메뉴 건너뛰기




Volumn 150, Issue 1, 2007, Pages 61-69

Lower levels of whole blood serotonin in obsessive-compulsive disorder and in schizophrenia with obsessive-compulsive symptoms

Author keywords

Clinical characteristic; Clozapine; Obsessive compulsive disorder; Obsessive compulsive symptoms; Schizophrenia; Serotonin

Indexed keywords

CLOZAPINE; SEROTONIN;

EID: 33847153920     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psychres.2005.10.005     Document Type: Article
Times cited : (22)

References (66)
  • 1
    • 0016619644 scopus 로고
    • Effect of clozapine on 5-HIAA excretion in urine and CSF of psychotic patients and on serotonin metabolism in rat brain
    • Ackenheil M., Blatt B., and Lampart C. Effect of clozapine on 5-HIAA excretion in urine and CSF of psychotic patients and on serotonin metabolism in rat brain. Acta Vitaminologica et Enzymologica 29 (1975) 79-84
    • (1975) Acta Vitaminologica et Enzymologica , vol.29 , pp. 79-84
    • Ackenheil, M.1    Blatt, B.2    Lampart, C.3
  • 4
    • 0033020254 scopus 로고    scopus 로고
    • Pharmacoclinical strategy in neuroleptic resistant schizophrenic patients treated by clozapine: clinical evolution, concentration of plasma and red blood cell clozapine and desmethylclozapine, whole blood serotonin and tryptophan
    • Aymard N., Viala A., Baldacci C., Smagghe P.O., Vacheron M.N., and Caroli F. Pharmacoclinical strategy in neuroleptic resistant schizophrenic patients treated by clozapine: clinical evolution, concentration of plasma and red blood cell clozapine and desmethylclozapine, whole blood serotonin and tryptophan. Progress in Neuro-psychopharmacology & Biological Psychiatry 23 (1999) 25-41
    • (1999) Progress in Neuro-psychopharmacology & Biological Psychiatry , vol.23 , pp. 25-41
    • Aymard, N.1    Viala, A.2    Baldacci, C.3    Smagghe, P.O.4    Vacheron, M.N.5    Caroli, F.6
  • 6
    • 0017800466 scopus 로고
    • 5-Hydroxytryptamine content of the whole blood in psychiatric illness and alcoholism
    • Banki C.M. 5-Hydroxytryptamine content of the whole blood in psychiatric illness and alcoholism. Acta Psychiatica Scandinavica 57 (1978) 232-238
    • (1978) Acta Psychiatica Scandinavica , vol.57 , pp. 232-238
    • Banki, C.M.1
  • 7
    • 0017804774 scopus 로고
    • Alterations of cerebrospinal fluid 5-hydroxyindoleacetic acid, and total blood serotonin content during clozapine treatment
    • Banki C.M. Alterations of cerebrospinal fluid 5-hydroxyindoleacetic acid, and total blood serotonin content during clozapine treatment. Psychopharmacology (Berlin) 56 (1978) 195-198
    • (1978) Psychopharmacology (Berlin) , vol.56 , pp. 195-198
    • Banki, C.M.1
  • 11
  • 12
    • 0028855452 scopus 로고
    • Serotonin, schizophrenia and antipsychotic drug action
    • Breier A. Serotonin, schizophrenia and antipsychotic drug action. Schizophrenia Research 14 (1995) 187-202
    • (1995) Schizophrenia Research , vol.14 , pp. 187-202
    • Breier, A.1
  • 13
    • 20444425685 scopus 로고    scopus 로고
    • Obsessive compulsive symptoms in schizophrenia: frequency and clinical features
    • Byerly M., Goodman W., Acholonu W., Bugno R., and Rush A.J. Obsessive compulsive symptoms in schizophrenia: frequency and clinical features. Schizophrenia Research 76 (2005) 309-316
    • (2005) Schizophrenia Research , vol.76 , pp. 309-316
    • Byerly, M.1    Goodman, W.2    Acholonu, W.3    Bugno, R.4    Rush, A.J.5
  • 15
    • 0034936870 scopus 로고    scopus 로고
