-
1
-
-
0034911155
-
Genetic polymorphism of CYP2D6
-
Abraham, A. (2001). Genetic polymorphism of CYP2D6. Indian J. Pharmacol. 33:147-169.
-
(2001)
Indian J. Pharmacol
, vol.33
, pp. 147-169
-
-
Abraham, A.1
-
2
-
-
0036409283
-
The detection of large deletions or duplications in genomic DNA
-
Armour, J. A., Barton, D. E., Cockburn, D. J., Taylor, G. R. (2002). The detection of large deletions or duplications in genomic DNA. Hum. Mutat. 20:325-337.
-
(2002)
Hum. Mutat
, vol.20
, pp. 325-337
-
-
Armour, J.A.1
Barton, D.E.2
Cockburn, D.J.3
Taylor, G.R.4
-
3
-
-
0028211009
-
PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates
-
Barnes, W. M. (1994). PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. Proc. Natl. Acad. Sci. USA 91:2216-2220.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2216-2220
-
-
Barnes, W.M.1
-
4
-
-
0036204756
-
Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs
-
Bertilsson, L., Dahl, M. L., Dalen, P., Al-Shurbaji, A. (2002). Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs. Br. J. Clin. Pharmacol. 53:111-122.
-
(2002)
Br. J. Clin. Pharmacol
, vol.53
, pp. 111-122
-
-
Bertilsson, L.1
Dahl, M.L.2
Dalen, P.3
Al-Shurbaji, A.4
-
5
-
-
31044436017
-
Determination of cytochrome P450 2D6 (CYP2D6) gene copy number by real-time quantitative PCR
-
Bodin, L., Beaune, P. H., Loriot, M. A. (2005). Determination of cytochrome P450 2D6 (CYP2D6) gene copy number by real-time quantitative PCR. J. Biomed. Biotechnol. 2005:248-253.
-
(2005)
J. Biomed. Biotechnol
, vol.2005
, pp. 248-253
-
-
Bodin, L.1
Beaune, P.H.2
Loriot, M.A.3
-
6
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
Bradford, L. D. (2002). CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3:229-243.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 229-243
-
-
Bradford, L.D.1
-
7
-
-
0029622336
-
An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis
-
Broly, F., Marez, D., Sabbagh, N., Legrand, M., Millecamps, S., Lo Guidice, J. M., Boone, P., Meyer, U. A. (1995). An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis. Pharmacogenetics 5:373-384.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 373-384
-
-
Broly, F.1
Marez, D.2
Sabbagh, N.3
Legrand, M.4
Millecamps, S.5
Lo Guidice, J.M.6
Boone, P.7
Meyer, U.A.8
-
8
-
-
0028261194
-
Effective amplification of long targets from cloned inserts and human genomic DNA
-
Cheng, S., Fockler, C., Barnes, W. M., Higuchi, R. (1994). Effective amplification of long targets from cloned inserts and human genomic DNA. Proc. Natl. Acad. Sci. USA 91:5695-5699.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5695-5699
-
-
Cheng, S.1
Fockler, C.2
Barnes, W.M.3
Higuchi, R.4
-
9
-
-
0029758348
-
CYP2D6 multiallelism
-
Daly, A. K., Steen, V. M., Fairbrother, K. S., Idle, J. R. (1996). CYP2D6 multiallelism. Methods Enzymol. 272:199-210.
-
(1996)
Methods Enzymol
, vol.272
, pp. 199-210
-
-
Daly, A.K.1
Steen, V.M.2
Fairbrother, K.S.3
Idle, J.R.4
-
10
-
-
0037081031
-
Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction
-
Endrizzi, K., Fischer, J., Klein, K., Schwab, M., Nussler, A., Neuhaus, P., Eichelbaum, M., Zanger, U. M. (2002). Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction. Anal. Biochem. 300:121-131.
-
(2002)
Anal. Biochem
, vol.300
, pp. 121-131
-
-
Endrizzi, K.1
Fischer, J.2
Klein, K.3
Schwab, M.4
Nussler, A.5
Neuhaus, P.6
Eichelbaum, M.7
Zanger, U.M.8
-
11
-
-
0042843050
-
Cytochrome p450 genotyping by multiplexed real-time DNA sequencing with pyrosequencing technology
-
Eriksson, S., Berg, L. M., Wadelius, M., Alderborn, A. (2002). Cytochrome p450 genotyping by multiplexed real-time DNA sequencing with pyrosequencing technology. Assay Drug Dev. Technol. 1:49-59.
