메뉴 건너뛰기




Volumn 1, Issue 2, 2004, Pages 243-254

Neuroimaging in Parkinson's Disease

Author keywords

dopamine; neuroprotection; Parkinson's disease; Positron emission tomography; progression; SPECT

Indexed keywords

BIOLOGICAL MARKER;

EID: 23844456320     PISSN: 15455343     EISSN: 15455351     Source Type: Journal    
DOI: 10.1602/neurorx.1.2.243     Document Type: Article
Times cited : (78)

References (94)
  • 1
    • 0035826935 scopus 로고    scopus 로고
    • A comparison of (18)F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson's disease
    • Hu M., White S., Herlihy A., et al. A comparison of (18)F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson's disease. Neurology 56 (2001) 1195-1200
    • (2001) Neurology , vol.56 , pp. 1195-1200
    • Hu, M.1    White, S.2    Herlihy, A.3
  • 2
    • 0034078533 scopus 로고    scopus 로고
    • Structural changes of the substantia nigra in Parkinson's disease as revealed by MR imaging
    • Hutchinson M., and Raff U. Structural changes of the substantia nigra in Parkinson's disease as revealed by MR imaging. AJNR Am J Neuroradiol 21 (2000) 697-701
    • (2000) AJNR Am J Neuroradiol , vol.21 , pp. 697-701
    • Hutchinson, M.1    Raff, U.2
  • 3
    • 0034620601 scopus 로고    scopus 로고
    • Differentiation of atypical parkinsonian syndromes with routine MRI
    • Schrag A., Good C., Miszkiel K., et al. Differentiation of atypical parkinsonian syndromes with routine MRI. Neurology 54 (2000) 697-702
    • (2000) Neurology , vol.54 , pp. 697-702
    • Schrag, A.1    Good, C.2    Miszkiel, K.3
  • 4
    • 0032925853 scopus 로고    scopus 로고
    • Magnetic resonance imaging-based volumetry differentiates idiopathic Parkinson's syndrome from multiple system atrophy and progressive supranuclear palsy
    • Schulz J., Skalej M., Wedekind D., et al. Magnetic resonance imaging-based volumetry differentiates idiopathic Parkinson's syndrome from multiple system atrophy and progressive supranuclear palsy. Ann Neurol 45 (1999) 65-74
    • (1999) Ann Neurol , vol.45 , pp. 65-74
    • Schulz, J.1    Skalej, M.2    Wedekind, D.3
  • 5
    • 0037465774 scopus 로고    scopus 로고
    • Diffusion-weighted imaging discriminates progressive supranuclear palsy from PD, but not from the parkinson variant of multiple system atrophy
    • Seppi K., Schocke M., Esterhammer R., et al. Diffusion-weighted imaging discriminates progressive supranuclear palsy from PD, but not from the parkinson variant of multiple system atrophy. Neurology 60 (2003) 922-927
    • (2003) Neurology , vol.60 , pp. 922-927
    • Seppi, K.1    Schocke, M.2    Esterhammer, R.3
  • 6
    • 0001669030 scopus 로고
    • The pathology of parkinsonism
    • Marsden C., and Fahn S. (Eds), Butterworths, London
    • Jellinger K. The pathology of parkinsonism. In: Marsden C., and Fahn S. (Eds). Movement disorders 2. Ed 1 (1987), Butterworths, London 124-165
    • (1987) Movement disorders 2. Ed 1 , pp. 124-165
    • Jellinger, K.1
  • 7
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: substantia nigra regional selectivity
    • Fearnley J., and Lees A. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114 (1991) 2283-2301
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.1    Lees, A.2
  • 8
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease
    • Kish S., Shannak K., and Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. N Engl J Med 318 (1988) 876-880
    • (1988) N Engl J Med , vol.318 , pp. 876-880
    • Kish, S.1    Shannak, K.2    Hornykiewicz, O.3
  • 9
    • 0037333666 scopus 로고    scopus 로고
    • Staging of brain pathology related to sporadic Parkinson's disease
    • Braak H., Tredici K., Rub U., et al. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24 (2003) 197-211
    • (2003) Neurobiol Aging , vol.24 , pp. 197-211
    • Braak, H.1    Tredici, K.2    Rub, U.3
  • 10
    • 0036202684 scopus 로고    scopus 로고
    • Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease
    • Jellinger K., Seppi K., Wenning G., and Poewe W. Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease. J Neural Transm 109 (2002) 329-339
    • (2002) J Neural Transm , vol.109 , pp. 329-339
    • Jellinger, K.1    Seppi, K.2    Wenning, G.3    Poewe, W.4
  • 11
    • 0006164301 scopus 로고    scopus 로고
    • Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop
    • McKeith I., Galasko D., Kosaka K., et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 47 (1996) 1113-1124
    • (1996) Neurology , vol.47 , pp. 1113-1124
    • McKeith, I.1    Galasko, D.2    Kosaka, K.3
  • 12
    • 0028786098 scopus 로고
    • Clinical and [18F]dopa PET findings in early Parkinson's disease
    • Morrish P., Sawle G., and Brooks D. Clinical and [18F]dopa PET findings in early Parkinson's disease. J Neurol Neurosurg Psychiatry 59 (1995) 597-600
    • (1995) J Neurol Neurosurg Psychiatry , vol.59 , pp. 597-600
    • Morrish, P.1    Sawle, G.2    Brooks, D.3
  • 13
    • 0032870202 scopus 로고    scopus 로고
    • Frontal, striatal, and midbrain dopaminergic function in early and advanced Parkinson's disease: a 3D 18F-dopa PET study
    • Rakshi J., Uema T., Ito K., et al. Frontal, striatal, and midbrain dopaminergic function in early and advanced Parkinson's disease: a 3D 18F-dopa PET study. Brain 122 (1999) 1637-1650
    • (1999) Brain , vol.122 , pp. 1637-1650
