A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue blood partition coefficients of organic chemicals in rats and humans

Archives of Toxicology

Volumn 72, Issue 1, 1997, Pages 17-25

  DeJongh, Joost ^a   Verhaar, Henk J M ^a   Hermens, Joop L M ^a  

^a Research Institute of Toxicology   (Netherlands)

Author keywords

Distribution; Modelling; Partition coefficients; Physiologically based pharmacokinetics (PB PK)

Indexed keywords

ORGANIC COMPOUND; VOLATILE ORGANIC COMPOUND;

ADIPOSE TISSUE; ARTICLE; BLOOD; BRAIN TISSUE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; HUMAN; MODEL; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; TISSUE HOMOGENATE; TOXICOKINETICS;

1-OCTANOL; ADIPOSE TISSUE; ALGORITHMS; ANIMALS; BRAIN CHEMISTRY; HUMANS; HYDROCARBONS; LIVER; MODELS, BIOLOGICAL; MUSCLES; RATS; WATER; XENOBIOTICS;

EID: 0031413080     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050463     Document Type: Article

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