Disease induction by human microbial pathogens in plant-model systems: potential, problems and prospects

Drug Discovery Today

Volumn 12, Issue 3-4, 2007, Pages 167-173

  van Baarlen, Peter ^a   van Belkum, Alex ^b   Thomma, Bart P H J ^c  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBIOTIC AGENT; CAMALEXIN; GLUCOSINOLATE; SALICYLIC ACID;

ARABIDOPSIS; BACILLUS CEREUS; CAMPYLOBACTER; CLOSTRIDIUM BOTULINUM; DISEASE MODEL; ENDOCARDITIS; ESCHERICHIA COLI; EUKARYOTE; GENETIC MODEL; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; NONHUMAN; PATHOGENICITY; PSEUDOMONAS AERUGINOSA; REVIEW; SALMONELLA; SHIGELLA; STAPHYLOCOCCUS AUREUS; SYMPTOMATOLOGY;

ANIMAL TESTING ALTERNATIVES; ANIMALS; ARABIDOPSIS; BACTERIA; HUMANS; MODELS, BIOLOGICAL; PLANT DISEASES; PLANTS;

EID: 33846573774     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2006.12.007     Document Type: Review

References (80)

1. Whittaker R.H. On the broad classification of organisms. Q. Rev. Biol. 34 (1959) 210-226
2. Beuchat L.R. Ecological factors influencing survival and growth of human pathogens on raw fruits and vegetables. Microbes Infect. 4 (2002) 413-423
3. Brandl M.T. Fitness of human enteric pathogens on plants and implications for food safety. Annu. Rev. Phytopathol. 44 (2006) 367-392
4. Prithiviraj B., et al. Plant models for animal pathogenesis. Cell. Microbiol. 7 (2005) 315-324
5. Pang P.P., and Meyerowitz E.M. Arabidopsis thaliana: a model system for plant molecular biology. Nat. Rev. Biotechnol. 5 (1987) 1177-1181
6. Meinke D.W., et al. Arabidopsis thaliana: a model plant for genome analysis. Science 662 (1998) 679-682
7. Alonso J.M., et al. Genome-wide insertional mutagenesis of Arabidopsis thaliana. Science 301 (2003) 653-657
8. Abramovitch R.B., et al. Bacterial elicitation and evasion of plant innate immunity. Nat. Rev. Mol. Cell Biol. 7 (2006) 601-611
9. Ausubel F.M. Are innate immune signaling pathways in plants and animals conserved?. Nat. Immunol. 6 (2005) 973-979
10. Thomma B.P.H.J., et al. Plant defensins. Planta 216 (2002) 193-202
11. Mygind P.H., et al. Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature 437 (2005) 975-980
12. Cole A.M., et al. Determinants of Staphylococcus aureus nasal carriage. Clin. Diagn. Lab. Immunol. 8 (2001) 1064-1069
13. Thomma B.P.H.J., et al. Separate jasmonate-dependent and salicylate- dependent defense response pathways in Arabidopsis are essential for resistance to distinct microbial pathogens. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 15107-15111
14. Rubin G.M., et al. Comparative genomics of the eukaryotes. Science 287 (2000) 2204-2215
15. Nürnberger T., et al. Innate immunity in plants and animals: striking similarities and obvious differences. Immunol. Rev. 198 (2004) 249-266
16. Medzhitov R., and Janeway C.A. Decoding the patterns of self and nonself by the innate immune system. Science 296 (2002) 298-300
17. Bhattacharjee S., et al. The malarial host-targeting signal is conserved in the Irish potato famine pathogen. PLoS Pathog. 2 (2006) 453-465
18. Lemaitre B., et al. Drosophila host defence: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 14614-14619
19. Medzhitov R., et al. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
20. Song W.-Y., et al. A receptor kinase-like protein encoded by the rice disease resistance geneXa27. Science 270 (1995) 1804-1806
21. Jones D.A., et al. Isolation of the tomato Cf-9 gene for resistance to Cladosporium fulvum by transposon tagging. Science 266 (1994) 789-793
22. Martinon F., and Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26 (2005) 447-454
23. Shiu S.-H., and Bleecker A.B. Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 10763-10768
24. Hershko A., and Ciechanover A. The ubiquitin system. Annu. Rev. Biochem. 67 (1998) 425-479
25. Janjusevic R., et al. A bacterial inhibitor of host programmed cell death defences is an E3 ubiquitin ligase. Science 311 (2006) 222-226
26. Abramovitch R.B., et al. Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death. EMBO J. 22 (2003) 60-69