    • Rakshi, J.1    Uema, T.2    Ito, K.3
  • 14
    • 0025065388 scopus 로고
    • Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy
    • Brooks D., Ibañez V., Sawle G., et al. Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy. Ann Neurol 28 (1990) 547-555
    • (1990) Ann Neurol , vol.28 , pp. 547-555
    • Brooks, D.1    Ibañez, V.2    Sawle, G.3
  • 15
    • 0025695511 scopus 로고
    • The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease
    • Leenders K., Salmon E., Tyrrell P., et al. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Arch Neurol 47 (1990) 1290-1298
    • (1990) Arch Neurol , vol.47 , pp. 1290-1298
    • Leenders, K.1    Salmon, E.2    Tyrrell, P.3
  • 16
    • 0015745743 scopus 로고
    • Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological, and neurochemical correlations
    • Bernheimer H., Birkmayer W., Hornykiewicz O., et al. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological, and neurochemical correlations. J Neurol Sci 20 (1973) 415-455
    • (1973) J Neurol Sci , vol.20 , pp. 415-455
    • Bernheimer, H.1    Birkmayer, W.2    Hornykiewicz, O.3
  • 17
    • 0018643422 scopus 로고
    • Dopaminergic innervation of the globus pallidus by collaterals from the nigrostriatal pathway
    • Lindvall O., and Bjorklund A. Dopaminergic innervation of the globus pallidus by collaterals from the nigrostriatal pathway. Brain Res 172 (1979) 169-173
    • (1979) Brain Res , vol.172 , pp. 169-173
    • Lindvall, O.1    Bjorklund, A.2
  • 18
    • 0037307956 scopus 로고    scopus 로고
    • Plasticity in the nigropallidal pathway in Parkinson's disease: an 18F-dopa PET study
    • Whone A., Moore R., Piccini P., and Brooks D. Plasticity in the nigropallidal pathway in Parkinson's disease: an 18F-dopa PET study. Ann Neurol 53 (2003) 206-213
    • (2003) Ann Neurol , vol.53 , pp. 206-213
    • Whone, A.1    Moore, R.2    Piccini, P.3    Brooks, D.4
  • 19
    • 0027296568 scopus 로고
    • Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease
    • Frost J., Rosier A., Reich S., et al. Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease. Ann Neurol 34 (1993) 423-431
    • (1993) Ann Neurol , vol.34 , pp. 423-431
    • Frost, J.1    Rosier, A.2    Reich, S.3
  • 20
    • 0032919523 scopus 로고    scopus 로고
    • Striatal uptake of a novel PET ligand, [18F]b-CFT, is reduced in early Parkinson's disease
    • Rinne J., Bergman J., Ruotinnen H., et al. Striatal uptake of a novel PET ligand, [18F]b-CFT, is reduced in early Parkinson's disease. Synapse 31 (1999) 119-124
    • (1999) Synapse , vol.31 , pp. 119-124
    • Rinne, J.1    Bergman, J.2    Ruotinnen, H.3
  • 21
    • 0030610740 scopus 로고    scopus 로고
    • [11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: implications for the symptomatic threshold
    • Guttman M., Burkholder J., Kish S., et al. [11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: implications for the symptomatic threshold. Neurology 48 (1997) 1578-1583
    • (1997) Neurology , vol.48 , pp. 1578-1583
    • Guttman, M.1    Burkholder, J.2    Kish, S.3
  • 22
    • 0029664364 scopus 로고    scopus 로고
    • [I-123] β-CIT SPECT imaging demonstrates bilateral loss of dopamine transporters in hemiparkinsons disease
    • Marek K., Seibyl J., Zoghbi S., et al. [I-123] β-CIT SPECT imaging demonstrates bilateral loss of dopamine transporters in hemiparkinsons disease. Neurology 46 (1996) 231-237
    • (1996) Neurology , vol.46 , pp. 231-237
    • Marek, K.1    Seibyl, J.2    Zoghbi, S.3
  • 23
    • 0033910602 scopus 로고    scopus 로고
    • Correlation of Parkinson's disease severity and duration with I-123-FP-CIT SPECT striatal uptake
    • Benamer H., Patterson J., Wyper D., et al. Correlation of Parkinson's disease severity and duration with I-123-FP-CIT SPECT striatal uptake. Movement Disorders 15 (2000) 692-698
    • (2000) Movement Disorders , vol.15 , pp. 692-698
    • Benamer, H.1    Patterson, J.2    Wyper, D.3
  • 24
    • 0034029152 scopus 로고    scopus 로고
    • Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT imaging: the [123I]-FP-CIT study group
    • Benamer T., Patterson J., Grosset D., et al. Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT imaging: the [123I]-FP-CIT study group. Mov Disord 15 (2000) 503-510
    • (2000) Mov Disord , vol.15 , pp. 503-510
    • Benamer, T.1    Patterson, J.2    Grosset, D.3
  • 25
    • 0035869767 scopus 로고    scopus 로고
    • [C-11, I-127] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites
    • Fischman A., Bonab A., Babich J., et al. [C-11, I-127] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites. Synapse 39 (2001) 332-342
    • (2001) Synapse , vol.39 , pp. 332-342
    • Fischman, A.1    Bonab, A.2    Babich, J.3
  • 26
    • 0033625124 scopus 로고    scopus 로고
    • Binding of [Tc-99m]TRODAT-1 to dopamine transporters in patients with Parkinson's disease and in healthy volunteers
    • Mozley P., Schneider J., Acton P., et al. Binding of [Tc-99m]TRODAT-1 to dopamine transporters in patients with Parkinson's disease and in healthy volunteers. J Nucl Med 41 (2000) 584-589
    • (2000) J Nucl Med , vol.41 , pp. 584-589
    • Mozley, P.1    Schneider, J.2    Acton, P.3
  • 27
    • 1842290405 scopus 로고    scopus 로고
    • Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion?
