Electrophysiological characterization of left ventricular myocytes from obese Srague-Dwley rat

Obesity

Volumn 14, Issue 5, 2006, Pages 778-786

  Ricci, Estelle ^a   Smallwood, Sébastien ^a   Chouabe, Christophe ^a   Mertani, Hichem C ^a   Raccurt, Mireille ^a   Morel, Gérard ^a   Bonvallet, Robert ^a  

^a CNRS   (France)

Author keywords

Cardiac ionic currents; Diet induced obesity; Leptin receptors

Indexed keywords

ANIMALIA; RATTUS;

CELL SURFACE RECEPTOR; LEPTIN; LEPTIN RECEPTOR;

ANIMAL; ARTICLE; BODY WEIGHT; CELL MEMBRANE POTENTIAL; CELL SIZE; CYTOLOGY; DRUG EFFECT; ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART VENTRICLE; MALE; METABOLISM; OBESITY; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; ADIPOSITY; ANIMALS; BODY WEIGHT; CELL SIZE; ELECTROPHYSIOLOGY; HEART VENTRICLES; LEPTIN; MALE; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; OBESITY; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE;

EID: 33846877618     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2006.90     Document Type: Article

References (24)

1. Kopelman PG. Obesity as a medical problem. Nature. 2000;404:635-43.
2. Barouch LA, Berkowitz DE, Harrison RW, O'Donnell CP, Hare JM. Disruption of leptin signaling to cardiac hypertrophy independently of body weight in mice. Circulation. 2003;108:754-9.
3. Zhang R, Reisin E. Obesity-hypertension: the effects on cardiovascular and renal systems. AJH. 2000;13:1308-14.
4. Ricci MR, Levin BE. Ontogeny of diet-induced obesity in selectivity bred Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol. 2003;285:R610-8.
5. Levin BE, Finnegan M, Triscari J, Sullivan AC. Brown adipose and metabolic features of chronic diet-induced obesity. Am J Physiol. 1985;248:R717-23.
6. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372:425-32.
7. Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med. 1995;1:1311-4.
8. Purdham DM, Zou MX, Rajapurohitam V, Karmazyn M. Rat heart is a site of leptin production and action. Am J Physiol. 2004;287:H2877-84.
9. Shek EW, Brands MW, Hall JE. Chronic leptin infusion increases arterial pressure. Hypertension. 1998;31:409-14.
10. Henriksen JH, Holst JJ, Moller S, Andersen UB, Bendtsen F, Jensen G. Elevated circulating leptin levels in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin. Clin Sci. 2000;99:527-34.
11. Levin BE, Hogan S, Sullivan AC. Initiation and perpetuation of obesity and obesity resistance in rats. Am J Physiol. 1989;256:R766-71.
12. Li H, Matheny M, Tumer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression. Am J Physiol. 1998;275:E405-11.
13. Chouabe C, Espinosa L, Megas P, et al. Reduction of I(Ca,L) and I(to1) density in hypertrophied right ventricular cells by simulated high altitude in adult rats. J Mol Cell Cardiol. 1997;29:193-206.
14. Nickola MW, Wold LE, Colligan PB, Wang G-J, Samson WK, Ren J. Leptin attenuates cardiac contraction in rat ventricular myocytes: role of NO. Hypertension. 2000;36:501-5.
15. Espinosa L, Chouabe C, Morales A, et al. Increased sodium-calcium exchange current in right ventricular cell hypertrophy induced by simulated high altitude in adult rats. J Mol Cell Cardiol. 2000;32:639-53.
16. Levin BE, Triscari J, Sullivan C. Relationship between sympathetic activity and diet-induced obesity in two rat strains. Am J Physiol. 1983;245:R364-71.
17. Rajapurohitam V, Gan XT, Kirshenbaum LA, Karmazyn M. The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes. Circ Res. 2003;93:277-9.
18. Tajmir P, Ceddia RB, Li R-K, Coe IR, Sweeney G. Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase- and phosphatidylinositol 3-kinase-dependent signaling pathways. Endocrinology. 2004;145:1550-5.
19. Jang I, Hwang D, Lee J, et al. Physiological difference between dietary obesity-susceptible and obesity-resistant Sprague Dawley rats in response to moderate high fat diet. Exp Anim. 2003;52:99-107.
20. 2+ current. Hypertension. 2000;35:832-7.
21. Janvier NC, Boyett MR. The role of Na-Ca exchange in the cardiac action potential. Cardiovasc Res. 1996;32:69-84.
22. Calegari VC, Bezerra RM, Torsoni MA, et al. Suppressor of cytokine signaling 3 is induced by angiotensin II in heart and isolated cardiomyocytes, and participates in desensitization. Endocrinology. 2003;144:4586-96.
23. Blaustein MP, Lederer WJ. Sodium/calcium exchange: its physiological implications. Physiol Rev. 1999;79:763-854.
24. Volders PGA, Vos MA, Szabo B, et al. Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts. Cardiovasc Res. 2000;46:376-92.