Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro

British Journal of Pharmacology

Volumn 150, Issue 2, 2007, Pages 186-191

  Vandevoorde, S ^a,b   Jonsson, K O ^a   Labar, G ^b   Persson, E ^a   Lambert, D M ^b   Fowler, C J ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

2 acylglycerol; Anandamide; Fatty acid amide hydrolase; Monoacylglycerol lipase; URB597; URB602; URB754

Indexed keywords

(1,1' BIPHENYL) 3 YL CARBAMIC ACID CYCLOHEXYLESTER; 2 OLEOYLGLYCEROL; 6 METHYL 2 [(4 METHYLPHENYL)AMINO] 4H 3,1 BENZOXAZIN 4 ONE; ACYLGLYCEROL LIPASE; ANANDAMIDE; CHLOROFORM; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; ESTERASE INHIBITOR; FATTY ACID AMIDASE; GLYCEROL DERIVATIVE; MESSENGER RNA; METHANOL; METHYLARACHIDONOYL FLUOROPHOSPHONATE; PHOSPHONIC ACID DERIVATIVE; TRITIUM; UNCLASSIFIED DRUG; URB 602; URB 754;

ANIMAL CELL; ARTICLE; BRAIN; BRAIN MEMBRANE; CELL LINE; CHEMICAL LABELING; CONTROLLED STUDY; DRUG SELECTIVITY; ENZYME INHIBITION; EXTRACTION; GENE EXPRESSION; GLIOMA; HOMOGENATE; HYDROLYSIS; IC 50; IN VITRO STUDY; LEUKEMIA CELL; MALE; MAST CELL LEUKEMIA; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT;

AMIDOHYDROLASES; ANILINE COMPOUNDS; ANIMALS; ARACHIDONIC ACIDS; BENZOXAZINES; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CELLS, CULTURED; CEREBELLUM; CYTOSOL; GLYCERIDES; HUMANS; HYDROLYSIS; MALE; MEMBRANES; MICE; MONOACYLGLYCEROL LIPASES; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 33846551684     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706971     Document Type: Article

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