Alkaloids of the Hernandiaceae: Occurrence and a Compilation of their Biological Activities

Alkaloids: Chemistry and Biology

Volumn 62, Issue , 2005, Pages 175-243

  Conserva, Lucia M ^a   Pereira, Cynara de Araújo B ^a   Barbosa Filho, José Maria ^b  

^a FEDERAL UNIVERSITY OF ALAGOAS   (Brazil)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID;

ANGIOSPERM; CHEMISTRY; ISOLATION AND PURIFICATION; REVIEW; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANGIOSPERMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846414702     PISSN: 10994831     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1099-4831(05)62003-2     Document Type: Review

References (275)

1. Dahlgren R.M.T. Bot. J. Linn. Soc. 80 (1980) 91
2. L. Watson and M. J. Dallwiitz, "The Families of Flowering Plants" http://biodiversity. uno.edu./delta. Accessed in 07 of June (2002)
3. Chalandre M.C., Bruneton J., Cabalion P., and Guinaudeau H. J. Nat. Prod. 49 (1986) 101
4. A. B. Joly, "Botânica: Introdução a Taxonomia Vegetal", p. 296. Ed. Nacional, São Paulo, 1998
5. Singh Y.N., Ikahihifo T., Panuve M., and Slatter C. J. Ethnopharmacol. 12 (1984) 305
6. Arnold H.J., and Gulumian M. J. Ethnopharmacol. 12 (1984) 35
7. Udino L., Abaul J., Bourgeois P., Gorrichon L., Duran H., and Zedde C. Planta Med. 65 (1999) 279
8. Rasoanaivo P., Ratsimamanga-Urverg S., Galeffi C., Nicoletti M., Frapier F., and Martin M.T. Tetrahedron 51 (1995) 1221
9. Rasoanaivo P., Ratsimamanga-Urverg S., Rafatro H., Ramanitrahasimbola D., Palazzino G., Galeffi C., and Nicoletti M. Planta Med. 64 (1998) 58
10. D. Vitallyos, "Phytotherapy in Domestic Traditional Medicine in Matouba-Papaye (Guadaloupe)". Ph.D. Thesis, Univ. Paris, 1979
11. Chalandre M.C., Jacquemin H., and Bruneton J. J. Nat. Prod. 48 (1985) 333
12. Munoz V., Sauvain M., Mollinedo P., Callapa J., Rojas I., Gimenez A., Valentin A., and Mallie M. Planta Med. 65 (1999) 448
13. Chen J.J., Chang Y.L., Teng C.M., and Chen I.S. Planta Med. 66 (2000) 251
14. Chen K.S., Wu Y.C., Ten C.M., Ko J.N., and Wu T.S. J. Nat. Prod. 60 (1997) 645
15. Ross S.A., Minard R.D., Shamma M., Fagbule M.O., Olatunji G., and Gbile Z. J. Nat. Prod. 48 (1985) 835
16. Gu J.Q., Park E.J., Totura S., Riswan S., Fong H.H.S., Pezzuto J.M., and Kinghorn A.D. J. Nat. Prod. 65 (2002) 1065
17. Richomme P., and Bruneton J. J. Nat. Prod. 47 (1984) 879
18. Richomme P., Lavault M., Jacquemin H., and Bruneton J. Planta Med. 50 (1984) 20
19. De Almeida R.N., Barbosa-Filho J.M., Rumjanek V.M., and Braz-Filho R. J. Braz. Chem. Soc. 2 (1991) 71
20. Gottlieb O.R., Guimarães I.S.D.E.S., Magalhães M.T., Mesquita A.A.L., and De Oliveira W.G. Acta Amazonica 10 (1980) 425
21. Yakushijin K., Skibayama K., Murata H., and Furukawa H. Heterocycles 14 (1980) 397
22. Chen J.J., Chang Y.L., Teng C.M., and Chen I.S. Planta Med. 67 (2001) 593
23. Ito C., Matsui T., Wu T.S., and Furukawa H. Chem. Pharm. Bull 40 (1992) 1318
24. Ito C., Itogawa M., Ogata M., Mou X.Y., Tokuda H., Nishino H., and Furukawa H. Planta Med. 67 (2001) 166
25. Chen J.J., Ishikawa T., Duh C.Y., Tsai I.L., and Chen I.S. Planta Med. 62 (1996) 528
26. Chen I.S., Chen J.J., Duh C.Y., Tsai I.L., and Chang C.T. Planta Med. 63 (1997) 154
27. Pernet P.R. Planta Med. 20 (1971) 314
