-
1
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal A et al. (2006) Cancer statistics, 2006. CA Cancer J Clin 56: 106-130
-
(2006)
CA Cancer J Clin
, vol.56
, pp. 106-130
-
-
Jemal, A.1
-
2
-
-
0036789479
-
Nomogram for overall survival of patients with progressive metastatic prostate cancer after castration
-
Smaletz O et al. (2002) Nomogram for overall survival of patients with progressive metastatic prostate cancer after castration. J Clin Oncol 20: 3972-3982
-
(2002)
J Clin Oncol
, vol.20
, pp. 3972-3982
-
-
Smaletz, O.1
-
3
-
-
33646576828
-
Androgen receptor as a therapeutic target for androgen independent prostate cancer
-
Sharifi N and Farrar WL (2006) Androgen receptor as a therapeutic target for androgen independent prostate cancer. Am J Ther 13:166-170
-
(2006)
Am J Ther
, vol.13
, pp. 166-170
-
-
Sharifi, N.1
Farrar, W.L.2
-
4
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman BJ and Feldman D (2001) The development of androgen-independent prostate cancer. Nat Rev Cancer 1:34-45
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
5
-
-
15844429706
-
Mechanisms of the development of androgen independence in prostate cancer
-
So A et al. (2005) Mechanisms of the development of androgen independence in prostate cancer. World J Urol 23: 1-9
-
(2005)
World J Urol
, vol.23
, pp. 1-9
-
-
So, A.1
-
6
-
-
18844373937
-
Transcriptional regulation by steroid receptor coactivator phosphorylation
-
Wu RC et al. (2005) Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr Rev 26: 393-399
-
(2005)
Endocr Rev
, vol.26
, pp. 393-399
-
-
Wu, R.C.1
-
7
-
-
12344338583
-
Expression and function of androgen receptor coactivators in prostate cancer
-
Culig Z et al. (2004) Expression and function of androgen receptor coactivators in prostate cancer. J Steroid Biochem Mol Biol 92: 265-271
-
(2004)
J Steroid Biochem Mol Biol
, vol.92
, pp. 265-271
-
-
Culig, Z.1
-
8
-
-
0033555967
-
Activation of mitogen-activated protein kinase associated with prostate cancer progression
-
Gioeli D et al. (1999) Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 59: 279-284
-
(1999)
Cancer Res
, vol.59
, pp. 279-284
-
-
Gioeli, D.1
-
9
-
-
0042477896
-
Involvement of growth factor receptors of the epidermal growth factor receptor family in prostate cancer development and progression to androgen independence
-
Lorenzo GD et al. (2003) Involvement of growth factor receptors of the epidermal growth factor receptor family in prostate cancer development and progression to androgen independence. Clin Prostate Cancer 2: 50-57
-
(2003)
Clin Prostate Cancer
, vol.2
, pp. 50-57
-
-
Lorenzo, G.D.1
-
10
-
-
2342456382
-
Trastuzumab plus docetaxel in HER-2/neu-positive prostate carcinoma: Final results from the California Cancer Consortium Screening and Phase II Trial
-
Lara PN Jr et al. (2004) Trastuzumab plus docetaxel in HER-2/ neu-positive prostate carcinoma: Final results from the California Cancer Consortium Screening and Phase II Trial. Cancer 100: 2125-2131
-
(2004)
Cancer
, vol.100
, pp. 2125-2131
-
-
Lara Jr., P.N.1
-
11
-
-
3943104783
-
The use of trastuzumab in the treatment of hormone refractory prostate cancer; phase II trial
-
Ziada A et al. (2004) The use of trastuzumab in the treatment of hormone refractory prostate cancer; phase II trial. Prostate 80: 332-337
-
(2004)
Prostate
, vol.80
, pp. 332-337
-
-
Ziada, A.1
-
12
-
-
0346365445
-
Smart drugs in prostate cancer
-
van der Poel HG (2004) Smart drugs in prostate cancer. Eur Urol. 45: 1-17
-
(2004)
Eur Urol
, vol.45
, pp. 1-17
-
-
van der Poel, H.G.1
-
13
-
-
18244404560
-
Future therapies in hormone-refractory prostate cancer
-
discussion 17
-
Smith MR and Nelson JB (2005) Future therapies in hormone-refractory prostate cancer. Urology 65: 9-16; discussion 17
-
(2005)
Urology
, vol.65
, pp. 9-16
-
-
Smith, M.R.1
Nelson, J.B.2
-
14
-
-
20044372705
-
Randomized phase II study of two doses of gefitinib in hormone-refractory prostate cancer: A trial of the National Cancer Institute of Canada-Clinical Trials Group
-
Canil CM et al. (2005) Randomized phase II study of two doses of gefitinib in hormone-refractory prostate cancer: A trial of the National Cancer Institute of Canada-Clinical Trials Group. J Clin Oncol 23: 455-460
