Deficient DNA repair capacity, a predisposing factor in breast cancer

British Journal of Cancer

Volumn 74, Issue 1, 1996, Pages 1-5

  Parshad, R ^a   Price, F M ^b   Bohr, V A ^c   Cowans, K H ^b   Zujewski, J A ^b   Sanford, K K ^b,d  

^a HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Breast cancer; Chromatid breaks; DNA repair

Indexed keywords

CYTARABINE; DNA; PHYTOHEMAGGLUTININ;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CASE REPORT; CELL MUTANT; CHO CELL; CHROMATID; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; DNA TRANSFECTION; FAMILIAL CANCER; HUMAN; HUMAN CELL; LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET IRRADIATION; X IRRADIATION; XERODERMA PIGMENTOSUM;

EID: 0030015544     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.307     Document Type: Article

References (39)

1. BULLER RE, ANDERSON B, CONNOR JP AND ROBINSON R. (1993), Familial ovarian cancer. Gynecol. Oncol., 51, 160-166.
2. COLLINS AR. (1993). Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res., 293, 99-118.
3. 2 chromatid radiosensitivity in dyskeratosis congenita fibroblasts. Am. J. Human Genet., 46, 350-357.
4. EASTON DF. (1994). Cancer risks in A T heterozygotes. Int. J. Radiat. Biol., 64 (suppl.), S, 177-182.
5. EVANS MK, ROBBINS JH, GANGES MB, TARONE RE, NAIRN RS AND BOHR VA. (1993). Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D and F. J. Biol. Chem., 268, 4839-4847.
6. EYFJÖRD JE, THORLACIUS S, STEINDARSDOTTIR M, VALGARDSDOTTIR R, ÖGMUNDSDOTTIR HM AND ANAMTHAWAT-JONSSON K. (1995). p53 abnormalities and genomic instability in primary human breast carcinomas. Cancer Res., 55, 646-651.
7. FRIEDBERG EC, WALKER GC AND SIEDE W. (1995). DNA Repair and Mutagenesis. ASM Press: Washington, DC.
8. 2 chromatid radiosensitivity, an early stage in the neoplastic transformation of human epidermal keratinocytes in culture. Cancer Res., 47, 1390-1397.
9. HOEIJMAKERS JHJ AND BOOTSMA D. (1994). Incision for excision. Nature, 371, 654-655.
10. KNIGHT RB, PARSHAD R, PRICE FM, TARONE RE AND SANFORD KK. (1993). X-ray-induced chromatid damage in relation to DNA repair and cancer incidence in family members. Int. J. Cancer, 54, 589-593.
11. KRAEMER KH, COON HG, PETINGA RA, BARRETT SF, RAHE A AND ROBBINS JH. (1975). Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc. Natl Acad. Sci., USA, 72, 59-63.
12. 2 ataxia-telangectasia cells exposed to x-rays and ara-A. Int. J. Radiat. Biol., 55, 71-84.
13. 2 studies of cell cycle. Mutat. Res., 69, 293-305.
14. PANDITA TK AND HITTELMAN WN. (1995). Evidence of a chromatin basis for increased mutagen sensitivity associated with multiple primary malignancies of the head and neck. Int. J. Cancer, 61, 738-743.
15. 2 phase x-irradiation of cells from cancer-prone individuals implicates deficiency in DNA repair. Proc. Natl Acad. Sci. USA, 80, 5612-5616.
16. 2 chromosomal radiosensitivity of ataxia-telangiectasia heterozygotes. Cancer Genet. Cytoget., 14, 163-168.
17. 2-phase x-irradiation in relation to DNA repair and radiosensitivity in a cancer-prone family with Li Fraumeni syndrome. Radiat. Res., 136, 236-240.
18. 2 phase. Mutat. Res., 294, 149-155.
19. 2 phase with progression from benign to malignant state in a line of human skin keratinocytes transfected with ras oncogene. Carcinogenesis, 15, 33-37.
20. PETINGA RA, ANDREWS AD, TARONE RE AND ROBBINS JH. (1977). Typical xeroderma pigmentosum complementation group A fibroblasts have detectable ultraviolet light-induced unscheduled DNA synthesis. Biochim. Biophys. Acta, 479, 400-419.