28. J. M. Barbosa-Filho, E. V. Leitão da Cunha, and A. I. Gray, in "The Alkaloids", vol. 54, p. 1. Academic Press, San Diego, 2000
29. Leitão G.G., Simas N.K., Soares S.S.V., De Brito A.P.P., Claros B.M.G., Brito T.B.M., and Delle Monache F. J. Ethnopharmacol. 65 (1999) 87
30. Zhang G.C.F., Nakamura N., Tewtrakul S., Hattori M., Sun Q., Wang Z.T., and Fujiwara T. Chem. Pharm. Bull. 50 (2002) 1195
31. Bruneton J., Shamma M., Minard R.D., Freyer A.J., and Guinaudeau H. J. Org. Chem. 48 (1983) 3957
32. Chen I.S., Chen J.J., Tsai I.L., Chang Y.L., and Teng C.M. Planta Med. 61 (1995) 537
33. Duté P., Chalandre M.C., Cabalion P., and Bruneton J. Phytochemistry 27 (1988) 655
34. Chen J.J., Tsai I.L., Ishikawa T., Wang C.J., and Chen I.S. Phytochemistry 42 (1996) 1479
35. Yang T.H., Liu S.C., and Lin T.S. J. Chin. Chem. Soc. 24 (1977) 91
36. Y. P. Chen, Proc. Int. Symp. Recent Adv. Nat. Prod. Res., Seoul-Korea, Dec. 14-16, 18-23 (1979)
37. Hahn R.A., Nelson J.W., Tye A., and Beal J.L. J. Pharm. Sci. 55 (1966) 466
38. Milushev A., and Damyanova M. Probl. Onkol. 11 (1983) 40
39. Maleev A., Stoichkov J., Todorov D., Mikhaleva K., Mollov N.M., and Duchevska K. Dokl. Bolg. Akad. Nauk. 28 (1975) 713
40. Mircheva I., and Stoichkov I. Probl. Onkol. (1977) 17
41. Stoychkov J., and Miloushev A. Biomed. Express 33 (1980) 42
42. Kuroda H., Nakazawa S., Katagiri K., Shiratori O., Kozuka M., Fujitani K., and Tomita M. Chem. Pharm. Bull. 24 (1976) 2413
43. Perdue Jr. R.E. J. Nat. Prod. 45 (1982) 418
44. Todorov D.K., and Zeller W.J. Cancer J. Res. Clin. Oncol. 118 (1992) 83
45. Kupchan S.M., Chakravarti K.K., and Yokoyama N. J. Pharm. Sci. 52 (1963) 985
46. M. C. Chalandre, P. Cabalion, H. Guinaudeau, and J. Bruneton, Abstr. Internat. Res. Cong. Nat. Prod. Coll. Pharm. Univ. N. Carolina Chapel Hill, NC, July 7-12, Abstr-140A (1985)
47. Chalandre M.C., Bruneton J., Cabalion P., and Guinaudeau H. Can. J. Chem. 64 (1986) 123
48. Ratsimamanga-Urverg S., Rasoanaivo P., Rafatro H., Robijaona B., and Rakoto-Ratsimamanga A. Ann. Trop. Med. Parasitol. 88 (1994) 271
49. Menachery M.D., Lavanier G.L., Wetherley M.L., Guinaudeau H., and Shamma M. J. Nat. Prod. 49 (1986) 745
50. Castedo L., and Tojo G. In: Brossi A. (Ed). The Alkaloids 39 (1992), Academic Press, San Diego 99
51. Dittmar A. J. Ethnopharmacol. 33 (1991) 243
52. Sepulveda-Boza S., and Cassels B.K. Planta Med. 62 (1996) 98
53. Yuan A.X., Qin L., and Kang S.H. Chih Wu Hsueh Pao 29 (1987) 324
54. Lavault M., Debray M.M., and Bruneton J. Bull. Mus. Natl. Hist. Nat. Sect. B 2 (1980) 387
55. Zhou T., and Chen A.L. Chung Ts`Ao Yao 22 (1991) 393
56. Chalandre M.C., Guinaudeau H., and Bruneton J. C. R. Acad. Sci. Ser. II 31 (1985) 1185
57. Chen I.S., Chen J.J., and Tsai I.L. Phytochemistry 40 (1995) 983
58. Cava M.P., Bessho K., Douglas B., Markey S., and Weisbach J.A. Tetrahedron Lett. 36 (1966) 4279
59. Cava M.P., and Venkateswarlu A. Tetrahedron 27 (1971) 2639
60. Yakushijin K., Sugiyama S., Mori Y., Murata H., and Furukawa H. Phytochemistry 19 (1980) 161
61. Yang T.H., Liu S.C., Lin T.S., and Yang L.M. J. Chin. Chem. Soc. 23 (1976) 29
62. Chen J.J., Tsai I.L., and Chen I.S. J. Nat. Prod. 59 (1996) 156
63. Chen I.S., Chen J.J., and Tsai I.L. Heterocycles 43 (1996) 799
64. Chalandre M.C., Pareyre C., and Bruneton J. Ann. Pharm. Fr. 42 (1984) 317
