-
2
-
-
0032806949
-
Genetic basis of progressive familial intrahepatic cholestasis
-
Jacquemin E, Hadchouel M 1999 Genetic basis of progressive familial intrahepatic cholestasis. J Hepatol 31:377-381
-
(1999)
J Hepatol
, vol.31
, pp. 377-381
-
-
Jacquemin, E.1
Hadchouel, M.2
-
3
-
-
21244440246
-
Progressive familial intrahepatic cholestasis: Genetic disorders of biliary transporters
-
Harris MJ, Le Couteur DG, Arias IM 2005 Progressive familial intrahepatic cholestasis: genetic disorders of biliary transporters. J Gastroenterol Hepatol 20:807-817
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 807-817
-
-
Harris, M.J.1
Le Couteur, D.G.2
Arias, I.M.3
-
4
-
-
0031907132
-
A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis
-
Bull LN, van Eijk MJ, Pawlikowska L, DeYoung JA, Juijn JA, Liao M, Klomp LW, Lomri N, Berger R, Scharschmidt BF, Knisely AS, Houwen RH, Freimer NB 1998 A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis. Nat Genet 18:219-224
-
(1998)
Nat Genet
, vol.18
, pp. 219-224
-
-
Bull, L.N.1
van Eijk, M.J.2
Pawlikowska, L.3
DeYoung, J.A.4
Juijn, J.A.5
Liao, M.6
Klomp, L.W.7
Lomri, N.8
Berger, R.9
Scharschmidt, B.F.10
Knisely, A.S.11
Houwen, R.H.12
Freimer, N.B.13
-
5
-
-
0030869696
-
Identification of a locus for a progressive familial cholestasis PFIC2 on chromosome 2q24
-
Strautnieks SS, Kagalwalla AF, Tanner MS, Knisely AS, Bull L, Freimer N, Kocoshis SA, Gardiner RM, Thompson RJ 1997 Identification of a locus for a progressive familial cholestasis PFIC2 on chromosome 2q24. Am J Hum Genet 61:630-633
-
(1997)
Am J Hum Genet
, vol.61
, pp. 630-633
-
-
Strautnieks, S.S.1
Kagalwalla, A.F.2
Tanner, M.S.3
Knisely, A.S.4
Bull, L.5
Freimer, N.6
Kocoshis, S.A.7
Gardiner, R.M.8
Thompson, R.J.9
-
6
-
-
0040284751
-
Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
-
de Vree JM, Jacquemin E, Sturm E, Cresteil D, Bosma PJ, Aten J, Deleuze JF, Desrochers M, Burdelski M, Bernard O, Oude Elferink RP, Hadchouel M 1998 Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. Proc Natl Acad Sci U S A 95:282-287
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 282-287
-
-
de Vree, J.M.1
Jacquemin, E.2
Sturm, E.3
Cresteil, D.4
Bosma, P.J.5
Aten, J.6
Deleuze, J.F.7
Desrochers, M.8
Burdelski, M.9
Bernard, O.10
Oude Elferink, R.P.11
Hadchouel, M.12
-
7
-
-
0027363563
-
Homozygous disruption of the murine Mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
Smit JJ, Schinkel AH, Oude Elferink RP, Groen AK, Wagenaar E, van Deemter L, Mol CA, Ottenhoff R, van der Lugt, NM van Roon MA 1993 Homozygous disruption of the murine Mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75:451-462
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.1
Schinkel, A.H.2
Oude Elferink, R.P.3
Groen, A.K.4
Wagenaar, E.5
van Deemter, L.6
Mol, C.A.7
Ottenhoff, R.8
van der Lugt, N.M.9
van Roon, M.A.10
-
8
-
-
3242727039
-
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert P, Fuchsbichler A, Wagner M, Zollner G, Kaser A, Tilg H, Krause R, Lammert F, Langner C, Zatloukal K, Marschall HU, Denk H, Trauner M 2004 Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 127:261-274
