-
1
-
-
0037145037
-
Integrins: bidirectional, allosteric signalling machines
-
Hynes R.O. Integrins: bidirectional, allosteric signalling machines. Cell 110 (2002) 673-687
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
2
-
-
0013264177
-
Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble
-
Humphries M.J., McEwan P.A., Barton S.J., Buckley P.A., Bella J., and Mould A.P. Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble. Trends Biochem. Sci. 28 (2003) 313-320
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 313-320
-
-
Humphries, M.J.1
McEwan, P.A.2
Barton, S.J.3
Buckley, P.A.4
Bella, J.5
Mould, A.P.6
-
4
-
-
0035516140
-
Transmembrane extracellular matrix-cytoskeleton crosstalk
-
Geiger B., Bershadsky A., Pankov R., and Yamada K.M. Transmembrane extracellular matrix-cytoskeleton crosstalk. Nat. Rev. 2 (2001) 793-805
-
(2001)
Nat. Rev.
, vol.2
, pp. 793-805
-
-
Geiger, B.1
Bershadsky, A.2
Pankov, R.3
Yamada, K.M.4
-
5
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin alpha v beta 3 in complex with an Arg-Gly-Asp ligand
-
Xiong J.P., Stehle T., Zhang R., Joachimiak Frech M., Goodman S.L., and Arnaout M.A. Crystal structure of the extracellular segment of integrin alpha v beta 3 in complex with an Arg-Gly-Asp ligand. Science 296 (2002) 151-155
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.P.1
Stehle, T.2
Zhang, R.3
Joachimiak Frech, M.4
Goodman, S.L.5
Arnaout, M.A.6
-
6
-
-
0036696904
-
α4 integrins and the immune response
-
Rose D.M., Han J., and Ginsberg M.H. α4 integrins and the immune response. Immunol. Rev. 186 (2002) 118-124
-
(2002)
Immunol. Rev.
, vol.186
, pp. 118-124
-
-
Rose, D.M.1
Han, J.2
Ginsberg, M.H.3
-
8
-
-
0025161990
-
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
-
Elices M.J., Osborn L., Takada Y., Crouse C., Luhowskyi S., Hemler M.H., and Lobb R.R. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60 (1990) 577-584
-
(1990)
Cell
, vol.60
, pp. 577-584
-
-
Elices, M.J.1
Osborn, L.2
Takada, Y.3
Crouse, C.4
Luhowskyi, S.5
Hemler, M.H.6
Lobb, R.R.7
-
9
-
-
0024418764
-
Identification and characterisation of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin
-
Wayner E.A., Garcia-Pardo A., Humphries M.J., McDonald J.A., and Carter W.G. Identification and characterisation of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. J. Cell Biol. 109 (1989) 1321-1330
-
(1989)
J. Cell Biol.
, vol.109
, pp. 1321-1330
-
-
Wayner, E.A.1
Garcia-Pardo, A.2
Humphries, M.J.3
McDonald, J.A.4
Carter, W.G.5
-
10
-
-
0025219640
-
Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin α4β1
-
Mould A.P., Wheldon L.A., Komoriya A., Wayner E.A., Yamada K.M., and Humphries M.J. Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin α4β1. J. Biol. Chem. 265 (1990) 4020-4024
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 4020-4024
-
-
Mould, A.P.1
Wheldon, L.A.2
Komoriya, A.3
Wayner, E.A.4
Yamada, K.M.5
Humphries, M.J.6
-
11
-
-
0030612147
-
α4 Integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity
-
Newham P., Craig S.E., Seddon G.N., Schofield N.R., Rees A., Edwards R.M., Jones E.Y., and Humphries M.J. α4 Integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity. J. Biol. Chem. 272 (1997) 19429-19440
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19429-19440
-
-
Newham, P.1
Craig, S.E.2
Seddon, G.N.3
Schofield, N.R.4
Rees, A.5
Edwards, R.M.6
Jones, E.Y.7
Humphries, M.J.8
-
13
-
-
0037192934
-
Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior
-
Li Z., Calzada M.J., Sipes J.M., Cashel J.A., Krutzsch H.C., Annis D.S., Mosher D.F., and Roberts D.D. Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior. J. Cell Biol. 157 (2002) 509-519
-
(2002)