65. Lavault M., Debray M.M., and Bruneton J. Planta Med. 42 (1981) 50
66. Bruneton J. C. R. Acad. Sci. Ser. C 291 (1980) 187
67. Lavault M., Cabalion P., and Bruneton J. Planta Med. 46 (1982) 119
68. th, 49-53 (1985)
69. Soh K.S., Lahey F.N., and Greenhalgh R. Tetrahedron Letters 43 (1966) 5279
70. Cava M.P., Bessho K., Douglas B., Markey S., Raffauf R.F., and Weisbach J.A. Tetrahedron Lett. 15 (1966) 1577
71. Lahey F.N., and MarK K.F. Aust. J. Chem. 24 (1971) 671
72. Ito K., and Furukawa H. Tetrahedron Lett. 34 (1970) 3023
73. Liu S.L. J. Chin. Chem. Soc. 24 (1977) 209
74. J. J. Willaman and B. G. Schubert, Ars, USDA, Tech Bull 1234, Supt Documents, Govt Print Office, Washington, DC (1961)
75. Krane B.D., and Shamma M. J. Nat. Prod. 45 (1982) 377
76. Hong G.X., Teng Z., Qin W.C., and Wei B.W. Yao Hsueh Hsueh Pao 23 (1988) 779
77. Montanha J.A., Amoros M., Boustie J., and Girre L. Planta Med. 61 (1995) 419
78. Boustie J., Stigliani J.L., Momtanha J., Amoros M., Payard M., and Girre L. J. Nat. Prod. 61 (1998) 480
79. Stevigny C., Block S., De Pawu-Gillet M.C., Hoffmann E., Llabres G., Adjakidje V., and Quetin-Leclercq J. Planta Med. 68 (2002) 1042
80. Chang F.R., Chao Y.C., Teng C.M., and Wu Y.C. J. Nat. Prod. 61 (1998) 863
81. Wu Y.C., Chang F.R., Chao Y.C., and Teng C.M. Phytother. Res. Suppl. 12 (1998) 39
82. Chen K.S., Ko F.N., Teng C.M., and Wu Y.C. Planta Med. 62 (1996) 133
83. Wang B.H., Lu Z.X., and Polya G.M. Planta Med. 63 (1997) 494
84. Gupta S., and Bhakuni D.S. Planta Med. 55 (1989) 197
85. Bohlke M., Guinaudeau H., Angerhofer C.K., Wongpanich V., Soejarto D.D., Farnsworth N.R., Mora G.A., and Poveda L.J. J. Nat. Prod. 59 (1996) 576
86. Geonya N.I., and Progressov M.M. ZH Mikrobiol Akad Nauk UKR RSR 23 (1961) 24
87. Zetler G. Arch. Int. Pharmacodyn. Ther. 296 (1988) 255
88. Mitscher L.A., Leu R.P., Bathala M.S., Wu W., and Beal J.L. Lloydia 35 (1972) 157
89. Tadaki S., Nozoka T., Yamada S., Ishino M., Morimoto I., Tanaka A., and Kunitomo J.I. J. Pharmacobio. Dyn. 15 (1992) 501
90. Lieb W.A., and Scherf H.J. Klin. Monatsbl. Augenheilk 128 (1956) 686
91. Ubeda A., Montesinos C., Paya M., Terencio C., and Alcaraz M. Free Radical Res. Commun. 18 (1993) 167
92. Ubeda A., Montesinos C., Paya M., and Alcaraz M.J. Free Radical Biol. Med. 15 (1993) 159
93. Martinez L.A., Rios J.L., Paya M., and Alcaraz M.J. Free Radical Biol. Med. 12 (1992) 287
94. Duke J.A. CRC Crit. Rev. Toxicol. 5 (1977) 189
95. Zhang Y.H., Shin J.S., Lee S.S., Kim S.H., and Lee M.K. Planta Med. 63 (1997) 362
96. Wright C.W., Marshall S.J., Russel P.F., Anderson M.M., Phillipson J.D., Kirby G.C., Warhust D.C., and Schiff Jr. P.L. J. Nat. Prod. 63 (2000) 1638
97. Watanabe H. Ikagaku Oyo Kenkyu Zaidan Kenkyu Hokoku 9 (1991) 223
98. Watanabe H., Ikeda M., Watanabe K., and Kikuchi T. Planta Med. 42 (1981) 213
99. Waternabe K. Yao Hsueh T'ung Pao 20 (1985) 522
100. Kimura I., Kimura M., Yoshizaki M., Yanada K., Kadota S., and Kikuchi T. Planta Med. 48 (1983) 43
101. Mustafa M.R., and Achike F.I. Acta Pharmacol. Sinica 21 (2000) 1165
102. Su M.J., Nieh Y.C., Huang H.W., and Chen C.C. Naunyn-Schmiedeberg's Arch. Pharmacol. 349 (1994) 42
