Cell cycle-specific and cell type-specific expression of Rb in the developing human retina

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 12, 2006, Pages 5590-5598

  Lee, Thomas C ^a,b   Almeida, Dena ^a   Claros, Nidia ^a   Abramson, David H ^a,c   Cobrinik, David ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b CHILDREN S HOSPITAL LOS ANGELES   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A1; CYCLIN B; CYCLIN D1; CYCLIN A; CYCLIN D; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; RETINOBLASTOMA PROTEIN;

ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL MIGRATION; CELL TYPE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; RETINA; RETINA CONE; RETINA ROD; STEM CELL; TUMOR SUPPRESSOR GENE; CONFOCAL MICROSCOPY; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GESTATIONAL AGE; METABOLISM; PHENOTYPE; PHOTORECEPTOR; PHYSIOLOGY; PRENATAL DEVELOPMENT; RETINA AMACRINE CELL; RETINA BIPOLAR GANGLION CELL; RETINA GANGLION CELL; RETINA HORIZONTAL NERVE CELL;

AMACRINE CELLS; CELL CYCLE; CYCLIN A; CYCLIN B; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GESTATIONAL AGE; HUMANS; MICROSCOPY, CONFOCAL; PHENOTYPE; PHOTORECEPTORS, VERTEBRATE; RETINA; RETINAL BIPOLAR CELLS; RETINAL GANGLION CELLS; RETINAL HORIZONTAL CELLS; RETINOBLASTOMA PROTEIN; STEM CELLS;

EID: 33846657121     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0063     Document Type: Article

References (56)

