Quantification of PET studies with the very high-affinity dopamine D 2/D3 receptor ligand [11C]FLB 457: Re-evaluation of the validity of using a cerebellar reference region

Journal of Cerebral Blood Flow and Metabolism

Volumn 27, Issue 2, 2007, Pages 378-392

  Asselin, Marie Claude ^a,b   Montgomery, Andrew J ^a   Grasby, Paul M ^a   Hume, Susan P ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

11C FLB 457; Cerebellar reference region; Dopamine D 2 D3 receptors; Extrastriatal tissues; Positron emission tomography (PET)

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; ISOREMOXIPRIDE; ISOREMOXIPRIDE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; CEREBELLUM; CONTROLLED STUDY; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG STABILITY; DRUG UPTAKE; EX VIVO STUDY; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RAT; RECEPTOR AFFINITY; THALAMUS; VALIDATION PROCESS;

ADULT; ALGORITHMS; ANIMALS; AREA UNDER CURVE; CARBON RADIOISOTOPES; CEREBELLUM; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DOPAMINE ANTAGONISTS; HUMANS; LIGANDS; MALE; MEMBRANE POTENTIALS; POSITRON-EMISSION TOMOGRAPHY; PYRROLIDINES; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; REPRODUCIBILITY OF RESULTS; SALICYLAMIDES;

EID: 33846427725     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600340     Document Type: Article

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