-
(2005)
J Clin Oncol
, vol.23
, pp. 455-460
-
-
Canil, C.M.1
-
15
-
-
9244242088
-
Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model
-
Krueckl SL et al. (2004) Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model. Cancer Res 64: 8620-8629
-
(2004)
Cancer Res
, vol.64
, pp. 8620-8629
-
-
Krueckl, S.L.1
-
16
-
-
0034213320
-
Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models
-
Miyake H et al. (2000) Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models. Cancer Res 60: 3058-3064
-
(2000)
Cancer Res
, vol.60
, pp. 3058-3064
-
-
Miyake, H.1
-
17
-
-
0038756444
-
Castration-induced increases in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors
-
Kiyama S et al. (2003) Castration-induced increases in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors. Cancer Res 63: 3575-3584
-
(2003)
Cancer Res
, vol.63
, pp. 3575-3584
-
-
Kiyama, S.1
-
18
-
-
2942583126
-
Expression of insulin-like growth factor binding protein-3 before and after neoadjuvant hormonal therapy in human prostate cancer tissues: Correlation with histopathologic effects and biochemical recurrence
-
Miyata Y et al. (2004) Expression of insulin-like growth factor binding protein-3 before and after neoadjuvant hormonal therapy in human prostate cancer tissues: Correlation with histopathologic effects and biochemical recurrence. Urology 63:1184-1190
-
(2004)
Urology
, vol.63
, pp. 1184-1190
-
-
Miyata, Y.1
-
19
-
-
0031889217
-
Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression
-
Papandreou CN et al. (1998) Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression. Nat Med 4: 50-57
-
(1998)
Nat Med
, vol.4
, pp. 50-57
-
-
Papandreou, C.N.1
-
20
-
-
0035204477
-
Neuropeptide-induced androgen independence in prostate cancer cells: Roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase
-
Lee LF et al. (2001) Neuropeptide-induced androgen independence in prostate cancer cells: Roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol 21: 8385-8397
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8385-8397
-
-
Lee, L.F.1
-
22
-
-
33745243692
-
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
-
Song L et al. (2006) Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res 66: 5542-5548
-
(2006)
Cancer Res
, vol.66
, pp. 5542-5548
-
-
Song, L.1
-
23
-
-
33846965767
-
Src kinase inhibition of neuropeptide-induced androgen-independent prostate cancer
-
Yang JC et al. (2005) Src kinase inhibition of neuropeptide-induced androgen-independent prostate cancer. Proc Amer Assoc Cancer Res 46: 3180
-
(2005)
Proc Amer Assoc Cancer Res
, vol.46
, pp. 3180
-
-
Yang, J.C.1
-
24
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
Nam S et al. (2005) Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res 65: 9185-9189
-
(2005)
Cancer Res
, vol.65
, pp. 9185-9189
-
-
Nam, S.1
-
25
-
-
0027093255
-
Expression of the protooncogene bc1-2 in the prostate and its association with emergence of androgen-independent prostate cancer
-
McDonnell TJ et al. (1992) Expression of the protooncogene bc1-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res 52: 6940-6944
-
(1992)
Cancer Res
, vol.52
, pp. 6940-6944
-
-
McDonnell, T.J.1
-
26
-
-
0027773015
-
Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers
-
Colombel M et al. (1993) Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers. Am J Pathol 143: 390-400
-
(1993)
Am J Pathol
, vol.143
, pp. 390-400
-
-
Colombel, M.1
-
27
-
-
33644788932
-
Role of coordinated molecular alterations in the development of androgen-independent prostate cancer: An in vitro model that corroborates clinical observations
-
Shi Y et al. (2006) Role of coordinated molecular alterations in the development of androgen-independent prostate cancer: An in vitro model that corroborates clinical observations. BJU Int 97: 170-178
-
(2006)
BJU Int
, vol.97
, pp. 170-178
-
-
Shi, Y.1
-
28
-
-
0035570021
-
Novel therapeutic strategy for advanced prostate cancer using antisense oligodeoxynucleotides targeting anti-apoptotic genes upregulated after androgen withdrawal to delay androgen-independent progression and enhance chemosensitivity