103. M. J. Su, C. C. Chen, C. M. Teng, and S. M. Yu, "Use of Dicentrine and its Derivatives for the Treatment of Hypertension, Arrythmia, Thrombosis and Atherosclerosis" Patent-USA-5, 262, 421, 4pp. (1993)
104. Ma W.G., Fukushi Y., Tahara S., and Osawa T. Fitoterapia 71 (2000) 527
105. Yu S.M., Ko F.N., Chueh S.C., Chen J., Chen S.C., Chen C.C., and Teng C.M. Eur. J. Pharmacol. 252 (1994) 29
106. Kondo Y., Imai Y., Hojo H., Endo T., and Nozoe S. J. Pharmacobio. Dyn. 13 (1990) 426
107. Yu S.M., Kang Y.F., Chen C.C., and Teng C.M. Brit. J. Pharmacol. 108 (1993) 1055
108. Adewumi C.O., Monache F.D., and Marques B.B. Bull. Chem. Soc. Ethiopia 3 (1989) 103
109. Nozaka T., Watanabe F., Tadaki S.I., Ishino M., Morimoto I., Kunitomo J.I., Ishii H., and Natori S. Mutat. Res. 240 (1990) 267
110. Chen C.C., Lin C.F., Huang Y.L., Ko F.N., and Teng C.M. J. Nat. Prod. 58 (1995) 1423
111. Mustafa M.R., Mohamad R., Din L., and Wahid S. Phytother. Res. 9 (1995) 555
112. Camacho M.D.R., Kirby G.C., Warhurst D.C., Croft S.L., and Phillipson J.D. Planta Med. 66 (2000) 478
113. Asaruddin M.R., Kiuchi F., and Honda G. Natural Med. 55 (2001) 149
114. Zhou B.N., Johnson R.K., Mattern M.R., Wang X.Y., Hecht S.M., Beck H.T., Ortiz A., and Kingston D.G.I. J. Nat. Prod. 63 (2000) 217
115. Nakai N., Fujii Y., Kobashi K., and Nomura K. Arch. Biochem. Biophys. 239 (1985) 491
116. Fournet A., Munoz V., Manjon A.M., Angelo A., Hocquemiller R., Cortes D., Cavé A., and Bruneton J. J. Ethnopharmacol. 24 (1988) 327
117. Fournet A., Manjon A.M., Munoz V., Angelo A., Bruneton J., Hocquemiller R., Cortes D., and Cavé A. J. Ethnopharmacol. 24 (1988) 337
118. De Arias A.R., Inchausti A., Ascurrat M., Fleitas N., Rodriguez E., and Fournet A. Phytother. Res. 8 (1994) 141
119. S.M. Kupchan and A.J. Liepa, "Cytotoxic Hernandaline" Patent-Brit-1, 373, 400 (1974)
120. Chen S.B., Gao G.Y., Li Y.S., Yu S.C., and Xiao P.G. Planta Med. 68 (2002) 554
121. Chia Y.C., Chen K.S., Chang Y.L., Teng C.M., and Wu Y.C. Bioorg. Med. Chem. Lett. 9 (1999) 3295
122. Abbasoglu U., Sener B., Gunay Y., and Temizer H. Arch. Pharm. (Weinheim) 324 (1991) 379
123. Zhao D.H., Yang X.M., and Sheng B.H. Acta Pharmacol. Sinica 7 (1986) 131
124. Chen Z., Zhang Z., and Wang M. Zhonguo Yaoli Xuebao 6 (1985) 45
125. Ulrichova J., Walterova D., Preininger V., and Simanek V. Planta Med. 48 (1983) 174
126. Wijeratne E.M.K., Gunatilaka A.A.L., Kingston D.G.I., Haltiwanger R.C., and Eggleston D.S. Tetrahedron 51 (1995) 7877
127. S.F. Fakhrutdinov and M.B. Sultanov, Farmakol. Alkaloidov IKH Proizvod, 118 (1972)
128. Shu H.D., and Huang G.P. Acta Pharmacol. Sinica 7 (1986) 198
129. Anderson R.C., and Chen K.K. Fed. Proc. 5 (1946) 163
130. Yamahara J., Sawada T., Kozuka M., and Fujimura H. Shoyakugaku Zasshi 28 (1974) 83
131. Marshall S.J., Russell P.F., Wright C.W., Anderson M.M., Phillipson J.D., Kirby G.C., Warhurst D.C., and Schiff Jr. P.L. Antimicrob. Agents Chemother. 38 (1994) 96
132. Kinoshita K., Morikawa K., Fujita M., and Natori S. Planta Med. 58 (1992) 137
133. Sato T., Kanaho Y., and Fujii T. Cell. Struct. Funct. 5 (1980) 155
134. Yamahara J., Sawada T., Kozuka M., and Fujimura H. Shoyakugaku Zasshi 28 (1974) 96
135. Yasukawa K., Akasu M., Takeuchi M., and Takido M. Oncology 50 (1993) 137
136. Onai N., Tsunokawa Y., Suda M., Watanabe N., Nakamura K., Sugimoto Y., and Kobayashi Y. Planta Med. 61 (1995) 497
