Advantages of voltage-gated ion channels as drug targets

Expert Opinion on Therapeutic Targets

Volumn 11, Issue 3, 2007, Pages 265-271

  McGivern, Joseph G ^a  

^a AMGEN INC   (United States)

Author keywords

Auxiliary subunit; Drug discovery; High throughput screening; Pore forming subunit; Target validation; Voltage gated ion channel

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; 3 (5 CHLORO 2 METHOXYPHENYL) 3 FLUORO 2,3 DIHYDRO 6 TRIFLUOROMETHYL 1H INDOL 2 ONE; 4 AMINOPYRIDINE; CARBAMAZEPINE; CELL PROTEIN; CLOTRIMAZOLE; DILTIAZEM; DOFETILIDE; ETHOSUXIMIDE; FLECAINIDE; FLUNARIZINE; FLUOXETINE; GABAPENTIN; ION CHANNEL; LAMOTRIGINE; LIDOCAINE; LINOPIRDINE; MEXILETINE; NICARDIPINE; OMEGA CONOTOXIN MVIIA; PHENYTOIN; PREGABALIN; RETIGABINE; SODIUM CHANNEL BLOCKING AGENT; UNINDEXED DRUG; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL; ZONISAMIDE;

CHANNEL GATING; CRYSTAL STRUCTURE; DRUG EFFICACY; DRUG RESEARCH; DRUG SAFETY; DRUG SCREENING; DRUG SELECTIVITY; DRUG TARGETING; EDITORIAL; HIGH THROUGHPUT SCREENING; HUMAN; IN VIVO STUDY; MOLECULAR CLONING; NONHUMAN; PATCH CLAMP; PREDICTION; PROTEIN ANALYSIS; PROTEIN FUNCTION; SEQUENCE ANALYSIS; VALIDATION STUDY;

ANIMALS; DRUG DESIGN; DRUG THERAPY; HUMANS; ION CHANNEL GATING; ION CHANNELS;

EID: 33847152156     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.11.3.265     Document Type: Editorial

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