-
1
-
-
0017250908
-
Non-ketotic diabetes mellitus: Insulin deficiency or insulin resistance?
-
Reaven GM, Bernstein R, Davis B, Olefsky JM: Non-ketotic diabetes mellitus: Insulin deficiency or insulin resistance? Am J Med 60: 80-88, 1976
-
(1976)
Am J Med
, vol.60
, pp. 80-88
-
-
Reaven, G.M.1
Bernstein, R.2
Davis, B.3
Olefsky, J.M.4
-
3
-
-
0028079621
-
Role of human skeletal muscle insulin receptor kinase activity in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity
-
Nolan JJ, Freidenberg G, Henry R, Reichart D, Olefsky JM: Role of human skeletal muscle insulin receptor kinase activity in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity. J Clin Endocrinol Metab 78: 471-477, 1994
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 471-477
-
-
Nolan, J.J.1
Freidenberg, G.2
Henry, R.3
Reichart, D.4
Olefsky, J.M.5
-
4
-
-
0024348996
-
Early metabolic defects in persons at increased risk for noninsulin-dependent diabetes mellitus
-
Eriksson J, Franssila-Kallunki A, Ekstrand A, Saloranta C, Widen E, Schalin C, Groop L: Early metabolic defects in persons at increased risk for noninsulin-dependent diabetes mellitus. N Engl J Med 321: 337-343, 1989
-
(1989)
N Engl J Med
, vol.321
, pp. 337-343
-
-
Eriksson, J.1
Franssila-Kallunki, A.2
Ekstrand, A.3
Saloranta, C.4
Widen, E.5
Schalin, C.6
Groop, L.7
-
5
-
-
0027478788
-
Exercise training and clenbuterol reduce insulin resistance of obese Zucker rats
-
Torgan CE, Brozinick JT Jr, Banks EA, Cortez MY, Wilcox RE, Ivy K: Exercise training and clenbuterol reduce insulin resistance of obese Zucker rats. Am J Physiol 264: E373-E379, 1993
-
(1993)
Am J Physiol
, vol.264
-
-
Torgan, C.E.1
Brozinick J.T., Jr.2
Banks, E.A.3
Cortez, M.Y.4
Wilcox, R.E.5
Ivy, K.6
-
6
-
-
0020065416
-
Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor
-
Kasuga M, Karisson FA, Kahn CR: Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor. Science 215: 185-187, 1982
-
(1982)
Science
, vol.215
, pp. 185-187
-
-
Kasuga, M.1
Karisson, F.A.2
Kahn, C.R.3
-
7
-
-
0020046655
-
Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system
-
Kasuga M, Zick Y, Blithe DL, Crettaz M, Kahn CR: Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system. Nature 298: 667-669, 1982
-
(1982)
Nature
, vol.298
, pp. 667-669
-
-
Kasuga, M.1
Zick, Y.2
Blithe, D.L.3
Crettaz, M.4
Kahn, C.R.5
-
8
-
-
0025837881
-
Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase
-
Rothenberg PL, Land WS, Karasik A, Backer J, White MF, Kahn CR: Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase. J Biol Chem 266: 8302-8311, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 8302-8311
-
-
Rothenberg, P.L.1
Land, W.S.2
Karasik, A.3
Backer, J.4
White, M.F.5
Kahn, C.R.6
-
9
-
-
0022494971
-
Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
-
Ellis L, Clauser E, Morgan DO, Edery M, Roth RA: Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell 45: 721-732, 1986
-
(1986)
Cell
, vol.45
, pp. 721-732
-
-
Ellis, L.1
Clauser, E.2
Morgan, D.O.3
Edery, M.4
Roth, R.A.5
-
10
-
-
0023240110
-
Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus
-
Arner P, Pollare T, Lithell H, Livingston JN: Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 30: 437-440, 1987
-
(1987)
Diabetologia
, vol.30
, pp. 437-440
-
-
Arner, P.1
Pollare, T.2
Lithell, H.3
Livingston, J.N.4
-
11
-
-
0023222361
-
Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes
-
Caro JF, Sinha MK, Raju SM, Ittoo O, Pories M, Flickinger EG, Meelheim D, Dohm GL: Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes. J Clin Invest 79: 1330-1337, 1987
-
(1987)
J Clin Invest
, vol.79
, pp. 1330-1337
-
-
Caro, J.F.1
Sinha, M.K.2
Raju, S.M.3
Ittoo, O.4
Pories, M.5
Flickinger, E.G.6
Meelheim, D.7
Dohm, G.L.8
-
12
-
-
0024321216
-
A defective intramolecullar autoactivation cascade may cause the reduced kinase activity of the skeletal muscle insulin receptor from patients with non-insulin-dependent diabetes mellitus
-
Obermaier-Kusser B, White MF, Pongratz DE, Su Z, Ermel B, Muhlbacher C, Haring HU: A defective intramolecullar autoactivation cascade may cause the reduced kinase activity of the skeletal muscle insulin receptor from patients with non-insulin-dependent diabetes mellitus. J Biol Chem 264: 9497-9504, 1989
-
(1989)
J Biol Chem
, vol.264
, pp. 9497-9504
-
-
Obermaier-Kusser, B.1