-
(2004)
Gastroenterology
, vol.127
, pp. 261-274
-
-
Fickert, P.1
Fuchsbichler, A.2
Wagner, M.3
Zollner, G.4
Kaser, A.5
Tilg, H.6
Krause, R.7
Lammert, F.8
Langner, C.9
Zatloukal, K.10
Marschall, H.U.11
Denk, H.12
Trauner, M.13
-
9
-
-
27744512904
-
Mdr2 (Abcb4)-/-mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro-and antifibrogenic genes
-
Popov Y, Patsenker E, Fickert P, Trauner M, Schuppan D 2005 Mdr2 (Abcb4)-/-mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro-and antifibrogenic genes. J Hepatol 43:1045-1054
-
(2005)
J Hepatol
, vol.43
, pp. 1045-1054
-
-
Popov, Y.1
Patsenker, E.2
Fickert, P.3
Trauner, M.4
Schuppan, D.5
-
10
-
-
0035045719
-
The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood
-
Jacquemin E, de Vree JM, Cresteil D, Sokal EM, Sturm E, Dumont M, Scheffer GL, Paul M, Burdelski M, Bosma PJ, Bernard O, Hadchouel M, Elferink RP 2001 The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood. Gastroenterology 120:1448-1458
-
(2001)
Gastroenterology
, vol.120
, pp. 1448-1458
-
-
Jacquemin, E.1
de Vree, J.M.2
Cresteil, D.3
Sokal, E.M.4
Sturm, E.5
Dumont, M.6
Scheffer, G.L.7
Paul, M.8
Burdelski, M.9
Bosma, P.J.10
Bernard, O.11
Hadchouel, M.12
Elferink, R.P.13
-
11
-
-
0030012966
-
Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene
-
van Nieuwkerk CM, Elferink RP, Groen AK, Ottenhoff R, Tytgat GN, Dingemans KP, van den Bergh Weerman MA, Offerhaus GJ 1996 Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene. Gastroenterology 111:165-171
-
(1996)
Gastroenterology
, vol.111
, pp. 165-171
-
-
van Nieuwkerk, C.M.1
Elferink, R.P.2
Groen, A.K.3
Ottenhoff, R.4
Tytgat, G.N.5
Dingemans, K.P.6
van den Bergh Weerman, M.A.7
Offerhaus, G.J.8
-
12
-
-
0031049399
-
Ursodeoxycholic acid therapy in pediatric patients with progressive familial intrahepatic cholestasis
-
Jacquemin E, Hermans D, Myara A, Habes D, Debray D, Hadchouel M, Sokal EM, Bernard O 1997 Ursodeoxycholic acid therapy in pediatric patients with progressive familial intrahepatic cholestasis. Hepatology 25:519-523
-
(1997)
Hepatology
, vol.25
, pp. 519-523
-
-
Jacquemin, E.1
Hermans, D.2
Myara, A.3
Habes, D.4
Debray, D.5
Hadchouel, M.6
Sokal, E.M.7
Bernard, O.8
-
13
-
-
0031692632
-
The role of dietary choline in the beneficial effects of lecithin on the secretion of biliary lipids in rats
-
LeBlanc MJ, Gavino V, Perea A, Yousef IM, Levy E, Tuchweber B 1998 The role of dietary choline in the beneficial effects of lecithin on the secretion of biliary lipids in rats. Biochim Biophys Acta 1393:223-234
-
(1998)
Biochim Biophys Acta
, vol.1393
, pp. 223-234
-
-
LeBlanc, M.J.1
Gavino, V.2
Perea, A.3
Yousef, I.M.4
Levy, E.5
Tuchweber, B.6
-
14
-
-
0037256505
-
Effects of dietary soybean lecithin on plasma lipid transport and hepatic cholesterol metabolism in rats
-
LeBlanc MJ, Brunet S, Bouchard G, Lamireau T, Yousef IM, Gavino V, Levy E, Tuchweber B 2003 Effects of dietary soybean lecithin on plasma lipid transport and hepatic cholesterol metabolism in rats. J Nutr Biochem 14:40-48
-
(2003)
J Nutr Biochem