-
Miyake H et al. (2001) Novel therapeutic strategy for advanced prostate cancer using antisense oligodeoxynucleotides targeting anti-apoptotic genes upregulated after androgen withdrawal to delay androgen-independent progression and enhance chemosensitivity. Int J Urol 8: 337-349
-
(2001)
Int J Urol
, vol.8
, pp. 337-349
-
-
Miyake, H.1
-
29
-
-
21044431880
-
A phase II, pharmacokinetic, and biological correlative study of oblimersen sodium and docetaxel in patients with hormone-refractory prostate cancer
-
Tolcher AW et al. (2005) A phase II, pharmacokinetic, and biological correlative study of oblimersen sodium and docetaxel in patients with hormone-refractory prostate cancer. Clin Cancer Res 11: 3854-3861
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3854-3861
-
-
Tolcher, A.W.1
-
30
-
-
28744441818
-
Beyond simple castration: Targeting the molecular basis of treatment resistance in advanced prostate cancer
-
Gleave M et al. (2005) Beyond simple castration: Targeting the molecular basis of treatment resistance in advanced prostate cancer. Cancer Chemother Pharmacol 56 (Suppl 1): 47-57
-
(2005)
Cancer Chemother Pharmacol
, vol.56
, Issue.SUPPL. 1
, pp. 47-57
-
-
Gleave, M.1
-
31
-
-
0037083472
-
Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
-
July LV et al. (2002) Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate 50: 179-188
-
(2002)
Prostate
, vol.50
, pp. 179-188
-
-
July, L.V.1
-
32
-
-
28444443360
-
Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinic
-
Miyake H et al. (2005) Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinic. Int J Urol 12: 785-794
-
(2005)
Int J Urol
, vol.12
, pp. 785-794
-
-
Miyake, H.1
-
33
-
-
24744470522
-
A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleoticle to clusterin, in patients with localized prostate cancer
-
Chi KN et al. (2005) A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleoticle to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst 97: 1287-1296
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1287-1296
-
-
Chi, K.N.1
-
34
-
-
0032927729
-
Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: Prognostic significance of p21/WAF1/CIP1 expression
-
Baretton GB et al. (1999) Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: Prognostic significance of p21/WAF1/CIP1 expression. Br J Cancer 80: 546-555
-
(1999)
Br J Cancer
, vol.80
, pp. 546-555
-
-
Baretton, G.B.1
-
35
-
-
0033104627
-
Early castration-induced upregulation of transforming growth factor beta1 and its receptors is associated with tumor cell apoptosis and a major decline in serum prostate-specific antigen in prostate cancer patients
-
Wikstrom P et al. (1999) Early castration-induced upregulation of transforming growth factor beta1 and its receptors is associated with tumor cell apoptosis and a major decline in serum prostate-specific antigen in prostate cancer patients. Prostate 38: 268-277
-
(1999)
Prostate
, vol.38
, pp. 268-277
-
-
Wikstrom, P.1
-
36
-
-
0037187334
-
Vascular endothelial growth factor and signaling in the prostate: More than angiogenesis
-
Chevalier S et al. (2002) Vascular endothelial growth factor and signaling in the prostate: More than angiogenesis. Mol Cell Endocrinol 189: 169-179
-
(2002)
Mol Cell Endocrinol
, vol.189
, pp. 169-179
-
-
Chevalier, S.1
-
37
-
-
0034772250
-
Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
-
George DJ et al. (2001) Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 7: 1932-1936
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1932-1936
-
-
George, D.J.1
-
38
-
-
11144232324
-
Angiogenesis-targeted therapies in prostate cancer
-
Lara PN Jr et al. (2004) Angiogenesis-targeted therapies in prostate cancer. Clin Prostate Cancer 3: 165-173
-
(2004)
Clin Prostate Cancer
, vol.3
, pp. 165-173
-
-
Lara Jr., P.N.1
-
39
-
-
0346880557
-
The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006
-
Picus J et al. (2003) The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006. Proc Am Soc Clin Oncol 22: 393
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 393
-
-
Picus, J.1
-
40
-
-
0031915021
-
Integrin signalling and tyrosine phosphorylation: Just the FAKs?
