-
2
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S., Uematsu S., and Takeuchi O. Pathogen recognition and innate immunity. Cell 124 (2006) 783-801
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
3
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., Takeuchi O., Sugiyama M., Okabe M., Takeda K., and Akira S. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301 (2003) 640-643
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
4
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe K., Du X., Georgel P., Janssen E., Tabeta K., Kim S.O., Goode J., Lin P., Mann N., Mudd S., Crozat K., Sovath S., Han J., and Beutler B. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424 (2003) 743-748
-
(2003)
Nature
, vol.424
, pp. 743-748
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
Crozat, K.11
Sovath, S.12
Han, J.13
Beutler, B.14
-
5
-
-
33748051738
-
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
Honda K., and Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 6 (2006) 644-658
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
6
-
-
0038434274
-
Essential role of IRF-3 in lipopolysaccharide-induced interferon-b gene expression and endotoxin shock
-
Sakaguchi S., Negishi H., Asagiri M., Nakajima C., Mizutani T., Takaoka A., Honda K., and Taniguchi T. Essential role of IRF-3 in lipopolysaccharide-induced interferon-b gene expression and endotoxin shock. Biochem. Biophys. Res. Commun. 306 (2003) 860-866
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.306
, pp. 860-866
-
-
Sakaguchi, S.1
Negishi, H.2
Asagiri, M.3
Nakajima, C.4
Mizutani, T.5
Takaoka, A.6
Honda, K.7
Taniguchi, T.8
-
7
-
-
7444250116
-
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling
-
Honda K., Yanai H., Mizutani T., Negishi H., Shimada N., Suzuki N., Ohba Y., Takaoka A., Yeh W.C., and Taniguchi T. Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling. Proc. Natl. Acad. Sci. USA 101 (2004) 15416-15421
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15416-15421
-
-
Honda, K.1
Yanai, H.2
Mizutani, T.3
Negishi, H.4
Shimada, N.5
Suzuki, N.6
Ohba, Y.7
Takaoka, A.8
Yeh, W.C.9
Taniguchi, T.10
-
8
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., and Taniguchi T. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434 (2005) 772-777
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
Mizutani, T.6
Shimada, N.7
Ohba, Y.8
Takaoka, A.9
Yoshida, N.10
Taniguchi, T.11
-
9
-
-
5444274514
-
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai T., Sato S., Ishii K.J., Coban C., Hemmi H., Yamamoto M., Terai K., Matsuda M., Inoue J., Uematsu S., Takeuchi O., and Akira S. Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat. Immunol. 5 (2004) 1061-1068
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
Coban, C.4
Hemmi, H.5
Yamamoto, M.6
Terai, K.7
Matsuda, M.8
Inoue, J.9
Uematsu, S.10
Takeuchi, O.11
Akira, S.12
-
10
-
-
33750064259
-
Evidence for licensing of IFN-g-induced IRF1 transcription factor by MyD88 in TLR-dependent gene induction program
-
Negishi H., Fujita Y., Yanai H., Sakaguchi S., Ouyang X., Shinohara M., Takayanagi H., Ohba Y., Taniguchi T., and Honda K. Evidence for licensing of IFN-g-induced IRF1 transcription factor by MyD88 in TLR-dependent gene induction program. Proc. Natl. Acad. Sci. USA 103 (2006) 15136-15141
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15136-15141
-
-
Negishi, H.1
Fujita, Y.2
Yanai, H.3
Sakaguchi, S.4
Ouyang, X.5
Shinohara, M.6
Takayanagi, H.7
Ohba, Y.8
Taniguchi, T.9
Honda, K.10
-
11
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.W., and Taniguchi T. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434 (2005) 243-249
-
(2005)
Nature
, vol.434
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
Mizutani, T.6
Kano, S.7
Honda, K.8
Ohba, Y.9
Mak, T.W.10
Taniguchi, T.11
-
12
-
-
0034671772
-
Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways
-
Sato S., Nomura F., Kawai T., Takeuchi O., Muhlradt P.F., Takeda K., and Akira S. Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways. J. Immunol. 165 (2000) 7096-7101
-
(2000)
J. Immunol.
, vol.165
, pp. 7096-7101
-
-
Sato, S.1
Nomura, F.2
Kawai, T.3
Takeuchi, O.4
Muhlradt, P.F.5
Takeda, K.6
Akira, S.7
-
13
-
-
4143131229
-
Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity
-
Whitmore M.M., DeVeer M.J., Edling A., Oates R.K., Simons B., Lindner D., and Williams B.R. Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res. 64 (2004) 5850-5860
-
(2004)
Cancer Res.
, vol.64
, pp. 5850-5860
-
-
Whitmore, M.M.1
DeVeer, M.J.2
Edling, A.3
Oates, R.K.4
Simons, B.5
Lindner, D.6
Williams, B.R.7
-
14
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani G., Rinaldi A., Bertoni F., Sallusto F., and Lanzavecchia A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6 (2005) 769-776
-
(2005)
Nat. Immunol.
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
15
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
-
Sato M., Suemori H., Hata N., Asagiri M., Ogasawara K., Nakao K., Nakaya T., Katsuki M., Noguchi S., Tanaka N., and Taniguchi T. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13 (2000) 539-548
-
(2000)
Immunity
, vol.13
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
Asagiri, M.4
Ogasawara, K.5
Nakao, K.6
Nakaya, T.7
Katsuki, M.8
Noguchi, S.9
Tanaka, N.10
Taniguchi, T.11
-
16
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg A.M., Yi A.K., Matson S., Waldschmidt T.J., Bishop G.A., Teasdale R., Koretzky G.A., and Klinman D.M. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374 (1995) 546-549
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
17
-
-
0031897632
-
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
-
Ghosh S., May M.J., and Kopp E.B. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16 (1998) 225-260
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
18
-
-
27644548945
-
Negative regulation of Toll-like-receptor signaling by IRF-4
-
Negishi H., Ohba Y., Yanai H., Takaoka A., Honma K., Yui K., Matsuyama T., Taniguchi T., and Honda K. Negative regulation of Toll-like-receptor signaling by IRF-4. Proc. Natl. Acad. Sci. USA 102 (2005) 15989-15994
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15989-15994
-
-
Negishi, H.1
Ohba, Y.2
Yanai, H.3
Takaoka, A.4
Honma, K.5
Yui, K.6
Matsuyama, T.7
Taniguchi, T.8
Honda, K.9
|