    • Vingerhoets F., Schulzer M., Caine D., and Snow B. Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion?. Ann Neurol 41 (1997) 58-64
    • (1997) Ann Neurol , vol.41 , pp. 58-64
    • Vingerhoets, F.1    Schulzer, M.2    Caine, D.3    Snow, B.4
  • 28
    • 0029670370 scopus 로고    scopus 로고
    • Differences in the reduced 18F-dopa uptakes of the caudate and the putamen in Parkinson's disease: correlations with the three main symptoms
    • Otsuka M., Ichiya Y., Kuwabara Y., et al. Differences in the reduced 18F-dopa uptakes of the caudate and the putamen in Parkinson's disease: correlations with the three main symptoms. J Neurol Sci 136 (1996) 169-173
    • (1996) J Neurol Sci , vol.136 , pp. 169-173
    • Otsuka, M.1    Ichiya, Y.2    Kuwabara, Y.3
  • 29
    • 0030935431 scopus 로고    scopus 로고
    • Relationship between clinical features of Parkinson's disease and presynaptic dopamine transporter binding assessed with [I-123]IPT and SPECT
    • Tatsch K., Schwarz J., Mozley P., et al. Relationship between clinical features of Parkinson's disease and presynaptic dopamine transporter binding assessed with [I-123]IPT and SPECT. Eur J Nucl Med 24 (1997) 415-421
    • (1997) Eur J Nucl Med , vol.24 , pp. 415-421
    • Tatsch, K.1    Schwarz, J.2    Mozley, P.3
  • 30
    • 18844471416 scopus 로고    scopus 로고
    • In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
    • Lee C., Samii A., Sossi V., et al. In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol 47 (2000) 493-503
    • (2000) Ann Neurol , vol.47 , pp. 493-503
    • Lee, C.1    Samii, A.2    Sossi, V.3
  • 31
    • 0037465371 scopus 로고    scopus 로고
    • Tremor in Parkinson's disease and serotonergic dysfunction: an (11)C-WAY 100635 PET study
    • Doder M., Rabiner E., Turjanski N., et al. Tremor in Parkinson's disease and serotonergic dysfunction: an (11)C-WAY 100635 PET study. Neurology 60 (2003) 601-605
    • (2003) Neurology , vol.60 , pp. 601-605
    • Doder, M.1    Rabiner, E.2    Turjanski, N.3
  • 32
    • 0025244959 scopus 로고
    • The genetics of Parkinson's disease: a reconsideration
    • Golbe L. The genetics of Parkinson's disease: a reconsideration. Neurology 40 Suppl 3 (1990) 7-16
    • (1990) Neurology , vol.40 , Issue.SUPPL. 3 , pp. 7-16
    • Golbe, L.1
  • 33
    • 0031049889 scopus 로고    scopus 로고
    • Dopaminergic function in familial Parkinson's disease: a clinical and 18F-dopa PET study
    • Piccini P., Morrish P., Turjanski N., et al. Dopaminergic function in familial Parkinson's disease: a clinical and 18F-dopa PET study. Ann Neurol 41 (1997) 222-229
    • (1997) Ann Neurol , vol.41 , pp. 222-229
    • Piccini, P.1    Morrish, P.2    Turjanski, N.3
  • 34
    • 0032913951 scopus 로고    scopus 로고
    • The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins
    • Piccini P., Burn D., Ceravalo R., et al. The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins. Ann Neurol 45 (1999) 577-582
    • (1999) Ann Neurol , vol.45 , pp. 577-582
    • Piccini, P.1    Burn, D.2    Ceravalo, R.3
  • 35
    • 0036787533 scopus 로고    scopus 로고
    • Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study
    • Khan N., Brooks D., Pavese N., et al. Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study. Brain 125 (2002) 2248-2256
    • (2002) Brain , vol.125 , pp. 2248-2256
    • Khan, N.1    Brooks, D.2    Pavese, N.3
  • 36
    • 0035096967 scopus 로고    scopus 로고
    • Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene
    • Hilker R., Klein C., Ghaemi M., et al. Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene. Ann Neurol 49 (2001) 367-376
    • (2001) Ann Neurol , vol.49 , pp. 367-376
    • Hilker, R.1    Klein, C.2    Ghaemi, M.3
  • 37
    • 34247190799 scopus 로고    scopus 로고
    • Striatal and extrastriatal PET measurements of dopa metabolism and D2 receptor status in patients with parkin gene mutations
    • Scherfler C., Khan N., Pavese N., et al. Striatal and extrastriatal PET measurements of dopa metabolism and D2 receptor status in patients with parkin gene mutations. Neurology 58 Suppl 3 (2002) A201
    • (2002) Neurology , vol.58 , Issue.SUPPL. 3
    • Scherfler, C.1    Khan, N.2    Pavese, N.3
  • 38
    • 0030916343 scopus 로고    scopus 로고
    • PK ('peripheral benzodiazepine')-binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia
    • Banati R., Myers R., and Kreutzberg G. PK ('peripheral benzodiazepine')-binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia. J Neurocytol 26 (1997) 77-82
    • (1997) J Neurocytol , vol.26 , pp. 77-82
    • Banati, R.1    Myers, R.2    Kreutzberg, G.3
  • 39
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer P., Itagaki S., Boyes B., and McGeer E. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38 (1988) 1285-1291
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.1    Itagaki, S.2    Boyes, B.3    McGeer, E.4
  • 40
    • 0001665918 scopus 로고    scopus 로고
    • In vivo imaging of activated microglia with [C-11]PK11195 positron emission tomography (PET) in idiopathic and atypical Parkinson's disease
    • Gerhard A., Banati R., Cagnin A., and Brooks D. In vivo imaging of activated microglia with [C-11]PK11195 positron emission tomography (PET) in idiopathic and atypical Parkinson's disease. Neurology 56 Suppl 3 (2001) A270
    • (2001) Neurology , vol.56 , Issue.SUPPL. 3
    • Gerhard, A.1    Banati, R.2    Cagnin, A.3    Brooks, D.4
  • 41
    • 0027327049 scopus 로고
    • Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels
    • Snow B., Tooyama I., McGeer E., et al. Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels. Ann Neurol 34 (1993) 324-330
    • (1993) Ann Neurol , vol.34 , pp. 324-330
    • Snow, B.1    Tooyama, I.2    McGeer, E.3
  • 42
    • 0027219169 scopus 로고
    • Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices
    • Pate B., Kawamata T., Yamada T., et al. Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices. Ann Neurol 34 (1993) 331-338
    • (1993) Ann Neurol , vol.34 , pp. 331-338
    • Pate, B.1    Kawamata, T.2    Yamada, T.3
  • 43
    • 0002720085 scopus 로고    scopus 로고
    • Implementation of 3D acquisition, reconstruction, and analysis of dynamic [18F] Fluorodopa studies
    • Myers R., Cunningham V., Bailey D., and Jones T. (Eds), Academic Press, San Diego
    • Rakshi J., Bailey D., Morrish P., and Brooks D. Implementation of 3D acquisition, reconstruction, and analysis of dynamic [18F] Fluorodopa studies. In: Myers R., Cunningham V., Bailey D., and Jones T. (Eds). Quantification of brain function using PET (1996), Academic Press, San Diego 82-87
    • (1996) Quantification of brain function using PET , pp. 82-87
    • Rakshi, J.1    Bailey, D.2    Morrish, P.3    Brooks, D.4
  • 44
    • 0036489157 scopus 로고    scopus 로고
    • 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease
    • Ceravolo R., Piccini P., Bailey D., et al. 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse 43 (2002) 201-207
    • (2002) Synapse , vol.43 , pp. 201-207
    • Ceravolo, R.1    Piccini, P.2    Bailey, D.3
  • 45
    • 0033596829 scopus 로고    scopus 로고
    • Striatal dopaminergic receptor dysfunction in patients with restless legs syndrome: 18F-dopa and 11C-raclopride PET studies
    • Turjanski N., Lees A., and Brooks D. Striatal dopaminergic receptor dysfunction in patients with restless legs syndrome: 18F-dopa and 11C-raclopride PET studies. Neurology 52 (1999) 932-937
    • (1999) Neurology , vol.52 , pp. 932-937
    • Turjanski, N.1    Lees, A.2    Brooks, D.3
  • 46
    • 0033408426 scopus 로고    scopus 로고
    • Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [I-123]β-CIT
    • Innis R., Marek K., Sheff K., et al. Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [I-123]β-CIT. Mov Disord 14 (1999) 436-442
    • (1999) Mov Disord , vol.14 , pp. 436-442
    • Innis, R.1    Marek, K.2    Sheff, K.3
  • 47
    • 0028172598 scopus 로고
    • Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic parkinsonism
    • Vingerhoets F., Snow B., Lee C., et al. Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic parkinsonism. Ann Neurol 36 (1994) 759-764
    • (1994) Ann Neurol , vol.36 , pp. 759-764
    • Vingerhoets, F.1    Snow, B.2    Lee, C.3
  • 48
    • 0031898680 scopus 로고    scopus 로고
    • Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET
    • Morrish P., Rakshi J., Sawle G., and Brooks D. Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET. J Neurol Neurosurg Psychiatry 64 (1998) 314-319
    • (1998) J Neurol Neurosurg Psychiatry , vol.64 , pp. 314-319
    • Morrish, P.1    Rakshi, J.2    Sawle, G.3    Brooks, D.4
  • 49
    • 0035412899 scopus 로고    scopus 로고
    • Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study
    • Nurmi E., Ruottinen H., Bergman J., et al. Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study. Mov Disord 16 (2001) 608-615