White, M.F.2
De Pongratz3
Su, Z.4
Ermel, B.5
Muhlbacher, C.6
Haring, H.U.7
-
13
-
-
0023834406
-
A cascade of tyrosine autophosphorylation in the β-subunit activates the insulin receptor
-
White MF, Shoelson SE, Keutmann H, Kahn CR: A cascade of tyrosine autophosphorylation in the β-subunit activates the insulin receptor. J Biol Chem 263: 2969-2980, 1988
-
(1988)
J Biol Chem
, vol.263
, pp. 2969-2980
-
-
White, M.F.1
Shoelson, S.E.2
Keutmann, H.3
Kahn, C.R.4
-
14
-
-
0141434860
-
Protein kinase C directly phosphorylated the insulin receptor in vitro and reduces its protein-tyrosine kinase activity
-
Bollag GE, Roth RA, Beaudoin J, Mochly-Rosen D, Koskland DE Jr: Protein kinase C directly phosphorylated the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc Natl Acad Sci USA 83: 5822-5824, 1986
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 5822-5824
-
-
Bollag, G.E.1
Roth, R.A.2
Beaudoin, J.3
Mochly-Rosen, D.4
Koskland D.E., Jr.5
-
15
-
-
0023834876
-
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity
-
Takayama S, White MF, Kahn CR: Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity. J Biol Chem 263: 3440-3447, 1988
-
(1988)
J Biol Chem
, vol.263
, pp. 3440-3447
-
-
Takayama, S.1
White, M.F.2
Kahn, C.R.3
-
16
-
-
0022452089
-
Reduced tyrosine kinase activity of insulin receptor isolated from rat adipocyte rendered insulin resistant by catecholamine treatment in vitro
-
Haring HU, Kirsch D, Obermaier B, Ermel B, Machicao F: Reduced tyrosine kinase activity of insulin receptor isolated from rat adipocyte rendered insulin resistant by catecholamine treatment in vitro. Biochem J 234: 59-66, 1996
-
(1996)
Biochem J
, vol.234
, pp. 59-66
-
-
Haring, H.U.1
Kirsch, D.2
Obermaier, B.3
Ermel, B.4
Machicao, F.5
-
17
-
-
0026079536
-
Generation and use of anti-phosphotyrosine antibodies for immunoblotting
-
T. Hunter, B.M. Sefton (eds). Academic Press, San Diego, 1991
-
Kamps MP: (1991) Generation and use of anti-phosphotyrosine antibodies for immunoblotting. In: T. Hunter, B.M. Sefton (eds). Methods in Enzymology. Vol 201, Academic Press, San Diego, 1991, pp 101-110
-
(1991)
Methods in Enzymology
, vol.201
, pp. 101-110
-
-
Kamps, M.P.1
-
18
-
-
0018894634
-
Effect of exercise on synthesis and degradation of muscle protein
-
Dohm GL, Kasperek GJ, Tapscott EB, Beecher GB: Effect of exercise on synthesis and degradation of muscle protein. Biochem J 188: 255-262, 1980
-
(1980)
Biochem J
, vol.188
, pp. 255-262
-
-
Dohm, G.L.1
Kasperek, G.J.2
Tapscott, E.B.3
Beecher, G.B.4
-
19
-
-
0029013231
-
Impaired insulin signaling in skeletal muscle from transgenic mice expressing kinase deficient insulin receptors
-
Chang PY, Goodyear LJ, Benecke H, Markuns JS, Moller DE: Impaired insulin signaling in skeletal muscle from transgenic mice expressing kinase deficient insulin receptors. J Biol Chem 270: 12593-12600, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 12593-12600
-
-
Chang, P.Y.1
Goodyear, L.J.2
Benecke, H.3
Markuns, J.S.4
Moller, D.E.5
-
20
-
-
0027534734
-
Glycemia and exercise training alter glucose transport and GLUT4 in the Zucker rat
-
Sherman WM, Friedman JE, Gao JP, Reed MJ, Elton CW, Dohm GL: Glycemia and exercise training alter glucose transport and GLUT4 in the Zucker rat. Med Sci Sports Exer 25: 341-348, 1993
-
(1993)
Med Sci Sports Exer
, vol.25
, pp. 341-348
-
-
Sherman, W.M.1
Friedman, J.E.2
Gao, J.P.3
Reed, M.J.4
Elton, C.W.5
Dohm, G.L.6
-
21
-
-
0028026320
-
Glucose uptake and GLUT-4 protein distribution in skeletal muscle of the obese Zucker rats
-
Brozinick JT Jr, Etgen GJ Jr, Yaspelkis BB III, Ivy K: Glucose uptake and GLUT-4 protein distribution in skeletal muscle of the obese Zucker rats. Am J Physiol 267: R236-R243, 1994
-
(1994)
Am J Physiol
, vol.267
-
-
Brozinick J.T., Jr.1
Etgen G.J., Jr.2
Yaspelkis B.B. III3
Ivy, K.4
-
22
-
-
0029018196
-
Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects
-
Ahmad F, Considine RV, Goldstein BJ: Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects. J Clin Invest 95: 2806-2812, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 2806-2812
-
-
Ahmad, F.1
Considine, R.V.2
Goldstein, B.J.3
-
23
-
-
0028816605
-
Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR
-
