The role of neuroimaging in elucidating delirium pathophysiology

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 61, Issue 12, 2006, Pages 1287-1293

  Alsop, David C ^a,c   Fearing, Michael A ^a   Johnson, Keith ^b   Sperling, Reisa ^b   Fong, Tamara G ^a   Inouye, Sharon K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST ENHANCEMENT; DELIRIUM; DEMENTIA; HUMAN; IMAGE ANALYSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; REGULATORY MECHANISM; REVIEW; RISK FACTOR; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 33846451414     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/61.12.1287     Document Type: Review

References (62)

1. Inouye SK. Delirium in older persons. N Engl J Med. 2006;354: 1157-1165.
2. Trzepacz P, van der Mast R. The neuropathology of delirium. In: Lindesay J, Rockwood K, Macdonald A, eds. Delirium in Old Age. Oxford: Oxford University Press; 2002:51-90.
3. Naughton BJ, Moran M, Ghaly Y, Michalakes C. Computed tomography scanning and delirium in elder patients. Acad Emerg Med. 1997;4:1107-1110.
4. Kishi Y, Iwasaki Y, Takezawa K, Kurosawa H, Endo S. Delirium in critical care unit patients admitted through an emergency room. Gen Hosp Psychiatry. 1995;17:371-379.
5. Figiel GS, Krishnan KR, Breitner JC, Nemeroff CB. Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions. J Neuropsychiatry Clin Neurosci. 1989;1: 188-190.
6. Figiel GS, Krishnan KR, Doraiswamy PM. Subcortical structural changes in ECT-induced delirium. J Geriatr Psychiatry Neurol. 1990; 3:172-176.
7. Kobayashi K, Higashima M, Mutou K, et al. Severe delirium due to basal forebrain vascular lesion and efficacy of donepezil. Prog Neuropsychopharmacol Biol Psychiatry. 2004;28:1189-1194.
8. Vatsavayi V, Malhotra S, Franco K. Agitated delirium with posterior cerebral artery infarction. J Emerg Med. 2003;24:263-266.
9. Castellanos-Pinedo F, Galindo R, Adeva-Bartotome MT, Zurdo M. [A relapse of multiple sclerosis manifesting as acute delirium]. Neurologia. 2004;19:323-325.
10. Bogousslavsky J, Ferrazzini M, Regli F, Assal G, Tanabe H, Delaloye-Bischof A. Manic delirium and frontal-like syndrome with paramedian infarction of the right thalamus. J Neurol Neurosurg Psychiatry. 1988; 51:116-119.
11. Ogasawara K, Komoribayashi N. Kobayashi M, et al. Neural damage caused by cerebral hyperperfusion after arterial bypass surgery in a patient with moyamoya disease: case report. Neurosurgery. 2005;56: E1380; discussion E1380.
12. Takanashi J, Barkovich AJ, Shiihara T, et al. Widening spectrum of a reversible splenial lesion with transiently reduced diffusion. AJNR Am J Neuroradiol. 2006;27:836-838.
13. Tada H, Takanashi J, Barkovich AJ, et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology. 2004; 63:1854-1858.
14. Doherty MJ, Jayadev S, Watson NF, Konchada RS, Hallam DK. Clinical implications of splenium magnetic resonance imaging signal changes. Arch Neurol. 2005;62:433-437.
15. Roach RC, Hackett PH. Frontiers of hypoxia research: acute mountain sickness. J Exp Biol. 2001;204:3161-3170.
16. Yokota H, Ogawa S, Kurokawa A, Yamamoto Y. Regional cerebral blood flow in delirium patients. Psychiatry Clin Neurosci. 2003;57: 337-339.
17. Robertsson B, Olsson L, Wallin A. Occurrence of delirium in different regional brain syndromes. Dement Geriatr Cogn Disord. 1999;10: 278-283.
18. Tsukada H, Kakiuchi T, Ando I, Shizuno H, Nakanishi S, Ouchi Y. Regulation of cerebral blood flow response to somatosensory stimulation through the cholinergic system: a positron emission tomography study in unanesthetized monkeys. Brain Res. 1997;749:10-17.