    • Psychopathology and personality characteristics in relation to blood serotonin in Tourette's syndrome and obsessive-compulsive disorder
    • Cath D.C., Spinhoven P., Landman A.D., and van Kempen G.M. Psychopathology and personality characteristics in relation to blood serotonin in Tourette's syndrome and obsessive-compulsive disorder. Journal of Psychopharmacology 15 (2001) 111-119
    • (2001) Journal of Psychopharmacology , vol.15 , pp. 111-119
    • Cath, D.C.1    Spinhoven, P.2    Landman, A.D.3    van Kempen, G.M.4
  • 17
    • 33847130279 scopus 로고    scopus 로고
    • Platelet serotonin, plasma prolactin and dexa methasone suppression test in patients with obseeive compulsive disorder
    • Chen J., Xiao Z.-p., Lin Z.-g., and Wang K.-x. Platelet serotonin, plasma prolactin and dexa methasone suppression test in patients with obseeive compulsive disorder. Chinese Journal of Psychiatry 37 (2004) 14-17
    • (2004) Chinese Journal of Psychiatry , vol.37 , pp. 14-17
    • Chen, J.1    Xiao, Z.-p.2    Lin, Z.-g.3    Wang, K.-x.4
  • 18
    • 0033000934 scopus 로고    scopus 로고
    • Clozapine and obsessions in patients with recent-onset schizophrenia and other psychotic disorders
    • de Haan L., Linszen D.H., and Gorsira R. Clozapine and obsessions in patients with recent-onset schizophrenia and other psychotic disorders. Journal of Clinical Psychiatry 60 (1999) 364-365
    • (1999) Journal of Clinical Psychiatry , vol.60 , pp. 364-365
    • de Haan, L.1    Linszen, D.H.2    Gorsira, R.3
  • 22
    • 0033758584 scopus 로고    scopus 로고
    • Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study
    • Dursun S.M., Szemis A., Andrews H., Whitaker P., and Reveley M.A. Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study. Journal of Psychiatry and Neuroscience 25 (2000) 347-352
    • (2000) Journal of Psychiatry and Neuroscience , vol.25 , pp. 347-352
    • Dursun, S.M.1    Szemis, A.2    Andrews, H.3    Whitaker, P.4    Reveley, M.A.5
  • 23
    • 0028318243 scopus 로고
    • Exacerbation of obsessive-compulsive symptoms associated with clozapine
    • Eales M.J., and Layeni A.O. Exacerbation of obsessive-compulsive symptoms associated with clozapine. British Journal of Psychiatry 164 (1994) 687-688
    • (1994) British Journal of Psychiatry , vol.164 , pp. 687-688
    • Eales, M.J.1    Layeni, A.O.2
  • 24
    • 0034817280 scopus 로고    scopus 로고
    • Incidence of obsessive-compulsive phenomena in the course of acute schizophrenia and schizoaffective disorder
    • Fabisch K., Fabisch H., Langs G., Huber H.P., and Zapotoczky H.G. Incidence of obsessive-compulsive phenomena in the course of acute schizophrenia and schizoaffective disorder. European Journal of Psychiatry 16 (2001) 336-341
    • (2001) European Journal of Psychiatry , vol.16 , pp. 336-341
    • Fabisch, K.1    Fabisch, H.2    Langs, G.3    Huber, H.P.4    Zapotoczky, H.G.5
  • 27
    • 0016670454 scopus 로고
    • Elevated blood serotonin concentrations in unmedicated chronic schizophrenic patients: a preliminary study
    • Garelis E., Gillin J.C., Wyatt R.J., and Neff N. Elevated blood serotonin concentrations in unmedicated chronic schizophrenic patients: a preliminary study. American Journal of Psychiatry 132 (1975) 184-186
    • (1975) American Journal of Psychiatry , vol.132 , pp. 184-186
    • Garelis, E.1    Gillin, J.C.2    Wyatt, R.J.3    Neff, N.4
  • 28
    • 0024435153 scopus 로고
