The lipoprotein/lipid profile is modulated by a gene-diet interaction effect between polymorphisms in the liver X receptor-α and dietary cholesterol intake in French-Canadians

British Journal of Nutrition

Volumn 97, Issue 1, 2007, Pages 11-18

  Robitaille, Julie ^a,b,c   Houde, Alain ^a   Lemieux, Simone ^b,c   Gaudet, Daniel ^d   Pérusse, Louis ^a,c   Vohl, Marie Claude ^a,b,c  

^a LAVAL UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cardiovascular disease; Dietary cholesterol intake; Gene diet interactions; Liver X receptor ; Plasma lipoprotein lipid profile

Indexed keywords

CHOLESTEROL; LIPID; LIPOPROTEIN; LIVER X RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; CELL RECEPTOR; DNA BINDING PROTEIN; LIVER X RECEPTOR;

ARTICLE; CANADA; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DETERMINATION; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HYPERCHOLESTEROLEMIA; LIPID ANALYSIS; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS; VARIANCE; ADULT; AGE; ALLELE; BAYES THEOREM; BLOOD; CALORIC INTAKE; CAUCASIAN; ETHNOLOGY; FRANCE; GENETICS; LIVER; METABOLISM; MIDDLE AGED; PROMOTER REGION; SEX DIFFERENCE;

ADULT; AGE FACTORS; ALLELES; BAYES THEOREM; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; DNA-BINDING PROTEINS; ENERGY INTAKE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FRANCE; GENE FREQUENCY; HETEROZYGOTE; HUMANS; HYPERCHOLESTEROLEMIA; LIPIDS; LIPOPROTEINS; LIVER; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); QUEBEC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEX FACTORS;

EID: 33847125358     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507201722     Document Type: Article

References (36)