-
Schlaepfer DD and Hunter T (1998) Integrin signalling and tyrosine phosphorylation: Just the FAKs? Trends Cell Biol 8: 151-157
-
(1998)
Trends Cell Biol
, vol.8
, pp. 151-157
-
-
Schlaepfer, D.D.1
Hunter, T.2
-
41
-
-
0034834329
-
Fibronectin, integrins, and growth control
-
Danen EH and Yamada KM (2001) Fibronectin, integrins, and growth control. J Cell Physiol 189: 1-13
-
(2001)
J Cell Physiol
, vol.189
, pp. 1-13
-
-
Danen, E.H.1
Yamada, K.M.2
-
42
-
-
4344713411
-
Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer
-
Stewart DA et al. (2004) Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer. Reprod Biol Endocrinol 2: 2
-
(2004)
Reprod Biol Endocrinol
, vol.2
, pp. 2
-
-
Stewart, D.A.1
-
43
-
-
0032912305
-
Differentially expressed genes in hormone refractory prostate cancer: Association with chromosomal regions involved with genetic aberrations
-
Stubbs AP et al. (1999) Differentially expressed genes in hormone refractory prostate cancer: Association with chromosomal regions involved with genetic aberrations. Am J Pathol 154: 1335-1343
-
(1999)
Am J Pathol
, vol.154
, pp. 1335-1343
-
-
Stubbs, A.P.1
-
44
-
-
1542269244
-
Mucinous differentiation features associated with hormonal escape in a human prostate cancer xenograft
-
Legrier ME et al. (2004) Mucinous differentiation features associated with hormonal escape in a human prostate cancer xenograft. Br J Cancer 90: 720-727
-
(2004)
Br J Cancer
, vol.90
, pp. 720-727
-
-
Legrier, M.E.1
-
45
-
-
33744546327
-
A pilot study of the liposomal MUC1 vaccine BLP25 in prostate specific antigen failures after radical prostatectomy
-
North SA et al. (2006) A pilot study of the liposomal MUC1 vaccine BLP25 in prostate specific antigen failures after radical prostatectomy. J Urol 176: 91-95
-
(2006)
J Urol
, vol.176
, pp. 91-95
-
-
North, S.A.1
-
46
-
-
33646047101
-
Effects of the natural isoflavonoid genistein on growth, signaling pathways and gene expression of matrix macromolecules by breast cancer cells
-
Kousidou O et al. (2006) Effects of the natural isoflavonoid genistein on growth, signaling pathways and gene expression of matrix macromolecules by breast cancer cells. Mini Rev Med Chem 6: 331-337
-
(2006)
Mini Rev Med Chem
, vol.6
, pp. 331-337
-
-
Kousidou, O.1
-
47
-
-
3442882798
-
Bortezomib as a potential treatment for prostate cancer
-
Papandreou CN and Logothetis CJ (2004) Bortezomib as a potential treatment for prostate cancer. Cancer Res 64: 5036-5043
-
(2004)
Cancer Res
, vol.64
, pp. 5036-5043
-
-
Papandreou, C.N.1
Logothetis, C.J.2
-
48
-
-
0036020941
-
NF-kappaB as a therapeutic target in cancer
-
Orlowski RZ and Baldwin AS Jr (2002) NF-kappaB as a therapeutic target in cancer. Trends Mol Med 8: 385-389
-
(2002)
Trends Mol Med
, vol.8
, pp. 385-389
-
-
Orlowski, R.Z.1
Baldwin Jr., A.S.2
-
49
-
-
11144226386
-
Phase I/II trial of bortezomib plus docetaxell in patients with advanced androgen-independent prostate cancer
-
Price N and Dreicer R (2004) Phase I/II trial of bortezomib plus docetaxell in patients with advanced androgen-independent prostate cancer. Clin Prostate Cancer 3: 141-143
-
(2004)
Clin Prostate Cancer
, vol.3
, pp. 141-143
-
-
Price, N.1
Dreicer, R.2
-
50
-
-
2942692143
-
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
-
Papandreou CN et al. (2004) Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol 22: 2108-2121
-
(2004)
J Clin Oncol
, vol.22
, pp. 2108-2121
-
-
Papandreou, C.N.1
-
51
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP et al. (2004) Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 351: 1513-1520
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
-
52
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF et al. (2004) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 351: 1502-1512
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
-
53
-
-
10344234761
-
Molecular insights into prostate cancer progression: The missing link of tumor microenvironment
-