    • (2001) Mov Disord , vol.16 , pp. 608-615
    • Nurmi, E.1    Ruottinen, H.2    Bergman, J.3
  • 50
    • 0034041228 scopus 로고    scopus 로고
    • Progression in Parkinson's disease: a positron emission tomography study with a dopamine transporter ligand
    • Nurmi E., Ruottinen H., Kaasinen V., et al. Progression in Parkinson's disease: a positron emission tomography study with a dopamine transporter ligand. Ann Neurol 47 (2000) 804-808
    • (2000) Ann Neurol , vol.47 , pp. 804-808
    • Nurmi, E.1    Ruottinen, H.2    Kaasinen, V.3
  • 51
    • 0035846468 scopus 로고    scopus 로고
    • [123I]β-CIT SPECT imaging assessment of the rate of Parkinson's disease progression
    • Marek K., Innis R., van Dyck C., et al. [123I]β-CIT SPECT imaging assessment of the rate of Parkinson's disease progression. Neurology 57 (2001) 2089-2094
    • (2001) Neurology , vol.57 , pp. 2089-2094
    • Marek, K.1    Innis, R.2    van Dyck, C.3
  • 52
    • 0035225776 scopus 로고    scopus 로고
    • [123I]FP-CIT SPECT is a useful method to monitor the rate of dopaminergic degeneration in early-stage Parkinson's disease
    • Winogrodzka A., Bergmans P., Booij J., et al. [123I]FP-CIT SPECT is a useful method to monitor the rate of dopaminergic degeneration in early-stage Parkinson's disease. J Neural Transm 108 (2001) 1011-1019
    • (2001) J Neural Transm , vol.108 , pp. 1011-1019
    • Winogrodzka, A.1    Bergmans, P.2    Booij, J.3
  • 53
    • 0001064798 scopus 로고    scopus 로고
    • Measuring the decline of dopamine transporter binding in patients with Parkinson's disease using 123I-IPT and SPECT
    • Schwarz J., Tatsch K., Linke R., et al. Measuring the decline of dopamine transporter binding in patients with Parkinson's disease using 123I-IPT and SPECT. Neurology 48 Suppl 2 (1997) A208
    • (1997) Neurology , vol.48 , Issue.SUPPL. 2
    • Schwarz, J.1    Tatsch, K.2    Linke, R.3
  • 54
    • 0031716026 scopus 로고    scopus 로고
    • Dopamine agonists and neuroprotection in Parkinson's disease
    • Olanow C., Jenner P., and Brooks D. Dopamine agonists and neuroprotection in Parkinson's disease. Ann Neurol 44 Suppl1 (1998) S167-S174
    • (1998) Ann Neurol , vol.44 , Issue.Suppl1
    • Olanow, C.1    Jenner, P.2    Brooks, D.3
  • 55
    • 0037785449 scopus 로고    scopus 로고
    • Slower progression of PD with ropinirol versus L-dopa: the REAL-PET study
    • Whone A., Watts R., Stoessl J., et al. Slower progression of PD with ropinirol versus L-dopa: the REAL-PET study. Ann Neurol 54 (2003) 93-101
    • (2003) Ann Neurol , vol.54 , pp. 93-101
    • Whone, A.1    Watts, R.2    Stoessl, J.3
  • 56
    • 0037012478 scopus 로고    scopus 로고
    • Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa Parkinson disease progression
    • Parkinson Study Group. Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa Parkinson disease progression. JAMA 287 (2002) 1653-1661
    • (2002) JAMA , vol.287 , pp. 1653-1661
    • Parkinson Study Group1
  • 57
    • 0037432067 scopus 로고    scopus 로고
    • Slowing Parkinson's disease progression: recent dopamine agonist trials
    • Ahlskog J. Slowing Parkinson's disease progression: recent dopamine agonist trials. Neurology 60 (2003) 381-389
    • (2003) Neurology , vol.60 , pp. 381-389
    • Ahlskog, J.1
  • 58
    • 0027191103 scopus 로고
    • Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors
    • Hadjiconstantinou M., Wemlinger T., Sylvia C., et al. Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors. J Neurochem 60 (1993) 2175-2180
    • (1993) J Neurochem , vol.60 , pp. 2175-2180
    • Hadjiconstantinou, M.1    Wemlinger, T.2    Sylvia, C.3
  • 59
    • 0042372649 scopus 로고    scopus 로고
    • Does levodopa slow or hasten the rate of progression of Parkinson disease? The results of the ELLDOPA trial
    • Parkinson Study Group. Does levodopa slow or hasten the rate of progression of Parkinson disease? The results of the ELLDOPA trial. Neurology 60 Suppl 1 (2003) A80-A81
    • (2003) Neurology , vol.60 , Issue.SUPPL. 1
    • Parkinson Study Group1
  • 60
    • 0033405852 scopus 로고    scopus 로고
    • Cerebral implantation in movement disorders: state of the art
    • Lindvall O. Cerebral implantation in movement disorders: state of the art. Mov Disord 14 (1999) 201-205
    • (1999) Mov Disord , vol.14 , pp. 201-205
    • Lindvall, O.1
  • 61
