-
1
-
-
0036490096
-
Regulators of G-protein signalling as new central nervous system drug targets
-
Neubig R.R., and Siderovski D.R. Regulators of G-protein signalling as new central nervous system drug targets. Nat. Rev. Drug Discovery 1 (2002) 187-197
-
(2002)
Nat. Rev. Drug Discovery
, vol.1
, pp. 187-197
-
-
Neubig, R.R.1
Siderovski, D.R.2
-
2
-
-
0031041306
-
RGS proteins and signaling by heterotrimeric G proteins
-
Dohlman H.G., and Thorner J. RGS proteins and signaling by heterotrimeric G proteins. J. Biol. Chem. 272 (1997) 3871-3874
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3871-3874
-
-
Dohlman, H.G.1
Thorner, J.2
-
3
-
-
0033199157
-
Emerging roles for RGS proteins in cell signalling
-
Hepler J.R. Emerging roles for RGS proteins in cell signalling. Trends Pharmacol. Sci. 20 (1999) 376-382
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 376-382
-
-
Hepler, J.R.1
-
4
-
-
17344367802
-
2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
-
2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors. Nat. Cell. Biol. 7 (2005) 405-411
-
(2005)
Nat. Cell. Biol.
, vol.7
, pp. 405-411
-
-
Wang, X.1
-
5
-
-
14044273637
-
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family
-
Martemyanov K.A., Yoo P.J., Skiba N.P., and Arshavsky V.Y. R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family. J. Biol. Chem. 280 (2005) 5133-5136
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5133-5136
-
-
Martemyanov, K.A.1
Yoo, P.J.2
Skiba, N.P.3
Arshavsky, V.Y.4
-
6
-
-
2442717874
-
RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling
-
Bernstein L.S., Ramineni S., Hague C., Cladman W., Chidiac P., Levey A.I., and Hepler J.R. RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling. J. Biol. Chem. 279 (2004) 21248-21256
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21248-21256
-
-
Bernstein, L.S.1
Ramineni, S.2
Hague, C.3
Cladman, W.4
Chidiac, P.5
Levey, A.I.6
Hepler, J.R.7
-
7
-
-
0037162461
-
R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1
-
Hu G., and Wensel T.G. R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. Proc. Natl. Acad. Sci. USA 99 (2002) 9755-9760
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9755-9760
-
-
Hu, G.1
Wensel, T.G.2
-
8
-
-
33748590520
-
DEP-domain-mediated regulation of GPCR signaling responses
-
Ballon D.R., Flanary P.L., Gladue D.P., Konopka J.B., Dohlman H.G., and Thorner J. DEP-domain-mediated regulation of GPCR signaling responses. Cell 126 (2006) 1079-1093
-
(2006)
Cell
, vol.126
, pp. 1079-1093
-
-
Ballon, D.R.1
Flanary, P.L.2
Gladue, D.P.3
Konopka, J.B.4
Dohlman, H.G.5
Thorner, J.6
-
9
-
-
0032514630
-
GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP
-
De Vries L., Lou X., Zhao G., Zheng B., and Farquhar M.G. GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP. Proc. Natl. Acad. Sci. USA 95 (1998) 12340-12345
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12340-12345
-
-
De Vries, L.1
Lou, X.2
Zhao, G.3
Zheng, B.4
Farquhar, M.G.5
-
10
-
-
0030611942
-
Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits
-
Tu Y., Wang J., and Ross E.M. Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits. Science 278 (1997) 1132-1135
-
(1997)
Science
, vol.278
, pp. 1132-1135
-
-
Tu, Y.1
Wang, J.2
Ross, E.M.3
-
11
-
-
0030448762
-
GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits
-
De Vries L., Elenko E., Hubler L., Jones T.L., and Farquhar M.G. GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits. Proc. Natl. Acad. Sci. USA 93 (1996) 15203-15208
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15203-15208
-
-
De Vries, L.1
Elenko, E.2
Hubler, L.3
Jones, T.L.4
Farquhar, M.G.5
-
13
-
-
0040142258
-
The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5
-
Chen C., Seow K.T., Guo K., Yaw L.P., and Lin S.C. The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5. J. Biol. Chem. 274 (1999) 19799-19806
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19799-19806
-
-
Chen, C.1
Seow, K.T.2
Guo, K.3
Yaw, L.P.4
Lin, S.C.5
-
15
-
-
0035957996
-
Mechanisms governing subcellular localization and function of human RGS2
-
Heximer S.P., Lim H., Bernard J.L., and Blumer K.J. Mechanisms governing subcellular localization and function of human RGS2. J. Biol. Chem. 276 (2001) 14195-14203
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14195-14203
-
-
Heximer, S.P.1