-
(2002)
Assay Drug Dev. Technol
, vol.1
, pp. 49-59
-
-
Eriksson, S.1
Berg, L.M.2
Wadelius, M.3
Alderborn, A.4
-
12
-
-
0025805934
-
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism
-
Gaedigk, A., Blum, M., Gaedigk, R., Eichelbaum, M., Meyer, U. A. (1991). Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism. Am. J. Hum. Genet. 48:943-950.
-
(1991)
Am. J. Hum. Genet
, vol.48
, pp. 943-950
-
-
Gaedigk, A.1
Blum, M.2
Gaedigk, R.3
Eichelbaum, M.4
Meyer, U.A.5
-
13
-
-
0036278859
-
Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream
-
Ginzinger, D. G. (2002). Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream. Exp. Hematol. 30:503-512.
-
(2002)
Exp. Hematol
, vol.30
, pp. 503-512
-
-
Ginzinger, D.G.1
-
14
-
-
14944377644
-
Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: Effects on cell survival, cell cycle and pharmacogenetic profile
-
Giovannetti, E., Mey, V., Danesi, R., Basolo, F., Barachini, S., Deri, M., Del Tacca, M. (2005). Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: Effects on cell survival, cell cycle and pharmacogenetic profile. Br. J. Cancer 92:681-689.
-
(2005)
Br. J. Cancer
, vol.92
, pp. 681-689
-
-
Giovannetti, E.1
Mey, V.2
Danesi, R.3
Basolo, F.4
Barachini, S.5
Deri, M.6
Del Tacca, M.7
-
15
-
-
0035710229
-
An overview of real-time quantitative PCR: Applications to quantify cytokine gene expression
-
Giulietti, A., Overbergh, L., Valckx, D., Decallonne, B., Bouillon, R., Mathieu, C. (2001). An overview of real-time quantitative PCR: Applications to quantify cytokine gene expression. Methods 25:386-401.
-
(2001)
Methods
, vol.25
, pp. 386-401
-
-
Giulietti, A.1
Overbergh, L.2
Valckx, D.3
Decallonne, B.4
Bouillon, R.5
Mathieu, C.6
-
16
-
-
0023854270
-
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
-
Gonzalez, F. J., Skoda, R. C., Kimura, S., Umeno, M., Zanger, U. M., Nebert, D. W., Gelboin, H. V., Hardwick, J. P., Meyer, U. A. (1988a). Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature 331:442-446.
-
(1988)
Nature
, vol.331
, pp. 442-446
-
-
Gonzalez, F.J.1
Skoda, R.C.2
Kimura, S.3
Umeno, M.4
Zanger, U.M.5
Nebert, D.W.6
Gelboin, H.V.7
Hardwick, J.P.8
Meyer, U.A.9
-
17
-
-
0023954396
-
Human debrisoquine 4-hydroxylase (P450IID1): CDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22
-
Gonzalez, F. J., Vilbois, F., Hardwick, J. P., McBride, O. W., Nebert, D. W., Gelboin, H. V., Meyer, U. A. (1988b). Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22. Genomics 2:174-179.
-
(1988)
Genomics
, vol.2
, pp. 174-179
-
-
Gonzalez, F.J.1
Vilbois, F.2
Hardwick, J.P.3
McBride, O.W.4
Nebert, D.W.5
Gelboin, H.V.6
Meyer, U.A.7
-
18
-
-
0027480849
-
Localization of the CYP2D gene locus to human chromosome 22q13.1 by polymerase chain reaction, in situ hybridization, and linkage analysis
-
Gough, A. C., Smith, C. A., Howell, S. M., Wolf, C. R., Bryant, S. P., Spurr, N. K. (1993). Localization of the CYP2D gene locus to human chromosome 22q13.1 by polymerase chain reaction, in situ hybridization, and linkage analysis. Genomics 15:430-432.