    • 0033491121 scopus 로고    scopus 로고
    • Dopamine release from nigral transplants visualised in vivo in a Parkinson's patient
    • Piccini P., Brooks D., Bjorklund A., et al. Dopamine release from nigral transplants visualised in vivo in a Parkinson's patient. Nat Neurosci 2 (1999) 1137-1140
    • (1999) Nat Neurosci , vol.2 , pp. 1137-1140
    • Piccini, P.1    Brooks, D.2    Bjorklund, A.3
  • 62
    • 0030834093 scopus 로고    scopus 로고
    • Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
    • Wenning G., Odin P., Morrish P., et al. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Ann Neurol 42 (1997) 95-107
    • (1997) Ann Neurol , vol.42 , pp. 95-107
    • Wenning, G.1    Odin, P.2    Morrish, P.3
  • 63
    • 0033934144 scopus 로고    scopus 로고
    • Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
    • Brundin P., Pogarell O., Hagell P., et al. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain 123 (2000) 1380-1390
    • (2000) Brain , vol.123 , pp. 1380-1390
    • Brundin, P.1    Pogarell, O.2    Hagell, P.3
  • 64
    • 0028991533 scopus 로고
    • Clinical correlates of [18F]fluorodopa uptake in five grafted parkinsonian patients
    • Remy P., Samson Y., Hantraye P., et al. Clinical correlates of [18F]fluorodopa uptake in five grafted parkinsonian patients. Ann Neurol 38 (1995) 580-588
    • (1995) Ann Neurol , vol.38 , pp. 580-588
    • Remy, P.1    Samson, Y.2    Hantraye, P.3
  • 65
    • 0033053030 scopus 로고    scopus 로고
    • Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
    • Hauser R., Freeman T., Snow B., et al. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease. Arch Neurol 56 (1999) 179-187
    • (1999) Arch Neurol , vol.56 , pp. 179-187
    • Hauser, R.1    Freeman, T.2    Snow, B.3
  • 66
    • 0031922226 scopus 로고    scopus 로고
    • Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease
    • Kordower J., Freeman T., Chen E., et al. Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease. Mov Disord 13 (1998) 383-393
    • (1998) Mov Disord , vol.13 , pp. 383-393
    • Kordower, J.1    Freeman, T.2    Chen, E.3
  • 67
    • 0035826089 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • Freed C., Greene P., Breeze R., et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 344 (2001) 710-719
    • (2001) N Engl J Med , vol.344 , pp. 710-719
    • Freed, C.1    Greene, P.2    Breeze, R.3
  • 68
    • 0042837887 scopus 로고    scopus 로고
    • A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
    • Olanow C., Goetz C., Kordower J., et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol 54 (2003) 403-414
    • (2003) Ann Neurol , vol.54 , pp. 403-414
    • Olanow, C.1    Goetz, C.2    Kordower, J.3
  • 69
    • 0038249170 scopus 로고    scopus 로고
    • Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
    • Gill S., Patel N., Hotton G., et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 9 (2003) 589-595
    • (2003) Nat Med , vol.9 , pp. 589-595
    • Gill, S.1    Patel, N.2    Hotton, G.3
  • 70
    • 0033955756 scopus 로고    scopus 로고
    • Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations
    • De La Fuente-Fernandez R., Pal P., Vingerhoets F., et al. Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations. J Neural Transm 107 (2000) 49-57
    • (2000) J Neural Transm , vol.107 , pp. 49-57
    • De La Fuente-Fernandez, R.1    Pal, P.2    Vingerhoets, F.3
  • 71
    • 0026874287 scopus 로고
    • In vivo and in vitro studies of the dopaminergic system in movement disorders
    • Playford E., and Brooks D. In vivo and in vitro studies of the dopaminergic system in movement disorders. Cerebrovasc Brain Metab Rev 4 (1992) 144-171
    • (1992) Cerebrovasc Brain Metab Rev , vol.4 , pp. 144-171
    • Playford, E.1    Brooks, D.2
  • 72
    • 0025274995 scopus 로고
    • Positron emission tomography demonstrates dopamine D2 receptor supersensitivity in the striatum of patients with early Parkinson's disease
    • Rinne U., Laihinen A., Rinne J., et al. Positron emission tomography demonstrates dopamine D2 receptor supersensitivity in the striatum of patients with early Parkinson's disease. Mov Disord 5 (1990) 55-59
    • (1990) Mov Disord , vol.5 , pp. 55-59
    • Rinne, U.1    Laihinen, A.2    Rinne, J.3
  • 73
    • 0028168112 scopus 로고
    • [11C]raclopride and positron emission tomography in previously untreated patients with Parkinson's disease: influence of L-dopa and lisuride therapy on striatal dopamine D2-receptors
