Ambient temperature synthesis of high enantiopurity N-protected peptidyl ketones by peptidyl thiol ester-boronic acid cross-coupling

Journal of the American Chemical Society

Volumn 129, Issue 5, 2007, Pages 1132-1140

  Yang, Hao ^a   Li, Hao ^a   Wittenberg, Rüdiger ^a,b   Egi, Masahiro ^a,c   Huang, Wenwei ^a,d   Liebeskind, Lanny S ^a  

^a EMORY UNIVERSITY   (United States)

^b DS Chemie GmbH   (Germany)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ESTERS; HIGH TEMPERATURE EFFECTS; STOICHIOMETRY; SYNTHESIS (CHEMICAL);

ALKENYL BORONIC ACIDS; AMBIENT TEMPERATURE SYNTHESIS; PEPTIDYL KETONE SYNTHESIS;

KETONES;

ALKENYL GROUP; BORONIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; DIPEPTIDE DERIVATIVE; KETONE DERIVATIVE; PALLADIUM COMPLEX; PEPTIDE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; THIOESTER; THIOPHENE; TRIPEPTIDE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CROSS COUPLING REACTION; DECARBONYLATION; ELIMINATION REACTION; ENANTIOMER; QUANTUM YIELD; REACTION ANALYSIS; ROOM TEMPERATURE; SYNTHESIS;

BORONIC ACIDS; CATALYSIS; CROSS-LINKING REAGENTS; ESTERS; KETONES; LIGANDS; MOLECULAR STRUCTURE; PALLADIUM; PEPTIDES; PHOSPHITES; STEREOISOMERISM; SULFHYDRYL COMPOUNDS; TEMPERATURE;

EID: 33846850351     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0658719     Document Type: Article

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