A physiologically based pharmacokinetic model for lactational transfer of PCB 153 with or without PCB 126 in mice

Archives of Toxicology

Volumn 81, Issue 2, 2007, Pages 101-111

  Lee, Sun Ku ^a,b   Ou, Ying C ^a,c   Andersen, Melvin E ^a,d   Yang, Raymond S H ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

^c ALZA CORPORATION   (United States)

^d CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

Lactational transfer; PBPK; PCB; Pharmacokinetic interaction; Risk assessment

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; VERY LOW DENSITY LIPOPROTEIN;

ADIPOSE TISSUE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BLOOD VOLUME; BREAST; CHEMICAL BINDING; CONTROLLED STUDY; LACTATION; LIPID TRANSPORT; MAMMARY GLAND; MODEL; MOUSE; NEWBORN; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICOKINETICS;

ANIMALS; ANIMALS, SUCKLING; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; ENVIRONMENTAL POLLUTANTS; FEMALE; LACTATION; LIPOPROTEINS, VLDL; MAMMARY GLANDS, ANIMAL; MICE; MODELS, BIOLOGICAL; POLYCHLORINATED BIPHENYLS; RISK ASSESSMENT;

MUS; RODENTIA;

EID: 33846826601     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-006-0130-0     Document Type: Article

References (45)