1. Alberti KG & Zimmet PZ (1998). Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO Consultation. Diabet Med 15, 539-553.
2. Boer JM, Kuivenhoven JA, Feskens EJ, Schouten EG, Havekes LM, Seidell JC, Kastelein JJ & Kromhout D (1999) Physical activity modulates the effect of a lipoprotein lipase mutation (D9N) on plasma lipids and lipoproteins. Clin Genet 56, 158-163.
3. Bruce MJ & Katzmarzyk PT (2002) Canadian population trends in leisure-time physical activity levels, 1981-1998. Can J Appl Physiol 27, 681-690.
4. Burstein M & Samaille J (1960) Sur un dosage rapide du cholesterol lié aux alpha et aux bêta lipoprotéines du sérum. Clin Chem Acta 5, 309.
5. Chiang JY, Kimmel R & Stroup D (2001) Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha). Gene 262, 257-265.
6. Clarke R, Frost C, Collins R, Appleby P & Peto R (1997) Dietary lipids and blood cholesterol: Quantitative meta-analysis of metabolic ward studies. BMJ 314, 112-117.
7. Dayton S, Pearce ML, Goldman H, Harnish A, Plotkin D, Shickman M, Winfield M, Zager A & Dixon W (1968) Controlled trial of a diet high in unsaturated fat for prevention of atherosclerotic complications. Lancet 2, 1060-1062.
8. Dreon DM & Krauss RM (1997) Diet-gene interactions in human lipoprotein metabolism. J Am Coll Nutr 16, 313-324.
9. Friedewald WT, Levy RI & Frederickson DS (1972) Estimation of the concentration of Low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18, 499-502.
10. Grundy SM (1995) Role of low-density lipoproteins in atherogenesis and development of coronary heart disease. Clin Chem 41, 139-146.
11. Grundy SM & Denke MA (1990) Dietary influences on serum lipids and lipoproteins. J Lipid Res 31, 1149-1172.
12. Havel RJ, Eder HA & Bragdon JH (1955) The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34, 1345-1354.
13. Heart and Stroke Foundation of Canada (2003) The Growing Burden of Heart Disease and Stroke in Canada 2003. Ottawa, Canada.
14. Hopkins PN (1992) Effects of dietary cholesterol on serum cholesterol: A meta-analysis and review. Am J Clin Nutr 55, 1060-1070.
15. Jacobs DRJ, Anderson JT, Hannan P, Keys A & Blackburn H (1983) Variability in individual serum cholesterol response to change in diet. Arteriosclerosis 3, 349-356.
16. Jakel H, Nowak M, Moitrot E, Dehondt H, Hum DW, Pennacchio LA, Fruchart-Najib J & Fruchart JC (2004) The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c. J Biol Chem 279, 45462-45469.
17. Janowski BA, Willy PJ, Devi TR, Falck JR & Mangelsdorf DJ (1996) An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383, 728-731.
18. Kohro T, Nakajima T, Wada Y, et al. (2000) Genomic structure and mapping of human orphan receptor LXR alpha: Upregulation of LXRa MRNA during monocyte to macrophage differentiation. J Atheroscler Thromb 7, 145-151.
19. Laffitte BA, Joseph SB, Walczak R, Pei L, Wilpitz DC, Collins JL & Tontonoz P (2001) Autoregulation of the human liver X receptor alpha promoter. Mol Cell Biol 21, 7558-7568.
20. Laurell CB (1966) Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal Biochem 15, 42.
21. Lehmann JM, Kliewer SA, Moore LB, et al. (1997) Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J Biol Chem 272, 3137-3140.
22. McNamara JR & Schaefer EJ (1987) Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions. Clin Chim Acta 166, 1-8.
23. Menke JG, Macnaul KL, Hayes NS, et al. (2002) A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a). Endocrinology 143, 2548-2558.
24. Moorjani S, Dupont A, Labrie F, Lupien PJ, Brun D, Gagné C, Giguère M & Bélanger A (1987) Increase in plasma high-density lipoprotein concentration following complete androgen blockage in men with prostatic carcinoma. Metabolism 36, 244-250.
25. Novak K (1998) Cardiovascular disease increasing in developing countries. Nat Med 4, 989-990.
26. Ordovas JM & Schaefer EJ (1999) Genes, variation of cholesterol and fat intake and serum lipids. Curr Opin Lipidol 10, 15-22.
27. Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE & Mangelsdorf DJ (1998) Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 93, 693-704.
28. Rozen S & Skaletsky HJ (2000) Primer 3 on the WWW for general users and for biologist programmers. In Bioinformatics Methods and Protocols: Methods in Molecular Biology, pp. 365-386 [S Krawetz, S Misener editors]. Totowa, NJ: Humana Press.
29. Sarkkinen E, Korhonen M, Erkkila A, Ebeling T & Uusitupa M (1998) Effect of apolipoprotein E polymorphism on serum lipid response to the separate modification of dietary fat and dietary cholesterol [see comments]. Am J Clin Nutr 68, 1215-1222.
30. Stephens M, Smith NJ & Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68, 978-989.
31. Taimela S, Lehtimaki T, Porkka KV, Rasanen L & Viikari JS (1996) The effect of physical activity on serum total and low-density lipoprotein cholesterol concentrations varies with apolipoprotein E phenotype in male children and young adults: The cardiovascular risk in young Finns study. Metabolism 45, 797-803.
32. Tobin KA, Steineger HH, Alberti S, Spydevold O, Auwerx J, Gustafsson JA & Nebb HI (2000) Cross-talk Between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. Mol Endocrinol 14, 741-752.
33. Turpeinen O (1979) Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes. Circulation 59, 1-7.
34. Willett WC, Reynolds RD, Cottrell-Hoehner S, Sàmpson L & Browne ML (1987) Validation of a semi-quantitative food frequency questionnaire: comparison with a 1-year diet record. J Am Diet Assoc 87, 43-47.
35. Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA & Mangelsdorf DJ (1995) LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev 9, 1033-1045.
36. Wilson PW, Garrison RJ, Castelli WP, Feinleib M, McNamara PM & Kannel WB (1980) Prevalence of coronary heart disease in the Framingham Offspring Study: Role of lipoprotein cholesterols. Am J Cardiol 46, 649-654.