    • The Yale Brown Obsessive Compulsive Scale (Y-BOCS): Part I. Development, use, and reliability
    • Goodman W., Price H., Rasmussen S., and Blake J.B. The Yale Brown Obsessive Compulsive Scale (Y-BOCS): Part I. Development, use, and reliability. Archives of General Psychiatry 46 (1989) 1006-1011
    • (1989) Archives of General Psychiatry , vol.46 , pp. 1006-1011
    • Goodman, W.1    Price, H.2    Rasmussen, S.3    Blake, J.B.4
  • 30
    • 0025774914 scopus 로고
    • Whole blood serotonin in juvenile obsessive-compulsive disorder
    • Hanna G.L., Yuwiler A., and Cantwell D.P. Whole blood serotonin in juvenile obsessive-compulsive disorder. Biological Psychiatry 29 (1991) 738-744
    • (1991) Biological Psychiatry , vol.29 , pp. 738-744
    • Hanna, G.L.1    Yuwiler, A.2    Cantwell, D.P.3
  • 32
    • 0020563171 scopus 로고
    • Platelet serotonin levels in schizophrenia: relationship to race and psychopathology
    • Jackman H., Luchins D., and Meltzer H.Y. Platelet serotonin levels in schizophrenia: relationship to race and psychopathology. Biological Psychiatry 18 (1983) 887-902
    • (1983) Biological Psychiatry , vol.18 , pp. 887-902
    • Jackman, H.1    Luchins, D.2    Meltzer, H.Y.3
  • 33
    • 0342617825 scopus 로고    scopus 로고
    • Seasonal influence on platelet 5-HT levels in patients with recurrent major depression and schizophrenia
    • Jakovljevic M., Muck-Seler D., Pivac N., Ljubicic D., Bujas M., and Dodig G. Seasonal influence on platelet 5-HT levels in patients with recurrent major depression and schizophrenia. Biological Psychiatry 41 (1997) 1028-1034
    • (1997) Biological Psychiatry , vol.41 , pp. 1028-1034
    • Jakovljevic, M.1    Muck-Seler, D.2    Pivac, N.3    Ljubicic, D.4    Bujas, M.5    Dodig, G.6
  • 34
    • 0017755438 scopus 로고
    • Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and in schizoaffective patients
    • Joseph M.H., Owen F., Baker H.F., and Bourne R.C. Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and in schizoaffective patients. Psychological Medicine 7 (1977) 159-162
    • (1977) Psychological Medicine , vol.7 , pp. 159-162
    • Joseph, M.H.1    Owen, F.2    Baker, H.F.3    Bourne, R.C.4
  • 36
    • 0023128001 scopus 로고
    • Platelet serotonin concentration in schizophrenic patients
    • Kolakowska T., and Molyneux S.G. Platelet serotonin concentration in schizophrenic patients. American Journal of Psychiatry 144 (1987) 232-234
    • (1987) American Journal of Psychiatry , vol.144 , pp. 232-234
    • Kolakowska, T.1    Molyneux, S.G.2
  • 37
    • 0027956611 scopus 로고
    • More on obsessive-compulsive symptoms and clozapine
    • LaPorta L.D. More on obsessive-compulsive symptoms and clozapine. Journal of Clinical Psychiatry 55 (1994) 312
    • (1994) Journal of Clinical Psychiatry , vol.55 , pp. 312
    • LaPorta, L.D.1
  • 38
    • 0027212698 scopus 로고
    • Primary structure of the human platelet serotonin uptake site: identity with the brain serotonin transporter
    • Lesch K.P., Wolozin B.L., Murphy D.L., and Riederer P. Primary structure of the human platelet serotonin uptake site: identity with the brain serotonin transporter. Journal of Neurochemistry 60 (1993) 2319-2322
    • (1993) Journal of Neurochemistry , vol.60 , pp. 2319-2322
    • Lesch, K.P.1    Wolozin, B.L.2    Murphy, D.L.3    Riederer, P.4
  • 39
    • 0026646524 scopus 로고
    • Buspirone induced prolactin responses in obsessive-compulsive disorder (OCD): is OCD a 5-HT2 receptor disorder?