    • Antonini A., Schwarz J., Oertel W., et al. [11C]raclopride and positron emission tomography in previously untreated patients with Parkinson's disease: influence of L-dopa and lisuride therapy on striatal dopamine D2-receptors. Neurology 44 (1994) 1325-1329
    • (1994) Neurology , vol.44 , pp. 1325-1329
    • Antonini, A.1    Schwarz, J.2    Oertel, W.3
  • 74
    • 0030827709 scopus 로고    scopus 로고
    • PET studies on striatal dopaminergic receptor binding in drug naive and L-dopa treated Parkinson's disease patients with and without dyskinesia
    • Turjanski N., Lees A., and Brooks D. PET studies on striatal dopaminergic receptor binding in drug naive and L-dopa treated Parkinson's disease patients with and without dyskinesia. Neurology 49 (1997) 717-723
    • (1997) Neurology , vol.49 , pp. 717-723
    • Turjanski, N.1    Lees, A.2    Brooks, D.3
  • 75
    • 0000606169 scopus 로고    scopus 로고
    • Levodopa-induced dyskinesias in idiopathic parkinsonism (IP): a simultaneous PET study of dopamine D1 and D2 receptors
    • Kishore A., De la Fuente-Fernández R., Snow B., et al. Levodopa-induced dyskinesias in idiopathic parkinsonism (IP): a simultaneous PET study of dopamine D1 and D2 receptors. Neurology 48 (1997) A327
    • (1997) Neurology , vol.48
    • Kishore, A.1    De la Fuente-Fernández, R.2    Snow, B.3
  • 76
    • 12644293806 scopus 로고    scopus 로고
    • Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from novel positron emission tomography method
    • Breier A., Su T., Saunders R., et al. Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from novel positron emission tomography method. Proc Natl Acad Sci USA 94 (1997) 2569-2574
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2569-2574
    • Breier, A.1    Su, T.2    Saunders, R.3
  • 77
    • 0031056638 scopus 로고    scopus 로고
    • Differential effects of levodopa on dopaminergic function in early and advanced Parkinson's disease
    • Torstenson R., Hartvig P., Långström B., et al. Differential effects of levodopa on dopaminergic function in early and advanced Parkinson's disease. Ann Neurol 41 (1997) 334-340
    • (1997) Ann Neurol , vol.41 , pp. 334-340
    • Torstenson, R.1    Hartvig, P.2    Långström, B.3
  • 78
    • 0035092779 scopus 로고    scopus 로고
    • Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover
    • De La Fuente-Fernandez R., Lu J., Sossi V., et al. Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover. Ann Neurol 49 (2001) 298-303
    • (2001) Ann Neurol , vol.49 , pp. 298-303
    • De La Fuente-Fernandez, R.1    Lu, J.2    Sossi, V.3
  • 79
    • 0029762313 scopus 로고    scopus 로고
    • Potential of opioid antagonists in the treatment of levodopa-induced dyskinesias in Parkinson's disease
    • Henry B., and Brotchie J. Potential of opioid antagonists in the treatment of levodopa-induced dyskinesias in Parkinson's disease. Drugs Aging 9 (1996) 149-158
    • (1996) Drugs Aging , vol.9 , pp. 149-158
    • Henry, B.1    Brotchie, J.2
  • 80
    • 0028908280 scopus 로고
    • Preproenkephalin and preprotachykinin messenger-RNA expression in normal human basal ganglia and in Parkinson's disease
    • Nisbet A., Foster O., Kingsbury A., et al. Preproenkephalin and preprotachykinin messenger-RNA expression in normal human basal ganglia and in Parkinson's disease. Neuroscience 66 (1995) 361-376
    • (1995) Neuroscience , vol.66 , pp. 361-376
    • Nisbet, A.1    Foster, O.2    Kingsbury, A.3
  • 81
    • 0028984579 scopus 로고
    • L-dopa reverses altered gene expression of substance P but not enkephalin in the caudate-putamen of common marmosets treated with MPTP
    • Jolkkonen J., Jenner P., and Marsden C. L-dopa reverses altered gene expression of substance P but not enkephalin in the caudate-putamen of common marmosets treated with MPTP. Mol Brain Res 32 (1995) 297-307
    • (1995) Mol Brain Res , vol.32 , pp. 297-307
    • Jolkkonen, J.1    Jenner, P.2    Marsden, C.3
  • 82
    • 0025945758 scopus 로고
    • Effects of dopamine denervation on striatal peptide expression in parkinsonian monkeys
    • Lavoie B., Parent A., and Bedard P. Effects of dopamine denervation on striatal peptide expression in parkinsonian monkeys. Can J Neurol Sci 18 (1991) 373-375
    • (1991) Can J Neurol Sci , vol.18 , pp. 373-375
    • Lavoie, B.1    Parent, A.2    Bedard, P.3
