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Volumn 9, Issue 1, 1998, Pages 1-10

Therapeutic ribozymes: Principles and applications

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; RIBOZYME;

EID: 0031963232     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: 10.2165/00063030-199809010-00001     Document Type: Review
Times cited : (14)

References (56)
  • 1
    • 0020417286 scopus 로고
    • Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena
    • Kruger K, Grabowski PJ, Zaug AJ, et al. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell 1982; 31: 147-57
    • (1982) Cell , vol.31 , pp. 147-157
    • Kruger, K.1    Grabowski, P.J.2    Zaug, A.J.3
  • 2
    • 0021013526 scopus 로고
    • The RNA moiety of ribonuclease P is the catalylic subunit of the enzyme
    • Guerrier-Takada C, Gardiner K, Marsh T, et al. The RNA moiety of ribonuclease P is the catalylic subunit of the enzyme. Cell 1983; 35: 849-57
    • (1983) Cell , vol.35 , pp. 849-857
    • Guerrier-Takada, C.1    Gardiner, K.2    Marsh, T.3
  • 3
  • 4
    • 0028428909 scopus 로고
    • Making ribozymes work in cells
    • Rossi JJ. Making ribozymes work in cells. Curr Biol 1994; 4: 469-71
    • (1994) Curr Biol , vol.4 , pp. 469-471
    • Rossi, J.J.1
  • 5
    • 0027987902 scopus 로고
    • Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing
    • Sullenger BA, Cech TR. Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. Nature 1992; 371: 619-22
    • (1992) Nature , vol.371 , pp. 619-622
    • Sullenger, B.A.1    Cech, T.R.2
  • 6
    • 85190569045 scopus 로고
    • Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity
    • Young B, Herschlag D, Cech TR. Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity. Cell 1991; 29: 10159-71
    • (1991) Cell , vol.29 , pp. 10159-10171
    • Young, B.1    Herschlag, D.2    Cech, T.R.3
  • 7
    • 0027732494 scopus 로고
    • Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism
    • Dahm SC, Derrick WB, Uhlenbeck OC. Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. Biochemistry 1993; 32: 13040-5
    • (1993) Biochemistry , vol.32 , pp. 13040-13045
    • Dahm, S.C.1    Derrick, W.B.2    Uhlenbeck, O.C.3
  • 8
    • 0025695458 scopus 로고
    • Sequence requirements of the hammerhead RNA self-cleavage reaction
    • Ruffner DE, Stormo GD, Uhlenbeck OC. Sequence requirements of the hammerhead RNA self-cleavage reaction. Biochemistry 1990; 29: 10695-702
    • (1990) Biochemistry , vol.29 , pp. 10695-10702
    • Ruffner, D.E.1    Stormo, G.D.2    Uhlenbeck, O.C.3
  • 9
    • 0025968051 scopus 로고
    • Ribozymes that cleave an RNA sequence from human immunodeficiency virus: The effect of flanking sequence on rate
    • Goodchild J, Kohli V. Ribozymes that cleave an RNA sequence from human immunodeficiency virus: the effect of flanking sequence on rate. Arch Biochem Biophys 1991; 284: 386-91
    • (1991) Arch Biochem Biophys , vol.284 , pp. 386-391
    • Goodchild, J.1    Kohli, V.2
  • 10
    • 0026439909 scopus 로고
    • A ribozyme with DNA in the hybridising arms displays enhanced cleavage ability
    • Hendry P, McCall MJ, Santiago FS, et al. A ribozyme with DNA in the hybridising arms displays enhanced cleavage ability. Nucleic Acids Res 1992; 20: 5737-41
    • (1992) Nucleic Acids Res , vol.20 , pp. 5737-5741
    • Hendry, P.1    McCall, M.J.2    Santiago, F.S.3
  • 11
    • 0026529507 scopus 로고
    • Nuclease resistant ribozymes with high catalytic activity
    • Paolella G, Sproat BS, Lamond AI. Nuclease resistant ribozymes with high catalytic activity. EMBO J 1992; 11: 1913-9