    • Lucey J.V., Butcher G., Clare A.W., and Dinan T.G. Buspirone induced prolactin responses in obsessive-compulsive disorder (OCD): is OCD a 5-HT2 receptor disorder?. International Clinical Psychopharmacology 7 (1992) 45-49
    • (1992) International Clinical Psychopharmacology , vol.7 , pp. 45-49
    • Lucey, J.V.1    Butcher, G.2    Clare, A.W.3    Dinan, T.G.4
  • 41
    • 0026440517 scopus 로고
    • Biogenic amine metabolites in plasma of drug-naive schizophrenic patients: associations with symptomatology
    • Markianos M., Botsis A., and Arvanitis Y. Biogenic amine metabolites in plasma of drug-naive schizophrenic patients: associations with symptomatology. Biological Psychiatry 32 (1992) 288-292
    • (1992) Biological Psychiatry , vol.32 , pp. 288-292
    • Markianos, M.1    Botsis, A.2    Arvanitis, Y.3
  • 42
    • 0036642242 scopus 로고    scopus 로고
    • Prolactin responses to acute clomipramine and haloperidol of male schizophrenic patients in a drug-free state and after treatment with clozapine or with olanzapine
    • Markianos M., Hatzimanolis J., Lykouras L., and Christodoulou G.N. Prolactin responses to acute clomipramine and haloperidol of male schizophrenic patients in a drug-free state and after treatment with clozapine or with olanzapine. Schizophrenia Research 56 (2002) 11-17
    • (2002) Schizophrenia Research , vol.56 , pp. 11-17
    • Markianos, M.1    Hatzimanolis, J.2    Lykouras, L.3    Christodoulou, G.N.4
  • 44
    • 0025744045 scopus 로고
    • Platelet serotonin in subtypes of schizophrenia and unipolar depression
    • Muck-Seler D., Jakovljevic M., and Deanovic Z. Platelet serotonin in subtypes of schizophrenia and unipolar depression. Psychiatry Research 38 (1991) 105-113
    • (1991) Psychiatry Research , vol.38 , pp. 105-113
    • Muck-Seler, D.1    Jakovljevic, M.2    Deanovic, Z.3
  • 45
    • 0029824736 scopus 로고    scopus 로고
    • Effect of age on platelet 5-HT concentrations in healthy controls, depressed and schizophrenic patients
    • Muck-Seler D., Bujas M., Ljubic-Thibal V., and Jakovljevic M. Effect of age on platelet 5-HT concentrations in healthy controls, depressed and schizophrenic patients. Neuropsychobiology 34 (1996) 201-203
    • (1996) Neuropsychobiology , vol.34 , pp. 201-203
    • Muck-Seler, D.1    Bujas, M.2    Ljubic-Thibal, V.3    Jakovljevic, M.4
  • 46
    • 0032891924 scopus 로고    scopus 로고
    • Sex differences, season of birth and platelet 5-HT levels in schizophrenic patients
    • Muck-Seler D., Pivac N., and Jakovljevic M. Sex differences, season of birth and platelet 5-HT levels in schizophrenic patients. Journal of Neural Transmission 106 (1999) 337-347
    • (1999) Journal of Neural Transmission , vol.106 , pp. 337-347
    • Muck-Seler, D.1    Pivac, N.2    Jakovljevic, M.3
  • 47
    • 0345466578 scopus 로고    scopus 로고
    • Platelet serotonin, plasma cortisol, and dexamethasone suppression test in schizophrenic patients
    • Muck-Seler D., Pivac N., Jakovljevic M., and Brzovic Z. Platelet serotonin, plasma cortisol, and dexamethasone suppression test in schizophrenic patients. Biological Psychiatry 45 (1999) 1433-1439
    • (1999) Biological Psychiatry , vol.45 , pp. 1433-1439
    • Muck-Seler, D.1    Pivac, N.2    Jakovljevic, M.3    Brzovic, Z.4
  • 48
    • 3543112049 scopus 로고    scopus 로고
    • Platelet serotonin and plasma prolactin and cortisol in healthy, depressed and schizophrenic women
