메뉴 건너뛰기




Volumn 23, Issue 1, 1999, Pages 25-41

Pharmacoclinical strategy in neuroleptic resistant schizophrenic patients treated by clozapine: Clinical evolution, concentration of plasma and red blood cell clozapine and desmethylclozapine, whole blood serotonin and tryptophan

Author keywords

Atypical neuroleptic; Clinical correlations; Clozapine; Fluoxetine; Plasma; Red blood cells; Refractory schizophrenia; Serotonin

Indexed keywords

CLOZAPINE; FLUOXETINE; NORCLOZAPINE; NORFLUOXETINE; SEROTONIN; TRYPTOPHAN;

EID: 0033020254     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(98)00089-X     Document Type: Article
Times cited : (10)

References (34)
  • 2
    • 0002639926 scopus 로고
    • Intérêt de la détermination des concentrations intra-érythrocytaires des antidépresseurs tricycliques, tétracycliques et de leurs dérivés déméthylés
    • Compte-rendu du 8ème colloque de Pont à Mousson. John Libbey Eurotext: Paris
    • Aymard, N., Renouard, C., Leyris, A. and Carbuccia, I. (1993) Intérêt de la détermination des concentrations intra-érythrocytaires des antidépresseurs tricycliques, tétracycliques et de leurs dérivés déméthylés. Biologie Prospective. Compte-rendu du 8ème colloque de Pont à Mousson. John Libbey Eurotext: Paris; 191-194.
    • (1993) Biologie Prospective , pp. 191-194
    • Aymard, N.1    Renouard, C.2    Leyris, A.3    Carbuccia, I.4
  • 3
    • 0028084262 scopus 로고
    • Determination of 5- hydroxytryptamine and tryptophan by liquid chromatography in whole blood. Its interest for the exploration of mental disorders
    • Aymard, N., Honore, P. and Carbuccia, I. (1994) Determination of 5- hydroxytryptamine and tryptophan by liquid chromatography in whole blood. Its interest for the exploration of mental disorders. Prog. Neuro-psychopharmacol. & Biol. Psychiat. 18: 77-86.
    • (1994) Prog. Neuro-psychopharmacol. & Biol. Psychiat. , vol.18 , pp. 77-86
    • Aymard, N.1    Honore, P.2    Carbuccia, I.3
  • 4
    • 0029591350 scopus 로고
    • Pharmacoclinical correlations in schizophrenic patients treated with haloperidol decanoate: Clinical evaluations, concentrations of plasma and red blood cell haloperidol and its reduced metabolite, and plasma homovanillic acid
    • Aymard, N., Viala, A., Stein, I. and Caroli, F. (1995) Pharmacoclinical correlations in schizophrenic patients treated with haloperidol decanoate: Clinical evaluations, concentrations of plasma and red blood cell haloperidol and its reduced metabolite, and plasma homovanillic acid. Prog. Neuro-psychopharmacol. & Biol. Psychiat., 19: 1119-1135.
    • (1995) Prog. Neuro-psychopharmacol. & Biol. Psychiat. , vol.19 , pp. 1119-1135
    • Aymard, N.1    Viala, A.2    Stein, I.3    Caroli, F.4
  • 5
    • 0030806843 scopus 로고    scopus 로고
    • Neuroleptic-resistant schizophrenic patients treated by clozapine: Clinical evolution, plasma and red blood cell clozapine and desmethylclozapine levels
    • Aymard, N., Baldacci, C., Leyris, A., Smagghe, P.O., Tribolet, S., Vacheron, M.N., Viala, A. and Caroli, F. (1997) Neuroleptic-resistant schizophrenic patients treated by clozapine: Clinical evolution, plasma and red blood cell clozapine and desmethylclozapine levels. Therapie, 52: 227-232.
    • (1997) Therapie , vol.52 , pp. 227-232
    • Aymard, N.1    Baldacci, C.2    Leyris, A.3    Smagghe, P.O.4    Tribolet, S.5    Vacheron, M.N.6    Viala, A.7    Caroli, F.8
  • 6
    • 0028855452 scopus 로고
    • Serotonin, schizophrenia and antipsychotic drug action
    • Breier, A. (1995) Serotonin, schizophrenia and antipsychotic drug action. Schizophrenia Research, 14: 187-202.
    • (1995) Schizophrenia Research , vol.14 , pp. 187-202
    • Breier, A.1
  • 7
    • 0029583266 scopus 로고
    • Neurocircuities and neurotransmitter interactions in schizophrenia