    • (1992) EMBO J , vol.11 , pp. 1913-1919
    • Paolella, G.1    Sproat, B.S.2    Lamond, A.I.3
  • 12
    • 0026672823 scopus 로고
    • Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo
    • Taylor NR, Kaplan BE, Swiderski P, et al. Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo. Nucleic Acids Res 1992; 20: 4559-65
    • (1992) Nucleic Acids Res , vol.20 , pp. 4559-4565
    • Taylor, N.R.1    Kaplan, B.E.2    Swiderski, P.3
  • 14
    • 0027955448 scopus 로고
    • High activity and stability of hammerhead ribozymes containing 2′-modified pyrimidine nucleosides and phosphorothioates
    • Heidenreich O, Benseler P, Fahrenholz A, et al. High activity and stability of hammerhead ribozymes containing 2′-modified pyrimidine nucleosides and phosphorothioates. J Biol Chem 1994; 269: 2131-8
    • (1994) J Biol Chem , vol.269 , pp. 2131-2138
    • Heidenreich, O.1    Benseler, P.2    Fahrenholz, A.3
  • 15
    • 10544234615 scopus 로고    scopus 로고
    • Optimizing the cell efficacy of synthetic ribozymes: Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb
    • Jarvis TC, Wincott FE, Laverna JA, et al. Optimizing the cell efficacy of synthetic ribozymes: site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb. J Biol Chem 1996; 271: 29107-12
    • (1996) J Biol Chem , vol.271 , pp. 29107-29112
    • Jarvis, T.C.1    Wincott, F.E.2    Laverna, J.A.3
  • 16
    • 0028288686 scopus 로고
    • A kinetic and thermodynamic framework for the hammerhead ribozyme reaction
    • Hertel KJ, Herschlag D, Uhlenbeck OC. A kinetic and thermodynamic framework for the hammerhead ribozyme reaction. Biochemistry 1994; 33: 3374-85
    • (1994) Biochemistry , vol.33 , pp. 3374-3385
    • Hertel, K.J.1    Herschlag, D.2    Uhlenbeck, O.C.3
  • 17
    • 0028906353 scopus 로고
    • The internal equilibrium of the hammerhead ribozyme reaction
    • Hertel KJ, Uhlenbeck OC. The internal equilibrium of the hammerhead ribozyme reaction. Biochemistry 1995; 34: 1744-9
    • (1995) Biochemistry , vol.34 , pp. 1744-1749
    • Hertel, K.J.1    Uhlenbeck, O.C.2
  • 18
    • 0026515136 scopus 로고
    • Functional characterization of a U5 ribozyme: Intracellular suppression of human immunodeficiency virus type 1 expression
    • Dropulic B, Lin NH, Martin MA, et al. Functional characterization of a U5 ribozyme: intracellular suppression of human immunodeficiency virus type 1 expression. J Virol 1992; 66: 1432-41
    • (1992) J Virol , vol.66 , pp. 1432-1441
    • Dropulic, B.1    Lin, N.H.2    Martin, M.A.3
  • 19
    • 6844248803 scopus 로고
    • A virus model for examining the intracellular efficiency of a ribozyme targeted to HIV-1
    • Dropulic B, Jeang KT. A virus model for examining the intracellular efficiency of a ribozyme targeted to HIV-1. Methods: a Companion to Methods in Enzymology 1993; 5: 43-9
    • (1993) Methods: A Companion to Methods in Enzymology , vol.5 , pp. 43-49
    • Dropulic, B.1    Jeang, K.T.2
  • 20
    • 0027516209 scopus 로고
    • An anti-lymphocytic choriomeningitis virus ribozyme expressed in tissue culture cells diminishes viral RNA levels and leads to a reduction in infectious virus yield
    • Xing Z, Whitton JL. An anti-lymphocytic choriomeningitis virus ribozyme expressed in tissue culture cells diminishes viral RNA levels and leads to a reduction in infectious virus yield. J Virol 1993; 67: 1840-7
    • (1993) J Virol , vol.67 , pp. 1840-1847
    • Xing, Z.1    Whitton, J.L.2
  • 21
    • 0028275081 scopus 로고
    • Can hammerhead ribozymes be efficient tools to inactivate gene function?