-
(1993)
Genomics
, vol.15
, pp. 430-432
-
-
Gough, A.C.1
Smith, C.A.2
Howell, S.M.3
Wolf, C.R.4
Bryant, S.P.5
Spurr, N.K.6
-
19
-
-
0034234293
-
Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: Association of polymorphisms with functional differences in estrogen hydroxylation activity
-
Hanna, I. H., Dawling, S., Roodi, N., Guengerich, F. P., Parl, F. F. (2000). Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity. Cancer Res. 60:3440-3444.
-
(2000)
Cancer Res
, vol.60
, pp. 3440-3444
-
-
Hanna, I.H.1
Dawling, S.2
Roodi, N.3
Guengerich, F.P.4
Parl, F.F.5
-
20
-
-
0025080352
-
Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
-
Heim, M., Meyer, U. A. (1990). Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 336:529-532.
-
(1990)
Lancet
, vol.336
, pp. 529-532
-
-
Heim, M.1
Meyer, U.A.2
-
21
-
-
0026629691
-
Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6
-
Heim, M. H., Meyer, U. A. (1992). Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6. Genomics 14:49-58.
-
(1992)
Genomics
, vol.14
, pp. 49-58
-
-
Heim, M.H.1
Meyer, U.A.2
-
22
-
-
0028488561
-
Methods and reagents. Long and accurate PCR
-
Hengen, P. N. (1994). Methods and reagents. Long and accurate PCR. TIBS 19:341-342.
-
(1994)
TIBS
, vol.19
, pp. 341-342
-
-
Hengen, P.N.1
-
23
-
-
0033871198
-
Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR
-
Hersberger, M., Marti-Jaun, J., Rentsch, K., Hanseler, E. (2000). Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR. Clin. Chem. 46:1072-1077.
-
(2000)
Clin. Chem
, vol.46
, pp. 1072-1077
-
-
Hersberger, M.1
Marti-Jaun, J.2
Rentsch, K.3
Hanseler, E.4
-
24
-
-
0033791142
-
High throughput detection of drug-metabolizing enzyme polymorphisms by allele-specific fluorogenic 5′ nuclease chain reaction assay
-
Hiratsuka, M., Agatsuma, Y., Omori, F., Narahara, K., Inoue, T., Kishikawa, Y., Mizugaki, M. (2000). High throughput detection of drug-metabolizing enzyme polymorphisms by allele-specific fluorogenic 5′ nuclease chain reaction assay. Biol. Pharm. Bull. 23:1131-1135.
-
(2000)
Biol. Pharm. Bull
, vol.23
, pp. 1131-1135
-
-
Hiratsuka, M.1
Agatsuma, Y.2
Omori, F.3
Narahara, K.4
Inoue, T.5
Kishikawa, Y.6
Mizugaki, M.7
-
25
-
-
0025861818
-
Detection of specific polymerase chain reaction product by utilizing the 5′ - 3′ exonuclease activity of Thermus aquaticus DNA polymerase
-
Holland, P. M., Abramson, R .D., Watson, R., Gelfand, D. H. (1991). Detection of specific polymerase chain reaction product by utilizing the 5′ - 3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. USA 88:7276-7280.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7276-7280
-
-
Holland, P.M.1
Abramson, R.D.2
Watson, R.3
Gelfand, D.H.4
-
26
-
-
1942421701
-
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: The past, present and future
-
Ingelman-Sundberg, M. (2004). Pharmacogenetics of cytochrome P450 and its applications in drug therapy: The past, present and future. Trends Pharmacol. Sci. 25:193-200.
-
(2004)
Trends Pharmacol. Sci
, vol.25
, pp. 193-200
-
-
Ingelman-Sundberg, M.1
-
27
-
-
13544249943
-
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
-
Ingelman-Sundberg, M. (2005). Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J. 5:6-13.
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 6-13
-
-
Ingelman-Sundberg, M.1
-
28
-
-
33644664657
-
Pharmacogenetics of drug-metabolizing enzymes: Implications for a safer and more effective drug therapy
-
Ingelman-Sundberg, M., Rodriguez-Antona, C. (2005). Pharmacogenetics of drug-metabolizing enzymes: Implications for a safer and more effective drug therapy. Philos. Trans. R. Soc. Lond. B Biol. Sci. 360:1563-1570.
