Trifluoperazine protects brain plasma membrane Ca2+-ATPase from oxidative damaging

Experimental Brain Research

Volumn 177, Issue 3, 2007, Pages 347-357

  Santos, Patricia Souza Dos ^a   Saraiva, Dayvison Francis ^a   Costa, Danielly Cristiny Ferraz Da ^a   Scofano, Helena Maria ^a   De Carvalho Alves, Paulo Cesar ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antioxidant; ATPase; Brain; Ca2+ signaling; Oxidative stress; Phenothiazine

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ANTIOXIDANT; BUTYLCRESOL; CYSTEINE; DITHIOTHREITOL; FERROUS ASCORBATE; HYDROGEN PEROXIDE; NEUROLEPTIC AGENT; TRIFLUOPERAZINE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CELL; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; LIPID PEROXIDATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

ANIMALS; ANTIOXIDANTS; ANTIPSYCHOTIC AGENTS; BRAIN; BUTYLATED HYDROXYTOLUENE; CELL MEMBRANE; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FERRIC COMPOUNDS; LIPID PEROXIDATION; OXIDATIVE STRESS; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TRIFLUOPERAZINE;

EID: 33847097837     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-006-0678-1     Document Type: Article

References (71)

1. Arundine M, Tymianski M (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 34:325-337
2. Aslan M, Ozben T (2004) Reactive oxygen and nitrogen species in Alzheimer's disease. Curr Alzheimer Res 1:111-119
3. Baba-Aissa F, Raeymaekers L, Wuytack F, Dode L, Casteels R (1998) Distribution and isoform diversity of the organellar Ca2+ pumps in the brain. Mol Chem Neuropathol 33:199-208
4. Bigelow DJ, Squier TC (2005) Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins. Biochim Biophys Acta 1703:121-134
5. Blanchard BJ, Konopka G, Russell M, Ingram VM (1997) Mechanism and prevention of neurotoxicity caused by beta-amyloid peptides: relation to Alzheimer's disease. Brain Res 776:40-50
6. Carafoli E (2004) Calcium-mediated cellular signals: a story of failures. Trends Biochem Sci 29:371-379
7. Carafoli E (2002) Calcium signaling: a tale for all seasons. Proc Natl Acad Sci USA 99:1115-1122
8. Castilho RF, Carvalho-Alves PC, Vercesi AE, Ferreira ST (1996) Oxidative damage to sarcoplasmic reticulum Ca(2+)-pump induced by Fe2+/H2O2/ascorbate is not mediated by lipid peroxidation or thiol oxidation and leads to protein fragmentation. Mol Cell Biochem 159:105-114
9. Chan SL, Fu W, Zhang P, Cheng A, Lee J, Kokame K, Mattson MP (2004) Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress. J Biol Chem 279:28733-28743
10. DeLorenzo RJ, Sun DA, Deshpande LS (2005) Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintainance of epilepsy. Pharmacol Ther 105:229-266
11. Emerit J, Edeas M, Bricaire F (2004) Neurodegenerative diseases and oxidative stress. Biomed Pharmacother 58:39-46
12. Engelender S, De Meis L (1996) Pharmacological differentiation between intracellular calcium pump isoforms. Mol Pharmacol 50:1243-1252
13. Fabiato A, Fabiato F (1979) Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J Physiol (Paris) 75:463-505
14. Feinberg AP, Snyder SH (1975) Phenothiazine drugs: structure-activity relationships explained by a conformation that mimics dopamine. Proc Natl Acad Sci USA 72:1899-1903
15. Fitzjohn SM, Collingridge GL (2002) Calcium stores and synaptic plasticity. Cell Calcium 32:405-411
16. Ganitkevich VY (2003) The role of mitochondria in cytoplasmic Ca2+ cycling. Exp Physiol 88:91-97
17. Grover AK, Kwan CY, Samson SE (2003) Effects of peroxynitrite on sarco/endoplasmic reticulum Ca2+ pump isoforms SERCA2b and SERCA3a. Am J Physiol Cell Physiol 285:C1537-C1543
18. Grover AK, Samson SE, Misquitta CM (1997) Sarco(endo)plasmic reticulum Ca2+ pump isoform SERCA3 is more resistant than SERCA2b to peroxide. Am J Physiol 273:C420-C425
19. Grubmeyer C, Penefsky HS (1981) The presence of two hydrolytic sites on beef heart mitochondrial adenosine triphosphatase. J Biol Chem 256:3718-3727
20. Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP (1997) Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. J Neurosci 17:4212-4222