19. Sowell ER, Thompson PM, Toga AW. Mapping changes in the human cortex throughout the span of life. Neuroscientist. 2004;10:372-392.
20. Frisoni GB, Scheltens P, Galluzzi S, et al. Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADC. J Neurol Neurosurg Psychiatry. 2003;74:1371-1381.
21. Wilde EA, Hunter JV, Newsome MR, et al. Frontal and temporal morphometric findings on MRI in children after moderate to severe traumatic brain injury. J Neurotrauma. 2005;22:333-344.
22. Matthews PM, Jezzard P. Functional magnetic resonance imaging. J Neurol Neurosurg Psychiatry. 2004;75:6-12.
23. Dickerson BC, Salat DH, Bates JF, et al. Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol. 2004; 56:27-35.
24. Cooke A, DeVita C, Gee J, et al. Neural basis for sentence comprehension deficits in frontotemporal dementia. Brain Lang. 2003;85: 211-221.
25. Williams DS, Detre JA, Leigh JS, Koretsky AP. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci U S A. 1992;89:212-216.
26. Alsop DC, Detre JA, Grossman M. Assessment of cerebral blood flow in Alzheimer's disease by spin-labeled magnetic resonance imaging. Ann Neurol. 2000;47:93-100.
27. Aguirre GK, Detre JA, Zarahn E, Alsop DC. Experimental design and the relative sensitivity of BOLD and perfusion fMRI. Neuroimage. 2002;15:488-500.
28. Dette JA, Samuels OB, Alsop DC, Gonzalez-At JB, Kasner SE, Raps EC. Noninvasive magnetic resonance imaging evaluation of cerebral blood flow with acetazolamide challenge in patients with cerebrovascular stenosis. J Magn Reson Imaging. 1999;10:870-875.
29. Le Bihan D. Molecular diffusion nuclear magnetic resonance imaging. Magn Reson Q. 1991;7:1-30.
30. Moseley ME, Kucharczyk J, Mintorovitch J, et al. Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am J Neuroradiol. 1990;11:423-429.
31. Le Bihan D. Looking into the functional architecture of the brain with diffusion MRI. Nat Rev Neurosci. 2003;4:469-480.
32. Rose SE, Chen F, Chalk JB, et al. Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging. J Neurol Neurosurg Psychiatry. 2000; 69:528-530.
33. Lim KO, Hedehus M, Moseley M, de Crespigny A, Sullivan EV, Pfefferbaum A. Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging. Arch Gen Psychiatry. 1999;56:367-374.
34. Alexopoulos GS, Kiosses DN, Choi SJ, Murphy CF, Lim KO. Frontal white matter microstructure and treatment response of late-life depression: a preliminary study. Am J Psychiatry. 2002;159:1929-1932.
35. Pavlovsky L, Seiffert E, Heinemann U, Korn A, Golan H, Friedman A. Persistent BBB disruption may underlie alpha interferon-induced seizures. J Neurol. 2005;252:42-46.
36. Su MY, Head E, Brooks WM, et al. Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging. Neurobiol Aging. 1998;19:479-485.
37. Starr JM, Wardlaw J, Ferguson K, MacLullich A, Deary IJ, Marshall I. Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging. J Neurol Neurosurg Psychiatry. 2003;74:70-76.
38. Wang H, Golob EJ, Su MY. Vascular volume and blood-brain barrier permeability measured by dynamic contrast enhanced MRI in hippocampus and cerebellum of patients with MCI and normal controls. J Magn Reson Imaging. 2006;24:695-700.
39. Mathis CA, Bacskai BJ, Kajdasz ST, et al. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorg Med Chem Lett. 2002;12:295-298.
40. Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol. 2004;55:306-319.
41. Fagan AM, Mintun MA, Mach RH, et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Ann Neurol. 2006;59:512-519.
42. Fujita M, Ichise M, Zoghbi SS, et al. Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease. Ann Neurol. 2006; 59:174-177.
43. Brooks DJ. Neuroimaging in Parkinson's disease. NeuroRx. 2004;1: 243-254.
44. Culley DJ, Baxter M, Yukhananov R, Crosby G. The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg. 2003;96:1004-1009, table of contents.