1. Anderson HA, Falk C, Hanrahan L, Olson J, Burse VW, Needham L, Paschal D, Patterson D Jr, Hill RH Jr (1998) Profiles of Great Lakes critical pollutants: a sentinel analysis of human blood and urine. The Great Lakes Consortium. Environ Health Perspect 106:279-289
2. Birnbaum LS, Weber H, Harris MW, Lamb JC, McKinney JD (1985) Toxic interaction of specific polychlorinated biphenyls and 2,3,7,8- tetrachlorodibenzo-p-dioxin: increased incidence of cleft palate in mice. Toxicol Appl Pharmacol 77:292-302
3. Borlakoglu JT, Clarke S, Huang SW, Dils RR, Haegele KD, Gibson GG (1992) Lactational transfer of 3,3′,4,4′-tetrachloro-and 2,2′,4,4′,5,5′-hexachlorobiphenyl induces cytochrome P450IVA1 in neonates. Evidence for a potential synergistic mechanism. Biochem Pharmacol 43:153-157
4. Brown RP, Delp MD, Lindstedt SL, Rhomberg LR, Beliles RP (1997) Physiological parameter values for physiologically based pharmacokinetic models. Toxicol Ind Health 13:407-484
5. Buck GM (1996) Epidemiologic perspective of the developmental neurotoxicity of PCBs in humans. Neurotoxicol Teratol 18:239-241; discussion 271-236
6. Carpenter DO (1998) Polychlorinated biphenyls and human health. Int J Occup Med Environ Health 11:291-303
7. Clewell RA, Gearhart JM (2002) Pharmacokinetics of toxic chemicals in breast milk: use of PBPK models to predict infant exposure. Environ Health Perspect 110:A333-A337
8. Corley RA, Mast TJ, Carney EW, Rogers JM, Daston GP (2003) Evaluation of physiologically based models of pregnancy and lactation for their application in children's health risk assessment. CRC Crit Rev Toxicol 33:137-211
9. De Jongh J, Verhaar HJ, Hermens JL (1997) A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans. Arch Toxicol 72:17-25
10. Fisher JW, Whittaker TA, Taylor DH, Clewell HJ 3rd, Andersen ME (1990) Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloro-acetic acid. Toxicol Appl Pharmacol 102:497-513
11. Gallenberg LA, Ring BJ, Vodicnik MJ (1990) The influence of time of maternal exposure to 2,2′,4,4′,5,5′-hexachlorobiphenyl on its accumulation in their nursing offspring. Toxicol Appl Pharmacol 104:1-8
12. Goldey ES, Kehn LS, Lau C, Rehnberg GL, Crofton KM (1995) Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone concentrations and causes hearing deficits in rats. Toxicol Appl Pharmacol 135:77-88
13. Hansen LG (1998) Stepping backward to improve assessment of PCB congener toxicities. Environ Health Perspect 106(Suppl 1):171-189
14. Hsu ST, Ma CI, Hsu SK, Wu SS, Hsu NH, Yeh CC, Wu SB (1985) Discovery and epidemiology of PCB poisoning in Taiwan: a four-year followup. Environ Health Perspect 59:5-10
15. Huisman M, Koopman-Esseboom C, Fidler V, Hadders-Algra M, van der Paauw CG, Tuinstra LG, Weisglas-Kuperus N, Sauer PJ, Touwen BC, Boersma ER (1995) Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological development. Early Hum Dev 41:111-277
16. Jacobson JL, Jacobson SW, Humphrey HE (1990) Effects of in utero exposure to polychlorinated biphenyls and related contaminants on cognitive functioning in young children. J Pediatr 116:38-455
17. Kafafi SA, Afeefy HY, Ali AH, Said HK, Kafafi AG (1993) Binding of polychlorinated biphenyls to the aryl hydrocarbon receptor. Environ Health Perspect 101:422-428
18. Kedderis LB, Mills JJ, Andersen ME, Birnbaum LS (1993) A physiologically based pharmacokinetic model for TBDD in the rat: tissue distribution and CYP1A induction. Toxicol Appl Pharmacol 121:87-98
19. Koga N, Beppu M, Yoshimura H (1990) Metabolism in vivo of 3,4,5,3′,4′-pentachlorobiphenyl and toxicological assessment of the metabolite in rats. J Pharmacobiodyn 13:497-506
20. Kuratsune M, Yoshimura T, Matsuzaka J, Yamaguchi A (1971) Yusho, a poisoning caused by rice oil contaminated with polychlorinated biphenyls. HSMHA Health Rep 86:1083-1091
21. Landers JP, Bunce NJ (1991) The Ah receptor and the mechanism of dioxin toxicity. Biochem J 276:273-287
22. Lee SK (2005) Perinatal pharmacokinetics. In: Reddy MB, Yang RSH, Clewell HJ, Andersen ME (eds) Physiologically based pharmacokinetic modeling. Wiley, Hoboken, pp. 321-347
23. Lee SK, Ou YC, Yang RSH (2002) Comparison of pharmacokinetic interactions and physiologically based pharmacokinetic modeling of PCB 153 and PCB 126 in nonpregnant mice, lactating mice, and suckling pups. Toxicol Sci 65:26-34
24. Lutz RJ, Dedrick RL, Matthews HB, Eling TE, Anderson MW (1977) A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat. Drug Metab Dispos 5:386-396
25. Lutz RJ, Dedrick RL, Tuey D, Sipes IG, Anderson MW, Matthews HB (1984) Comparison of the pharmacokinetics of several polychlorinated biphenyls in mouse, rat, dog, and monkey by means of a physiological pharmacokinetic model. Drug Metab Dispos 12:527-535
26. Matsumura F (1995) Mechanism of action of dioxin-type chemicals, pesticides, and other xenobiotics affecting nutritional indexes. Am J Clin Nutr 61(Suppl 3):695S-711S
27. Matthews HB, Dedrick RL (1984) Pharmacokinetics of PCBs. Annu Rev Pharmacol Toxicol 24:85-103
28. Mimura J, Fujii-Kuriyama Y (2003) Functional role of AhR in the expression of toxic effects by TCDD. Biochim Biophys Acta 1619:263-268
29. Noren K, Weistrand C, Karpe F (1999) Distribution of PCB congeners, DDE, hexachlorobenzene, and methylsulfonyl metabolites of PCB and DDE among various fractions of human blood plasma. Arch Environ Contam Toxicol 37:408-414
30. Olsen H, Enan E, Matsumura F (1998) TCDD mechanism of action to reduce lipoprotein lipase activity in the 3T3-L1 preadipocyte cell line. J Biochem Mol Toxicol 12:29-39
31. Oskarsson A, Palminger HI, Sundberg J, Petersson GK (1998) Risk assessment in relation to neonatal metal exposure. Analyst 123:19-23
32. Poulin P, Krishnan K (1995a) An algorithm for predicting tissue: blood partition coefficients of organic chemicals from n-octanol: water partition coefficient data. J Toxicol Environ Health 46:117-129
33. Poulin P, Krishnan K (1995b) A biologically-based algorithm for predicting human tissue: blood partition coefficients of organic chemicals. Hum Exp Toxicol 14:273-280
34. Prabhakaran S, Devi KS (1993) Impact of protein deficiency and exposure to hexachlorocyclohexane or malathion on lipid metabolism in pregnant rats. Indian J Biochem Biophys 30:234-238
35. Ring BJ, Seitz KR, Gallenberg LA, Vodicnik MJ (1990) The effect of diet and litter size on the elimination of 2,2′,4,4′,5,5′- hexachlorobiphenyl from lactating mice. Toxicol Appl Pharmacol 104:9-16
36. Ross G (2004) The public health implications of polychlorinated biphenyls (PCBs) in the environment. Ecotoxicol Environ Saf 59:275-291
37. Safe SH (1994) Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit Rev Toxicol 24:87-149
38. Seegal RF, Brosch KO, Okoniewski RJ (1997) Effects of in utero and lactational exposure of the laboratory rat to 2,4,2′,4′-and 3,4,3′,4′-tetrachlorobiphenyl on dopamine function. Toxicol Appl Pharmacol 146:95-103
39. Spindler-Vomachka M, Vodicnik MJ (1984) Distribution of 2,4,5,2′,4′,5′-hexachlorobiphenyl among lipoproteins during pregnancy and lactation in the rat. J Pharmacol Exp Ther 230:263-268
40. Tang C, Lin JH, Lu AYH (2005) Metabolism-based drug-drug interactions: what determines individual variability in cytochrome P450 induction? Drug Metab Dispos 33:603-613
41. Tilson HA, Jacobson JL, Rogan WJ (1990) Polychlorinated biphenyls and the developing nervous system: cross-species comparisons. Neurotoxicol Teratol 12:239-488
42. Tuey DB, Matthews HB (1980) Use of a physiological compartmental model for the rat to describe the pharmacokinetics of several chlorinated biphenyls in the mouse. Drug Metab Dispos 8:397-403
43. Vodicnik MJ, Lech JJ (1980) The transfer of 2,4,5,2′,4′, 5′-hexachlorobiphenyl to fetuses and nursing offspring. I. Disposition in pregnant and lactating mice and accumulation in young. Toxicol Appl Pharmacol 54:293-300
44. Weistrand C, Noren K (1998) Polychlorinated naphthalenes and other organochlorine contaminants in human adipose and liver tissue. J Toxicol Environ Health 53:293-311
45. Wolfle D (1997) Interactions between 2,3,7,8-TCDD and PCBs as tumor promoters: limitations of TEFs. Teratog Carcinog Mutagen 17:217-224