J. Cell Biol.
, vol.157
, pp. 509-519
-
-
Li, Z.1
Calzada, M.J.2
Sipes, J.M.3
Cashel, J.A.4
Krutzsch, H.C.5
Annis, D.S.6
Mosher, D.F.7
Roberts, D.D.8
-
14
-
-
0034233562
-
In vivo functions of integrins: lessons from null mutations in mice
-
Sheppard D. In vivo functions of integrins: lessons from null mutations in mice. Matrix Biol. 19 (2000) 203-209
-
(2000)
Matrix Biol.
, vol.19
, pp. 203-209
-
-
Sheppard, D.1
-
15
-
-
0025277242
-
CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes
-
Ferrero E., Hsieh C.-L., Francke U., and Goyert S.M. CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes. J. Immunol. 145 (1990) 331-336
-
(1990)
J. Immunol.
, vol.145
, pp. 331-336
-
-
Ferrero, E.1
Hsieh, C.-L.2
Francke, U.3
Goyert, S.M.4
-
16
-
-
0024555494
-
Monocyte antigen CD14 is a phospholipid anchored membrane protein
-
Simmons D.L., Tan S., Tenen D.G., Nicholson-Weller A., and Seed B. Monocyte antigen CD14 is a phospholipid anchored membrane protein. Blood 73 (1989) 284-289
-
(1989)
Blood
, vol.73
, pp. 284-289
-
-
Simmons, D.L.1
Tan, S.2
Tenen, D.G.3
Nicholson-Weller, A.4
Seed, B.5
-
17
-
-
15744396047
-
Crystal structure of CD14 and its implications for lipopolysaccaride signalling
-
Kim J.-I., Lee C.J., Jin M.S., Lee C.-H., Paik S.-G., Lee H., and Lee J.-O. Crystal structure of CD14 and its implications for lipopolysaccaride signalling. J. Immunol. 280 (2005) 11347-11351
-
(2005)
J. Immunol.
, vol.280
, pp. 11347-11351
-
-
Kim, J.-I.1
Lee, C.J.2
Jin, M.S.3
Lee, C.-H.4
Paik, S.-G.5
Lee, H.6
Lee, J.-O.7
-
18
-
-
0031922269
-
Soluble CD14 activates monocytic cells independently of lipopolysaccharide
-
Landmann R., Link S., Sansano S., Rajacic Z., and Zimmerli W. Soluble CD14 activates monocytic cells independently of lipopolysaccharide. Infect. Immun. 66 (1998) 2264-2271
-
(1998)
Infect. Immun.
, vol.66
, pp. 2264-2271
-
-
Landmann, R.1
Link, S.2
Sansano, S.3
Rajacic, Z.4
Zimmerli, W.5
-
19
-
-
29144458862
-
Time to adandon dogma: CD14 is expressed by non-myeloid lineage cells
-
Jersmann H.P.A. Time to adandon dogma: CD14 is expressed by non-myeloid lineage cells. Immunol. Cell Biol. 83 (2005) 462-467
-
(2005)
Immunol. Cell Biol.
, vol.83
, pp. 462-467
-
-
Jersmann, H.P.A.1
-
20
-
-
33745712626
-
GPI linked endothelial CD14 contributes to the detection of LPS
-
Lloyd K.L., and Kubes P. GPI linked endothelial CD14 contributes to the detection of LPS. Am. J. Physiol. Heart Circ. Physiol. 291 (2006) H473-H481
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.291
-
-
Lloyd, K.L.1
Kubes, P.2
-
21
-
-
0033961977
-
Evaluation of CD14 in host defence
-
Antal-Szalmas P. Evaluation of CD14 in host defence. Eur. J. Clin. Invest. 30 (2000) 167-179
-
(2000)
Eur. J. Clin. Invest.