-
(2005)
Philos. Trans. R. Soc. Lond. B Biol. Sci
, vol.360
, pp. 1563-1570
-
-
Ingelman-Sundberg, M.1
Rodriguez-Antona, C.2
-
29
-
-
0029756509
-
PCR-based genotyping for duplicated and deleted CYP2D6 genes
-
Johansson, I., Lundqvist, E., Dahl, M. L., Ingelman-Sundberg, M. (1996). PCR-based genotyping for duplicated and deleted CYP2D6 genes. Pharmacogenetics 6:351-355.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 351-355
-
-
Johansson, I.1
Lundqvist, E.2
Dahl, M.L.3
Ingelman-Sundberg, M.4
-
30
-
-
0024796958
-
The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
-
Kimura, S., Umeno, M., Skoda, R. C., Meyer, U. A., Gonzalez, F. J. (1989). The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am. J. Hum. Genet. 45:889-904.
-
(1989)
Am. J. Hum. Genet
, vol.45
, pp. 889-904
-
-
Kimura, S.1
Umeno, M.2
Skoda, R.C.3
Meyer, U.A.4
Gonzalez, F.J.5
-
31
-
-
23844516328
-
Pharmacogenetics-based therapeutic recommendations - ready for clinical practice?
-
Kirchheiner, J., Fuhr, U., Brockmoller, J. (2005). Pharmacogenetics-based therapeutic recommendations - ready for clinical practice? Nat. Rev. Drug Discov. 4:639-647.
-
(2005)
Nat. Rev. Drug Discov
, vol.4
, pp. 639-647
-
-
Kirchheiner, J.1
Fuhr, U.2
Brockmoller, J.3
-
32
-
-
3142519666
-
Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
-
Kirchheiner, J., Nickchen, K., Bauer, M., Wong, M. L., Licinio, J., Roots, I., Brockmoller, J. (2004). Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response. Mol. Psychiatry 9:442-473.
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 442-473
-
-
Kirchheiner, J.1
Nickchen, K.2
Bauer, M.3
Wong, M.L.4
Licinio, J.5
Roots, I.6
Brockmoller, J.7
-
33
-
-
19644377185
-
Identification of subtypes of CYP2D gene rearrangements among carriers of CYP2D6 gene deletion and duplication
-
Ledesma, M. C., Agundez, J. A. (2005). Identification of subtypes of CYP2D gene rearrangements among carriers of CYP2D6 gene deletion and duplication. Clin. Chem. 51:939-943.
-
(2005)
Clin. Chem
, vol.51
, pp. 939-943
-
-
Ledesma, M.C.1
Agundez, J.A.2
-
34
-
-
0007293059
-
Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene
-
Lovlie, R., Daly, A. K., Molven, A., Idle, J. R., Steen, V. M. (1996). Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene. FEBS Lett. 392:30-34.
-
(1996)
FEBS Lett
, vol.392
, pp. 30-34
-
-
Lovlie, R.1
Daly, A.K.2
Molven, A.3
Idle, J.R.4
Steen, V.M.5
-
35
-
-
0033590590
-
Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes
-
Lundqvist, E., Johansson, I., Ingelman-Sundberg, M. (1999). Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes. Gene 226:327-338.
-
(1999)
Gene
, vol.226
, pp. 327-338
-
-
Lundqvist, E.1
Johansson, I.2
Ingelman-Sundberg, M.3
-
36
-
-
0036020649
-
Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics
-
Mattison, L. K., Soong, R., Diasio, R. B. (2002). Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics. Pharmacogenomics 3:485-492.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 485-492
-
-
Mattison, L.K.1
Soong, R.2
Diasio, R.B.3
-
37
-
-
0036009619
-
The thiopurine S-methyltransferase gene locus - implications for clinical pharmacogenomics
-
McLeod, H. L., Siva, C. (2002). The thiopurine S-methyltransferase gene locus - implications for clinical pharmacogenomics. Pharmacogenomics 3:89-98.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 89-98
-
-
McLeod, H.L.1
Siva, C.2
-
38
-
-
0025259226
-
The genetic polymorphism of debrisoquine/ sparteine metabolism-molecular mechanisms
-
Meyer, U. A., Skoda, R. C., Zanger, U. M. (1990). The genetic polymorphism of debrisoquine/ sparteine metabolism-molecular mechanisms. Pharmacol. Ther. 46:297-308.