137. Fournet A., Barrios A.A., Munoz V., Hocquemiller R., and Cavé A. Phytother. 7 (1993) 281
138. Camacho M.D.R., Phillipson J.D., Croft S.L., Rock P., Marshall S.J., and Schiff P.L.Jr. Phytother. Res. 16 (2002) 432
139. Partride S.J., Russell P.F., Kirby G.C., Warhurst D.C., Phillipson J.D., O'Neill M.J., and Schiff P.L.Jr. J. Pharmacol. Suppl. 41 (1989) 92
140. Angerhofer C.K., Guinaudeau H., Wongpanich V., Pezzuto J.M., and Cordell G.A. J. Nat. Prod. 62 (1999) 59
141. Lambin S., and Bernard J. C. Seances R. Soc. Biol. Res. Fil. 147 (1953) 638
142. Mitscher L.A., Wu W.N., Doskotch R.W., and Beal J.L. Lloydia 35 (1972) 167
143. Ogasawara M., Matsubara T., and Suzuki H. Biol. Pharm. Bull. 24 (2001) 720
144. Fournet A., Ferreira M.E., De Arias A.R., Schinini A., Nakayama H., Torres S., Sanabria R., Guianudeau H., and Bruneton J. Int. J. Antimicrob. Agents 8 (1997) 163
145. Felix J.P., King V.F., Shevell J.L., Garcia M.L., Kaczorowski G.J., Bick I.R.C., and Slaughter R.S. Biochemistry 31 (1992) 11793
146. Nakaoji K., Nayeshiro H., Tanahashi T., Su Y., and Nagakura N. Planta Med. 63 (1997) 425
147. Likhitwitayawuid K., Angerhofer C.K., Cordell G.A., Pezzuto J.M., and Ruangrungsi N. J. Nat. Prod. 56 (1993) 30
148. Protais P., Arbaoui J., Bakkali E.H., Bermejo A., and Cortes D. J. Nat. Prod. 58 (1995) 1475
149. Nakamura K., Tsuchiya S., Sugimoto Y., Sugimura Y., and Yamada Y. Planta Med. 58 (1992) 505
150. Sogawa N., Sogawa C., and Furuta H. Igaku to Seibutsugaku 140 (2000) 69
151. Seow W.K., Nakamura K., Sugimura Y., Sugimoto Y., Yamada Y., Fairlie D.P., and Thong Y.H. Mediators Inflamm. 2 (1993) 199
152. Cortes D., Figadere B., Saez J., and Protais P. J. Nat. Prod. 55 (1992) 1281
153. Catret M., Anselmi E., Ivorra M.D., Elorriaga M., Tur R., and D'Con M.P. J. Pharm. Pharmacol. 50 (1998) 1267
154. Kondo Y., Tacaño F., and Hojo H. Biochem. Pharmacol. 46 (1993) 1887
155. Sun H., Han G.Z., Su C.Y., and Dai S.F. Yao Hsueh Hsueh Pao 25 (1990) 241
156. Akiba S., Kato E., Sato T., and Fujii T. Biochem. Pharmacol. 44 (1992) 45
157. Kondo Y., Imari Y., Hojo H., Hashimoto Y., and Nozoe S. Int. J. Immunopharmacol. 14 (1992) 1181
158. Anselmi E., Gomez-Lobo M.D., Blazquez M.A., Zafra-Polo M.C., and D'Ocon M.P. Pharmazie 49 (1994) 440
159. Kamiya T., Sugimoto Y., and Yamada Y. Planta Med. 59 (1993) 475
160. Matsuno T., Orita K., Edashige K., Kobuchi H., Sato E.F., Inouye B., Inoue M., and Utsumi K. Biochem. Pharmacol. 39 (1990) 1255
161. D'Ocon P., Blazquez M.A., Bermejo A., and Anselmi E. J. Pharm. Pharmacol. 44 (1992) 579
162. Ferdous A.J., Islam M.O., Hasan C.M., and Islam S.N. Fitoterapia 63 (1992) 549
163. Khan M.R., Kihara M., and Omoloso A.D. Pharmaceutical Biol. 41 (2003) 277
164. Villar A., Rios J.L., Recio M.C., Cortes D., and Cavé A. Planta Med. 52 (1986) 556
165. Zhang Z., El Sohly H., Jacob M.R., Pasco D.S., Walker L.A., and Clark A.M. J. Nat. Prod. 65 (2002) 856
166. Chulia S., Ivorra M.D., Lugnier C., Vila E., Noguera M.A., and D'Ocon P. Brit. J. Pharmacol. 113 (1994) 1377
167. Paulova H., Kovar J., Plocek J., and Slavik J. Collect. Czech. Chem. Commun. 52 (1987) 2338Q
168. Mercier F., and Delphaut J. C. R. Soc. Biol. 118 (1935) 168