, vol.30
, pp. 167-179
-
-
Antal-Szalmas, P.1
-
22
-
-
17344374020
-
The dynamics of LPS recognition: complex orchestration of multiple receptors
-
Triantafilou M., and Triantafilou K. The dynamics of LPS recognition: complex orchestration of multiple receptors. J. Endotoxin Res. 11 (2005) 5-11
-
(2005)
J. Endotoxin Res.
, vol.11
, pp. 5-11
-
-
Triantafilou, M.1
Triantafilou, K.2
-
23
-
-
0036606913
-
Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster
-
Triantafilou M., and Triantafilou K. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol. 23 (2002) 301-304
-
(2002)
Trends Immunol.
, vol.23
, pp. 301-304
-
-
Triantafilou, M.1
Triantafilou, K.2
-
24
-
-
0032473968
-
Human CD14 mediated recognition and phagocytosis of apoptotic cells
-
Devitt A., Moffatt O.D., Raykundalia C., Capra J.D., Simmons D.L., and Gregory C.D. Human CD14 mediated recognition and phagocytosis of apoptotic cells. Nature 392 (1998) 505-509
-
(1998)
Nature
, vol.392
, pp. 505-509
-
-
Devitt, A.1
Moffatt, O.D.2
Raykundalia, C.3
Capra, J.D.4
Simmons, D.L.5
Gregory, C.D.6
-
26
-
-
0029932651
-
Integrins as promiscuous signal transduction devices
-
Petty H.R., and Todd R.F. Integrins as promiscuous signal transduction devices. Immunol. Today 17 (1996) 209-212
-
(1996)
Immunol. Today
, vol.17
, pp. 209-212
-
-
Petty, H.R.1
Todd, R.F.2
-
28
-
-
0028944308
-
Identification of a novel ani-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit
-
Mould A.P., Garratt A.N., Askari J.A., Akiyama S.K., and Humphries M.J. Identification of a novel ani-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit. FEBS Lett. 363 (1995) 118-122
-
(1995)
FEBS Lett.
, vol.363
, pp. 118-122
-
-
Mould, A.P.1
Garratt, A.N.2
Askari, J.A.3
Akiyama, S.K.4
Humphries, M.J.5
-
29
-
-
15444364975
-
Dual functionality of the anti-β1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors
-
Humphries J.D., Schofield N.R., Mostafavi-Pour Z., Green L.G., Garratt A.N., Mould A.P., and Humphries M.J. Dual functionality of the anti-β1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors. J. Biol. Chem. 280 (2005) 10234-10243
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 10234-10243
-
-
Humphries, J.D.1
Schofield, N.R.2
Mostafavi-Pour, Z.3
Green, L.G.4
Garratt, A.N.5
Mould, A.P.6
Humphries, M.J.7
-
30
-
-
0035929622
-
Generation of a minimal α5β1 integrin-Fc fragment
-
Coe A.P.F., Askari J.A., Kline A.D., Robinson M.K., Kirby H., Stephens P.E., and Humphries M.J. Generation of a minimal α5β1 integrin-Fc fragment. J. Biol. Chem. 276 (2001) 35854-35866
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35854-35866
-
-
Coe, A.P.F.1
Askari, J.A.2
Kline, A.D.3
Robinson, M.K.4
Kirby, H.5
Stephens, P.E.6
Humphries, M.J.7
-
31
-
-
20244381778
-
Toll-like receptor-mediated tyrosine phosphorlyation of paxillin via MyD88-dependent and -independent pathways
-
Hazeki K., Masuda N., Funami K., Sukenobu A., Matsumoto M., Akira S., Takeda K., Seya T., and Hazeki O. Toll-like receptor-mediated tyrosine phosphorlyation of paxillin via MyD88-dependent and -independent pathways. Eur. J. Immunol. 33 (2003) 740-747
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 740-747
-
-
Hazeki, K.1
Masuda, N.2
Funami, K.3
Sukenobu, A.4
Matsumoto, M.5
Akira, S.6
Takeda, K.7
Seya, T.8
Hazeki, O.9
-
32
-
-
0037096172
-
Mediators of innate recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
-
Triantafilou M., Miyake K., Golenbock D.T., and Triantafilou K. Mediators of innate recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. J. Cell Sci. 115 (2002) 2603-2611
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2603-2611
-
-
Triantafilou, M.1
Miyake, K.2
Golenbock, D.T.3
Triantafilou, K.4
-
33
-
-
0036500126
-
The involvement of lipid rafts in the regulation of integrin function
-
Leitinger B., and Hogg N. The involvement of lipid rafts in the regulation of integrin function. J. Cell Sci. 115 (2002) 963-972
-
(2002)
