Therapeutic Chlamydophila abortus and C. pecorum vaccination transiently reduces bovine mastitis associated with Chlamydophila infection

Infection and Immunity

Volumn 75, Issue 2, 2007, Pages 870-877

  Biesenkamp Uhe, Carolin ^a   Li, Yihang ^b   Hehnen, Hans Robert ^a   Sachse, Konrad ^c   Kaltenboeck, Bernhard ^b  

^a BAYER PHARMA AG   (Germany)

^b AUBURN UNIVERSITY   (United States)

^c FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHLAMYDOPHILA VACCINE; IMMUNOLOGICAL ADJUVANT; INACTIVATED VACCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; BACTERIAL INFECTION; CATTLE DISEASE; CHLAMYDOPHILA; CHLAMYDOPHILA ABORTUS; CHLAMYDOPHILA PECORUM; COHORT ANALYSIS; CONTROLLED STUDY; DAIRY CATTLE; IMMUNE RESPONSE; MASTITIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOMATIC CELL; VACCINATION;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; CATTLE; CHLAMYDOPHILA; CHLAMYDOPHILA INFECTIONS; DNA, BACTERIAL; MASTITIS, BOVINE; MILK; POLYMERASE CHAIN REACTION;

EID: 33846840543     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00691-06     Document Type: Article

References (61)