    • Carlsson, A. (1995) Neurocircuities and neurotransmitter interactions in schizophrenia. Int. Clin. Psychopharmacol., 10: (suppl.3): 21-28.
    • (1995) Int. Clin. Psychopharmacol. , vol.10 , Issue.SUPPL. 3 , pp. 21-28
    • Carlsson, A.1
  • 8
    • 0031439716 scopus 로고    scopus 로고
    • Clinical evaluation and plasma clozapine concentrations in chinese patients with schizophrenia
    • Chong, S.A., Tan, C.H., Khoo, Y.M., Lee, H.S., Wong, K.E., Ngui, F. and Winslow, M. (1997) Clinical evaluation and plasma clozapine concentrations in chinese patients with schizophrenia. Ther. Drug Monit., 19: 219-223.
    • (1997) Ther. Drug Monit. , vol.19 , pp. 219-223
    • Chong, S.A.1    Tan, C.H.2    Khoo, Y.M.3    Lee, H.S.4    Wong, K.E.5    Ngui, F.6    Winslow, M.7
  • 9
    • 0030863262 scopus 로고    scopus 로고
    • Time to clozapine response in a standardized trial
    • Conley, R.R., Carpenter, W.T. and Tamminga, C. (1997) Time to clozapine response in a standardized trial. Am. J; Psychiatry, 154 (9): 1243-1247.
    • (1997) Am. J; Psychiatry , vol.154 , Issue.9 , pp. 1243-1247
    • Conley, R.R.1    Carpenter, W.T.2    Tamminga, C.3
  • 10
    • 0029779848 scopus 로고    scopus 로고
    • Adjunctive antidepressant drug therapies in the treatment of negative symptoms of schizophrenia
    • Evins, A.E. and Goff, D.C. (1996) Adjunctive antidepressant drug therapies in the treatment of negative symptoms of schizophrenia. CNS Drug, 2: 130-147.
    • (1996) CNS Drug , vol.2 , pp. 130-147
    • Evins, A.E.1    Goff, D.C.2
  • 11
    • 0031048241 scopus 로고    scopus 로고
    • Will routine therapeutic drug monitoring have a place in clozapine therapy?
    • Freeman, D.J. and Oyewumi, K. (1997) Will routine therapeutic drug monitoring have a place in clozapine therapy? Clin. Pharmacokinet., 32 (2): 93-100.
    • (1997) Clin. Pharmacokinet. , vol.32 , Issue.2 , pp. 93-100
    • Freeman, D.J.1    Oyewumi, K.2
  • 12
    • 0013570955 scopus 로고
    • Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: Effect of smoking
    • Hasegawa, M., Gutierrez-Esteinou, R., Way, L. and Meltzer, H.Y. (1993) Relationship between clinical efficacy and clozapine concentrations in plasma in schizophrenia: Effect of smoking. Psychopharmacology (Berl), 10: 799-812.
    • (1993) Psychopharmacology (Berl) , vol.10 , pp. 799-812
    • Hasegawa, M.1    Gutierrez-Esteinou, R.2    Way, L.3    Meltzer, H.Y.4
  • 13
    • 0027968894 scopus 로고
    • Plasma clozapine and desmethylclozapine levels in clozapine-induced agranulocytosis
    • Hasegawa, M., Cola, P.A. and Meltzer, H.Y. (1994) Plasma clozapine and desmethylclozapine levels in clozapine-induced agranulocytosis. Neuropsychopharmacology, 11(n°1): 45-47.
    • (1994) Neuropsychopharmacology , vol.11 , Issue.N01 , pp. 45-47
    • Hasegawa, M.1    Cola, P.A.2    Meltzer, H.Y.3
  • 14
    • 0021154534 scopus 로고
    • The quality of life scale: An instrument for rating the schizophrenic deficit syndrome
    • Heinrich, C.W., Hanlon, T.E. and Carpenter, W.T. (1984) The quality of life scale: An instrument for rating the schizophrenic deficit syndrome. Schizophrenia Bull., 3: 388-396.
    • (1984) Schizophrenia Bull. , vol.3 , pp. 388-396
    • Heinrich, C.W.1    Hanlon, T.E.2    Carpenter, W.T.3
  • 15
    • 0029620775 scopus 로고
    • The role of serotonin in schizophrenia
    • Iqbal, N. and Van Praag, G. (1995) The role of serotonin in schizophrenia. Eur. Neuropsychopharmacol., suppl.: 11-23.
    • (1995) Eur. Neuropsychopharmacol. , Issue.SUPPL. , pp. 11-23
    • Iqbal, N.1    Van Praag, G.2
  • 16
    • 0030887062 scopus 로고    scopus 로고
    • The use of scales for clinical monitoring of disease progression and the treatment of schizophrenia