169. Mourey R.J., Dawson T.M., Barrow R.X., Enna A.E., and Synder S.H. J. Amer. Soc. Pharmacol. Exp. Ther. 42 (1992) 619
170. Chen K.S., Ko F.N., Teng C.M., and Wu Y.C. J. Nat. Prod. 59 (1996) 531
171. Leboeuf M., Cavé A., Provost J., Tiberghein R., and Forgacs P. Ann. Pharm. Fr. 38 (1980) 537
172. Chen W.Y., Ko F.N., Wu Y.C., Lu S.T., and Teng C.M. J. Pharm. Pharmacol. 46 (1994) 380
173. Fashuddin B.A., Shanty V., and Atan M.S. Pertanika 14 (1991) 355
174. Ratsimamanoa-Urverg S., Rasoanaivo P., Ramiaramanana L., Milijaona R., Rafatro H., Verdier F., Rakoto-Ratismananga A., and Le Bras J. Planta Med. 58 (1992) 540
175. Frappier F., Jossang A., Soudon J., Calvo F., Rasoanaivo P., Ratsimamanga-Urverg F., Saez J., Schrevel J., and Grellier P. Antimicrob. Agents Chemother. 40 (1996) 1476
176. Fournet A., Inchausti A., Yaluff G., De Arias A.R., Guinaudeau H., Bruneton J., Breidenbach M.A., Karplus P.A., and Faerman C.H. J. Enzyme Inhibit. 13 (1998) 1
177. Lin L.Z., Shieh H.L., Angerhofer C.K., Pezzuto J.M., Cordell G.A., Xue L., Johnson M.E., and Ruangrungsi N. J. Nat. Prod. 56 (1993) 22
178. Jin C.M., Lee J.J., Yin S.Y., Kim Y.M., Kim Y.K., Rhu S.Y., and Lee M.K. Kor. J. Pharmacog. 34 (2003) 55
179. Chang G.J., Wu M.H., Wu Y.C., and Su M.J. Brit. J. Pharmacol. 118 (1996) 1571
180. Nissanka A.P.K., Karunaratne V., Bandara B.M.R., Kumar V., Nakanishi T., Nishi M., Inada A., Tillekeratne L.M.V., Wijesundara D.S.A., and Gunatilaka A.A.L. Phytochemistry 56 (2001) 857
181. Hufford C.D., Fundeburk M.J., Morgan J.M., and Robertson L.W. J. Pharm. Sci. 64 (1975) 789
182. Simeon S., Rios J.L., and Villar A. Pharmazie 45 (1990) 442
183. Hufford C.D., Sharma A.S., and Oguntimein B.O. J. Pharm. Sci. 69 (1980) 1180
184. Villar A., Mares M., Rios J.L., Canton E., and Gobernado M. Pharmazie 42 (1987) 248
185. Hui Y.H., Ruprecht J.K., Liu Y.M., Anderson J.E., Smith D.L., Chang C.J., and McLaughlin J.L. J. Nat. Prod. 52 (1989) 463
186. Rzedowski M., Furmanowa M., and Molak W. Acta Pol. Pharm. 42 (1985) 3000
187. Clark A.M., Jurgens T.M., and Hufford C.D. Phytother. Res. 4 (1990) 11
188. Queiroz E.F., Roblot F., Cavé A., Paulo M.D.Q., and Fournet A. J. Nat. Prod. 59 (1996) 438
189. Waechter A.I., Cace A., Hocquemiller R., Bories C., Munoz V., and Fournet A. Phytother. Res. 13 (1999) 175
190. Fevier A., Ferreira M.E., Fournet A., Valuff G., Inchausti A., De Arias A.R., Hocquemiller R., and Waechter A.I. Planta Med. 65 (1999) 47
191. Weniger B., Aragon R., Deharo E., Bastida J., Codina C., Lobstein A., and Anton R. Pharmazie 55 (2000) 867
192. Harrigan G.G., Gunatilaka A.A.L., Kingston D.G.I., Chan G.W., and Johnson R.K. J. Nat. Prod. 57 (1994) 68
193. Pabuccuoglu V., Rozwadowsak M.D., Brossi A., Clark A.M., Hufford C.D., George C., and Flippen-Anderson J.L. Arch. Pharm. (Weinheim) 324 (1991) 29
194. Clark A.M., Watson E.S., Ashfaq M.K., and Hufford C.D. Pharmaceut. Res. 4 (1987) 495
195. Warthen D., Gooden E.L., and Jacobson M. J. Pharm. Sci. 58 (1969) 637
196. Yang T.H., Chen C.M., Lu C.S., and Liao C.L. J. Chin. Chem. Soc. 19 (1972) 143
197. Wu Y.C., Chen C.H., Yang T.H., Lu S.T., McPhail D.R., McPhail A.T., and Lee K.H. Phytochemistry 28 (1989) 2191
198. Wu Y.C., Duh C.Y., Wang S.K., Chen K.S., and Yang T.H. J. Nat. Prod. 53 (1990) 1327