21. PRESTON GA, PAYNE HS AND PRESTON RJ. (1992). Isolation and characterization of a 1-β-D-arabinofuranosylcytosine-resistant Chinese hamster ovary cell mutant that is also x-ray sensitive and is non-complementary with ataxia telangiectasia cells. Cancer Res., 52, 319-329.
22. PRESTON RJ. (1980). The effect of cytosine arabinoside on the frequency of x-ray-induced chromosome aberrations in normal human leukocytes. Mutat. Res., 69, 71-79.
23. ROBBINS JH, KRAEMER KH, LUTZNER MA, FESTOFF BW AND COON HG. (1974). An inherited disease with sun sensitivity, multiple cutaneous neoplasms and abnormal DNA repair. Ann. Intern. Med., 80, 221-248.
24. 2 chromatid radiation damage in familial dysplastic nevus syndrome. Lancet, 2, 1111-1116.
25. 2 chromatin radiosensitivity in predisposition to cancer. Int. J. Radiat. Biol., 55, 963-981.
26. 2 phase x-irradiation, a marker of the ataxia-telangiectasia gene. J. Natl Cancer Inst., 82, 1050-1054.
27. SANFORD KK, PARSHAD R, PRICE FM, RHIM JS, STAMPFER M AND PARSHAD R. (1992). Role of DNA repair in malignant neoplastic transformation of human mammary epithelial cells in culture. Carcinogenesis, 13, 1137-1141.
28. SANFORD KK, PARSHAD R, PRICE FM, TARONE RE AND SCHAPIRO MB. (1993). X-ray-induced chromatid damage in cells from Down syndrome and Alzheimer disease patients in relation to DNA repair and cancer proneness. Cancer Genet. Cytogenet. 70, 25-30.
29. SATOH MS, JONES CJ, WOOD RD AND LINDAHL RT. (1993). DNA excision-repair defect in xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions. Proc. Natl Acad. Sci. USA, 90, 6335-6339.
30. SCOTT D, SPREADBOROUGH A, LEVINE E AND ROBERTS SA. (1994). Genetic predisposition in breast cancer. Lancet, 344, 1444.
31. SMITH, ML, CHEN I-T, ZHAN Q, O'CONNOR PM AND FORNACE AJ, JR. (1995). Involvement of the p53 tumor suppressor in repair of UV-type DNA damage. Oncogene, 10, 1053-1059.
32. SQUIRES S AND JOHNSON RT. (1988). Kinetic analysis of UV-induced incision discriminates between fibroblasts from different xeroderma pigmentosum complementation groups, XPA heterozygotes and normal individuals. Mutat. Res., 193, 181-192.
33. SRIVASTAVA S, ZOU Z, PIROLLO K, BLATTNER W AND CHANG EH. (1990). Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li - Fraumeni syndrome. Nature, 348, 747-749.
34. 2 phase x-irradiation in lymphoblastoid cells from Gardner's syndrome. Carcinogenesis, 11, 1425-1428.
35. TROELSTRA C, VAN GOOL A, DE WIT J, VERMEULEN W, BOOTSMA D AND HOEIJMAKERS HJ. (1992). ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell, 71, 939-953.
36. TROELSTRA C, HESEN W, BOOTSMA D AND HOEIJMAKERS JHJ. (1993). Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B. Nucleic Acids Res., 21, 419-426.
37. VERMUELEN W, SCOTT RJ, RODGERS S, MÜLLER HJ, COLE J, ARLETT CF, KLEIJER WJ, BOOTSMA D, HOEIJMAKERS JHJ AND WEEDA G. (1994). Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3. Am. J. Human. Genet., 54, 191-200.
38. WANG XW, YEH H, SCHAEFFER L, ROY R, MONCOLLIN V, EGLY J-M, WANG Z, FRIEDBERG EC, EVANS MK, TAFFE BG, BOHR VA, WEEDA G, HOEIJMAKER JHJ, FORRESTER K AND HARRIS CC. (1995). p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature Genet., 10, 188-195.
39. WEEDA D, VAN HAM RCA, VERMEULEN W, BOOTSMA D, VAN DER EB AJ AND HOEIJMAKERS HJ. (1990). A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome. Cell, 62, 777-791.