILITY; CERCOPITHECUS AETHIOPS; COS CELLS; EQUILIBRATIVE-NUCLEOSIDE TRANSPORTER 2; FLUOROURACIL; GUANINE; HYPOXANTHINE; KINETICS; MICE; THIOGUANINE; TRANSFECTION; URACIL; URIDINE;

EID: 33847158786     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.09.044     Document Type: Article

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