199. Wu Y.C., Chang G.Y., Duh C.Y., and Wang S.K. Phytochemistry 33 (1993) 497
200. Kim Y.K., and Ryu S.Y. Planta Med. 65 (1999) 291
201. Wu Y.C., Lu S.T., Chang J.J., and Lee K.H. Phytochemistry 27 (1988) 1563
202. Dong X.P., Mondranondra I.O., Che C.T., Fong H.H.S., and Farnsworth N.R. Pharmaceut. Res. 6 (1989) 637
203. Mondranonda I.O., Che C.T., Rimando A.M., Vajrodaya S., Fong H.H.S., and Farnsworth N.R. Pharmaceut. Res. 7 (1990) 1269
204. Wu Y.C., Liou Y.F., Lu S.T., Chen C.H., Chang J.J., and Lee K.H. Planta Med. 55 (1989) 163
205. Ogura M., Cordell G.A., and Farnsworth N.R. Phytochemistry 17 (1978) 957
206. I. Borup and D. G. I. Kingston, Abstr. Joint Meeting American Society of Pharmacognosy and Society for Economic Botany, Boston, July 13-17, 31 (1981)
207. Borup-Grochtmann I., and Kingston D.G.I. J. Nat. Prod. 45 (1982) 102
208. Lin C.H., Yang C.M., Ko F.N., Ko N., Wu Y.C., and Teng C.M. Brit. J. Pharmacol. 113 (1994) 1464
209. Lin C.H., Chang G.Y., Su M.J., Wu Y.C., Teng C.M., and Ko F.N. Brit. J. Pharmacol. 113 (1994) 275
210. Teng C.M., Ko J.N., and Lin C.H. J. Chin. Med. 5 (1994) 11
211. Nozaka T., Morimoto I., Ishino M., and Natori S. Chem. Pharm. Bull. 36 (1988) 2259
212. Pyo M.K., Yun-Choi H.S., and Hong Y.J. Planta Med. 69 (2003) 267
213. Chulia S., Noguera M.A., Ivorra M.D., Cortes D., and D'Ocon M.P. Pharmacology 50 (1995) 380
214. Woo S.H., Sun N.J., Cassady J.M., and Snapka R.M. Biochem. Pharmacol. 57 (1999) 1141
215. Woo S.H., Reynolds M.C., Sun N.J., Cassady J.M., and Snapka R.M. Biochem. Pharmacol. 54 (1997) 467
216. Chang F.R., Chen K.S., Ko F.N., Teng C.M., and Wu Y.C. Chin. Pharm. J. (Taipei) 47 (1995) 483
217. Achenbach H., and Hemrich H. Phytochemistry 30 (1991) 1265
218. Han B.H., Park M.H., and Han Y.N. Yakhak Hoe Chi 37 (1993) 143
219. Hsieh T.J., Chang F.R., Chia Y.C., Chen C.Y., Chiu H.F., and Wu Y.C. J. Nat. Prod. 64 (2001) 616
220. Han B.H., and Park M.H. Arch. Pharm. Res. 10 (1987) 208
221. Saxena N.K., and Bhakuni D.S. J. Indian Chem. Soc. 57 (1980) 773
222. Funayama S., and Hikino H. Heterocycles 15 (1981) 1239
223. Guh J.H., Ko F.N., Yu S.M., Wu Y.C., and Teng C.M. Eur. J. Pharmacol. 279 (1995) 33
224. Hsu C.Y.H., and Chen C.L. Holzforschung 45 (1991) 325
225. Stigliani J.L., Boustie J., Amoros M., Montanha J., Payard M., and Girre L. Pharm. Pharmacol. Commun. 4 (1998) 65
226. Chen C.C., Huang Y.L., Ou J.C., Su M.J., Yu S.M., and Teng C.M. Planta Med. 57 (1991) 406
227. Montenegro H., Gutierrez M., Romero L., Ortega Barria E., Capson T.L., and Rios L.C. Planta Med. 69 (2003) 677
228. Indra B., Matsunaga K., Hoshino O., Suzuki M., Ogasawara H., Ishiguro M., and Ohizumi Y. Can. J. Physiol. Pharmacol. 80 (2002) 198
229. Partridge S.J., Russell P.F., Kirby G.C., Bray D.H., Warhurst D.C., Phillipson J.D., O'Neill M.J., and Schiff Jr. P.L. J. Pharm. Pharmacol. Suppl. 40 (1988) 53
230. Ekong R., Partridge S.J., Anderson M.M., Kirby G.C., Warhurst D.C., Russell P.F., and Phillipson J.D. Ann. Trop. Med. Parasitol. 85 (1991) 205
231. Dasgupta S., Ray A.B., Bhattacharya S.K., and Bose R. J. Nat. Prod. 42 (1979) 399
232. Paulo M.Q., Barbosa-Filho J.M., Lima E.O., Maia R.F., Barbosa B.B.C.R., and Kaplan M.A.C. J. Ethnopharmacol. 36 (1992) 39
233. Morais L.C.S.L., Barbosa-Filho J.M., and Almeida R.N. J. Ethnopharmacol. 62 (1998) 57