45. Brown DV, Heller F, Barkin R. Anticholinergic syndrome after anesthesia: a case report and review. Am J Ther. 2004;11:144-153.
46. Shih WJ, Hyatt M. Volume and surface three-dimensional displays of Tc-99m HMPAO brain SPECT imaging in a chronic hypnosedative abuser. Clin Nucl Med. 1993;18:506-509.
47. Kohira I, Matsuo E, Shiro Y, et al. Hepatic encephalopathy with increased cerebral blood flow in SPECT and MRI abnormalities in the basal ganglia. Jpn J Psychiatry Neurol. 1994;48:33-36.
48. Doyle M, Warden D. Use of SPECT to evaluate postcardiotomy delirium. Am J Psychiatry. 1996;153:838-839.
49. Ohta H, Matsumoto R, Kato T, Tomono N, Shimizu T. Tc-99m HMPAO brain perfusion SPECT images in a patient with portal-systemic encephalopathy. Clin Nucl Med. 1998;23:634-636.
50. Kamijo Y, Soma K, Kondo R, Ohwada T. Transient diffuse cerebral hypoperfusion in Tc-99m HMPAO SPECT of the brain during withdrawal syndrome following acute barbiturate poisoning. Vet Hum Toxicol. 2002;44:348-350.
51. Pittock SJ, Rabinstein AA, Edwards BS, Wijdicks EF. OKT3 neurotoxicity presenting as akinetic mutism. Transplantation. 2003; 75:1058-1060.
52. Ikeda S, Yazaki M, Takei Y, et al. Type II (adult onset) citrullinaemia: clinical pictures and the therapeutic effect of liver transplantation. J Neurol Neurosurg Psychiatry. 2001;71:663-670.
53. Jalan R, Olde Damink SW, Lui HF, et al. Oral amino acid load mimicking hemoglobin results in reduced regional cerebral perfusion and deterioration in memory tests in patients with cirrhosis of the liver. Metab Brain Dis. 2003;18:37-49.
54. Trzepacz PT, Tarter RE, Shah A, Tringali R, Faett DG, Van Thiel DH. SPECT scan and cognitive findings in subclinical hepatic encephalopathy. J Neuropsychiatry Clin Neurosci. 1994;6:170-175.
55. Strauss GI, Hogh P, Moller K, Knudsen GM, Hansen BA, Larsen FS. Regional cerebral blood flow during mechanical hyperventilation in patients with fulminant hepatic failure. Hepatology. 1999;30:1368-1373.
56. O'Carroll RE, Hayes PC, Ebmeier KP, et al. Regional cerebral blood flow and cognitive function in patients with chronic liver disease. Lancet. 1991;337:1250-1253.
57. Yazgan Y, Narin Y, Demirturk L, et al. Value of regional cerebral blood flow in the evaluation of chronic liver disease and subclinical hepatic encephalopathy. J Gastroenterol Hepatol. 2003;18:1162-1167.
58. Catafau AM, Kulisevsky J, Berna L, et al. Relationship between cerebral perfusion in frontal-limbic-basal ganglia circuits and neuropsychologic impairment in patients with subclinical hepatic encephalopathy. J Nucl Med. 2000;41:405-410.
59. Fong TG, Bogardus ST, Daftary A, et al. Interrelationship Between Delirium and Dementia. Cerebral perfusion changes in older delirious patients using 99mTc HMPAO SPECT. J Gerontol Med Sci. 2006;61A:1294-1299.
60. Ogasawara K, Ogawa A, Okuguchi T, Kobayashi M, Suzuki M, Yoshimoto T. Postoperative hyperperfusion syndrome in elderly patients with chronic subdural hematoma. Surg Neurol. 2000;54:155-159.
61. Gokgoz L, Gunaydin S, Sinci V, et al. Psychiatric, complications of cardiac surgery postoperative delirium syndrome. Scand Cardiovasc J. 1997;31:217-222.
62. Gunaydin B, Babacan A. Cerebral hypoperfusion after cardiac surgery and anesthetic strategies: a comparative study with high dose fentanyl and barbiturate anesthesia. Ann Thorac Cardiovasc Surg. 1998;4:12-17.