Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937

BMC Cancer

Volumn 6, Issue , 2006, Pages

  Nyaga, Simon G ^a   Lohani, Althaf ^a   Jaruga, Pawel ^b,c   Trzeciak, Andrzej R ^a   Dizdaroglu, Miral ^d   Evans, Michele K ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b University of Marylandw Baltimore County   (United States)

^c NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^d NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; CELL PROTEIN; GENOMIC DNA; HYDROGEN PEROXIDE; MESSENGER RNA; MITOCHONDRIAL ENZYME; NUCLEOSIDE; OLIGONUCLEOTIDE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATIVE STRESS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; UPREGULATION; WESTERN BLOTTING;

BASE SEQUENCE; BREAST NEOPLASMS; CARCINOMA, DUCTAL; CELL EXTRACTS; CELL LINE, TUMOR; CELL NUCLEUS; DNA PRIMERS; DNA REPAIR; FEMALE; GUANINE; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; OLIGODEOXYRIBONUCLEOTIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; TRANSFECTION;

EID: 33846577358     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-6-297     Document Type: Article

References (52)

1. Dizdaroglu M Rao G Halliwell B Gajewski E Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions Arch Biochem Biophys 1991 285 2 317-324 10.1016/ 0003-9861(91)90366-Q 1654771
2. Grollman AP Moriya M Mutagenesis by 8-oxoguanine: An enemy within Trends Genet 1993 9 7 246-249 10.1016/0168-9525(93)90089-Z 8379000
3. Tajiri T Maki H Sekiguchi M Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli Mutat Res 1995 336 3 257-267 7739614
4. Hazra TK Hill JW Izumi T Mitra S Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions Prog Nucleic Acid Res Mol Biol 2001 68 193-205 11554297
5. Michaels ML Miller JH The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) J Bacteriol 1992 174 20 6321-6325 207574 1328155
6. Radicella JP Dherin C Desmaze C Fox MS Boiteux S Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae Proc Natl Acad Sci U S A 1997 94 15 8010-8015 21547 9223305 10.1073/pnas.94.15.8010
7. Nash HM Bruner SD Scharer OD Kawate T Addona TA Spooner E Lane WS Verdine GL Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily Curr Biol 1996 6 8 968-980 10.1016/S0960-9822(02)00641-3 8805338
8. Rosenquist TA Zharkov DO Grollman AP Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase Proc Natl Acad Sci U S A 1997 94 14 7429-7434 23838 9207108 10.1073/pnas.94.14.7429
9. Dherin C Radicella JP Dizdaroglu M Boiteux S Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations Nucleic Acids Res 1999 27 20 4001-4007 148667 10497264 10.1093/nar/27.20.4001
10. Slupphaug G Kavli B Krokan HE The interacting pathways for prevention and repair of oxidative DNA damage Mutat Res 2003 531 1-2 231-251 14637258
11. Dianov G Bischoff C Piotrowski J Bohr VA Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts J Biol Chem 1998 273 50 33811-33816 10.1074/jbc.273.50.33811 9837971
12. Cooke MS Evans MD Dizdaroglu M Lunec J Oxidative DNA damage: Mechanisms, mutation, and disease Faseb J 2003 17 10 1195-1214 10.1096/fj.02-0752rev 12832285
13. Malins DC Haimanot R Major alterations in the nucleotide structure of DNA in cancer of the female breast Cancer Res 1991 51 19 5430-5432 1655250
14. Malins DC Holmes EH Polissar NL Gunselman SJ The etiology of breast cancer. Characteristic alteration in hydroxyl radical-induced DNA base lesions during oncogenesis with potential for evaluating incidence risk Cancer 1993 71 10 3036-3043 10.1002/1097-0142(19930515) 71:10<3036::AID-CNCR2820711025>3.0.CO;2-P 8387875