    • Muck-Seler D., Pivac N., Mustapic M., Crncevic Z., Jakovljevic M., and Sagud M. Platelet serotonin and plasma prolactin and cortisol in healthy, depressed and schizophrenic women. Psychiatry Research 127 (2004) 217-226
    • (2004) Psychiatry Research , vol.127 , pp. 217-226
    • Muck-Seler, D.1    Pivac, N.2    Mustapic, M.3    Crncevic, Z.4    Jakovljevic, M.5    Sagud, M.6
  • 49
    • 0028176783 scopus 로고
    • Monoamine activity reflected in urine of young patients with obsessive compulsive disorder, psychosis with and without reality distortion and healthy subjects: an explorative analysis
    • Oades R.D., Ropcke B., and Eggers C. Monoamine activity reflected in urine of young patients with obsessive compulsive disorder, psychosis with and without reality distortion and healthy subjects: an explorative analysis. Journal of Neural Transmission. General Section 96 (1994) 143-159
    • (1994) Journal of Neural Transmission. General Section , vol.96 , pp. 143-159
    • Oades, R.D.1    Ropcke, B.2    Eggers, C.3
  • 50
    • 0036163728 scopus 로고    scopus 로고
    • Relations of clinical features, subgroups and medication to serum monoamines in schizophrenia
    • Oades R.D., Klimke A., Henning U., and Rao M.L. Relations of clinical features, subgroups and medication to serum monoamines in schizophrenia. Human Psychopharmacology 17 (2002) 15-27
    • (2002) Human Psychopharmacology , vol.17 , pp. 15-27
    • Oades, R.D.1    Klimke, A.2    Henning, U.3    Rao, M.L.4
  • 51
    • 33845214840 scopus 로고    scopus 로고
    • Neuropsychological measures of attention and memory function in schizophrenia: relationships with symptom dimensions and serum monoamine activity
    • Oades R.D., Roepcke B., Henning U., and Klimke A. Neuropsychological measures of attention and memory function in schizophrenia: relationships with symptom dimensions and serum monoamine activity. Behavioral and Brain Functions 1 (2005) 14
    • (2005) Behavioral and Brain Functions , vol.1 , pp. 14
    • Oades, R.D.1    Roepcke, B.2    Henning, U.3    Klimke, A.4
  • 52
    • 18844381122 scopus 로고    scopus 로고
    • Obsessive-compulsive symptoms in schizophrenia: associated clinical features, cognitive function and medication status
    • Ongur D., and Goff D.C. Obsessive-compulsive symptoms in schizophrenia: associated clinical features, cognitive function and medication status. Schizophrenia Research 75 (2005) 349-362
    • (2005) Schizophrenia Research , vol.75 , pp. 349-362
    • Ongur, D.1    Goff, D.C.2
  • 53
    • 0028916905 scopus 로고
    • Efficacy of drug treatment in obsessive-compulsive disorder. A meta-analytic review
    • Piccinelli M., Pini S., Bellantuono C., and Wilkinson G. Efficacy of drug treatment in obsessive-compulsive disorder. A meta-analytic review. British Journal of Psychiatry 166 (1995) 424-443
    • (1995) British Journal of Psychiatry , vol.166 , pp. 424-443
    • Piccinelli, M.1    Pini, S.2    Bellantuono, C.3    Wilkinson, G.4
  • 54
    • 0032722095 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder in patients with first-episode schizophrenia
    • Poyurovsky M., Fuchs C., and Weizman A. Obsessive-compulsive disorder in patients with first-episode schizophrenia. American Journal of Psychiatry 156 (1999) 1998-2000
    • (1999) American Journal of Psychiatry , vol.156 , pp. 1998-2000
    • Poyurovsky, M.1    Fuchs, C.2    Weizman, A.3
  • 56
    • 0344119582 scopus 로고    scopus 로고
    • Comparison of clinical characteristics and comorbidity in schizophrenia patients with and without obsessive-compulsive disorder: schizophrenic and OC symptoms in schizophrenia
