Chimeric DNA-RNA hammerhead ribozyme targeting transforming growth factor-β1 mRNA ameliorates renal injury in hypertensive rats

Journal of Hypertension

Volumn 25, Issue 3, 2007, Pages 671-678

  Tahira, Yoshiko ^a   Fukuda, Noboru ^a,b   Endo, Morito ^c   Ueno, Takahiro ^a   Matsuda, Hiroyuki ^a   Saito, Satoshi ^a   Matsumoto, Koichi ^a   Mugishima, Hideo ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c Hachinohe University   (Japan)

Author keywords

Gene therapy; Glomerulosclerosis; Hypertension; Ribozyme; Transforming growth factor 1

Indexed keywords

CHIMERIC PROTEIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; DNA; FIBRONECTIN; HAMMERHEAD RIBOZYME; MESSENGER RNA; POLYETHYLENEIMINE; RNA; SCLEROPROTEIN; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; BLOOD PRESSURE; CAPILLARY; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; DNA RNA HYBRIDIZATION; DOWN REGULATION; DRUG DESIGN; DRUG EFFECT; GENETIC TRANSFECTION; GLOMERULOSCLEROSIS; GLOMERULUS; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CORTEX; KIDNEY INJURY; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RAT; RIBOZYME THERAPY; SPONTANEOUSLY HYPERTENSIVE HEART FAILURE RAT;

EID: 33846781413     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e3280122f22     Document Type: Article

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