    • published erratum appears in Nucleic Acids Res 1994 Apr 11; 22 (7): 1326
    • Bertrand E, Pictet R, Frange T. Can hammerhead ribozymes be efficient tools to inactivate gene function? [published erratum appears in Nucleic Acids Res 1994 Apr 11; 22 (7): 1326]. Nucleic Acids Res 1994; 22: 293-300
    • (1994) Nucleic Acids Res , vol.22 , pp. 293-300
    • Bertrand, E.1    Pictet, R.2    Frange, T.3
  • 22
    • 0027742736 scopus 로고
    • Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA
    • Sullenger B, Cech TR. Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. Science 1993; 262: 1566-9
    • (1993) Science , vol.262 , pp. 1566-1569
    • Sullenger, B.1    Cech, T.R.2
  • 23
    • 0024357988 scopus 로고
    • Specific gene suppression by engineered ribozymes in monkey cells
    • Cameron FH, Jennings PA. Specific gene suppression by engineered ribozymes in monkey cells. Proc Natl Acad Sci USA 1989; 86: 9139-43
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9139-9143
    • Cameron, F.H.1    Jennings, P.A.2
  • 24
    • 0026562551 scopus 로고
    • Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo
    • Steinecke P, Herget T, Schreier PH. Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo. EMBO J 1992; 11: 1525-30
    • (1992) EMBO J , vol.11 , pp. 1525-1530
    • Steinecke, P.1    Herget, T.2    Schreier, P.H.3
  • 25
    • 0027375250 scopus 로고
    • Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila
    • Zhao JJ, Pick L. Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila. Nature 1993; 365: 448-51
    • (1993) Nature , vol.365 , pp. 448-451
    • Zhao, J.J.1    Pick, L.2
  • 26
    • 0028295284 scopus 로고
    • Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion
    • Efrat S, Fusco-DeMane M, Wu Y-J, et al. Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion. Proc Natl Acad Sci USA 1994; 91: 2051-5
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2051-2055
    • Efrat, S.1    Fusco-DeMane, M.2    Wu, Y.-J.3
  • 27
    • 0028177915 scopus 로고
    • Reduced β2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme
    • Larsson S, Hotchkiss G, Andang M, et al. Reduced β2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme. Nucleic Acids Res 1994; 22: 2242-8
    • (1994) Nucleic Acids Res , vol.22 , pp. 2242-2248
    • Larsson, S.1    Hotchkiss, G.2    Andang, M.3
  • 28
    • 0025363891 scopus 로고
    • Ribozymes as potential anti-HIV-1 therapeutic agents
    • Sarver N, Cantin EM, Chang PS, et al. Ribozymes as potential anti-HIV-1 therapeutic agents. Science 1990; 247: 1222-5
    • (1990) Science , vol.247 , pp. 1222-1225
    • Sarver, N.1    Cantin, E.M.2    Chang, P.S.3
  • 29
    • 0027973382 scopus 로고
    • Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes
    • Zhou C, Bahner IC, Larson GP, et al. Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes. Gene 1994; 149: 33-9
    • (1994) Gene , vol.149 , pp. 33-39
    • Zhou, C.1    Bahner, I.C.2    Larson, G.P.3
  • 30
    • 0030935630 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34+ cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes
    • Bauer G, Valdez P, Kearns K, et al. Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34+ cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes. Blood 1997; 89 (7): 2259-67
    • (1997) Blood , vol.89 , Issue.7 , pp. 2259-2267
    • Bauer, G.1    Valdez, P.2    Kearns, K.3
  • 31
    • 0026779558 scopus 로고
    • Multitargetribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication: Potential effectiveness against most presently sequenced HIV-1 isolates
    • Chen CJ, Banerjea AC, Harmison GG, et al. Multitargetribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication: potential effectiveness against most presently sequenced HIV-1 isolates. Nucleic Acids Res 1992; 20: 4581-9
    • (1992) Nucleic Acids Res , vol.20 , pp. 4581-4589
    • Chen, C.J.1    Banerjea, A.C.2    Harmison, G.G.3
  • 32
    • 0027445682 scopus 로고
    • Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro
    • Crisell P, Thompson S, James W. Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro. Nucleic Acids Res 1993; 21: 5251-5
    • (1993) Nucleic Acids Res , vol.21 , pp. 5251-5255