27. Cao H., et al. Common mechanisms for pathogens of plants and animals. Annu. Rev. Phytopathol. 39 (2001) 259-284
28. Casadevall A. Host as the variable: model hosts approach the immunological asymptote. Infect. Immun. 73 (2005) 3829-3832
29. Plotnikova J.M., et al. Pathogenesis of the human opportunistic pathogen Pseudomonas aeruginosa PA14 in Arabidopsis. Plant Physiol. 124 (2001) 1766-1774
30. Rahme L.G., et al. Common virulence factors for bacterial pathogenicity in plants and animals. Science 268 (1995) 1899-1902
31. Rahme L.G., et al. Plants and animals share functionally common bacterial virulence factors. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 8815-8821
32. Delaney T.P., et al. A central role of salicylic acid in plant disease resistance. Science 266 (1994) 1247-1250
33. Thomma B.P.H.J., et al. The complexity of disease signaling in Arabidopsis. Curr. Opin. Immunol. 13 (2001) 63-68
34. Prithiviraj B., et al. Down regulation of virulence factors of Pseudomonas aeruginosa by salicylic acid attenuates its virulence on Arabidopsis thaliana and Caenorhabditis elegans. Infect. Immun. 73 (2005) 5319-5328
35. Prithiviraj B., et al. Staphylococcus aureus pathogenicity on Arabidopsis thaliana is mediated either by a direct effect of salicylic acid on the pathogen or by SA-dependent, NPR1-independent host responses. Plant J. 42 (2005) 417-432
36. Kupferwasser L.I., et al. Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects. Circulation 99 (1999) 2791-2797
37. Karabay O., et al. A new effect of acetylsalicylic acid? Significantly lower prevalence of nasal carriage of Staphylococcus aureus among patients receiving orally administered acetylsalicylic acid. Infect. Control Hosp. Epidemiol. 27 (2006) 318-319
38. Osbourn A.E., et al. Dissecting plant secondary metabolism - constitutive chemical defences in cereals. New Phytol. 159 (2003) 101-108
39. Dixon R.A. Natural products and plant disease resistance. Nature 411 (2001) 843-847
40. Hahlbrock K., et al. Non-self recognition, transcriptional reprogramming, and secondary metabolite accumulation during plant/pathogen interactions. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 14569-14576
41. Thomma B.P.H.J., et al. Deficiency in phytoalexin production causes enhanced susceptibility of Arabidopsis thaliana to the fungus Alternaria brassicicola. Plant J. 19 (1999) 163-171
42. Kliebenstein D.J., et al. Secondary metabolites influence Arabidopsis/Botrytis interactions: variation in host production and pathogen sensitivity. Plant J. 44 (2005) 25-36
43. Tierens K.F.M.-J., et al. Study of the role of antimicrobial glucosinolate-derived isothiocyanates in resistance of Arabidopsis to microbial pathogens. Plant Physiol. 125 (2001) 1688-1699
44. Brader G., et al. Altering glucosinolate profiles modulates disease resistance in plants. Plant J. 46 (2006) 758-767
45. Zhao J., et al. Elicitor signal transduction leading to production of plant secondary metabolites. Biotechnol. Adv. 23 (2005) 283-333
46. Schuhegger R., et al. CYP71B15 (PAD3) catalyzes the final step in camalexin biosynthesis. Plant Physiol. 141 (2006) 1248-1254
47. Wolfgang M.C., et al. Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 8484-8489
48. Smith E.E., et al. Genetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 8487-8492
49. Oliver A., et al. High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. Science 288 (2000) 1251-1254
50. Brown N.F., et al. Crossing the line: selection and evolution of virulence traits. Plos Pathog. 2 (2006) e42
51. Rahme L.G., et al. Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13245-13250
52. Gill S.R., et al. Metagenomic analysis of the human distal gut microbiome. Science 312 (2006) 1355-1359
53. Thomma B.P.H.J. Alternaria spp: from general saprophyte to specific parasite. Mol. Plant Pathol. 4 (2003) 225-236
54. Abbas H.K., et al. Fumonisin- and AAL-toxin-induced disruption of sphingolipid metabolism with accumulation of free sphingoid bases. Plant Physiol. 106 (1994) 1085-1093