    • Kane, J.M. (1997) The use of scales for clinical monitoring of disease progression and the treatment of schizophrenia. Neuropsychobiology, 35: 64-66.
    • (1997) Neuropsychobiology , vol.35 , pp. 64-66
    • Kane, J.M.1
  • 17
    • 0029988896 scopus 로고    scopus 로고
    • Serotonin-dopamine interaction and its relevance to schizophrenia
    • Kapur, S. and Remington, G. (1996) Serotonin-dopamine interaction and its relevance to schizophrenia. Am. J. Psychiatry, 153 (4): 466-476.
    • (1996) Am. J. Psychiatry , vol.153 , Issue.4 , pp. 466-476
    • Kapur, S.1    Remington, G.2
  • 18
    • 0024312571 scopus 로고
    • Haloperidol and reduced haloperidol concentrations in plasma and red blood cells from schizophrenic patients
    • Ko, G.N., Korpi, E.R. and Kirch, D.G. (1989) Haloperidol and reduced haloperidol concentrations in plasma and red blood cells from schizophrenic patients. J. Clin. Psychopharmacol., 9: 186-190.
    • (1989) J. Clin. Psychopharmacol. , vol.9 , pp. 186-190
    • Ko, G.N.1    Korpi, E.R.2    Kirch, D.G.3
  • 19
    • 0028877764 scopus 로고
    • Plasma clozapine levels and clinical response for treatment refractory schizophrenic patients
    • Kronig, M.H., Munne, R.A. and Szymanski, S. (1995) Plasma clozapine levels and clinical response for treatment refractory schizophrenic patients. Am. J. Psychiatry, 152: 799-812.
    • (1995) Am. J. Psychiatry , vol.152 , pp. 799-812
    • Kronig, M.H.1    Munne, R.A.2    Szymanski, S.3
  • 20
    • 0027437017 scopus 로고
    • Selective abnormalities of prefrontal serotonergic receptors in schizophrenia
    • Laruelle, M., Abi-Dargham, A., Casanova, M.F. and Toti, R. (1993) Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. Arch. Gen. Psychiatry, 50: 810-818.
    • (1993) Arch. Gen. Psychiatry , vol.50 , pp. 810-818
    • Laruelle, M.1    Abi-Dargham, A.2    Casanova, M.F.3    Toti, R.4
  • 21
    • 0028270373 scopus 로고
    • Disposition of clozapine and desmethylclozapine in schizophrenic patients
    • Lin, S.K., Chang, W.H., Chung, M.C., Lam, Y.W.F. and Jann, M.W. (1994) Disposition of clozapine and desmethylclozapine in schizophrenic patients. J. Clin. Pharmacol., 34: 318-324.
    • (1994) J. Clin. Pharmacol. , vol.34 , pp. 318-324
    • Lin, S.K.1    Chang, W.H.2    Chung, M.C.3    Lam, Y.W.F.4    Jann, M.W.5
  • 23
    • 0003292607 scopus 로고
    • Role of erythrocytes in the early phase of drug distribution; an element of chronopharmacology?
    • Dreifuss F., Meinardi H.S.,eds. New York: Raven Press Ltd
    • Meijer, J.W.A. and Driessen, O. (1990) Role of erythrocytes in the early phase of drug distribution; an element of chronopharmacology? in: Dreifuss F., Meinardi H.S.,eds. Chronopharmacology in Therapy of the Epilepsies. New York: Raven Press Ltd.
    • (1990) Chronopharmacology in Therapy of the Epilepsies
    • Meijer, J.W.A.1    Driessen, O.2
  • 24
    • 0026537892 scopus 로고
    • Clinical management of clozapine patients in relation to efficacy and side effects
    • Naber, D., Holzbach R,., Perro, C. and Hippius, H. (1992) Clinical management of clozapine patients in relation to efficacy and side effects. Br. J. Psychiatry, 160 (suppl. 17): 54-59.
    • (1992) Br. J. Psychiatry , vol.160 , Issue.SUPPL. 17 , pp. 54-59
    • Naber, D.1    Holzbach, R.2    Perro, C.3    Hippius, H.4
  • 26
    • 0028897012 scopus 로고
    • Clozapine serum levels and side effects during steady state treatment of schizophrenic patients: A cross sectional study
    • Olesen, O.V., Thomsen, K. and Jensen, P.N. (1995) Clozapine serum levels and side effects during steady state treatment of schizophrenic patients: A cross sectional study. Psychopharmacology, 117: 871-878.
    • (1995) Psychopharmacology , vol.117 , pp. 871-878
    • Olesen, O.V.1    Thomsen, K.2    Jensen, P.N.3
  • 27
    • 0028345705 scopus 로고