Kulas DT, Zhang WR, Goldstein BJ, Furlanetto RW, Mooney RA: Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR. J Biol Chem 270: 2435-2438, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 2435-2438
-
-
Kulas, D.T.1
Zhang, W.R.2
Goldstein, B.J.3
Furlanetto, R.W.4
Mooney, R.A.5
-
24
-
-
0028023002
-
Serine/ threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling
-
Tanti JF, Gremeaux T, van Obberghen E, Le Marchand-Brustel Y: Serine/ threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. J Biol Chem 269: 6051-6057, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 6051-6057
-
-
Tanti, J.F.1
Gremeaux, T.2
Van Obberghen, E.3
Le Marchand-Brustel, Y.4
-
25
-
-
0030061922
-
1RS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNFαnn obesity-induced insulin resistance
-
Hotamisligil GS, Peraidi P, Budavari A, Ellis R, White MF, Spiegelman BM: 1RS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNFα-and obesity-induced insulin resistance. Science 271: 665-668, 1996
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraidi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
27
-
-
0029119085
-
Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle
-
Dunaif A, Xia J, Book CB, Schenker E, Tang Z: Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. J Clin Invest 96: 801-810, 1995
-
(1995)
J Clin Invest
, vol.96
, pp. 801-810
-
-
Dunaif, A.1
Xia, J.2
Book, C.B.3
Schenker, E.4
Tang, Z.5
-
28
-
-
0021816065
-
Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin
-
Pang DT, Sharma BR, Shafer JA, White MF, Kahn CR: Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin. J Biol Chem 260: 7131-7136, 1985
-
(1985)
J Biol Chem
, vol.260
, pp. 7131-7136
-
-
Pang, D.T.1
Sharma, B.R.2
Shafer, J.A.3
White, M.F.4
Kahn, C.R.5
-
29
-
-
0026347634
-
Dephosphorylation of the insulin receptor partially restores the decreased autophosphorylation in streptozotocin induced diabetic rats
-
Iwama N, Watarai T, Kajimoto Y, Yamasaki Y, Yokoyama T, Kawamori R, Kamada T: Dephosphorylation of the insulin receptor partially restores the decreased autophosphorylation in streptozotocin induced diabetic rats. Diabetes Res 17: 25-32, 1991
-
(1991)
Diabetes Res
, vol.17
, pp. 25-32
-
-
Iwama, N.1
Watarai, T.2
Kajimoto, Y.3
Yamasaki, Y.4
Yokoyama, T.5
Kawamori, R.6
Kamada, T.7
-
30
-
-
0025880943
-
Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor
-
Tavare JM, Zhang B, Ellis L, Roth RA: Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. J Biol Chem 266: 21804-21809, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 21804-21809
-
-
Tavare, J.M.1
Zhang, B.2
Ellis, L.3
Roth, R.A.4
-
31
-
-
0027942711
-
Expression of the major isoenzyme of protein kinase-C in skeletal muscle, PKC theta, varies with muscle type and in response to fructose-induced insulin resistance
-
Donnelly R, Reed MJ, Azhar S, Reaven GM: Expression of the major isoenzyme of protein kinase-C in skeletal muscle, PKC theta, varies with muscle type and in response to fructose-induced insulin resistance. Endocrinology 135: 2369-2374, 1994
-
(1994)
Endocrinology
, vol.135
, pp. 2369-2374
-
-
Donnelly, R.1
Reed, M.J.2
Azhar, S.3
Reaven, G.M.4
-
32
-
-
0030914330
-
Alteration in the expression and cellular localization of protein kinase C isozymes e and 9 are associated with insulin resistance in skeletal muscle of the high-fat-fed rat
-
Schmitz-Peiffer C, Browne CL, Oakes ND, Watkinson A, Chisholm DJ, Kraegen EW, Biden TJ: Alteration in the expression and cellular localization of protein kinase C isozymes e and 9 are associated with insulin resistance in skeletal muscle of the high-fat-fed rat. Diabetes 46: 169-178, 1997
-
(1997)
Diabetes
, vol.46
, pp. 169-178
-
-
Schmitz-Peiffer, C.1
Browne, C.L.2
Oakes, N.D.3
Watkinson, A.4
Chisholm, D.J.5
Kraegen, E.W.6
Biden, T.J.7
-
33
-
-
0029742924
-
Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakiwki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis
-
Avignon A, Yamada K, Zhou X, Spencer B, Cardona O, Saba-Siddique S, Galloway L, Standaert ML, Farese RV: Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakiwki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis. Diabetes 45: 1396-1404, 1996
-
(1996)
Diabetes
, vol.45
, pp. 1396-1404
-
-
Avignon, A.1
Yamada, K.2
Zhou, X.3
Spencer, B.4
Cardona, O.5
Saba-Siddique, S.6
Galloway, L.7
Standaert, M.L.8
Farese, R.V.9
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