    • Crisell, P.1    Thompson, S.2    James, W.3
  • 33
    • 0029764099 scopus 로고    scopus 로고
    • A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread
    • Dropulic B, Hermankova M, Pitha PM. A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread. Proc Natl Acad Sci USA 1996; 93: 11103-8
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11103-11108
    • Dropulic, B.1    Hermankova, M.2    Pitha, P.M.3
  • 34
    • 0026785305 scopus 로고
    • Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA
    • Lo KM, Biasolo MA, Dehni G, et al. Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA. Virology 1992; 190: 176-83
    • (1992) Virology , vol.190 , pp. 176-183
    • Lo, K.M.1    Biasolo, M.A.2    Dehni, G.3
  • 35
    • 0026496702 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme
    • Ojwang JO, Hampel A, Looney DJ, et al. Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme. Proc Natl Acad Sci USA 1992; 89: 10802-6
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10802-10806
    • Ojwang, J.O.1    Hampel, A.2    Looney, D.J.3
  • 36
    • 0026055747 scopus 로고
    • Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme
    • Weerasinghe M, Liem SR, Asad S, et al. Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme. J Virol 1991; 65: 5531-4
    • (1991) J Virol , vol.65 , pp. 5531-5534
    • Weerasinghe, M.1    Liem, S.R.2    Asad, S.3
  • 37
    • 0028051280 scopus 로고
    • Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1
    • Yamada O, Yu M, Yee JK, et al. Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1. Gene Ther 1994; 1: 38-45
    • (1994) Gene Ther , vol.1 , pp. 38-45
    • Yamada, O.1    Yu, M.2    Yee, J.K.3
  • 38
    • 0027264877 scopus 로고
    • A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1
    • published erratum appears in Proc Natl Acad Sci USA 1993 Sep 1: 90 (17): 8303
    • Yu M, Ojwang J, Yamada O, et al. A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1 [published erratum appears in Proc Natl Acad Sci USA 1993 Sep 1: 90 (17): 8303]. Proc Natl Acad Sci USA 1993; 90: 6340-4
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6340-6344
    • Yu, M.1    Ojwang, J.2    Yamada, O.3
  • 39
    • 0025342694 scopus 로고
    • HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
    • Zack JA, Arrigo SJ, Weitsman SR, et al. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell 1990; 61: 213-22
    • (1990) Cell , vol.61 , pp. 213-222
    • Zack, J.A.1    Arrigo, S.J.2    Weitsman, S.R.3
  • 40
    • 0029970824 scopus 로고    scopus 로고
    • Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes
    • Lieber A, He CY, Polyak SJ, et al. Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes. J Virol 1996; 70: 8782-91
    • (1996) J Virol , vol.70 , pp. 8782-8791
    • Lieber, A.1    He, C.Y.2    Polyak, S.J.3
  • 41
    • 0026653293 scopus 로고
    • Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Haras gene
    • Koizumi M, Kamiya H, Ohtsuka E. Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Haras gene. Gene 1992; 117: 179-84
    • (1992) Gene , vol.117 , pp. 179-184
    • Koizumi, M.1    Kamiya, H.2    Ohtsuka, E.3
  • 42
    • 0030179370 scopus 로고    scopus 로고
    • Tumor inhibitory activity of anti-ras ribozymes delivered by retroviral gene transfer
    • Li M, Lonial H, Citarella R, et al. Tumor inhibitory activity of anti-ras ribozymes delivered by retroviral gene transfer. Cancer Gene Ther 1996; 3: 221-9
    • (1996) Cancer Gene Ther , vol.3 , pp. 221-229
    • Li, M.1    Lonial, H.2    Citarella, R.3
  • 43
    • 0027218359 scopus 로고
    • Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line
    • Snyder DS, Wu Y, Wang JL, et al. Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line. Blood 1993; 82: 600-5
    • (1993) Blood , vol.82 , pp. 600-605
    • Snyder, D.S.1    Wu, Y.2    Wang, J.L.3
  • 44
    • 0027384743 scopus 로고
    • Ribozyme-mediated cleavage of the BCR-ABL oncogene transcript: In vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity
    • Shore SK, Nabissa PM, Reddy EP. Ribozyme-mediated cleavage of the BCR-ABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity. Oncogene 1993; 8: 3183-8
    • (1993) Oncogene , vol.8 , pp. 3183-3188
