메뉴 건너뛰기




Volumn 6, Issue 4, 1996, Pages 351-355

PCR-based genotyping for duplicated and deleted CYP2D6 genes

Author keywords

Cytochrome P450; Debrisoquine; Gene amplification; Gene duplication; Long PCR; Neuroleptics; Sparteine; Tricyclic antidepressants

Indexed keywords

CYTOCHROME P450 ISOENZYME; DEBRISOQUINE; DNA; NEUROLEPTIC AGENT; OXYGENASE; SPARTEINE; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 0029756509     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199608000-00008     Document Type: Article
Times cited : (105)

References (12)
  • 1
    • 0028942981 scopus 로고
    • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
    • Agúndez JAG, Ledesma MC, Ladero JM, Benitez J. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995: 57, 265-269.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 265-269
    • Agúndez, J.A.G.1    Ledesma, M.C.2    Ladero, J.M.3    Benitez, J.4
  • 3
    • 0001935587 scopus 로고
    • Interindividual and interethnic differences in polymorphic drug oxidation - Implications for drug therapy with focus on psychoactive drugs
    • Pacifici G, Fracchia GN, eds EUR 15439 EN, EC, DGXII-E-4
    • Bertilsson L, Dahl M-L, Ingelman-Sundberg M, Johansson I, Sjöqvist F. Interindividual and interethnic differences in polymorphic drug oxidation - implications for drug therapy with focus on psychoactive drugs. In: Pacifici G, Fracchia GN, eds Advances in drug metabolism in man, EUR 15439 EN, EC, DGXII-E-4, 1995: 85-136.
    • (1995) Advances in Drug Metabolism in Man , pp. 85-136
    • Bertilsson, L.1    Dahl, M.-L.2    Ingelman-Sundberg, M.3    Johansson, I.4    Sjöqvist, F.5
  • 4
    • 0028261194 scopus 로고
    • Effective amplification of long targets from cloned inserts and human genomic DNA
    • Cheng S, Fockler C, Barnes WM, Higuchi R. Effective amplification of long targets from cloned inserts and human genomic DNA. Proc Natl Acad Sci (USA) 1994: 91, 5695-5699.
    • (1994) Proc Natl Acad Sci (USA) , vol.91 , pp. 5695-5699
    • Cheng, S.1    Fockler, C.2    Barnes, W.M.3    Higuchi, R.4
  • 5
    • 0029064096 scopus 로고
    • Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis
    • Dahl ML, Johansson I, Bertilsson L, Ingelman-Sundberg M, Sjöqvist F. Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis. J Pharmacol Exp Ther 1995: 274, 516-520.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 516-520
    • Dahl, M.L.1    Johansson, I.2    Bertilsson, L.3    Ingelman-Sundberg, M.4    Sjöqvist, F.5
  • 6
    • 0025805934 scopus 로고
    • Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism
    • Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism. Am J Hum Genet 1991: 48, 943-950.
    • (1991) Am J Hum Genet , vol.48 , pp. 943-950
    • Gaedigk, A.1    Blum, M.2    Gaedigk, R.3    Eichelbaum, M.4    Meyer, U.A.5
  • 7
    • 0025080352 scopus 로고
    • Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
    • Heim M, Meyer UA. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 1990: 336, 529-532.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 8
    • 0028488561 scopus 로고
    • Methods and reagents - Long and accurate PCR
    • Hengen PN. Methods and reagents - long and accurate PCR. Trends Biochem Sci 1994: 19, 341-342
    • (1994) Trends Biochem Sci , vol.19 , pp. 341-342
    • Hengen, P.N.1
  • 9
    • 0003330406 scopus 로고
    • The molecular genetics of the human drug metabolizing cytochrome P450s
    • Pacific G. Fracchia eds, EUR 15439 EN, EC, DGXII-E-4, Luxembourg: Office for official publications of the European Communities
    • Ingelman-Sundberg M, Johansson I. The molecular genetics of the human drug metabolizing cytochrome P450s. In: Pacific G. Fracchia eds, Advances in drug metabolism in man, EUR 15439 EN, EC, DGXII-E-4, Luxembourg: Office for official publications of the European Communities 1995: 543-586.
    • (1995) Advances in Drug Metabolism in Man , pp. 543-586
    • Ingelman-Sundberg, M.1    Johansson, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.