Retroviral microarray-based platform on nanostructured TiO2 for functional genomics and drug discovery

Biomaterials

Volumn 28, Issue 13, 2007, Pages 2244-2253

  Carbone, Roberta ^a   Giorgetti, Luca ^b,d   Zanardi, Andrea ^a   Marangi, Ida ^b   Chierici, Elisabetta ^a   Bongiorno, Gero ^d   Fiorentini, Francesca ^d   Faretta, Mario ^b   Piseri, Paolo ^d   Pelicci, Pier Giuseppe ^b,c   Milani, Paolo ^d  

^a Via Franco Russoli 3   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Cell based microarrays; Nanostructured titanium oxide

Indexed keywords

CELLS; DRUG PRODUCTS; GENES; RNA; TITANIUM OXIDES; TUMORS; VIRUSES;

CELL-BASED MICROARRAYS; COMPLEX PHENOTYPES; REVERSE INFECTION;

NANOSTRUCTURED MATERIALS;

GLASS; GREEN FLUORESCENT PROTEIN; NANOMATERIAL; RETROVIRUS VECTOR; TITANIUM DIOXIDE;

ARTICLE; CANCER CELL; CELL GROWTH; CONTROLLED STUDY; FILM; FUNCTIONAL GENOMICS; GENE OVEREXPRESSION; GENETIC SCREENING; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; RETROVIRUS INFECTION; RNA INTERFERENCE; VALIDATION PROCESS;

ANIMALS; BIOTINYLATION; DRUG DESIGN; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; RETROVIRIDAE; RNA INTERFERENCE; STREPTAVIDIN; TITANIUM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33846865789     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.12.026     Document Type: Article

References (43)