, vol.14
, pp. 40-48
-
-
LeBlanc, M.J.1
Brunet, S.2
Bouchard, G.3
Lamireau, T.4
Yousef, I.M.5
Gavino, V.6
Levy, E.7
Tuchweber, B.8
-
15
-
-
0030767712
-
Polyenylphosphatidylcholine prevents carbon tetrachloride-induced lipid peroxidation while it attenuates liver fibrosis
-
Aleynik SI, Leo MA, Ma X, Aleynik MK, Lieber CS 1997 Polyenylphosphatidylcholine prevents carbon tetrachloride-induced lipid peroxidation while it attenuates liver fibrosis. J Hepatol 27:554-561
-
(1997)
J Hepatol
, vol.27
, pp. 554-561
-
-
Aleynik, S.I.1
Leo, M.A.2
Ma, X.3
Aleynik, M.K.4
Lieber, C.S.5
-
16
-
-
0028088898
-
Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon
-
Lieber CS, Robins SJ, Li J, DeCarli LM, Mak KM, Fasulo JM, Leo MA 1994 Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon. Gastroenterology 106:152-159
-
(1994)
Gastroenterology
, vol.106
, pp. 152-159
-
-
Lieber, C.S.1
Robins, S.J.2
Li, J.3
DeCarli, L.M.4
Mak, K.M.5
Fasulo, J.M.6
Leo, M.A.7
-
17
-
-
0020315758
-
Light microscopic distinction of collagens in hepatic cirrhosis
-
Waldrop FS, Puchtler H 1982 Light microscopic distinction of collagens in hepatic cirrhosis. Histochemistry 74:487-491
-
(1982)
Histochemistry
, vol.74
, pp. 487-491
-
-
Waldrop, F.S.1
Puchtler, H.2
-
18
-
-
0018178473
-
Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile
-
Turley SD, Dietschy JM 1978 Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile. J Lipid Res 19:924-928
-
(1978)
J Lipid Res
, vol.19
, pp. 924-928
-
-
Turley, S.D.1
Dietschy, J.M.2
-
19
-
-
0027933164
-
Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis. Evaluation in rats by combined radiochromatography and gas-liquid chromatography-mass spectrometry
-
Dionne S, Tuchweber B, Plaa GL, Yousef IM 1994 Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis. Evaluation in rats by combined radiochromatography and gas-liquid chromatography-mass spectrometry. Biochem Pharmacol 48:1187-1197
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1187-1197
-
-
Dionne, S.1
Tuchweber, B.2
Plaa, G.L.3
Yousef, I.M.4
-
20
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG, Dyer WJ 1959 A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
22
-
-
0025247125
-
Hepatic injury induced by bile salts: Correlation between biochemical and morphological events
-
Schmucker DL, Ohta M, Kanai S, Sato Y, Kitani K 1990 Hepatic injury induced by bile salts: correlation between biochemical and morphological events. Hepatology 12:1216-1221
-
(1990)
Hepatology
, vol.12
, pp. 1216-1221
-
-
Schmucker, D.L.1
Ohta, M.2
Kanai, S.3
Sato, Y.4
Kitani, K.5
-
23
-
-
0026636390
-
Comparative hepatotoxicity of cholic acid, deoxycholic acid and lithocholic acid in the rat: In vivo and in vitro studies
-
Delzenne NM, Calderon PB, Taper HS, Roberfroid MB 1992 Comparative hepatotoxicity of cholic acid, deoxycholic acid and lithocholic acid in the rat: in vivo and in vitro studies. Toxicol Lett 61:291-304
-
(1992)
Toxicol Lett
, vol.61
, pp. 291-304
-
-
Delzenne, N.M.1
Calderon, P.B.2
Taper, H.S.3
Roberfroid, M.B.4
-
24
-
-
0032919402
-
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