    • Poyurovsky M., Kriss V., Weisman G., Faragian S., Kurs R., Schneidman M., Fuchs C., Weizman A., and Weizman R. Comparison of clinical characteristics and comorbidity in schizophrenia patients with and without obsessive-compulsive disorder: schizophrenic and OC symptoms in schizophrenia. Journal of Clinical Psychiatry 64 (2003) 1300-1307
    • (2003) Journal of Clinical Psychiatry , vol.64 , pp. 1300-1307
    • Poyurovsky, M.1    Kriss, V.2    Weisman, G.3    Faragian, S.4    Kurs, R.5    Schneidman, M.6    Fuchs, C.7    Weizman, A.8    Weizman, R.9
  • 57
    • 0035063517 scopus 로고    scopus 로고
    • Obsessive-compulsive disorders in adolescents with diagnosed schizophrenia
    • Rabe-Jablonska J. Obsessive-compulsive disorders in adolescents with diagnosed schizophrenia. Psychiatria Polska 35 (2001) 47-57
    • (2001) Psychiatria Polska , vol.35 , pp. 47-57
    • Rabe-Jablonska, J.1
  • 58
    • 0029889666 scopus 로고    scopus 로고
    • Drug treatment of obsessive-compulsive disorder (OCD): long-term trial with clomipramine and selective serotonin reuptake inhibitors (SSRIs)
    • Ravizza L., Barzega G., Bellino S., Bogetto F., and Maina G. Drug treatment of obsessive-compulsive disorder (OCD): long-term trial with clomipramine and selective serotonin reuptake inhibitors (SSRIs). Psychopharmacology Bulletin 32 (1996) 167-173
    • (1996) Psychopharmacology Bulletin , vol.32 , pp. 167-173
    • Ravizza, L.1    Barzega, G.2    Bellino, S.3    Bogetto, F.4    Maina, G.5
  • 60
    • 0035196311 scopus 로고    scopus 로고
    • The effect of olanzapine treatment on m-chlorophenylpiperazine-induced hormone release in schizophrenia
    • Scheepers F.E., Gespen de Wied C.C., and Kahn R.S. The effect of olanzapine treatment on m-chlorophenylpiperazine-induced hormone release in schizophrenia. Journal of Clinical Psychopharmacology 21 (2001) 575-582
    • (2001) Journal of Clinical Psychopharmacology , vol.21 , pp. 575-582
    • Scheepers, F.E.1    Gespen de Wied, C.C.2    Kahn, R.S.3
  • 61
    • 0029781286 scopus 로고    scopus 로고
    • Correlated changes in symptoms and neurotransmitter indices during maintenance treatment with clozapine or conventional neuroleptics in adolescents and young adults with schizophrenia
    • Schulz E., Fleischhaker C., and Remschmidt H.E. Correlated changes in symptoms and neurotransmitter indices during maintenance treatment with clozapine or conventional neuroleptics in adolescents and young adults with schizophrenia. Journal of Child and Adolescent Psychopharmacology 6 (1996) 119-131
    • (1996) Journal of Child and Adolescent Psychopharmacology , vol.6 , pp. 119-131
    • Schulz, E.1    Fleischhaker, C.2    Remschmidt, H.E.3
  • 65
    • 33847139930 scopus 로고    scopus 로고
    • A comparative study of platelet serotonin in patients with obsessive-compulsive disorder
    • Xiao Z.-p., Zhang M.-d., Wang Z., and Chen Y. A comparative study of platelet serotonin in patients with obsessive-compulsive disorder. Chinical Journal of Psychiatry 36 (2003) 211-214
    • (2003) Chinical Journal of Psychiatry , vol.36 , pp. 211-214
    • Xiao, Z.-p.1    Zhang, M.-d.2    Wang, Z.3    Chen, Y.4
  • 66
    • 0023277098 scopus 로고
    • Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology
    • Zohar J., and Insel T.R. Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology. Biological Psychiatry 22 (1987) 667-687
    • (1987) Biological Psychiatry , vol.22 , pp. 667-687
    • Zohar, J.1    Insel, T.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.