1. Bailey S.N., Ali S.M., Carpenter A.E., Higgins C.O., and Sabatini D.M. Microarrays of lentiviruses for gene function screens in immortalized and primary cells. Nat Methods 3 2 (2006) 117-122
2. Wheeler D.B., Carpenter A.E., and Sabatini D.M. Cell microarrays and RNA interference chip away at gene function. Nat Genet 37 Suppl (2005) S25-S30
3. Wheeler D.B., Bailey S.N., Guertin D.A., Carpenter A.E., Higgins C.O., and Sabatini D.M. RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells. Nat Methods 1 2 (2004) 127-132
4. Ziauddin J., and Sabatini D.M. Microarrays of cells expressing defined cDNAs. Nature 411 6833 (2001) 107-110
5. Wu R.Z., Bailey S.N., and Sabatini D.M. Cell-biological applications of transfected-cell microarrays. Trends Cell Biol 12 10 (2002) 485-488
6. Bailey S.N., Wu R.Z., and Sabatini D.M. Applications of transfected cell microarrays in high-throughput drug discovery. Drug Discov Today 7 Suppl 18 (2002) S113-S118
7. Arlt D., Huber W., Liebel U., Schmidt C., Majety M., Sauermann M., et al. Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle. Cancer Res 65 17 (2005) 7733-7742
8. Gunsalus K.C., and Piano F. RNAi as a tool to study cell biology: building the genome-phenome bridge. Curr Opin Cell Biol 17 1 (2005) 3-8
9. Chanda S.K., and Caldwell J.S. Fulfilling the promise: drug discovery in the post-genomic era. Drug Discov Today 8 4 (2003) 168-174
10. Hart C.P. Finding the target after screening the phenotype. Drug Discov Today 10 7 (2005) 513-519
11. Echeverri C.J., and Perrimon N. High-throughput RNAi screening in cultured cells: a user's guide. Nat Rev Genet 7 5 (2006) 373-384
12. Hook A.L., Thissen H., and Voelcker N.H. Surface manipulation of biomolecules for cell microarray applications. Trends Biotechnol 24 10 (2006) 471-477
13. Falconnet D., Csucs G., Michelle Grandin H., and Textor M. Surface engineering approaches to micropattern surfaces for cell-based assays. Biomaterials 27 16 (2006) 3044-3063
14. Bhadriraju K., and Chen C.S. Engineering cellular microenvironments to improve cell-based drug testing. Drug Discov Today 7 11 (2002) 612-620
15. Hubbell J.A. Materials as morphogenetic guides in tissue engineering. Curr Opin Biotechnol 14 5 (2003) 551-558
16. Stevens M.M., and George J.H. Exploring and engineering the cell surface interface. Science 310 5751 (2005) 1135-1138
17. Haouzi D., Baghdiguian S., Granier G., Travo P., Mangeat P., and Hibner U. Three-dimensional polarization sensitizes hepatocytes to Fas/CD95 apoptotic signalling. J Cell Sci 118 Pt 12 (2005) 2763-2773
18. 2 with primary and cancer cells. Biomaterials 27 17 (2006) 3221-3229
19. Kuznetsov Y.G., Victoria J.G., Low A., Robinson Jr. W.E., Fan H., and McPherson A. Atomic force microscopy imaging of retroviruses: human immunodeficiency virus and murine leukemia virus. Scanning 26 5 (2004) 209-216
20. Raspanti M., Protasoni M., Manelli A., Guizzardi S., Mantovani V., and Sala A. The extracellular matrix of the human aortic wall: ultrastructural observations by FEG-SEM and by tapping-mode AFM. Micron 37 1 (2006) 81-86
21. Dimitrijevic N.M., Saponjic Z.V., Rabatic B.M., and Rajh T. Assembly and charge transfer in hybrid TiO(2) architectures using biotin-avidin as a connector. J Am Chem Soc 127 5 (2005) 1344-1345
22. Rajh T., Chen L.X., Lukas K., Liu T., Thurnauer M.C., and Tiede D.M. Surface restructuring of nanoparticles: an efficient route for ligand-metal oxide crosstalk. J Phys Chem B 106 (2002) 10543
23. 2 electrodes. J Phys Chem B 108 (2004) 15077-15083
24. Grignani F., Kinsella T., Mencarelli A., Valtieri M., Riganelli D., Grignani F., et al. High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. Cancer Res 58 1 (1998) 14-19
25. Hughes C., Galea-Lauri J., Farzaneh F., and Darling D. Streptavidin paramagnetic particles provide a choice of three affinity-based capture and magnetic concentration strategies for retroviral vectors. Mol Ther 3 4 (2001) 623-630
26. Barborini E., Piseri P., and P M. A pulsed microplasma source of high intensity supersonic carbon cluster beams. J Phys D: Appl Phys 32 (1999) L105-L109
27. 2 by aerodynamically filtered cluster deposition. App Phys Lett 81 (2002) 3052-3054
28. Piseri P., Vahedi-Tafreshi H., and Milani P. Manipulation of nanoparticles in supersonic beams for the production of nanostructured materials. Curr Op Solid State Mater Sci 8 (2004) 195-202
29. 2 under thermal annealing. Nanotechnology 14 11 (2003) 1168-1173
30. Mazza T., Barborini E., Kholmanov I.N., Piseri P., Bongiorno G., Vinati S., et al. Libraries of cluster-assembled titania films for chemical sensing. Appl Phys Lett 87 (2005) 103-108
31. 2 oxide. J Appl Phys 75 (1994) 2845-2951
32. de la Garza L., Saponjic Z.V., Dimitrijevic N.M., Thurnauer M.C., and Rajh T. Surface states of titanium dioxide nanoparticles modified with enediol ligands. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys 110 2 (2006) 680-686
33. Wallin M., Loving R., Ekstrom M., Li K., and Garoff H. Kinetic analyses of the surface-transmembrane disulfide bond isomerization-controlled fusion activation pathway in Moloney murine leukemia virus. J Virol 79 22 (2005) 13856-13864
34. Silva J.M., Mizuno H., Brady A., Lucito R., and Hannon G.J. RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. Proc Natl Acad Sci USA 101 17 (2004) 6548-6552
35. Cullen L.M., and Arndt G.M. Genome-wide screening for gene function using RNAi in mammalian cells. Immunol Cell Biol 83 3 (2005) 217-223
36. Willingham A.T., Deveraux Q.L., Hampton G.M., and Aza-Blanc P. RNAi and HTS: exploring cancer by systematic loss-of-function. Oncogene 23 51 (2004) 8392-8400
37. Harris S.L., and Levine A.J. The p53 pathway: positive and negative feedback loops. Oncogene 24 17 (2005) 2899-2908
38. Lu X. p53: a heavily dictated dictator of life and death. Curr Opin Genet Dev 15 1 (2005) 27-33
39. Bode A.M., and Dong Z. Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 4 10 (2004) 793-805
40. Gomez-Lazaro M., Fernandez-Gomez F.J., and Jordan J. p53: twenty five years understanding the mechanism of genome protection. J Physiol Biochem 60 4 (2004) 287-307
41. Turenne G.A., Paul P., Laflair L., and Price B.D. Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53. Oncogene 20 37 (2001) 5100-5110
42. Agarwal M.L., Agarwal A., Taylor W.R., and Stark G.R. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci USA 92 18 (1995) 8493-8497
43. Baus F., Gire V., Fisher D., Piette J., and Dulic V. Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts. EMBO J 22 15 (2003) 3992-4002