1. Bowen, R. A., P. Spears, J. Storz, and G. E. Seidel, Jr. 1978. Mechanisms of infertility in genital tract infections due to Chlamydia psittaci transmitted through contaminated semen. J. Infect. Dis. 138:95-98.
2. Campbell, L. A., C. C. Kuo, and J. T. Grayston. 1998. Chlamydia pneumoniae and cardiovascular disease. Emerg. Infect. Dis. 4:571-579.
3. Caro, Maria, R., N. Ortega, A. J. Buendia, M. C. Gallego, L. D. Rio, F. Cuello, and J. Salinas. 2003. Relationship between the immune response and protection conferred by new designed inactivated vaccines against ovine enzootic abortion in a mouse model. Vaccine 21:3126-3136.
4. Cavirani, S., C. S. Cabassi, G. Donofrio, B. De Iaco, S. Taddei, and C. F. Flammini. 2001. Association between Chlamydia psittaci seropositivity and abortion in Italian dairy cows. Prev. Vet. Med. 50:145-151.
5. Christiansen, G., and S. Birkelund. 2002. Is a Chlamydia vaccine a reality? Best. Pract. Res. Clin. Obstet. Gynecol. 16:889-900.
6. Corner, A. H., G. L. Bannister, and D. P. Hill. 1968. A histological study on the effects of enzootic abortion of ewes virus in the lactating bovine mammary gland. Can. J. Comp. Med. Vet. Sci. 32:259-268.
7. Cox, J. C., and A. R. Coulter. 1997. Adjuvants - a classification and review of their modes of action. Vaccine 15:248-256.
8. Danesh, J., R. Collins, and R. Peto. 1997. Chronic infections and coronary heart disease: is there a link? Lancet 350:430-436.
9. DeGraves, F. J., D. Gao, H. R. Hehnen, T. Schlapp, and B. Kaltenboeck. 2003. Quantitative detection of Chlamydia psittaci and C. pecorum by high-sensitivity real-time PCR reveals high prevalence of vaginal infection in cattle. J. Clin. Microbiol. 41:1726-1729.
10. DeGraves, F. J., D. Gao, and B. Kaltenboeck. 2003. High-sensitivity quantitative PCR platform. BioTechniques 34:106-115.
11. DeGraves, F. J., T. Kim, J. Jee, T. Schlapp, H. R. Hehnen, and B. Kaltenboeck. 2004. Reinfection with Chlamydophila abortus by uterine and indirect cohort routes reduces fertility in cattle preexposed to Chlamydophila. Infect. Immun. 72:2538-2545.
12. Dinsmore, R. P., P. B. English, R. N. Gonzalez, and P. M. Sears. 1992. Use of augmented cultural techniques in the diagnosis of the bacterial cause of clinical bovine mastitis. J. Dairy Sci. 75:2706-2712.
13. Dohoo, I. R., and K. E. Leslie. 1991. Evaluation of changes in somatic cell counts as indicators of new intramammary infections. Prev. Vet. Med. 10:225-233.
14. Dohoo, I., W. Martin, and H. Stryhn. 2003. Veterinary epidemiologic research. AVC Inc., Prince Edward Island, Canada.
15. Edmondson, A. J., I. J. Lean, L. D. Weaver, T. Farver, and G. Webster. 1989. A body condition scoring chart for Holstein dairy cows. J. Dairy Sci. 72:68-78.
16. Erskine, R. J. 2001. Mastitis control in dairy herds, p. 397-433. In O. M. Radostits (ed.), Herd health: food animal production medicine, 3rd ed. W. B. Saunders Co., Philadelphia, PA.
17. Everett, K. D., R. M. Bush, and A. A. Andersen. 1999. Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int. J. Syst. Bacteriol. 49:415-440.
18. Green, M. J., L. E. Green, Y. H. Schukken, A. J. Bradley, E. J. Peeler, H. W. Barkema, Y. de Haas, V. J. Collins, and G. F. Medley, 2004. Somatic cell count distributions during lactation predict clinical mastitis. J. Dairy Sci. 87:1256-1264.
19. Griffiths, P. C., J. M. Plater, T. C. Martin, S. L. Hughes, K. J. Hughes, R. G. Hewinson, and M. Dawson. 1995. Epizootic bovine abortion in a dairy herd: characterization of a Chlamydia psittaci isolate and antibody response. Br. Vet. J. 151:683-693.
20. Hilleman., M. 2004. Strategies and mechanisms for host and pathogen survival in acute and persistent viral infections. Proc. Natl. Acad. Sci. USA 101:(Suppl. 2)14560-14566.
21. Huang, J., M. D. Wang, S. Lenz, D. Gao, and B. Kaltenboeck. 1999. IL-12 administered during Chlamydia psittaci lung infection in mice confers immediate and long-term protection and reduces macrophage inflammatory protein-2 level and neutrophil infiltration in lung tissue. J. Immunol. 162:2217-2226.
22. Igietseme, J. U., F. O. Eko, and C. M. Black. 2003. Contemporary approaches to designing and evaluating vaccine against Chlamydia. Expert Rev. Vaccines 2:129-146.
23. Ioannou, X. P., S. M. Gomis, B. Karvonen, R. Hecker, L. A. Babiuk, and S. van Drunen Littel-van den Hurk. 2002. CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune responses to a herpesvirus glycoprotein. Vaccine 21:127-137.
24. Jee, J., F. J. DeGraves, T. Kim, and B. Kaltenboeck. 2004. High prevalence of natural Chlamydophila spp. infection in calves. J. Clin. Microbiol. 42:5664-5672.
25. Kaltenboeck, B., D. Heard, F. J. DeGraves, and N. Schmeer. 1997. Use of synthetic antigens improves detection by enzyme-linked immunosorbent assay of antibodies against abortigenic Chlamydia psittaci in ruminants. J. Clin. Microbiol. 35:2293-2298.
26. Kaltenboeck, B., K. G. Kousoulas, and J. Storz. 1992. Two-step polymerase chain reactions and restriction endonuclease analyses detect and differentiate ompA DNA of Chlamydia spp. J. Clin. Microbiol. 30:1098-1104.
27. Kaltenboeck, B., N. Schmeer, and R. Schneider. 1997. Evidence for numerous omp1 alleles of porcine Chlamydia trachomatis and novel chlamydial species obtained by PCR. J. Clin. Microbiol. 35:1835-1841.
28. Le Roux, Y., F. Laurent, and F. Moussaoui. 2003. Polymorphonuclear proteolytic activity and milk composition change. Vet. Res. 34:629-645.
