Analysis of genetic elements regulating the methionine adenosyltransferase gene in Leishmania infantum

Gene

Volumn 389, Issue 2, 2007, Pages 163-173

  García Estrada, Carlos ^a   Pérez Pertejo, Yolanda ^a   Ordóñez, David ^a   Balaña Fouce, Rafael ^a   Reguera, Rosa M ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

Leishmania; MAT2 gene; mRNA stability; Post transcriptional regulation; Promastigotes; Zinc finger protein

Indexed keywords

CYCLOHEXIMIDE; LUCIFERASE; MESSENGER RNA; METHIONINE ADENOSYLTRANSFERASE;

3' UNTRANSLATED REGION; ARTICLE; CELL CYCLE; DNA FLANKING REGION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; LEISHMANIA INFANTUM; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

ANIMALS; CYCLOHEXIMIDE; GENE EXPRESSION REGULATION; GENES, PROTOZOAN; GENOME, PROTOZOAN; LEISHMANIA INFANTUM; LIFE CYCLE STAGES; METHIONINE ADENOSYLTRANSFERASE; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; PROTEIN SYNTHESIS INHIBITORS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA STABILITY; RNA, MESSENGER; RNA, PROTOZOAN; TRANS-SPLICING; TRANSCRIPTION, GENETIC;

LEISHMANIA INFANTUM;

EID: 33846597121     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2006.11.003     Document Type: Article

References (45)