Lim, H.2
Bernard, J.L.3
Blumer, K.J.4
-
16
-
-
0035895877
-
Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K+ channels
-
Saitoh O., Masuho I., Terakawa I., Nomoto S., Asano T., and Kubo Y. Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K+ channels. J. Biol. Chem. 276 (2001) 5052-5058
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5052-5058
-
-
Saitoh, O.1
Masuho, I.2
Terakawa, I.3
Nomoto, S.4
Asano, T.5
Kubo, Y.6
-
17
-
-
0036733358
-
Cellular regulation of RGS proteins: modulators and integrators of G protein signaling
-
Hollinger S., and Hepler J.R. Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol. Rev. 54 (2002) 527-559
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 527-559
-
-
Hollinger, S.1
Hepler, J.R.2
-
18
-
-
0038446043
-
Activity, regulation, and intracellular localization of RGS proteins
-
Chidiac P., and Roy A.A. Activity, regulation, and intracellular localization of RGS proteins. Receptors Channels 9 (2003) 135-147
-
(2003)
Receptors Channels
, vol.9
, pp. 135-147
-
-
Chidiac, P.1
Roy, A.A.2
-
19
-
-
0035827527
-
Binding of regulator of G protein signaling (RGS) proteins to phospholipid bilayers. Contribution of location and/or orientation to Gtpase-activating protein activity
-
Tu Y., Woodson J., and Ross E.M. Binding of regulator of G protein signaling (RGS) proteins to phospholipid bilayers. Contribution of location and/or orientation to Gtpase-activating protein activity. J. Biol. Chem. 276 (2001) 20160-20166
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20160-20166
-
-
Tu, Y.1
Woodson, J.2
Ross, E.M.3
-
20
-
-
0038514242
-
Regulators of G-protein signaling (RGS) 4, insertion into model membranes and inhibition of activity by phosphatidic acid
-
Ouyang Y.S., Tu Y., Barker S.A., and Yang F. Regulators of G-protein signaling (RGS) 4, insertion into model membranes and inhibition of activity by phosphatidic acid. J. Biol. Chem. 278 (2003) 11115-11122
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11115-11122
-
-
Ouyang, Y.S.1
Tu, Y.2
Barker, S.A.3
Yang, F.4
-
21
-
-
17144381258
-
Regulators of G-protein signalling form a quaternary complex with the agonist, receptor and G-protein: a novel explanation for the acceleration of signalling activation kinetics
-
Benians A., Nobles M., Hosny S., and Tinker A. Regulators of G-protein signalling form a quaternary complex with the agonist, receptor and G-protein: a novel explanation for the acceleration of signalling activation kinetics. J. Biol. Chem. 280 (2005) 13383-13394
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 13383-13394
-
-
Benians, A.1
Nobles, M.2
Hosny, S.3
Tinker, A.4
-
22
-
-
12244309566
-
Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation
-
Zhang Q., Pacheco M.A., and Doupnik C.A. Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation. J. Physiol. 545 (2002) 355-373
-
(2002)
J. Physiol.
, vol.545
, pp. 355-373
-
-
Zhang, Q.1
Pacheco, M.A.2
Doupnik, C.A.3
-
23
-
-
27844531564
-
RGS2 interacts with Gs and adenylyl cyclase in living cells
-
Roy A.A., Baragli A., Bernstein L.S., Hepler J.R., Hebert T.E., and Chidiac P. RGS2 interacts with Gs and adenylyl cyclase in living cells. Cell Signal. 18 (2006) 336-348
-
(2006)
Cell Signal.
, vol.18
, pp. 336-348
-
-
Roy, A.A.1
Baragli, A.2
Bernstein, L.S.3
Hepler, J.R.4
Hebert, T.E.5
Chidiac, P.6
-
25
-
-
33645098367
-
Endogenous regulator of G-protein signaling proteins regulate the kinetics of Galphaq/11-mediated modulation of ion channels in central nervous system neurons
-
Clark M.A., and Lambert N.A. Endogenous regulator of G-protein signaling proteins regulate the kinetics of Galphaq/11-mediated modulation of ion channels in central nervous system neurons. Mol. Pharmacol. 69 (2006) 1280-1287
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1280-1287
-
-
Clark, M.A.1
Lambert, N.A.2
-
26
-
-
0041854353
-
Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions
-
Roy A.A., Lemberg K.E., and Chidiac P. Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions. Mol. Pharmacol. 64 (2003) 587-593
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 587-593
-
-
Roy, A.A.1
Lemberg, K.E.2
Chidiac, P.3
-
27
-
-
17344374133
-
Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity
-
Ingi T., et al. Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity. J. Neurosci. 18 (1998) 7178-7188
-
(1998)