21. Hakim G, Itano T, Verma AK, Penniston JT (1982) Purification of the Ca2+-and Mg2+-requiring ATPase from rat brain synaptic plasma membrane. Biochem J 207:225-231
22. Halliwell B, Gutteridge JM (1986) Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. Arch Biochem Biophys 246:501-514
23. Kahlert S, Zundorf G, Reiser G (2005) Glutamate-mediated influx of extracellular Ca2+ is coupled with reactive oxygen species generation in cultured hippocampal neurons but not in astrocytes. J Neurosci Res 79:262-271
24. Kaplan P, Babusikova E, Lehotsky J, Dobrota D (2003) Free radical-induced protein modification and inhibition of Ca2+-ATPase of cardiac sarcoplasmic reticulum. Mol Cell Biochem 248:41-47
25. Kaplan P, Doval M, Majerova Z, Lehotsky J, Racay P (2000) Iron-induced lipid peroxidation and protein modification in endoplasmic reticulum membranes. Protection by stobadine. Int J Biochem Cell Biol 32:539-547
26. Khan SZ, Longland CL, Michelangeli F (2000) The effects of phenothiazines and other calmodulin antagonists on the sarcoplasmic and endoplasmic reticulum Ca(2+) pumps. Biochem Pharmacol 60:1797-1806
27. Kristian T, Siesjo BK (1998) Calcium in ischemic cell death. Stroke 29:705-718
28. Lehotsky J, Kaplan P, Babusikova E, Strapkova A, Murin R (2003) Molecular pathways of endoplasmic reticulum dysfunctions: possible cause of cell death in the nervous system. Physiol Res 52:269-274
29. Lehotsky J, Kaplan P, Matejovicova M, Murin R, Racay P, Raeymaekers L (2002) Ion transport systems as targets of free radicals during ischemia reperfusion injury. Gen Physiol Biophys 21:31-37
30. Lencesova L, O'Neill A, Resneck WG, Bloch RJ, Blaustein MP (2004) Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes. J Biol Chem 279:2885-2893
31. Lipton P (1999) Ischemic cell death in brain neurons. Physiol Rev 79:1431-1568
32. Love S, Barber R, Wilcock GK (2000) Neuronal death in brain infarcts in man. Neuropathol Appl Neurobiol 26:55-66
33. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
34. Maccioni RB, Munoz JP, Barbeito L (2001) The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch Med Res 32:367-381
35. Maia JCC, Gomes SL, Juliani MH (1983) In: Morel CM (Ed) Genes and antigens of parasites - a laboratory manual proceedings, FIOCRUZ, Rio de Janeiro, pp 144-157
36. Mattson MP, Barger SW, Begley JG, Mark RJ (1995) Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol 46:187-216
37. Mattson MP, Chan SL (2003) Neuronal and glial calcium signaling in Alzheimer's disease. Cell Calcium 34:385-397
38. Mattson MP, Duan W, Pedersen WA, Culmsee C (2001a) Neurodegenerative disorders and ischemic brain diseases. Apoptosis 6:69-81
39. Mattson MP, Gary DS, Chan SL, Duan W (2001b) Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease. Biochem Soc Symp151-162
40. McConnell EJ, Bittelmeyer AM, Raess BU (1999) Irreversible inhibition of plasma membrane (Ca2+ + Mg2+)-ATPase and Ca2+ transport by 4-OH-2,3-trans- nonenal. Arch Biochem Biophys 361:252-256
41. Moreau VH, Castilho RF, Ferreira ST, Carvalho-Alves PC (1998) Oxidative damage to sarcoplasmic reticulum Ca2+-ATPase AT submicromolar iron concentrations: evidence for metal-catalyzed oxidation. Free Radic Biol Med 25:554-560
42. O'Shaughnessy TJ, Yan H, Kim J, Middlekauff EH, Lee KW, Phillips LH, Kim J, Kim YI (1998) Amyotrophic lateral sclerosis: serum factors enhance spontaneous and evoked transmitter release at the neuromuscular junction. Muscle Nerve 21:81-90
43. Pan G, Zhou T, Radding W, Saag MS, Mountz JD, McDonald JM (1998) Calmodulin antagonists inhibit apoptosis of CD4+ T-cells from patients with AIDS. Immunopharmacology 40:91-103
44. Paschen W (2003a) Mechanisms of neuronal cell death: diverse roles of calcium in the various subcellular compartments. Cell Calcium 34:305-310
45. Paschen W (2003b) Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34:365-383
