aFGF immunoreactivity in prostate cancer and its co-localization with bFGF and FGF8

Journal of Pathology

Volumn 189, Issue 4, 1999, Pages 564-569

  Dorkin, Trevor J ^c   Robinson, Mary C ^a   Marsh, Colin ^a   Neal, David E ^c   Leung, Hing Y ^b  

^a FREEMAN HOSPITAL   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NONE

Author keywords

Co localization; FGF; Immunoreactivity; PIN; Prostate cancer

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 8; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CANCER STAGING; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SCORING SYSTEM; TISSUE DISTRIBUTION;

AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; NEOPLASM PROTEINS; NEOPLASM STAGING; PROSTATIC HYPERPLASIA; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATIC NEOPLASMS; RNA, MESSENGER;

EID: 0032718180     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199912)189:4<564::AID-PATH480>3.0.CO;2-1     Document Type: Article

References (33)

1. Chamberlain J, Melia J, Moss S, Brown J. Report prepared for the health technology assessment panel of the NHS executive on the diagnosis, management, treatment and costs of prostate cancer in England and Wales. Br J Urol 1997; 79 (Suppl): 1-32.
2. Mason IJ. The ins and outs of fibroblast growth factors. Cell 1994; 78: 547-552.
3. Emoto H, Tagashira S, Mattei MG, et al. Structure and expression of human fibroblast growth factor-10. J Biol Chem 1997; 37: 23 191-23 194.
4. Smallwood PM, Munoz-Sanjuan I, Tong P, et al. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci USA 1996; 93: 9850-9857.
5. McWhirter JR, Goulding M, Weiner JA, Chun J, Murre C. A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. Development 1997; 124: 3221-3232.
6. Miyake A, Konishi M, Martin KH, et al. Structure and expression of a novel member, FGF-16, of the fibroblast growth factor family. Biochem Biophys Res Commun 1998; 243: 148-152.
7. Hoshikawa M, Ohbayashi N, Yonamine A, et al. Structure and expression of a novel fibroblast growth factor, FGF-17, preferentially expressed in the embryonic brain. Biochem Biophys Res Commun 1998; 244: 187-191.
8. Tanaka A, Miyamoto K, Minamino M, et al. Cloning and characterisation of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc Natl Acad Sci U S A 1992; 89: 8928-8932.
9. Payson RA, Canatan H, Chotani MA, et al. Cloning of two novel forms of human acidic fibroblast growth factor (aFGF) mRNA. Nucleic Acids Res 1993; 21: 489-495.
10. Mansson P, Adams P, Kan M, McKeehan W. Heparin-binding growth factor gene expression and receptor characteristics in normal rat prostate and two transplantable rat prostate tumours. Cancer Res 1989; 49: 2485-2494.
11. Story MT, Livingston B, Baeten L, et al. Cultured human prostate-derived fibroblasts produce a factor that stimulates their growth with properties indistinguishable from basic fibroblast growth factor. Prostate 1989; 15: 355-365.
12. Ittman M, Mansukhani A. Expression of fibroblast growth factors (FGFs) and FGF receptors in human prostate. J Urol 1997; 157: 351-356.
13. Cronauer MV, Hittmair A, Eder IE, et al. Basic fibroblast growth factor levels in cancer cells and in sera of patients suffering from proliferative disorders of the prostate. Prostate 1997; 31: 223-233.
14. Nakomoto T, Chang C, Li A, Chodak GW. Basic fibroblast growth factor in human prostate cancer cells. Cancer Res 1992; 52: 571-577.
15. Leung HY, Dickson C, Robson CN, Neal DE. Over-expression of fibroblast growth factor-8 in human prostate cancer. Oncogene 1996; 12: 1833-1835.
16. Dorkin TJ, Robinson MC, Marsh C, Bjartell A, Neal DE, Leung HY. FGF8 overexpression in prostate cancer is associated with decreased patient survival and persists following androgen ablation. Oncogene 1999; 18: 2755-2761.
17. Partanen J, Vainikka S, Korhonen J, Armstrong E, Alitalo K. Diverse receptors for fibroblast growth factors. Prog Growth Factor Res 1992; 4: 69-83.
18. Miki T, Bottaro DP, Fleming TP, et al. Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci U S A 1992; 89: 246-250.
19. MacArthur CA, Lawshe A, Xu A, et al. FGF-8 isoforms activate receptor splice variants that are expressed in mesenchymal regions of mouse development. Development 1995; 121: 3603-3613.
20. Cauchi J, Alcorn D, Cancilla B, et al. Light-microscopic immunolocalisation of fibroblast growth factor-1 and -2 in adult rat kidney. Cell Tissue Res 1996; 285: 179-187.
21. El-Hariry I, Pignatelli M, Lemoine N. Fibroblast growth factor 1 and fibroblast growth factor 2 immunoreactivity in gastrointestinal tumours. J Pathol 1997; 181: 39-45.
22. Yamanaka Y, Freiss H, Buchler M, et al. Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumour stage. Cancer Res 1993; 53: 5289-5296.
23. Jouanneau J, Moens G, Bourgeois Y, Poupon MF, Thiery JP. A minority of carcinoma cells producing acidic fibroblast growth factor induces a community effect on tumour progression. Proc Natl Acad Sci U S A 1994; 91: 286-290.
24. Qian J, Bostwick DG, Takahashi S, et al. Chromosomal anomalies in prostate intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridisation. Cancer Res 1995; 55: 5408-5414.
25. Myers RB, Srivastava S, Oeslschlager DK, Grizzle WE. Expression of p160erbB-3 and p185erB-2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma. J Natl Cancer Inst 1994; 86: 1140-1145.
26. Deshmukh N, Scotson J, Dodson AR, Smith PH, Ke Y, Foster CS. Differential expression of acidic and basic fibroblast growth factors in benign prostatic hyperplasia identified by immunohistochemistry. Br J Urol 1997; 80: 869-874.
27. Czubayko F, Smith RV, Chung HC, Wellstein A. Tumour growth and angiogenesis induced by a secreted binding protein for fibroblast growth factors. J Biol Chem 1994; 269: 28 243-28 248.
28. Tanaka A, Furuya A, Yamasaki M, et al. High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralising monoclonal antibody against FGF8. Cancer Res 1998; 58: 2053-2056.
29. Biesiada E, Razandi M, Levin ER. Egr-1 activates basic fibroblast growth factor transcription. J Biol Chem 1996; 271: 18 576-18 581.
30. Wang D, Mayo MW, Baldwin AS Jr. Basic fibroblast growth factor transcriptional autoregulation requires EGR-1. Oncogene 1997; 14: 2291-2299.
31. Lee YJ, Galoforo SS, Berns CM, et al. Effect of ionizing radiation on AP-1 binding activity and basic fibroblast growth factor gene expression in drug-sensitive human breast carcinoma MCF-7 and multidrug-resistant MCF-7/ADR cells. J Biol Chem 1995; 270: 28 790-28 796.
32. Myers RL, Payson RA, Chotani MA, Deaven LL, Chiu I-M. Gene structure and differential expression of acidic fibroblast growth factor mRNA: identification and distribution of four different transcripts. Oncogene 1993; 8: 341-349.
33. Chotani MA, Payson RA, Winkles JA, Chiu I-M. Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester. Nucleic Acids Res 1995; 23: 434-441.