-
(1990)
Pharmacol. Ther
, vol.46
, pp. 297-308
-
-
Meyer, U.A.1
Skoda, R.C.2
Zanger, U.M.3
-
39
-
-
0037495962
-
Quantitative real-time PCR: A powerful ally in cancer research
-
Mocellin, S., Rossi, C. R., Pilati, P., Nitti, D., Marincola, F. M. (2003). Quantitative real-time PCR: A powerful ally in cancer research. Trends Mol. Med. 9:189-195.
-
(2003)
Trends Mol. Med
, vol.9
, pp. 189-195
-
-
Mocellin, S.1
Rossi, C.R.2
Pilati, P.3
Nitti, D.4
Marincola, F.M.5
-
40
-
-
17444453992
-
Optimized strategy for rapid cytochrome P450 2D6 genotyping by real-time long PCR
-
Muller, B., Zopf, K., Bachofer, J., Steimer, W. (2003). Optimized strategy for rapid cytochrome P450 2D6 genotyping by real-time long PCR. Clin. Chem. 49:1624-1631.
-
(2003)
Clin. Chem
, vol.49
, pp. 1624-1631
-
-
Muller, B.1
Zopf, K.2
Bachofer, J.3
Steimer, W.4
-
41
-
-
0034783988
-
CYP2D6 genotyping with oligonucleotide microarrays and nortriptyline concentrations in geriatric depression
-
Murphy, G. M., Pollock, B. G., Kirshner, M. A., Pascoe, N., Cheuk, W., Mulsant, B. H., Reynolds, C. F. (2001). CYP2D6 genotyping with oligonucleotide microarrays and nortriptyline concentrations in geriatric depression. Neuropsychopharmacology 25:737-743.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 737-743
-
-
Murphy, G.M.1
Pollock, B.G.2
Kirshner, M.A.3
Pascoe, N.4
Cheuk, W.5
Mulsant, B.H.6
Reynolds, C.F.7
-
42
-
-
0035861049
-
Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
-
Phillips, K. A., Veenstra, D. L., Oren, E., Lee, J. K., Sadee, W. (2001). Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review. JAMA 286:2270-2279.
-
(2001)
JAMA
, vol.286
, pp. 2270-2279
-
-
Phillips, K.A.1
Veenstra, D.L.2
Oren, E.3
Lee, J.K.4
Sadee, W.5
-
43
-
-
3042723720
-
Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18 820 patients
-
Pirmohamed, M., James, S., Meakin, S., Green, C., Scott, A. K., Walley, T. J., Farrar, K., Park, B. K., Breckenridge, A. M. (2004). Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ 329:15-19.
-
(2004)
BMJ
, vol.329
, pp. 15-19
-
-
Pirmohamed, M.1
James, S.2
Meakin, S.3
Green, C.4
Scott, A.K.5
Walley, T.J.6
Farrar, K.7
Park, B.K.8
Breckenridge, A.M.9
-
44
-
-
0033921510
-
Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction
-
Roberts, R., Joyce, P., Kennedy, M. A. (2000). Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction. Hum. Mutat. 16:77-85.
-
(2000)
Hum. Mutat
, vol.16
, pp. 77-85
-
-
Roberts, R.1
Joyce, P.2
Kennedy, M.A.3
-
45
-
-
33644683245
-
Rapid detection of common cytochrome P450 2D6 alleles in Caucasians
-
Roberts, R. L., Kennedy, M. A. (2006). Rapid detection of common cytochrome P450 2D6 alleles in Caucasians. Clin. Chim. Acta 366:348-351.
-
(2006)
Clin. Chim. Acta
, vol.366
, pp. 348-351
-
-
Roberts, R.L.1
Kennedy, M.A.2
-
46
-
-
0346363770
-
CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR
-
Schaeffeler, E., Schwab, M., Eichelbaum, M., Zanger, U. M. (2003). CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR. Hum. Mutat. 22:476-485.