Chung LW et al. (2005) Molecular insights into prostate cancer progression: The missing link of tumor microenvironment. J Urol 173: 10-20
-
(2005)
J Urol
, vol.173
, pp. 10-20
-
-
Chung, L.W.1
-
54
-
-
0032535307
-
Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
-
Gregory CW et al. (1998) Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Res 58: 5718-5724
-
(1998)
Cancer Res
, vol.58
, pp. 5718-5724
-
-
Gregory, C.W.1
-
55
-
-
3042536209
-
Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status
-
Hong H et al. (2004) Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status. Cancer 101: 83-89
-
(2004)
Cancer
, vol.101
, pp. 83-89
-
-
Hong, H.1
-
56
-
-
0037108955
-
p300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6
-
Debes JD et al. (2002) p300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6. Cancer Res 62: 5632-5636
-
(2002)
Cancer Res
, vol.62
, pp. 5632-5636
-
-
Debes, J.D.1
-
57
-
-
0037693192
-
Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development
-
Halkidou K et al. (2003) Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development. Oncogene 22: 2466-2477
-
(2003)
Oncogene
, vol.22
, pp. 2466-2477
-
-
Halkidou, K.1
-
58
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
Culig Z et al. (1994) Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 54: 5474-5478
-
(1994)
Cancer Res
, vol.54
, pp. 5474-5478
-
-
Culig, Z.1
-
59
-
-
0032718180
-
aFGF immunoreactivity in prostate cancer and its co-localization with bFGF and FGF8
-
Dorkin TJ et al. (1999) aFGF immunoreactivity in prostate cancer and its co-localization with bFGF and FGF8. J Pathol 189: 564-569
-
(1999)
J Pathol
, vol.189
, pp. 564-569
-
-
Dorkin, T.J.1
-
60
-
-
7244229599
-
Microarray analysis of prostate cancer progression to reduced androgen dependence: Studies in unique models contrasts early and late molecular events
-
Sirotnak FM et al. (2004) Microarray analysis of prostate cancer progression to reduced androgen dependence: Studies in unique models contrasts early and late molecular events. Mol Carcinog 41: 150-163
-
(2004)
Mol Carcinog
, vol.41
, pp. 150-163
-
-
Sirotnak, F.M.1
-
61
-
-
0033589283
-
Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays
-
Bubendorf L et al. (1999) Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays. J Natl Cancer Inst 91: 1758-1764
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1758-1764
-
-
Bubendorf, L.1
-
62
-
-
0035176826
-
Vascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: Evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts
-
Stewart RJ et al. (2001) Vascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: Evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts. J Urol 165: 688-693
-
(2001)
J Urol
, vol.165
, pp. 688-693
-
-
Stewart, R.J.1
-
63
-
-
25444527204
-
Vascular endothelial growth factor expression in untreated and androgen-deprived patients with prostate cancer
-
Aslan G et al. (2005) Vascular endothelial growth factor expression in untreated and androgen-deprived patients with prostate cancer. Pathol Res Pract 201: 593-598
-
(2005)
Pathol Res Pract
, vol.201
, pp. 593-598
-
-
Aslan, G.1
-
64
-
-
11144322016
-
Expression patterns of potential therapeutic targets in prostate cancer
-
Zellweger T et al. (2005) Expression patterns of potential therapeutic targets in prostate cancer. Int J Cancer 113: 619-628
-
(2005)
Int J Cancer
, vol.113
, pp. 619-628
-
-
Zellweger, T.1
-
65
-
-
0036680093
-
Down-regulation of (IIIb) and (IIIc) isoforms of fibroblast growth factor receptor 2 (FGFR2) is associated with malignant progression in human prostate
-
Naimi B et al. (2002) Down-regulation of (IIIb) and (IIIc) isoforms of fibroblast growth factor receptor 2 (FGFR2) is associated with malignant progression in human prostate. Prostate 52: 245-252
-
(2002)
Prostate
, vol.52
, pp. 245-252
-
-
Naimi, B.1
-
66
-
-
19744374755
-
Expression of serotonin receptors 2B and 4 in human prostate cancer tissue and effects of their antagonists on prostate cancer cell lines