    • Shore, S.K.1    Nabissa, P.M.2    Reddy, E.P.3
  • 45
    • 0029829944 scopus 로고    scopus 로고
    • mdr1 ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines
    • Daly C, Coyle S, McBride S, et al. mdr1 ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines. Cytotechnology 1996; 19: 199-205
    • (1996) Cytotechnology , vol.19 , pp. 199-205
    • Daly, C.1    Coyle, S.2    McBride, S.3
  • 46
    • 0029855988 scopus 로고    scopus 로고
    • Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin
    • Czubayko F, Schulte AM, Berchem GJ, et al. Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin. Proc Natl Acad Sci USA 1996; 93: 14753-8
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14753-14758
    • Czubayko, F.1    Schulte, A.M.2    Berchem, G.J.3
  • 47
    • 0030583250 scopus 로고    scopus 로고
    • Hammerhead ribozyme-mediated inhibition of telomerase activity in extracts of human hepatocellular carcinoma cells
    • Kanazawa Y, Ohkawa K, Ueda K, et al. Hammerhead ribozyme-mediated inhibition of telomerase activity in extracts of human hepatocellular carcinoma cells. Biochem Biophys Res Commun 1996; 225: 570-6
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 570-576
    • Kanazawa, Y.1    Ohkawa, K.2    Ueda, K.3
  • 48
    • 0029804836 scopus 로고
    • Delivery of a hammerhead ribozyme specifically down-regulates the production of fibrillin-1 by cultured dermal fibroblasts
    • Kilpatrick MW, Phylactou LA, Godfrey M, et al. Delivery of a hammerhead ribozyme specifically down-regulates the production of fibrillin-1 by cultured dermal fibroblasts. Hum Mol Genet 1966; 5: 1939-44
    • (1966) Hum Mol Genet , vol.5 , pp. 1939-1944
    • Kilpatrick, M.W.1    Phylactou, L.A.2    Godfrey, M.3
  • 49
    • 0029938672 scopus 로고    scopus 로고
    • Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by peritoneal cells in vitro and in vivo
    • Sioud M. Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by peritoneal cells in vitro and in vivo. Eur J Immunol 1996; 26: 1026-31
    • (1996) Eur J Immunol , vol.26 , pp. 1026-1031
    • Sioud, M.1
  • 50
    • 15844379355 scopus 로고    scopus 로고
    • Matrix metalloproteinex 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation
    • Turck J, Pollock AS, Lee LK, et al. Matrix metalloproteinex 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation. J Biol Chem 1996; 271: 15074-83
    • (1996) J Biol Chem , vol.271 , pp. 15074-15083
    • Turck, J.1    Pollock, A.S.2    Lee, L.K.3
  • 51
    • 0029959522 scopus 로고    scopus 로고
    • Inhibition of vascular smooth muscle cell proliferation by ribozymes that cleave c-myb mRNA
    • Jarvis TC, Alby LJ, Beaudry AA, et al. Inhibition of vascular smooth muscle cell proliferation by ribozymes that cleave c-myb mRNA. RNA 1996; 2: 419-28
    • (1996) RNA , vol.2 , pp. 419-428
    • Jarvis, T.C.1    Alby, L.J.2    Beaudry, A.A.3
  • 54
    • 0028355964 scopus 로고
    • Facilitation of hammerhead ribozyme catalysis by the nucleocapsid protein of HIV-1 and the heterogeneous nuclear ribonucleoprotein AI
    • Bertrand EL, Rossi JJ. Facilitation of hammerhead ribozyme catalysis by the nucleocapsid protein of HIV-1 and the heterogeneous nuclear ribonucleoprotein AI. EMBO J 1994; 13: 2904-12
    • (1994) EMBO J , vol.13 , pp. 2904-2912
    • Bertrand, E.L.1    Rossi, J.J.2
  • 55
    • 0028216716 scopus 로고
    • An RNA chaperone activity of non-specific RNA binding proteins in hammerhead ribozyme catalysis
    • published erratum appears in EMBO J 1994 Aug 15; 13(16): 3926
    • Herschlag D, Khosla M, Tsuchihashi Z, et al. An RNA chaperone activity of non-specific RNA binding proteins in hammerhead ribozyme catalysis [published erratum appears in EMBO J 1994 Aug 15; 13(16): 3926]. EMBO J 1994; 13: 2913-24
    • (1994) EMBO J , vol.13 , pp. 2913-2924
    • Herschlag, D.1    Khosla, M.2    Tsuchihashi, Z.3
  • 56
    • 0027370258 scopus 로고
    • Protein enhancement of hammerhead ribozyme catalysis
    • Tsuchihashi Z, Khoslo M, Herschlag D. Protein enhancement of hammerhead ribozyme catalysis. Science 1993; 262: 99-102
    • (1993) Science , vol.262 , pp. 99-102
    • Tsuchihashi, Z.1    Khoslo, M.2    Herschlag, D.3


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