Modeling complex genetic interactions in a simple eukaryotic genome: Actin displays a rich spectrum of complex haploinsufficiencies

Genes and Development

Volumn 21, Issue 2, 2007, Pages 148-159

  Haarer, Brian ^a   Viggiano, Susan ^a   Hibbs, Mathew A ^b   Troyanskaya, Olga G ^b   Amberg, David C ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b Princeton University   (United States)

Author keywords

Actin; Cytoskeleton; Genetic interactions; Haploinsufficiency

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CYTOSKELETON PROTEIN; F ACTIN;

ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; EUKARYOTE; FUNGAL GENE; GENE DELETION; GENE DUPLICATION; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENE MUTATION; GENETIC SCREENING; HEMIZYGOTE; KNOCKOUT GENE; NONHUMAN; NULL ALLELE; PARALOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RIBOSOME SUBUNIT; STOICHIOMETRY; YEAST;

ACTINS; ENDOCYTOSIS; GENE DELETION; GENOME, FUNGAL; HUMANS; MICROFILAMENT PROTEINS; MULTIFACTORIAL INHERITANCE; PHENOTYPE; RIBOSOMES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 33846528944     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1477507     Document Type: Article

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