-
Dizeyi N et al. (2005) Expression of serotonin receptors 2B and 4 in human prostate cancer tissue and effects of their antagonists on prostate cancer cell lines. Eur Urol 47: 895-900
-
(2005)
Eur Urol
, vol.47
, pp. 895-900
-
-
Dizeyi, N.1
-
67
-
-
0034131990
-
Androgen deprivation of the PC-310 [correction of prohormone convertase-310] human prostate cancer model system induces neuroendocrine differentiation
-
Jongsma J et al. (2000) Androgen deprivation of the PC-310 [correction of prohormone convertase-310] human prostate cancer model system induces neuroendocrine differentiation. Cancer Res 60: 741-748
-
(2000)
Cancer Res
, vol.60
, pp. 741-748
-
-
Jongsma, J.1
-
68
-
-
0037080268
-
Neuropeptides bombesin and calcitonin inhibit apoptosis-related elemental changes in prostate carcinoma cell lines
-
Salido M et al. (2002) Neuropeptides bombesin and calcitonin inhibit apoptosis-related elemental changes in prostate carcinoma cell lines. Cancer 94: 368-377
-
(2002)
Cancer
, vol.94
, pp. 368-377
-
-
Salido, M.1
-
69
-
-
0344826674
-
Regulatory effect of castration on endothelins, their receptors and endothelin-converting enzyme in rat seminal vesicle
-
Takahashi W et al. (2003) Regulatory effect of castration on endothelins, their receptors and endothelin-converting enzyme in rat seminal vesicle. BJU Int 92: 803-809
-
(2003)
BJU Int
, vol.92
, pp. 803-809
-
-
Takahashi, W.1
-
70
-
-
0042731879
-
Elevated serum progastrin-releasing peptide (31-98) level is a predictor of short response duration after hormonal therapy in metastatic prostate cancer
-
Yashi M et al. (2003) Elevated serum progastrin-releasing peptide (31-98) level is a predictor of short response duration after hormonal therapy in metastatic prostate cancer. Prostate 56: 305-312
-
(2003)
Prostate
, vol.56
, pp. 305-312
-
-
Yashi, M.1
-
71
-
-
0038079838
-
Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells
-
Levine L et al. (2003) Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. Cancer Res 63: 3495-3502
-
(2003)
Cancer Res
, vol.63
, pp. 3495-3502
-
-
Levine, L.1
-
72
-
-
33645971015
-
Androgen deprivation induces human prostate epithelial neuroendocrine differentiation of androgen-sensitive LNCaP cells
-
Yuan TC et al. (2006) Androgen deprivation induces human prostate epithelial neuroendocrine differentiation of androgen-sensitive LNCaP cells. Endocr Relat Cancer 13: 151-167
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 151-167
-
-
Yuan, T.C.1
-
73
-
-
12344252767
-
Neuroendocrine differentiation in prostate cancer: Implications for new treatment modalities
-
Vashchenko N and Abrahamsson PA (2005) Neuroendocrine differentiation in prostate cancer: Implications for new treatment modalities. Eur Urol 47: 147-155
-
(2005)
Eur Urol
, vol.47
, pp. 147-155
-
-
Vashchenko, N.1
Abrahamsson, P.A.2
-
74
-
-
14944356887
-
Vasoactive intestinal peptide induces neuroendocrine differentiation in the LNCaP prostate cancer cell line through PKA, ERK, and P13K
-
Gutierrez-Canas I et al. (2005) Vasoactive intestinal peptide induces neuroendocrine differentiation in the LNCaP prostate cancer cell line through PKA, ERK, and P13K. Prostate 63:44-55
-
(2005)
Prostate
, vol.63
, pp. 44-55
-
-
Gutierrez-Canas, I.1
-
75
-
-
0031683505
-
Expression of cytokines enhancing the osteoclast activity, and parathyroid hormone-related protein in prostatic cancers before and after endocrine therapy: An immunohistochemical study
-
Sugihara A et al. (1998) Expression of cytokines enhancing the osteoclast activity, and parathyroid hormone-related protein in prostatic cancers before and after endocrine therapy: An immunohistochemical study. Oncol Rep 5: 1389-1394
-
(1998)
Oncol Rep
, vol.5
, pp. 1389-1394
-
-
Sugihara, A.1
-
76
-
-
0033883914
-
Cytokine variations in patients with hormone treated prostate cancer
-
Wise GJ et al. (2000) Cytokine variations in patients with hormone treated prostate cancer. J Urol 164: 722-725
-