1. Abramson DH, Schefler AC. Update on retinoblastoma. Retina. 2004;24:828-848.
2. Maat-Kievit JA, Oepkes D, Hartwig NG, Vermeij-Keers C, van Kamp IL, van de Kamp JJ. A large retinoblastoma detected in a fetus at 21 weeks of gestation. Prenat Diagn. 1993;13:377-384.
3. Lohmann DR, Gallie BL. Retinoblastoma: revisiting the model prototype of inherited cancer. Am J Med Genet C Semin Med Genet. 2004;129:23-28.
4. Dyer MA, Bremner R. The search for the retinoblastoma cell of origin. Nat Rev Cancer. 2005;5:91-101.
5. Cobrinik D. Pocket proteins and cell cycle control. Oncogene. 2005;24:2796-2809.
6. Barishak Y. Embryology of the Eye and Its Adnexa. New York: Karger; 2001.
7. 5. In: Smelser G, ed. The Structure of the Eye. New York: Academic Press; 1961:487-505.
8. Donovan SL, Dyer MA. Regulation of proliferation during central nervous system development. Semin Cell Dev Biol. 2005;16:407-421.
9. Livesey FJ, Cepko CL. Vertebrate neural cell-fate determination: lessons from the retina. Nat Rev Neurosci. 2001;2:109-118.
10. O'Brien KM, Schulte D, Hendrickson AE. Expression of photoreceptor- associated molecules during human fetal eye development. Mol Vis. 2003;9:401-409.
11. Provis JM, van Driel D, Billson FA, Russell P. Development of the human retina: patterns of cell distribution and redistribution in the ganglion cell layer. J Comp Neurol. 1985;233:429-451.
12. Gonzalez-Fernandez F, Lopes MB, Garcia-Fernandez JM, et al. Expression of developmentally defined retinal phenotypes in the histogenesis of retinoblastoma. Am J Pathol. 1992;141:363-375.
13. Nork TM, Schwartz TL, Doshi HM, Millecchia LL. Retinoblastoma: cell of origin. Arch Ophthalmol. 1995;113:791-802.
14. Bogenmann E, Lochrie MA, Simon MI. Cone cell-specific genes expressed in retinoblastoma. Science. 1988;240:76-78.
15. Di Polo A, Farber DB. Rod photoreceptor-specific gene expression in human retinoblastoma cells. Proc Natl Acad Sci USA. 1995;92:4016-4020.
16. Fugaro MN, Kiupel M, Montiani-Ferreira F, Hawkins JF, Janovitz EB. Retinoblastoma in the eye of a llama (Llama glama). Vet Ophthalmol. 2005;8:287-290.
17. Syed NA, Nork TM, Poulsen GL, Riis RC, George C, Albert DM. Retinoblastoma in a dog. Arch Ophthalmol. 1997;115:758-763.
18. Robanus-Maandag E, Dekker M, van der Valk M, et al. p107 is a suppressor of retinoblastoma development in pRb-deficient mice. Genes Dev. 1998; 12:1599 -1609.
19. MacPherson D, Sage J, Kim T, Ho D, McLaughlin ME, Jacks T. Cell type-specific effects of Rb deletion in the murine retina. Genes Dev. 2004;18:1681-1694.
20. Zhang J, Schweers B, Dyer MA. The First Knockout Mouse Model of Retinoblastoma. Cell Cycle. 2004;3:952-959.
21. Chen D, Livne-bar I, Vanderluit JL, Slack RS, Agochiya M, Bremner R. Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. Cancer Cell. 2004;5:539-551.
22. Guo Y, Yang K, Harwalkar J, et al. Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis. Oncogene. 2005;24:2599-2612.
23. Dyer MA, Cepko CL. p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. J Neurosci. 2001;21:4259-4271.
24. Levine EM, Close J, Fero M, Ostrovsky A, Reh TA. p27(Kip1) regulates cell cycle withdrawal of late multipotent progenitor cells in the mammalian retina. Dev Biol. 2000;219:299-314.
25. Fung TK, Poon RY. A roller coaster ride with the mitotic cyclins. Semin Cell Dev Biol. 2005;16:335-342.
26. Pines J, Hunter T. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J Cell Biol. 1991;115:1-17.
27. Hendzel MJ, Wei Y, Mancini MA, et al. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma. 1997;106:348-360.
28. Rachel RA, Dolen G, Hayes NL, et al. Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina. J Neurosci. 2002;22:4249-4263.
29. Galli-Resta L, Resta G, Tan SS, Reese BE. Mosaics of islet-1-expressing amacrine cells assembled by short-range cellular interactions. J Neurosci. 1997;17:7831-7838.
30. Xiang M. Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998;197:155-169.
31. Xiang M, Zhou L, Peng YW, Eddy RL, Shows TB, Nathans J. Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells. Neuron. 1993;11:689-701.
32. Hinds JW, Hinds PL. Differentiation of photoreceptors and horizontal cells in the embryonic mouse retina: an electron microscopic, serial section analysis. J Comp Neurol. 1979;187:495-511.
33. Liu W, Wang JH, Xiang M. Specific expression of the LIM/homeodomain protein Lim-1 in horizontal cells during retinogenesis. Dev Dyn. 2000;217:320-325.
34. Edqvist PH, Hallbook F. Newborn horizontal cells migrate bidirectionally across the neuroepithelium during retinal development. Development. 2004;131:1343-1351.
35. Dyer MA, Livesey FJ, Cepko CL, Oliver G. Proxl function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat Genet. 2003;34:53-58.
36. Hoover F, Seleiro EA, Kielland A, Brickell PM, Glover JC. Retinoid X receptor gamma gene transcripts are expressed by a subset of early generated retinal cells and eventually restricted to photoreceptors. J Comp Neurol. 1998;391:204-213.
37. Mori M, Ghyselinck NB, Chambon P, Mark M. Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes. Invest Ophthalmol Vis Sci. 2001;42:1312-1318.
38. Roberts MR, Hendrickson A, McGuire CR, Reh TA. Retinoid X receptor gamma is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina. Invest Ophthalmol Vis Sci. 2005;46:2897-2904.
39. Ng L, Hurley JB, Dierks B, et al. A thyroid hormone receptor that is required for the development of green cone photoreceptors. Nat Genet. 2001;27:94-98.
40. Sjoberg M, Vennstrom B, Forrest D. Thyroid hormone receptors in chick retinal development: differential expression of mRNAs for alpha and N-terminal variant beta receptors. Development. 1992;114:39-47.
41. Swain PK, Hicks D, Mears AJ, et al. Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors. J Biol Chem. 2001;276:36824-36830.
42. Liu IS, Chen JD, Ploder L, et al. Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron. 1994;13:377-393.
43. Bunt-Milam AH, Saari JC. Immunocytochemical localization of two retinoid-binding proteins in vertebrate retina. J Cell Biol. 1983;97:703-712.
44. Close JL, Gumuscu B, Reh TA. Retinal neurons regulate proliferation of postnatal progenitors and Muller glia in the rat retina via TGF beta signaling. Development. 2005;132:3015-3026.
45. Walcott JC, Provis JM. Müller cells express the neuronal progenitor cell marker nestin in both differentiated and undifferentiated human foetal retina. Clin Exp Ophthalmol. 2003;31:246-249.
46. Blackshaw S, Harpavat S, Trimarchi J, et al. Genomic analysis of mouse retinal development. PLoS Biol. 2004;2:E247.
47. Donovan S, Schweers B, Martins R, Johnson D, Dyer MA. Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biol. 2006;4:14.
48. Spencer C, Pajovic S, Devlin H, Dinh QD, Corson TW, Gallie BL. Distinct patterns of expression of the RB gene family in mouse and human retina. Gene Expr Patterns. 2005;5:687-694.
49. Zhang J, Gray J, Wu L, et al. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat Genet. 2004;36:351-360.
50. Szekely L, Uzvolgyi E, Jiang WQ, et al. Subcellular localization of the retinoblastoma protein. Cell Growth Differ. 1991;2:287-295.
51. Ma D, Zhou P, Harbour JW. Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb. J Biol Chem. 2003;278:19358-19366.
52. Liu H, Dibling B, Spike B, Dirlam A, Macleod K. New roles for the RB tumor suppressor protein. Curr Opin Genet Dev. 2004;14;55-64.
53. Jiang Z, Zacksenhaus E, Gallie BL, Phillips RA. The retinoblastoma gene family is differentially expressed during embryogenesis. Oncogene. 1997;14:1789-1797.
54. Classon M, Harlow E. The retinoblastoma tumour suppressor in development and cancer. Nat Rev Cancer. 2002;2:910-917.
55. Calegari F, Huttner WB. An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis. J Cell Sci. 2003;116:4947-4955.
56. Calegari F, Haubensak W, Haffner C, Huttner WB. Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development. J Neurosci. 2005;25:6533-6538.