15. Olinski R Zastawny T Budzbon J Skokowski J Zegarski W Dizdaroglu M DNA base modifications in chromatin of human cancerous tissues FEBS Lett 1992 309 2 193-198 10.1016/0014-5793(92)81093-2 1324197
16. Parshad R Price FM Bohr VA Cowans KH Zujewski JA Sanford KK Deficient DNA repair capacity, a predisposing factor in breast cancer Br J Cancer 1996 74 1 1-5 8679441
17. Mambo E Nyaga SG Bohr VA Evans MK Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines Cancer Res 2002 62 5 1349-1355 11888904
18. Abbott DW Thompson ME Robinson-Benion C Tomlinson G Jensen RA Holt JT BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair J Biol Chem 1999 274 26 18808-18812 10.1074/jbc.274.26.18808 10373498
19. Trzeciak AR Nyaga SG Jaruga P Lohani A Dizdaroglu M Evans MK Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145 Carcinogenesis 2004 25 8 1359-1370 10.1093/carcin/bgh144 15044326
20. Nyaga SG Bohr VA Characterization of specialized mtDNA glycosylases Methods Mol Biol 2002 197 227-244 12013799
21. Miller SA Dykes DD Polesky HF A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 1988 16 3 1215 334765 3344216 10.1093/nar/16.3.1215
22. Jaruga P Theruvathu J Dizdaroglu M Brooks PJ Complete release of (5'S)-8,5'-cyclo-2'-deoxyadenosine from dinucleotides, oligodeoxynucleotides and DNA, and direct comparison of its levels in cellular DNA with other oxidatively induced DNA lesions Nucleic Acids Res 2004 32 11 e87 443555 15215337 10.1093/nar/gnh087
23. Parker AR O'Meally RN Oliver DH Hua L Nelson WG DeWeese TL Eshleman JR 8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells Cancer Res 2002 62 24 7230-7233 12499263
24. Dianov G Bischoff C Sunesen M Bohr VA Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells Nucleic Acids Res 1999 27 5 1365-1368 148325 9973627 10.1093/nar/27.5.1365
25. Selzer RR Nyaga S Tuo J May A Muftuoglu M Christiansen M Citterio E Brosh RM Jr. Bohr VA Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells Nucleic Acids Res 2002 30 3 782-793 100288 11809892 10.1093/nar/30.3.782
26. Tuo J Jaruga P Rodriguez H Bohr VA Dizdaroglu M Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress Faseb J 2003 17 6 668-674 10.1096/fj.02-0851com 12665480
27. Mambo E Chatterjee A de Souza-Pinto NC Mayard S Hogue BA Hoque MO Dizdaroglu M Bohr VA Sidransky D Oxidized guanine lesions and hOgg1 activity in lung cancer Oncogene 2005 24 28 4496-4508 10.1038/ sj.onc.1208669 15856018
28. Chatterjee A Mambo E Osada M Upadhyay S Sidransky D The effect of p53-RNAi and p53 knockout on human 8-oxoguanine DNA glycosylase (hOgg1) activity Faseb J 2006 20 1 112-114 16293709
29. Hill JW Hazra TK Izumi T Mitra S Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: Potential coordination of the initial steps in base excision repair Nucleic Acids Res 2001 29 2 430-438 29662 11139613 10.1093/nar/29.2.430
30. Vidal AE Hickson ID Boiteux S Radicella JP Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: Bypass of the AP lyase activity step Nucleic Acids Res 2001 29 6 1285 1292-29755 11238994 10.1093/nar/29.6.1285
31. Saitoh T Shinmura K Yamaguchi S Tani M Seki S Murakami H Nojima Y Yokota J Enhancement of OGG1 protein AP lyase activity by increase of APEX protein Mutat Res 2001 486 1 31-40 11356334
32. Mokkapati SK Wiederhold L Hazra TK Mitra S Stimulation of DNA glycosylase activity of OGG1 by NEIL1: Functional collaboration between two human DNA glycosylases Biochemistry 2004 43 36 11596-11604 10.1021/ bi049097i 15350146
33. Jaruga P Birincioglu M Rosenquist TA Dizdaroglu M Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA Biochemistry 2004 43 50 15909-15914 10.1021/bi048162l 15595846