29. Li, D., A. Vaglenov, T. Kim, C. Wang, D. Gao, and B. Kaltenboeck. 2005. High yield culture and purification of Chlamydiaceae bacteria. J. Microbiol. Methods 61:17-24.
30. McInerney, T. L., F. R. Brennan, T. D. Jones, and N. J. Dimmock. 1999. Analysis of the ability of five adjuvants to enhance immune responses to a chimeric plant virus displaying an HIV-1 peptide. Vaccine 17:1359-1368.
31. McKercher, D. G., E. M. Wada, E. A. Robinson, and J. A. Howarth. 1966. Epizootiologic and immunologic studies of epizootic bovine abortion. Cornell Vet. 56:433-450.
32. McNutt, S. H., and E. F. Waller. 1940. Sporadic bovine encephalomyelitis. Cornell Vet. 30:437-448.
33. Mecklinger, S., J. Wehr, F. Horsch, and W. Seffner. 1980. Experimental chlamydial mastitis. Wiss. Ztschr. Humboldt-Univ. Berlin Math.-Nat. Sci. R. 29:75-79.
34. Otter, A., D. F. Twomey, N. S. Rowe, J. W. Tipp, W. S. McElligott, P. C. Griffiths, and P. O'Neill. 2003. Suspected chlamydial keratoconjunctivitis in British cattle. Vet. Rec. 152:787-788.
35. Pfützner, H., and K. Sachse. 1996. Mycoplasma bovis as an agent of mastitis, pneumonia, arthritis and genital disorders in cattle. Rev. Sci. Tech. Off. Int. Epizoot. 15:1477-1494.
36. Pyörälä, S. 2003. Indicators of inflammation in the diagnosis of mastitis. Vet. Res. 34:565-578.
37. Quinn, T. C. 1998. Does Chlamydia pneumoniae cause coronary heart disease? Curr. Opin. Infect. Dis. 11:301-307.
38. Rank, R. G. 1999. Models of immunity, p. 239-296. In R. S. Stephens (ed.), Chlamydia: intracellular biology, pathogenesis, and immunity. American Society for Microbiology, Washington, DC.
39. Rønsholt, L., and A. Basse. 1981. Bovine mastitis induced by a common intestinal Chlamydia psittaci strain. A pathogenetic and serological investigation. Acta Vet. Scand. 22:9-22.
40. Sachse, K., and H. Hotzel. 2003. Detection and differentiation of chlamydiae by nested PCR. Methods Mol. Biol. 216:123-136.
41. Saikku, P., M. Leinenen, K. Mattila, M. R. Ekman, M. S. Nieminen, P. H. Makela, J. K. Huttunen, and V. Valtonen. 1988. Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet ii:983-986.
42. Schachter, J. 1999. Infection and disease epidemiology, p. 139-170. In R. S. Stephens (ed.), Chlamydia: intracellular biology, pathogenesis, and immunity. American Society for Microbiology, Washington, DC.
43. Schachter, J., J. Banks, N. Sugg, M. Sung, J. Storz, and K. F. Meyer. 1975. Serotyping of Chlamydia. II. Isolates of bovine origin. Infect. Immun. 11:904-907.
44. Schijns, V. E. J. C. 2003. Mechanisms of vaccine adjuvant activity: initiation and regulation of immune responses by vaccine adjuvants. Vaccine 21:829-831.
45. Schmidt-Madsen, P. 1975. Fluoro-opto-electronic cell counting on milk. J. Dairy Res. 42:227-239.
46. Schroeder, J. W. 1997. Mastitis control programs: bovine mastitis and milking management. North Dakota State University Extension Service Publication AS1129. North Dakota State University, Fargo.
47. Schukken, Y. H., D. J. Wilson, F. Welcome, L. Garrison-Tikovsky, and R. N. Gonzalez. 2003. Monitoring udder health and milk quality using somatic cell counts. Vet. Res. 34:579-596.
48. Seegers, H., C. Fourichon, and F. Beaudeau. 2003. Production effects related to mastitis and mastitis economics in dairy cattle herds. Vet. Res. 34:475-491.
49. Sela, M., and M. Hilleman. 2004. Therapeutic vaccines: realities of today and hopes for tomorrow. Proc. Natl. Acad. Sci. USA 101:(Suppl. 2)14559.
50. Shewen, P. E. 1980. Chlamydial infection in animals. Can. Vet. J. 21:2-11.
51. Spears, P., and J. Storz. 1979. Biotyping of Chlamydia psittaci based on inclusion morphology and response to diethylaminoethyl- dextran and cycloheximide. Infect. Immun. 24:224-232.
52. Stemke-Hale, K., B. Kaltenboeck, F. J. DeGraves, K. F. Sykes, J. Huang, C.-H. Bu, and S. A. Johnston. 2005. Screening the whole genome of a pathogen in vivo for protective antigens. Vaccine 23:3016-3025.
53. Storz, J., E. J. Carroll, L. Ball, and L. C. Faulkner. 1968. Isolation of a psittacosis agent (Chlamydia) from semen and epididymis of bulls with seminal vesiculitis syndrome. Am. J. Vet. Res. 29:549-555.
54. Twomey, D. F., P. C. Griffiths, B. C. Hignett, and T. P. Martin. 2003. Suspected Chlamydial polyarthritis in a calf in the UK. Vet. Rec. 152:340.
55. Wang, F.-I., H. Shieh, and Y.-K. Liao. 2001. Prevalence of Chlamydophua abortus infection in domesticated ruminants in Taiwan. J. Vet. Med. Sci. 63:1215-1220.
56. Ward, M. E. 1999. Mechanisms of chlamydia-induced disease, p. 171-210. In R. S. Stephens (ed.), Chlamydia: intracellular biology, pathogenesis, and immunity. American Society for Microbiology, Washington, DC.
57. Wehnert, C., J. Wehr, G. Teichmann, S. Mecklinger, and W. Zimmerhackel. 1980. Investigations on the contribution of chlamydiae to a mastitis episode. Wiss. Ztschr. Humboldt-Univ. Berlin Math.-Nat. Sci. R. 29:71-73.
58. Wehrend, A., K. Failing, B. Hauser, C. Jäger, and H. Bostedt. 2005. Production, reproductive, and metabolic factors associated with chlamydial seropositivity and reproductive tract antigens in dairy herds with fertility disorders. Theriogenology 63:923-930.
59. White, G. 1965. Experimental production of pneumonia in calves by infection with an organism of the psittacosis-lymphogranuloma group. Vet. Rec. 77:1124-1126.
60. Wilson, M. R., and R. G. Thomson. 1968. Chlamydia pneumonia of calves. Res. Vet. Sci. 9:467-473.
61. Wittenbrink, M. M., H. A. Schoon, D. Schoon, R. Mansfeld, and W. Bisping. 1993. Endometritis in cattle experimentally induced by Chlamydia psittaci. J. Vet. Med. B. 40:437-450.