J. Neurosci.
, vol.18
, pp. 7178-7188
-
-
Ingi, T.1
-
28
-
-
0027245830
-
Substitution of 3 amino-acids switches receptor specificity of G(Q)alpha to that of G(I)alpha
-
Conklin B.R., Farfel Z., Lustig K.D., Julius D., and Bourne H.R. Substitution of 3 amino-acids switches receptor specificity of G(Q)alpha to that of G(I)alpha. Nature 363 (1993) 274-276
-
(1993)
Nature
, vol.363
, pp. 274-276
-
-
Conklin, B.R.1
Farfel, Z.2
Lustig, K.D.3
Julius, D.4
Bourne, H.R.5
-
29
-
-
2942655668
-
Dynamics of putative raft-associated proteins at the cell surface
-
Kenworthy A.K., Nichols B.J., Remmert C.L., Hendrix G.M., Kumar M., Zimmerberg J., and Lippincott-Schwartz J. Dynamics of putative raft-associated proteins at the cell surface. J. Cell. Biol. 165 (2004) 735-746
-
(2004)
J. Cell. Biol.
, vol.165
, pp. 735-746
-
-
Kenworthy, A.K.1
Nichols, B.J.2
Remmert, C.L.3
Hendrix, G.M.4
Kumar, M.5
Zimmerberg, J.6
Lippincott-Schwartz, J.7
-
30
-
-
15644373915
-
GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain
-
Snow B.E., et al. GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain. J. Biol. Chem. 273 (1998) 17749-17755
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17749-17755
-
-
Snow, B.E.1
-
31
-
-
0031474423
-
RGS2/G0S8 is a selective inhibitor of Gqalpha function
-
Heximer S.P., Watson N., Linder M.E., Blumer K.J., and Hepler J.R. RGS2/G0S8 is a selective inhibitor of Gqalpha function. Proc. Natl. Acad. Sci. USA 94 (1997) 14389-14393
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14389-14393
-
-
Heximer, S.P.1
Watson, N.2
Linder, M.E.3
Blumer, K.J.4
Hepler, J.R.5
-
33
-
-
0034467579
-
Regulators of G-protein signaling in receptor complexes
-
Sierra D.A., Popov S., and Wilkie T.M. Regulators of G-protein signaling in receptor complexes. Trends Cardiovasc. Med. 10 (2000) 263-268
-
(2000)
Trends Cardiovasc. Med.
, vol.10
, pp. 263-268
-
-
Sierra, D.A.1
Popov, S.2
Wilkie, T.M.3
-
34
-
-
30944451158
-
RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins
-
Abramow-Newerly M., Roy A.A., Nunn C., and Chidiac P. RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins. Cell Signal. 18 (2006) 579-591
-
(2006)
Cell Signal.
, vol.18
, pp. 579-591
-
-
Abramow-Newerly, M.1
Roy, A.A.2
Nunn, C.3
Chidiac, P.4
-
35
-
-
10644231812
-
Participation of RGS8 in the ternary complex of agonist, receptor and G-protein
-
Benians A., Nobles M., and Tinker A. Participation of RGS8 in the ternary complex of agonist, receptor and G-protein. Biochem. Soc. Trans. 32 (2004) 1045-1047
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 1045-1047
-
-
Benians, A.1
Nobles, M.2
Tinker, A.3
-
36
-
-
33845942736
-
RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation: Precoupling and Collision coupling
-
Jaen C., and Doupnik C.A. RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation: Precoupling and Collision coupling. J. Biol. Chem. 281 (2006) 34549-34560
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 34549-34560
-
-
Jaen, C.1
Doupnik, C.A.2
-
37
-
-
17644385537
-
Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells
-
Mutneja M., Berton F., Suen K.F., Luscher C., and Slesinger P.A. Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells. Pflugers Arch. 450 (2005) 61-73
-
(2005)
Pflugers Arch.
, vol.450
, pp. 61-73
-
-
Mutneja, M.1
Berton, F.2
Suen, K.F.3
Luscher, C.4
Slesinger, P.A.5
-
38
-
-
0032567439
-
The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling
-
Zeng W.Z., et al. The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling. J. Biol. Chem. 273 (1998) 34687-34690
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34687-34690
-
-
Zeng, W.Z.1
|