55. Chen J., et al. Production of the mycotoxin fumonisin B1 by Alternaria alternata f.sp. lycopersici. Appl. Environ. Microbiol. 58 (1992) 3928-3931
56. Gilchrist D.G., et al. Genetic and physiological response to fumonisins and AAL-toxin by intact tissue of a higher plant. Mycopathologia 117 (1992) 57-64
57. Wang H., et al. Apoptosis: a functional paradigm for programmed plant cell death induced by a hostselective phytotoxin and invoked during development. Plant Cell 8 (1996) 375-391
58. Wang W., et al. Fumonisins and Alternaria alternata lycopersici toxins: sphinganine analog mycotoxins induce apoptosis in monkey kidney cells. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 3461-3465
59. Lincoln J.E., et al. Expression of the antiapoptotic baculovirus p35 gene in tomato blocks programmed cell death and provides broadspectrum resistance to disease. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 15217-15221
60. Bratton D.L., et al. Staphylococcal toxic shock syndrome toxin-1 inhibits monocyte apoptosis. J. Allergy Clin. Immunol. 103 (1999) 895-900
61. Mempel M., et al. Invasion of human keratinocytes by Staphylococcus aureus and intracellular bacterial persistence represent haemolysin-independent virulence mechanisms that are followed by features of necrotic and apoptotic keratinocyte cell death. Br. J. Dermatol. 146 (2002) 943-951
62. Gechev T.S., et al. An extensive microarray analysis of AAL-toxin-induced cell death in Arabidopsis thaliana brings new insights into the complexity of programmed cell death in plants. Cell. Mol. Life Sci. 61 (2004) 1185-1197
63. Kundu S., et al. Plants, humans and hemoglobins. Trends Plant Sci. 8 (2003) 387-393
64. Cossard E., et al. Comparative adherence to human A549 cells, plant fibronectin-like protein, and polystyrene surfaces of four Pseudomonas fluorescens strains from different ecological origin. Can. J. Microbiol. 51 (2005) 811-815
65. Zhu J.K., et al. A higher plant extracellular vitronectin-like adhesion protein is related to the translational elongation factor-1 alpha. Plant Cell 6 (1994) 393-404
66. Ringli C., et al. Glycine-rich proteins as structural components of plant cell walls. Cell. Mol. Life Sci. 58 (2001) 1430-1441
67. Foster T.J. Immune evasion by staphylococci. Nat. Rev. Microbiol. 3 (2005) 948-958
68. Murray R.J. Recognition and management of Staphylococcus aureus toxin-mediated disease. Intern. Med. J. 35 suppl. (2005) S106-S119
69. Rooijakkers S.H., et al. Staphylococcal innate immune evasion. Trends Microbiol. 13 (2005) 596-601
70. Sibbald M.J., et al. Mapping the pathways to staphylococcal pathogenesis by comparative secretomics. Microbiol. Mol. Biol. Rev. 70 (2006) 755-788
71. Greenberg J.T., and Ausubel F.M. Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging. Plant J. 4 (1993) 327-341
72. Asai T., et al. Fumonisin B1-induced cell death in Arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. Plant Cell 12 (2000) 1823-1836
73. van Baarlen, P. et al. Histochemical and genetic analysis of host and non-host interactions of Arabidopsis with three Botrytis species: an important role for cell death control. Mol. Plant Pathol. (in press)
74. He J., et al. The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2530-2535
75. Joardar V., et al. Lineage-specific regions in Pseudomonas syringae pv tomato DC3000. Mol. Plant Pathol. 6 (2005) 53-64
76. Ochman H., et al. Identification of a pathogenicity island required for Salmonella survival in host cells. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 7800-7804
77. Steenbergen J.N., et al. Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 15245-15250
78. Zhao J., et al. Oxidative stress in plant cell culture: a role in production of β-thujaplicin by Cupressus lusitanica suspension culture. Biotechnol. Bioeng. 90 (2005) 621-631
79. Mahajan-Miklos S., et al. Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts. Mol. Microbiol. 37 (2000) 981-988
80. Jha A.K., et al. Enterococcus faecalis mammalian virulence-related factors exhibit potent pathogenicity in the Arabidopsis thaliana plant model. Infect. Immun. 73 (2005) 464-475