46. Pereira C, Ferreira C, Carvalho C, Oliveira C (1996) Contribution of plasma membrane and endoplasmic reticulum Ca(2+)-ATPases to the synaptosomal [Ca2+]i increase during oxidative stress. Brain Res 713:269-277
47. Pereira RS, Bertocchi AP, Vercesi AE (1992) Protective effect of trifluoperazine on the mitochondrial damage induced by Ca2+ plus prooxidants. Biochem Pharmacol 44:1795-1801
48. Petersen OH, Michalak M, Verkhratsky A (2005) Calcium signalling: past, present and future. Cell Calcium 38:161-169
49. Phillis JW, Diaz FG, O'Regan MH, Pilitsis JG (2002) Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex. Brain Res 957:12-24
50. Prolla TA, Mattson MP (2001) Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction. Trends Neurosci 24:S21-S31
51. Racay P, Bezakova G, Kaplan P, Lehotsky J, Mezesova V (1994) Alteration in rabbit brain endoplasmic reticulum Ca2+ transport by free oxygen radicals in vitro. Biochem Biophys Res Commun 199:63-69
52. Rao RV, Castro-Obregon S, Frankowski H, Schuler M, Stoka V, del RG, Bredesen DE, Ellerby HM (2002) Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem 277:21836-21842
53. Sattler R, Tymianski M (2000) Molecular mechanisms of calcium-dependent excitotoxicity. J Mol Med 78:3-13
54. Schroder M, Kaufman RJ (2005) ER stress and the unfolded protein response. Mutat Res 569:29-63
55. Shaw PJ, Ince PG (1997) Glutamate, excitotoxicity and amyotrophic lateral sclerosis. J Neurol 244(Suppl 2):S3-14
56. Siems W, Capuozzo E, Lucano A, Salerno C, Crifo C (2003) High sensitivity of plasma membrane ion transport ATPases from human neutrophils towards 4-hydroxy-2,3-trans-nonenal. Life Sci 73:2583-2590
57. Squier TC (2001) Oxidative stress and protein aggregation during biological aging. Exp Gerontol 36:1539-1550
58. Squier TC, Bigelow DJ (2000) Protein oxidation and age-dependent alterations in calcium homeostasis. Front Biosci 5:D504-D526
59. Stadtman ER (1993) Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions. Annu Rev Biochem 62:797-821
60. Supattapone S, Danoff SK, Theibert A, Joseph SK, Steiner J, Snyder SH (1988) Cyclic AMP-dependent phosphorylation of a brain inositol trisphosphate receptor decreases its release of calcium. Proc Natl Acad Sci USA 85:8747-8750
61. Toescu EC, Verkhratsky A (2003) Neuronal ageing from an intraneuronal perspective: roles of endoplasmic reticulum and mitochondria. Cell Calcium 34:311-323
62. Toescu EC, Verkhratsky A (2004) Ca2+ and mitochondria as substrates for deficits in synaptic plasticity in normal brain ageing. J Cell Mol Med 8:181-190
63. Verkhratsky A, Toescu EC (2003) Endoplasmic reticulum Ca(2+) homeostasis and neuronal death. J Cell Mol Med 7:351-361
64. Viner RI, Ferrington DA, Williams TD, Bigelow DJ, Schoneich C (1999a) Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle. Biochem J 340(Pt 3):657-669
65. Viner RI, Williams TD, Schoneich C (1999b) Peroxynitrite modification of protein thiols: oxidation, nitrosylation, and S-glutathiolation of functionally important cysteine residue(s) in the sarcoplasmic reticulum Ca-ATPase. Biochemistry 38:12408-12415
66. Viner RI, Williams TD, Schoneich C (2000) Nitric oxide-dependent modification of the sarcoplasmic reticulum Ca-ATPase: localization of cysteine target sites. Free Radic Biol Med 29:489-496
67. Walseth TF, Johnson RA (1979) The enzymatic preparation of [alpha-(32)P]nucleoside triphosphates, cyclic [32P] AMP, and cyclic [32P] GMP. Biochim Biophys Acta 562:11-31
68. Xie CW (2004) Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction. Neuromolecular Med 6:53-64
69. Yang F, He XP, Russell J, Lu B (2003) Ca2+ influx-independent synaptic potentiation mediated by mitochondrial Na(+)-Ca2+ exchanger and protein kinase C. J Cell Biol 163:511-523
70. Zaidi A, Barron L, Sharov VS, Schoneich C, Michaelis EK, Michaelis ML (2003) Oxidative inactivation of purified plasma membrane Ca2+-ATPase by hydrogen peroxide and protection by calmodulin. Biochemistry 42:12001-12010
71. Zaidi A, Michaelis ML (1999) Effects of reactive oxygen species on brain synaptic plasma membrane Ca(2+)-ATPase. Free Radic Biol Med 27:810-821