-
Faubion WA, Guicciardi ME, Miyoshi H, Bronk SF, Roberts PJ, Svingen PA, Kaufman SH, Gores GJ 1999 Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest 103:137-145
-
(1999)
J Clin Invest
, vol.103
, pp. 137-145
-
-
Faubion, W.A.1
Guicciardi, M.E.2
Miyoshi, H.3
Bronk, S.F.4
Roberts, P.J.5
Svingen, P.A.6
Kaufman, S.H.7
Gores, G.J.8
-
25
-
-
0032899948
-
Bile acid feeding induces cholangiocyte proliferation and secretion: Evidence for bile acid-regulated ductal secretion
-
Alpini G, Glaser SS, Ueno Y, Rodgers R, Phinizy JL, Francis H, Baiochi L, Holcomb LA, Caligiuri A, Le Sage GD 1999 Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion. Gastroenterology 116:179-186
-
(1999)
Gastroenterology
, vol.116
, pp. 179-186
-
-
Alpini, G.1
Glaser, S.S.2
Ueno, Y.3
Rodgers, R.4
Phinizy, J.L.5
Francis, H.6
Baiochi, L.7
Holcomb, L.A.8
Caligiuri, A.9
Le Sage, G.D.10
-
26
-
-
0037422983
-
Effects of bile acids on biliary epithelial cells: Proliferation, cytotoxicity, and cytokine secretion
-
Lamireau T, Zoltowska M, Levy E, Yousef I, Rosenbaum J, Tuchweber B, Desmouliere A 2003 Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. Life Sci 72:1401-1411
-
(2003)
Life Sci
, vol.72
, pp. 1401-1411
-
-
Lamireau, T.1
Zoltowska, M.2
Levy, E.3
Yousef, I.4
Rosenbaum, J.5
Tuchweber, B.6
Desmouliere, A.7
-
27
-
-
0032602367
-
Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E
-
Marra F, DeFranco R, Grappone C, Parola M, Milani S, Leonarduzzi G, Pastacaldi S, Wenzel UO, Pinzani M, Dianzani MU, Laffi G, Gentilini P 1999 Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E. J Investig Med 47:66-75
-
(1999)
J Investig Med
, vol.47
, pp. 66-75
-
-
Marra, F.1
DeFranco, R.2
Grappone, C.3
Parola, M.4
Milani, S.5
Leonarduzzi, G.6
Pastacaldi, S.7
Wenzel, U.O.8
Pinzani, M.9
Dianzani, M.U.10
Laffi, G.11
Gentilini, P.12
-
28
-
-
0028244643
-
IL-6 induces hepatic inflammation and collagen synthesis in vivo
-
Choi I, Kang HS, Yang Y, Pyun KH 1994 IL-6 induces hepatic inflammation and collagen synthesis in vivo. Clin Exp Immunol 95:530-535
-
(1994)
Clin Exp Immunol
, vol.95
, pp. 530-535
-
-
Choi, I.1
Kang, H.S.2
Yang, Y.3
Pyun, K.H.4
-
29
-
-
0030014283
-
Polyenylphosphatidylcholine attenuates non-alcoholic hepatic fibrosis and accelerates its regression
-
Ma X, Zhao J, Lieber CS 1996 Polyenylphosphatidylcholine attenuates non-alcoholic hepatic fibrosis and accelerates its regression. J Hepatol 24:604-613
-
(1996)
J Hepatol
, vol.24
, pp. 604-613
-
-
Ma, X.1
Zhao, J.2
Lieber, C.S.3
-
30
-
-
0030032905
-
Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat
-
Tuchweber B, Desmouliere A, Bochaton-Piallat ML, Rubbia-Brandt L, Gabbiani G 1996 Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat. Lab Invest 74:265-278
-
(1996)
Lab Invest
, vol.74
, pp. 265-278
-
-
Tuchweber, B.1
Desmouliere, A.2
Bochaton-Piallat, M.L.3
Rubbia-Brandt, L.4
Gabbiani, G.5
-
31
-
-
0033117629
-
Dilinoleoylphosphatidylcholine decreases hepatic stellate cell activation
-
Poniachik J, Baraona E, Zhao J, Lieber CS 1999 Dilinoleoylphosphatidylcholine decreases hepatic stellate cell activation. J Lab Clin Med 133:342-348