    • Clozapine treatment in denmark: Concomittant psychotropic medication and hematologic monitoring in a system with liberal usage pratices
    • Peacock, L. and Gerlach, J. (1994) Clozapine treatment in denmark: Concomittant psychotropic medication and hematologic monitoring in a system with liberal usage pratices. J. Clin. Psychiatry, 55: 44-49.
    • (1994) J. Clin. Psychiatry , vol.55 , pp. 44-49
    • Peacock, L.1    Gerlach, J.2
  • 28
    • 0026068791 scopus 로고
    • Clozapine and norclozapine plasma concentrations and clinical response of treatment refractory schizophrenic patients
    • Perry, P.J., Miller, D.D., Arndt, S.V. and Cadoret, R.J. (1991) Clozapine and norclozapine plasma concentrations and clinical response of treatment refractory schizophrenic patients. Am. J. Psychiatry, 148: 231-235.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 231-235
    • Perry, P.J.1    Miller, D.D.2    Arndt, S.V.3    Cadoret, R.J.4
  • 29
    • 0028919572 scopus 로고
    • Prospects for pharmacotherapy of schizophrenia
    • Pickar, D. (1995) Prospects for pharmacotherapy of schizophrenia. The Lancet, 345 (8949): 557-562.
    • (1995) The Lancet , vol.345 , Issue.8949 , pp. 557-562
    • Pickar, D.1
  • 30
    • 0030738648 scopus 로고    scopus 로고
    • Efficacy and side-effects of clozapine not associated with variation in the 5-HT2C receptor
    • Rietschel, M., Naber, D., Fimmers, R., Möller, H.J., Propping, P. and Nöthen, M.M. (1997) Efficacy and side-effects of clozapine not associated with variation in the 5-HT2C receptor. NeuroReport, 8: 1999-2003.
    • (1997) NeuroReport , vol.8 , pp. 1999-2003
    • Rietschel, M.1    Naber, D.2    Fimmers, R.3    Möller, H.J.4    Propping, P.5    Nöthen, M.M.6
  • 31
    • 0031435394 scopus 로고    scopus 로고
    • Blood biogenic amines during clozapine treatment of early-onset schizophrenia
    • Shulz, E., Fleischhaker, C., Clement, H.W. and Remschmidt, H. (1997) Blood biogenic amines during clozapine treatment of early-onset schizophrenia. J. Neural Transm., 104: 1077-1089.
    • (1997) J. Neural Transm. , vol.104 , pp. 1077-1089
    • Shulz, E.1    Fleischhaker, C.2    Clement, H.W.3    Remschmidt, H.4
  • 32
    • 0030903754 scopus 로고    scopus 로고
    • Prediction of short-term changes in symptom severity by baseline plasma homovanillic acid levels in schizophrenic patients receiving clozapine
    • Sumiyoshi, T., Hasegawa, M., Jayathilake, K. and Meltzer, H.Y. (1997) Prediction of short-term changes in symptom severity by baseline plasma homovanillic acid levels in schizophrenic patients receiving clozapine. Psychiat. Res., 69: 113-121
    • (1997) Psychiat. Res. , vol.69 , pp. 113-121
    • Sumiyoshi, T.1    Hasegawa, M.2    Jayathilake, K.3    Meltzer, H.Y.4
  • 33
    • 0026463749 scopus 로고
    • Sensitive micromethod for column liquid chromatographie determination of fluoxetine and norfluoxetine in human plasma
    • Thomare, P., Wang, K. and Van der Meersch, V. (1992) Sensitive micromethod for column liquid chromatographie determination of fluoxetine and norfluoxetine in human plasma. J. Chromatogr., 583: 217-221.
    • (1992) J. Chromatogr. , vol.583 , pp. 217-221
    • Thomare, P.1    Wang, K.2    Van Der Meersch, V.3
  • 34
    • 0025058413 scopus 로고
    • Liquid chromatographic determination of reduced haloperidol and haloperidol concentrations in packed red blood cells from humans
    • Vatassery, G.T., Herzan, L.A. and Kysken, M.W. (1990) Liquid chromatographic determination of reduced haloperidol and haloperidol concentrations in packed red blood cells from humans. J. Anal. Toxicol. 14: 25-27.
    • (1990) J. Anal. Toxicol. , vol.14 , pp. 25-27
    • Vatassery, G.T.1    Herzan, L.A.2    Kysken, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.