J. Cell Sci.
, vol.115
, pp. 963-972
-
-
Leitinger, B.1
Hogg, N.2
-
34
-
-
0025788349
-
CD14 contributes to the adherence of human monocytes to cytokine-stimulated endothelial cells
-
Beekhuizen H., Blokland I., Corsel-van Tilberg A., Koning F., and van Furth R. CD14 contributes to the adherence of human monocytes to cytokine-stimulated endothelial cells. J. Immunol. 147 (1991) 3761-3767
-
(1991)
J. Immunol.
, vol.147
, pp. 3761-3767
-
-
Beekhuizen, H.1
Blokland, I.2
Corsel-van Tilberg, A.3
Koning, F.4
van Furth, R.5
-
35
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
Kobe B., and Kajava A.V. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 11 (2001) 725-732
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
36
-
-
0036721028
-
The small proteoglycan decorin supports adhesion and activation of human platelets
-
Guidetti G., Bertoni A., Viola M., Tira E., Balduini C., and Torti M. The small proteoglycan decorin supports adhesion and activation of human platelets. Blood 100 (2002) 1707-1714
-
(2002)
Blood
, vol.100
, pp. 1707-1714
-
-
Guidetti, G.1
Bertoni, A.2
Viola, M.3
Tira, E.4
Balduini, C.5
Torti, M.6
-
37
-
-
0030052464
-
LPS induces CD14 association with complement receptor type 3, which is reversed by neutrophil adhesion
-
Zarewych D.M., Kindzelskii A.L., Todd R.F., and Petty H.R. LPS induces CD14 association with complement receptor type 3, which is reversed by neutrophil adhesion. J. Immunol. 156 (1996) 430-433
-
(1996)
J. Immunol.
, vol.156
, pp. 430-433
-
-
Zarewych, D.M.1
Kindzelskii, A.L.2
Todd, R.F.3
Petty, H.R.4
-
38
-
-
0037144544
-
Crystal structure of the platelet glycoprotein Ibα N-terminal domain reveals an unmasking mechanism for receptor activation
-
Uff S., Clemetson J.M., Harrison T., Clemetson K.J., and Emsley J. Crystal structure of the platelet glycoprotein Ibα N-terminal domain reveals an unmasking mechanism for receptor activation. J. Biol. Chem. 277 (2002) 35657-35663
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35657-35663
-
-
Uff, S.1
Clemetson, J.M.2
Harrison, T.3
Clemetson, K.J.4
Emsley, J.5
-
39
-
-
0038578608
-
Novel strategies for the treatment of sepsis
-
Riedemann N.C., Guo R.-F., and Ward P.A. Novel strategies for the treatment of sepsis. Nat. Med. 5 (2003) 517-524
-
(2003)
Nat. Med.
, vol.5
, pp. 517-524
-
-
Riedemann, N.C.1
Guo, R.-F.2
Ward, P.A.3
|