  • 83
    • 0030727688 scopus 로고    scopus 로고
    • Opioid receptor binding in Parkinson's patients with and without levodopa-induced dyskinesias
    • Piccini P., Weeks R., and Brooks D. Opioid receptor binding in Parkinson's patients with and without levodopa-induced dyskinesias. Ann Neurol 42 (1997) 720-726
    • (1997) Ann Neurol , vol.42 , pp. 720-726
    • Piccini, P.1    Weeks, R.2    Brooks, D.3
  • 84
    • 34247262201 scopus 로고    scopus 로고
    • Reduced substance P binding in Parkinson's disease complicated by dyskinesias: an F-18-L829165 PET study
    • Whone A., Rabiner E., Arahata Y., et al. Reduced substance P binding in Parkinson's disease complicated by dyskinesias: an F-18-L829165 PET study. Neurology 58 Suppl 3 (2002) A488-A489
    • (2002) Neurology , vol.58 , Issue.SUPPL. 3
    • Whone, A.1    Rabiner, E.2    Arahata, Y.3
  • 85
    • 0034788539 scopus 로고    scopus 로고
    • Dementia in Parkinson's disease
    • Korczyn A. Dementia in Parkinson's disease. J Neurol 248 Suppl 3 (2001) III1-III4
    • (2001) J Neurol , vol.248 , Issue.SUPPL. 3
    • Korczyn, A.1
  • 86
    • 0006258542 scopus 로고
    • Contralateral basal ganglia metabolism is abnormal in hemiparkinsonian patients. An FDG-PET study
    • Miletich R., Chan T., Gillespie M., et al. Contralateral basal ganglia metabolism is abnormal in hemiparkinsonian patients. An FDG-PET study. Neurology 38 (1988) S260
    • (1988) Neurology , vol.38
    • Miletich, R.1    Chan, T.2    Gillespie, M.3
  • 87
    • 0021931775 scopus 로고
    • Alterations of regional cerebral blood flow and oxygen metabolism in Parkinson's disease
    • Wolfson L., Leenders K., Brown L., and Jones T. Alterations of regional cerebral blood flow and oxygen metabolism in Parkinson's disease. Neurology 35 (1985) 1399-1405
    • (1985) Neurology , vol.35 , pp. 1399-1405
    • Wolfson, L.1    Leenders, K.2    Brown, L.3    Jones, T.4
  • 89
    • 0028931484 scopus 로고
    • Assessment of disease severity in Parkinsonism with fluorine-18-fluorodeoxyglucose and PET
    • Eidelberg D., Moeller J., Ishikawa T., et al. Assessment of disease severity in Parkinsonism with fluorine-18-fluorodeoxyglucose and PET. J Nucl Med 36 (1995) 378-383
    • (1995) J Nucl Med , vol.36 , pp. 378-383
    • Eidelberg, D.1    Moeller, J.2    Ishikawa, T.3
  • 90
    • 0006215968 scopus 로고
    • The relationship of cerebral glucose metabolism to cognitive deficits in Parkinson's disease
    • Peppard R., Martin W., Guttman M., et al. The relationship of cerebral glucose metabolism to cognitive deficits in Parkinson's disease. Neurology 38 Suppl 1 (1988) 364
    • (1988) Neurology , vol.38 , Issue.SUPPL. 1 , pp. 364
    • Peppard, R.1    Martin, W.2    Guttman, M.3
  • 91
    • 0000437571 scopus 로고
    • Similarities of cerebral glucose metabolism in Alzheimer's and Parkinsonian dementia
    • Kuhl D., Metter E., and Benson D. Similarities of cerebral glucose metabolism in Alzheimer's and Parkinsonian dementia. J Cereb Blood Flow Metab 5 (1985) S169-S170
    • (1985) J Cereb Blood Flow Metab , vol.5
    • Kuhl, D.1    Metter, E.2    Benson, D.3
  • 92
    • 0033022353 scopus 로고    scopus 로고
    • Motor correlates of occipital glucose hypometabolism in Parkinson's disease without dementia
    • Bohnen N., Minoshima S., Giordani B., et al. Motor correlates of occipital glucose hypometabolism in Parkinson's disease without dementia. Neurology 52 (1999) 541-546
    • (1999) Neurology , vol.52 , pp. 541-546
    • Bohnen, N.1    Minoshima, S.2    Giordani, B.3
  • 93
    • 0033967662 scopus 로고    scopus 로고
    • Cortical dysfunction in non-demented Parkinson's disease patients: a combined (31)P-MRS and (18)FDG-PET study
    • Hu M., Taylor-Robinson S., Chaudhuri K., et al. Cortical dysfunction in non-demented Parkinson's disease patients: a combined (31)P-MRS and (18)FDG-PET study. Brain 123 (2000) 340-352
    • (2000) Brain , vol.123 , pp. 340-352
    • Hu, M.1    Taylor-Robinson, S.2    Chaudhuri, K.3
  • 94
    • 0036321202 scopus 로고    scopus 로고
    • Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand
    • Walker Z., Costa D., Walker R., et al. Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand. J Neurol Neurosurg Psychiatry 73 (2002) 134-140
    • (2002) J Neurol Neurosurg Psychiatry , vol.73 , pp. 134-140
    • Walker, Z.1    Costa, D.2    Walker, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.