1. Aly R., Argaman M., Pinelli E., and Shapira M. Intergenic sequences from the heat-shock protein 83-encoding gene cluster in Leishmania mexicana amazonensis promote and regulate reporter gene expression in transfected parasites. Gene 127 (1993) 155-163
2. Anderson P., and Kedersha N. RNA granules. J. Cell Biol. 172 (2006) 803-808
3. Beetham J.K., Myung K.S., McCoy J.J., Wilson M.E., and Donelson J.E. Glycoprotein 46 mRNA abundance is post-transcriptionally regulated during development of Leishmania chagasi promastigotes to an infectious form. J. Biol. Chem. 272 (1997) 17360-17366
4. Berberich C., Machado G., Morales G., Carrillo G., Jiménez-Ruiz A., and Alonso C. The expression of the Leishmania infantum KMP-11 protein is developmentally regulated and stage specific. Biochim. Biophys. Acta 1442 (1998) 230-237
5. Boucher N., et al. A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3′-untranslated region element. J. Biol. Chem. 277 (2002) 19511-19520
6. Brengues M., Teixeira D., and Parker R. Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies. Science 310 (2005) 486-489
7. Brittingham A., Miller M.A., Donelson J.E., and Wilson M.E. Regulation of GP63 mRNA stability in promastigotes of virulent and attenuated Leishmania chagasi. Mol. Biochem. Parasitol. 112 (2001) 51-59
8. Brooks D.R., Denise H., Westrop G.D., Coombs G.H., and Mottram J.C. The stage-regulated expression of Leishmania mexicana CPB cysteine proteases is mediated by an intercistronic sequence element. J. Biol. Chem. 276 (2001) 47061-47069
9. Burchmore R.J., and Landfear S.M. Differential regulation of multiple glucose transporter genes in Leishmania mexicana. J. Biol. Chem. 273 (1998) 29118-29126
10. Charest H., Zhang W.W., and Matlashewski G. The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3′-untranslated region. J. Biol. Chem. 271 (1996) 17081-17090
11. Coughlin B.C., Teixeira S.M., Kirchhoff L.V., and Donelson J.E. Amastin mRNA abundance in Trypanosoma cruzi is controlled by a 3′-untranslated region position-dependent cis-element and an untranslated region-binding protein. J. Biol. Chem. 275 (2000) 12051-12060
12. Curotto de Lafaille M.A., Laban A., and Wirth D.F. Gene expression in Leishmania: analysis of essential 5′ DNA sequences. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 2703-2707
13. Fontecave M., Atta M., and Mulliez E. S-adenosylmethionine: nothing goes to waste. Trends Biochem. Sci. 29 (2004) 243-249
14. García-Estrada C., et al. Identification of a gene in Leishmania infantum encoding a protein that contains a SP-RING/MIZ zinc finger domain. Biochim. Biophys. Acta 1629 (2003) 44-52
15. Guimond C., et al. Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays. Nucleic Acids Res. 31 (2003) 5886-5896
16. Hendrickson N., Sifri C.D., Henderson D.M., Allen T., Wirth D.F., and Ullman B. Molecular characterization of the ldmdr1 multidrug resistance gene from Leishmania donovani. Mol. Biochem. Parasitol. 60 (1993) 53-64
17. Keller W., Bienroth S., Lang K.M., and Christofori G. Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3′ processing signal AAUAAA. EMBO J. 10 (1991) 4241-4249
18. Langford C.K., Ewbank S.A., Hanson S.S., Ullman B., and Landfear S.M. Molecular characterization of two genes encoding members of the glucose transporter superfamily in the parasitic protozoan Leishmania donovani. Mol. Biochem. Parasitol. 55 (1992) 51-64
19. LeBowitz J.H., Smith H.Q., Rusche L., and Beverley S.M. Coupling of poly(A) site selection and trans-splicing in Leishmania. Genes Dev. 7 (1993) 996-1007
20. Lu S.C. S-Adenosylmethionine. Int. J. Biochem. Cell Biol. 32 (2000) 391-395
21. Lu S.C., and Mato J.M. Role of methionine adenosyltransferase and S-adenosyl-methionine in alcohol-associated liver cancer. Alcohol 35 (2005) 227-234
22. Mato J.M., Corrales F.J., Lu S.C., and Ávila M.A. S-Adenosylmethionine: a control switch that regulates liver function. FASEB J. 16 (2002) 15-26
23. McCoy J.J., Beetham J.K., Ochs D.E., Donelson J.E., and Wilson M.E. Regulatory sequences and a novel gene in the msp (GP63) gene cluster of Leishmania chagasi. Mol. Biochem. Parasitol. 95 (1998) 251-265
24. Muller S., Liebau E., Walter R.D., and Krauth-Siegel R.L. Thiol-based redox metabolism of protozoan parasites. Trends Parasitol. 20 (2003) 58-59
25. Nilsen T.W. Trans-splicing: an update. Mol. Biochem. Parasitol. 73 (1995) 1-6
26. Nourbakhsh F., Uliana S.R., and Smith D.F. Characterization and expression of a stage-regulated gene of Leishmania major. Mol. Biochem. Parasitol. 76 (1996) 201-213
27. Nozaki T., Ali V., and Tokoro M. Sulphur-containing amino acid metabolism in parasitic protozoa. Adv. Parasitol. 60 (2005) 1-99
28. Pérez-Pertejo Y., Reguera R.M., Ordóñez D., and Balaña-Fouce R. Characterization of a methionine adenosyltransferase overexpressing strain in the trypanosomatid Leishmania donovani. Biochim. Biophys. Acta 1760 (2006) 10-19
29. Quijada L., Soto M., Alonso C., and Requena J.M. Analysis of post-transcriptional regulation operating on transcription products of the tandemly linked Leishmania infantum hsp70 genes. J. Biol. Chem. 272 (1997) 4493-4499
30. Quijada L., Soto M., Alonso C., and Requena J.M. Identification of a putative regulatory element in the 3′-untranslated region that controls expression of HSP70 in Leishmania infantum. Mol. Biochem. Parasitol. 110 (2000) 79-91
31. Ramamoorthy R., Swihart K.G., McCoy J.J., Wilson M.E., and Donelson J.E. Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes. J. Biol. Chem. 270 (1995) 12133-12139
32. Ramamoorthy R., Donelson J.E., and Wilson M.E. 5′ sequences essential for trans-splicing of msp (gp63) RNAs in Leishmania chagasi. Mol. Biochem. Parasitol. 77 (1996) 65-76
33. Reguera R.M., et al. Cloning expression and characterization of methionine adenosyltransferase in Leishmania infantum promastigotes. J. Biol. Chem. 277 (2002) 3158-3167
34. Roberts S.C., Swihart K.G., Agey M.W., Ramamoorthy R., Wilson M.E., and Donelson J.E. Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi. Mol. Biochem. Parasitol. 62 (1993) 157-171
35. Sambrook J., Fritsch E.F., and Maniatis T. Molecular Cloning (A Laboratory Manual) (1989), Cold Spring Harbor Laboratory Press
36. Soto M., Requena J.M., García M., Gómez L.C., Navarrete I., and Alonso C. Genomic organization and expression of two independent gene arrays coding for two antigenic acidic ribosomal proteins of Leishmania. J. Biol. Chem. 268 (1993) 21835-21843
37. Stiles J.K., Hicock P.I., Shah P.H., and Meade J.C. Genomic organization, transcription, splicing and gene regulation in Leishmania. Ann. Trop. Med. Parasitol. 93 (1999) 781-807
38. Teixeira S.M. Control of gene expression in Trypanosomatidae. Braz. J. Med. Biol. Res. 31 (1998) 1503-1516
39. Teixeira S.M.R., Kirchhoff L.V., and Donelson J.E. Post-transcriptional elements regulating expression of mRNAs from the amastin/tuzin gene cluster of Trypanosoma cruzi. J. Biol. Chem. 270 (1995) 22586-22594
40. Teixeira D., Sheth U., Valencia-Sánchez M.A., Brengues M., and Parker R. Processing bodies require RNA for assembly and contain untranslating mRNAs. RNA 11 (2005) 371-382
41. Vanhamme L., and Pays E. Control of gene expression in trypanosomes. Microbiol. Rev. 59 (1995) 223-240
42. Wahle E., and Ruegsegger U. 3′-End processing of pre-mRNA in eukaryotes. FEMS Microbiol. Rev. 23 (1999) 277-295
43. Wilson M.E., Paetz K.E., Ramamoorthy R., and Donelson J.E. The effect of ongoing protein synthesis on the steady state levels of Gp63 RNAs in Leishmania chagasi. J. Biol. Chem. 268 (1993) 15731-15736
44. Wu Y., El Fakhry Y., Sereno D., Tamar S., and Papadopoulou B. A new developmentally regulated gene family in Leishmania amastigotes encoding a homolog of amastin surface proteins. Mol. Biochem. Parasitol. 110 (2000) 345-357
45. Zarley J.H., Britigan B.E., and Wilson M.E. Hydrogen peroxide-mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock. J. Clin. Invest. 88 (1991) 1511-1521