-
(1999)
J Lab Clin Med
, vol.133
, pp. 342-348
-
-
Poniachik, J.1
Baraona, E.2
Zhao, J.3
Lieber, C.S.4
-
32
-
-
0036840372
-
DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells
-
Cao Q, Mak KM, Lieber CS 2002 DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 283:G1051-G1061
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Cao, Q.1
Mak, K.M.2
Lieber, C.S.3
-
33
-
-
0026544698
-
Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes
-
Li J, Kim CI, Leo MA, Mak KM, Rojkind M, Lieber CS 1992 Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes. Hepatology 15:373-381
-
(1992)
Hepatology
, vol.15
, pp. 373-381
-
-
Li, J.1
Kim, C.I.2
Leo, M.A.3
Mak, K.M.4
Rojkind, M.5
Lieber, C.S.6
-
34
-
-
0026670128
-
Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis
-
Parola M, Leonarduzzi G, Biasi F, Albano E, Biocca ME, Poli G, Dianzani MU 1992 Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis. Hepatology 16:1014-1021
-
(1992)
Hepatology
, vol.16
, pp. 1014-1021
-
-
Parola, M.1
Leonarduzzi, G.2
Biasi, F.3
Albano, E.4
Biocca, M.E.5
Poli, G.6
Dianzani, M.U.7
-
35
-
-
0028838193
-
Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression
-
Lee KS, Buck M, Houglum K, Chojkier M 1995 Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest 96:2461-2468
-
(1995)
J Clin Invest
, vol.96
, pp. 2461-2468
-
-
Lee, K.S.1
Buck, M.2
Houglum, K.3
Chojkier, M.4
-
36
-
-
0030977808
-
Polyenylphosphatidylcholine decreases alcohol-induced oxidative stress in the baboon
-
Lieber CS, Leo MA, Aleynik SI, Aleynik MK, DeCarli LM 1997 Polyenylphosphatidylcholine decreases alcohol-induced oxidative stress in the baboon. Alcohol Clin Exp Res 21:375-379
-
(1997)
Alcohol Clin Exp Res
, vol.21
, pp. 375-379
-
-
Lieber, C.S.1
Leo, M.A.2
Aleynik, S.I.3
Aleynik, M.K.4
DeCarli, L.M.5
-
37
-
-
0027202006
-
Inhibition of non-enzymatic lipid peroxidation by 'Essentiale' a drug enriched in phosphatidylcholine in ethanol-induced liver injury
-
Chwiecko M, Holownia A, Bielawska A, Farbiszewski R 1993 Inhibition of non-enzymatic lipid peroxidation by 'Essentiale' a drug enriched in phosphatidylcholine in ethanol-induced liver injury. Drug Alcohol Depend 33:87-93
-
(1993)
Drug Alcohol Depend
, vol.33
, pp. 87-93
-
-
Chwiecko, M.1
Holownia, A.2
Bielawska, A.3
Farbiszewski, R.4
-
38
-
-
0034092622
-
Attenuation of alcohol-induced apoptosis of hepatocytes in rat livers by polyenylphosphatidylcholine (PPC)
-
Mi LJ, Mak KM, Lieber CS 2000 Attenuation of alcohol-induced apoptosis of hepatocytes in rat livers by polyenylphosphatidylcholine (PPC). Alcohol Clin Exp Res 24:207-212
-
(2000)
Alcohol Clin Exp Res
, vol.24
, pp. 207-212
-
-
Mi, L.J.1
Mak, K.M.2
Lieber, C.S.3
-
39
-
-
0347694785
-
Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes
-
Komichi D, Tazuma S, Nishioka T, Hyogo H, Une M, Chayama K 2003 Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes. Dig Dis Sci 48:2315-2322
-
(2003)
Dig Dis Sci
, vol.48
, pp. 2315-2322
-
-
Komichi, D.1
Tazuma, S.2
Nishioka, T.3
Hyogo, H.4
Une, M.5
Chayama, K.6
|