(2000)
J Urol
, vol.164
, pp. 722-725
-
-
Wise, G.J.1
-
77
-
-
1842434391
-
Interleukin-8 confers androgen-independent growth and migration of LNCaP: Differential effects of tyrosine kinases Src and FAK
-
Lee LF et al. (2004) Interleukin-8 confers androgen-independent growth and migration of LNCaP: Differential effects of tyrosine kinases; Src and FAK. Oncogene 23: 2197-2205
-
(2004)
Oncogene
, vol.23
, pp. 2197-2205
-
-
Lee, L.F.1
-
78
-
-
33746853452
-
Involvement of the TNF-alpha autocrine-paracrine loop, via NF-kappaB and YY1, in the regulation of tumor cell resistance to Fas-induced apoptosis
-
Huerta-Yepez S et al. (2006) Involvement of the TNF-alpha autocrine-paracrine loop, via NF-kappaB and YY1, in the regulation of tumor cell resistance to Fas-induced apoptosis. Clin Immunol 120: 297-309
-
(2006)
Clin Immunol
, vol.120
, pp. 297-309
-
-
Huerta-Yepez, S.1
-
79
-
-
29944442302
-
Targeting apoptosis in prostate cancer: Focus on caspases and inhibitors of apoptosis proteins
-
Watson RW and Fitzpatrick JM (2005) Targeting apoptosis in prostate cancer: Focus on caspases and inhibitors of apoptosis proteins. BJU Int 96 (Suppl 2): 30-34
-
(2005)
BJU Int
, vol.96
, Issue.SUPPL. 2
, pp. 30-34
-
-
Watson, R.W.1
Fitzpatrick, J.M.2
-
80
-
-
0032935293
-
Amplification of the androgen receptor gene is associated with P53 mutation in hormone-refractory recurrent prostate cancer
-
Koivisto PA and Rantala I (1999) Amplification of the androgen receptor gene is associated with P53 mutation in hormone-refractory recurrent prostate cancer. J Pathol 187: 237-241
-
(1999)
J Pathol
, vol.187
, pp. 237-241
-
-
Koivisto, P.A.1
Rantala, I.2
-
81
-
-
0032806788
-
Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines
-
Pflug BR et al. (1999) Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines. Prostate 40: 269-273
-
(1999)
Prostate
, vol.40
, pp. 269-273
-
-
Pflug, B.R.1
-
82
-
-
0038724824
-
The role of integrin-linked kinase (ILK) in cancer progression
-
Persad S and Dedhar S (2003) The role of integrin-linked kinase (ILK) in cancer progression. Cancer Metastasis Rev 22: 375-384
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 375-384
-
-
Persad, S.1
Dedhar, S.2
-
83
-
-
24044492845
-
Inhibition of the Akt, cyclooxygenase-2, and matrix metalloproteinase-9 pathways in combination with androgen deprivation therapy: Potential therapeutic approaches for prostate cancer
-
Miyamoto H et al. (2005) Inhibition of the Akt, cyclooxygenase-2, and matrix metalloproteinase-9 pathways in combination with androgen deprivation therapy: Potential therapeutic approaches for prostate cancer. Mol Carcinog 44: 1-10
-
(2005)
Mol Carcinog
, vol.44
, pp. 1-10
-
-
Miyamoto, H.1
-
84
-
-
1642523686
-
Altered expression of syndecan- 1 in prostate cancer
-
Kiviniemi J et al. (2004) Altered expression of syndecan- 1 in prostate cancer. Apmis 112: 89-97
-
(2004)
Apmis
, vol.112
, pp. 89-97
-
-
Kiviniemi, J.1
-
85
-
-
0032864675
-
MMP inhibition in prostate cancer
-
Lokeshwar BL (1999) MMP inhibition in prostate cancer. Ann N Y Acad Sci 878: 271-289
-
(1999)
Ann N Y Acad Sci
, vol.878
, pp. 271-289
-
-
Lokeshwar, B.L.1
-
86
-
-
0142061979
-
The metalloproteinase inhibitor TIMP-2 is down-regulated by androgens in LNCaP prostate carcinoma cells
-
Bratland A et al. (2003) The metalloproteinase inhibitor TIMP-2 is down-regulated by androgens in LNCaP prostate carcinoma cells. Clin Exp Metastasis 20: 541-547
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 541-547
-
-
Bratland, A.1
-
87
-
-
8444231965
-
The influence of androgen deprivation therapy on dihydrotestosterone levels in the prostatic tissue of patients with prostate cancer
-
Nishiyama T et al. (2004) The influence of androgen deprivation therapy on dihydrotestosterone levels in the prostatic tissue of patients with prostate cancer. Clin Cancer Res 10: 7121-7126
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7121-7126
-
-
Nishiyama, T.1
-
88
-
-
33646342738
-
NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss
-
Lei Q et al. (2006) NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell 9: 367-378
-
(2006)
Cancer Cell
, vol.9
, pp. 367-378
-
-
Lei, Q.1
-
89
-
-
27844506524
-
Akt-regulated pathways in prostate cancer
-
Majumder PK and Sellers WR (2005) Akt-regulated pathways in prostate cancer. Oncogene 24: 7465-7474
-
(2005)
Oncogene
, vol.24
, pp. 7465-7474
-
-
Majumder, P.K.1
Sellers, W.R.2
-
90
-
-
5044238301
-
The role of c-Jun and c-Fos expression in androgen-independent prostate cancer
-
Edwards J et al. (2004) The role of c-Jun and c-Fos expression in androgen-independent prostate cancer. J Pathol 204: 153-158
-
(2004)
J Pathol
, vol.204
, pp. 153-158
-
-
Edwards, J.1
-
91
-
-
0030014619
-
Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells
-
Aprikian AG et al. (1996) Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells. J Mol Endocrinol 16: 297-306
-
(1996)
J Mol Endocrinol
, vol.16
, pp. 297-306
-
-
Aprikian, A.G.1
-
92
-
-
0035870258
-
Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway
-
Sumitomo M et al. (2001) Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway. Cancer Res 61: 3294-3298
-
(2001)
Cancer Res
, vol.61
, pp. 3294-3298
-
-
Sumitomo, M.1
-
93
-
-
18844429452
-
In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors
-
Devi GR et al. (2005) In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors. Clin Cancer Res 11: 3930-3938
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3930-3938
-
-
Devi, G.R.1
-
94
-
-
33745563531
-
Celecoxib versus placebo for men with prostate cancer and a rising serum prostate-specific antigen after radical prostatectomy and/or radiation therapy
-
Smith MR et al. (2006) Celecoxib versus placebo for men with prostate cancer and a rising serum prostate-specific antigen after radical prostatectomy and/or radiation therapy. J Clin Oncol 24: 2723-2728
-
(2006)
J Clin Oncol
, vol.24
, pp. 2723-2728
-
-
Smith, M.R.1
-
95
-
-
0038625360
-
Cyclooxygenase-2 as a potential target in the prevention and treatment of genitourinary tumors: A review
-
Pruthi RS et al. (2003) Cyclooxygenase-2 as a potential target in the prevention and treatment of genitourinary tumors: A review. J Urol 189: 2352-2359
-
(2003)
J Urol
, vol.189
, pp. 2352-2359
-
-
Pruthi, R.S.1
-
96
-
-
3242758854
-
Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R)
-
Ling MT et al. (2004) Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R). Carcinogenesis 25: 517-525
-
(2004)
Carcinogenesis
, vol.25
, pp. 517-525
-
-
Ling, M.T.1
-
97
-
-
1542615071
-
Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence
-
Ettinger SL et al. (2004) Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence. Cancer Res 64: 2212-2221
-
(2004)
Cancer Res
, vol.64
, pp. 2212-2221
-
-
Ettinger, S.L.1
-
98
-
-
21844458728
-
Changes in chromogranin a serum levels during endocrine therapy in metastatic prostate cancer patients
-
discussion 229-230
-
Sasaki T et al. (2005) Changes in chromogranin a serum levels during endocrine therapy in metastatic prostate cancer patients. Eur Urol 48: 224-229; discussion 229-230
-
(2005)
Eur Urol
, vol.48
, pp. 224-229
-
-
Sasaki, T.1
-
99
-
-
0033782372
-
PSP94 expression after androgen deprivation therapy: A comparative study with prostate specific antigen in benign prostate and prostate cancer
-
Imasato Y et al. (2000) PSP94 expression after androgen deprivation therapy: A comparative study with prostate specific antigen in benign prostate and prostate cancer. J Urol 164: 1819-1824
-
(2000)
J Urol
, vol.164
, pp. 1819-1824
-
-
Imasato, Y.1
-
100
-
-
0032746018
-
The utility of tissue transglutaminase as a marker of apoptosis during treatment and progression of prostate cancer
-
Rittmaster RS et al. (1999) The utility of tissue transglutaminase as a marker of apoptosis during treatment and progression of prostate cancer. J Urol 162: 2165-2169
-
(1999)
J Urol
, vol.162
, pp. 2165-2169
-
-
Rittmaster, R.S.1
|