34. Krokan HE Drablos F Slupphaug G Uracil in DNA--occurrence, consequences and repair Oncogene 2002 21 58 8935-8948 10.1038/sj.onc.1205996 12483510
35. Thomas D Scot AD Barbey R Padula M Boiteux S Inactivation of OGG1 increases the incidence of G. C→T. A transversions in Saccharomyces cerevisiae: Evidence for endogenous oxidative damage to DNA in eukaryotic cells Mol Gen Genet 1997 254 2 171-178 10.1007/s004380050405 9108279
36. Klungland A Rosewell I Hollenbach S Larsen E Daly G Epe B Seeberg E Lindahl T Barnes DE Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage Proc Natl Acad Sci U S A 1999 96 23 13300-13305 23942 10557315 10.1073/pnas.96.23.13300
37. Osterod M Hollenbach S Hengstler JG Barnes DE Lindahl T Epe B Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice Carcinogenesis 2001 22 9 1459-1463 10.1093/carcin/22.9.1459 11532868
38. Minowa O Arai T Hirano M Monden Y Nakai S Fukuda M Itoh M Takano H Hippou Y Aburatani H Masumura K Nohmi T Nishimura S Noda T Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice Proc Natl Acad Sci U S A 2000 97 8 4156-4161 18180 10725358 10.1073/ pnas.050404497
39. Li D Zhang W Zhu J Chang P Sahin A Singletary E Bondy M Hazra T Mitra S Lau SS Shen J DiGiovanni J Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer Mol Carcinog 2001 31 4 214-223 10.1002/mc.1056 11536371
40. Dobson AW Grishko V LeDoux SP Kelley MR Wilson GL Gillespie MN Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death Am J Physiol Lung Cell Mol Physiol 2002 283 1 L205-10 12060578
41. Rachek LI Grishko VI Musiyenko SI Kelley MR LeDoux SP Wilson GL Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria J Biol Chem 2002 277 47 44932-44937 10.1074/jbc.M208770200 12244119
42. Audebert M Radicella JP Dizdaroglu M Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein Nucleic Acids Res 2000 28 14 2672-2678 102664 10908322 10.1093/ nar/28.14.2672
43. Hill JW Evans MK Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylase Nucleic Acids Res 2006 34 5 1620-1632 1405821 16549874 10.1093/nar/gkl060
44. Richter C Park JW Ames BN Normal oxidative damage to mitochondrial and nuclear DNA is extensive Proc Natl Acad Sci U S A 1988 85 17 6465-6467 281993 3413108 10.1073/pnas.85.17.6465
45. Starcevic SL Diotte NM Zukowski KL Cameron MJ Novak RF Oxidative DNA damage and repair in a cell lineage model of human proliferative breast disease (PBD) Toxicol Sci 2003 75 1 74-81 10.1093/toxsci/kfg154 12805649
46. Achanta G Huang P Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents Cancer Res 2004 64 17 6233-6239 10.1158/0008-5472.CAN-04-0494 15342409
47. Tomlinson GE Chen TT Stastny VA Virmani AK Spillman MA Tonk V Blum JL Schneider NR Wistuba Shay JW Minna JD Gazdar AF Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier Cancer Res 1998 58 15 3237-3242 9699648
48. Koonin EV Altschul SF Bork P BRCA1 protein products... Functional motifs Nat Genet 1996 13 3 266-268 10.1038/ng0796-266 8673121
49. Bork P Hofmann K Bucher P Neuwald AF Altschul SF Koonin EV A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins Faseb J 1997 11 1 68-76 9034168
50. Callebaut I Mornon JP From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair FEBS Lett 1997 400 1 25-30 10.1016/ S0014-5793(96)01312-9 9000507
51. Rodriguez M Yu X Chen J Songyang Z Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains J Biol Chem 2003 278 52 52914-52918 10.1074/jbc.C300407200 14578343
52. Shen SX Weaver Z Xu X Li C Weinstein M Chen L Guan XY Ried T Deng CX A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability Oncogene 1998 17 24 3115-3124 10.1038/sj.onc.1202243 9872327