-
(2003)
Hum. Mutat
, vol.22
, pp. 476-485
-
-
Schaeffeler, E.1
Schwab, M.2
Eichelbaum, M.3
Zanger, U.M.4
-
47
-
-
0034974138
-
Genotyping of cytochrome P450 2D6*3 and *4 mutations using conventional PCR
-
Schur, B. C., Bjerke, J., Nuwayhid, N., Wong, S. H. (2001). Genotyping of cytochrome P450 2D6*3 and *4 mutations using conventional PCR. Clin. Chim. Acta 308:25-31.
-
(2001)
Clin. Chim. Acta
, vol.308
, pp. 25-31
-
-
Schur, B.C.1
Bjerke, J.2
Nuwayhid, N.3
Wong, S.H.4
-
48
-
-
2342578875
-
MLPA and MAPH: New techniques for detection of gene deletions
-
Sellner, L. N., Taylor, G. R. (2004). MLPA and MAPH: New techniques for detection of gene deletions. Hum. Mutat. 23:413-419.
-
(2004)
Hum. Mutat
, vol.23
, pp. 413-419
-
-
Sellner, L.N.1
Taylor, G.R.2
-
49
-
-
1642483471
-
Feed-forward regulation of bile acid detoxification by CYP3A4 - Studies in humanized transgenic mice
-
Stedman, C., Robertson, G., Coulter, S., Liddle, C. (2004). Feed-forward regulation of bile acid detoxification by CYP3A4 - Studies in humanized transgenic mice. J. Biol. Chem. 279:11336-11343.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 11336-11343
-
-
Stedman, C.1
Robertson, G.2
Coulter, S.3
Liddle, C.4
-
50
-
-
0029102348
-
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
-
Steen, V. M., Andreassen, O. A., Daly, A. K., Tefre, T., Borresen, A. L., Idle, J. R., Gulbrandsen, A. K. (1995). Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology. Pharmacogenetics 5:215-223.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 215-223
-
-
Steen, V.M.1
Andreassen, O.A.2
Daly, A.K.3
Tefre, T.4
Borresen, A.L.5
Idle, J.R.6
Gulbrandsen, A.K.7
-
51
-
-
0031923119
-
Ultrarapid drug metabolism: PCR-based detection of CYP2D6 gene duplication
-
Steijns, L. S., Van Der Weide, J. (1998). Ultrarapid drug metabolism: PCR-based detection of CYP2D6 gene duplication. Clin. Chem. 44:914-917.
-
(1998)
Clin. Chem
, vol.44
, pp. 914-917
-
-
Steijns, L.S.1
Van Der Weide, J.2
-
52
-
-
0029846193
-
Rapid detection of CYP2D6 null alleles by long distance- and multiplex-polymerase chain reaction
-
Stuven, T., Griese, E. U., Kroemer, H. K., Eichelbaum, M., Zanger, U. M. (1996). Rapid detection of CYP2D6 null alleles by long distance- and multiplex-polymerase chain reaction. Pharmacogenetics 6:417-421.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 417-421
-
-
Stuven, T.1
Griese, E.U.2
Kroemer, H.K.3
Eichelbaum, M.4
Zanger, U.M.5
-
53
-
-
0033759596
-
CYP2D6 genotyping in patients on psychoactive drug therapy
-
Topic, E., Stefanovic, M., Ivanisevic, A. M., Blazinic, F., Culav, J., Skocilic, Z. (2000). CYP2D6 genotyping in patients on psychoactive drug therapy. Clin. Chem. Lab. Med. 38:921-927.
-
(2000)
Clin. Chem. Lab. Med
, vol.38
, pp. 921-927
-
-
Topic, E.1
Stefanovic, M.2
Ivanisevic, A.M.3
Blazinic, F.4
Culav, J.5
Skocilic, Z.6
-
54
-
-
0344012538
-
Real-time polymerase chain reaction
-
Wilhelm, J., Pingoud, A. (2003). Real-time polymerase chain reaction. ChemBioChem. 4:1120-1128.
-
(2003)
ChemBioChem
, vol.4
, pp. 1120-1128
-
-
Wilhelm, J.1
Pingoud, A.2
-
55
-
-
0742286803
-
Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
Zanger, U. M., Raimundo, S., Eichelbaum, M. (2004). Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch. Pharmacol. 369:23-37.
-
(2004)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.369
, pp. 23-37
-
-
Zanger, U.M.1
Raimundo, S.2
Eichelbaum, M.3
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