234. Banning J.W., Uretsky N.J., Patil P.N., and Beal J.L. Life Sci. 26 (1980) 2083
235. Nakaoji K., Nayeshiro H., and Tanahashi T. Biol. Pharm. Bull. 20 (1997) 586
236. Martin M.L., Diaz M.T., Montero M.J., Prieto P., Roman L.S., and Cortes D. Planta Med. 59 (1993) 63
237. Martin M.L., Sagredo J.A., Morais J.M., Montero J., Sanchez M.T., and San Roman L. J. Pharm. Pharmacol. 40 (1988) 801
238. Likhitwitayawuid K., Angerhofer C.K., Chai H.B., Pezzuto J.M., Cordell G.A., and Ruangrungsi N. J. Nat. Prod. 56 (1993) 1468
239. L. R. Meyerson, K. D. McMurtrey, and V. E. Davis, Neurochem. Res. 239 (1978)
240. Bermejo A., Protais P., Blazouez M.A., Rao K.S., Zafra-Polo M.C., and Cortes D. Nat. Prod. Lett. 6 (1995) 57
241. Kimura I., Chui L.H., Fujitani K., Kikuchi T., and Kimura M. Jap. J. Pharmacol. 50 (1989) 75
242. Manandhar M.D., Shoeb A., Kapil R.S., and Popli S.P. Indian J. Chem. 17B (1979) 411
243. Wu W.N., Beal J.L., and Doskotch R.W. Lloydia 40 (1977) 508
244. Gharbo S.A., Beal J.L., Doskotch R.W., and Mitscher L.A. Lloydia 36 (1973) 349
245. Mircheva I. Suvrem Med. 28 (1977) 33
246. Li C.L. Yao Hsueh T'ung Pao 17 (1982) 83
247. Han R. Yao Hsueh Hsueh Pao 17 (1982) 955
248. Suffness M., and Douros J.D. In: Cassady J.M., and Douros J.D. (Eds). Miscellaneous Natural Products with Antitumor Activity (1980), Academic Press, N.Y. 465-487
249. Damyanova M., and Stoichkov I. Probl. Onkol. 12 (1984) 45
250. I. Khamdamov, Farmakol. Prir. Veschestv 29 (1978)
251. Popov D., and Todorov D. Dokl. Bolg. Akad. Nauk. 33 (1980) 1151
252. Seifert F., Todorov D.K., Hutter K.J., and Zeller W.J. J. Cancer Res. Clin. Oncol. 122 (1996) 707
253. Chen G., Ramachandran C., and Krishan A. Cancer Res. 53 (1993) 2544
254. Allen L.M., and Creaven P.J. Cancer Res. 33 (1973) 3112
255. Todorov D.K., and Damyanova M. Dokl. Bolg. Akad. Nauk. 28 (1975) 709
256. Chen G., Zeller W.J., and Todorov D.K. Anticancer Res. 13 (1993) 1269
257. Chen G., Todorov D.K., and Zeller W.J. Cancer Lett. 62 (1992) 172
258. Astardzhieva Z., and Stoichkov I. Onkologiya (Sofia) 16 (1979) 131
259. Todorov D.K., and Delicanstantinos G. Dokl. Bolg. Akad. Nauk. 34 (1981) 433
260. Todorov D.K., and Delicanstantinos G. Experientia 38 (1982) 857
261. Chen G., Teicher V.A., and Frei E.I. Anticancer Res. 16 (1996) 3499
262. Chen G., and Zeller W.J. Anticancer Res. 13 (1993) 219
263. Khadzhidekova V., Ivanov B., Koleva M., and Mincheva A. Onkologiya 20 (1983) 95 (Sofia)
264. Astardzhieva I., Stoichkov I., and Mircheva I. Eksp. Med. Morfol. 16 (1977) 151
265. Allen L.M., and Creaven P.J. J. Pharm. Sci. 63 (1974) 474
266. Popov D., and Todorov D. Dokl. Bolg. Akad. Nauk. 33 (1980) 437
267. Mircheva I. Eksp. Onkol 6 (1984) 48
268. Chen G., and Waxman D.J. J. Pharmacol. Exp. Ther. 274 (1995) 1271
269. Creasey W.A. Biochem. Pharmacol. 25 (1976) 1887
270. Liao L.L.H. Proc. Natl. Sci. Counc. Repub. China 4 (1980) 285
271. Rao G.N., Palmer T.E., Balk M.W., Thompson G.W., and Glaza S.M. US Ntis. PB Rep. PB-82-166299 82 (1982) 2088
272. Rosencweig M., Von Hoff D.D., Staquet M.J., Schein O.S., Penta J.S., Goldin A., Muggia F.M., Freireich E.J., and De Vita V.T.Jr. Cancer Clin. Trials 4 (1981) 21
273. Mircheva I., and Stoichkov I. Farmakol. Toksikol. 40 (1977) 448 (Moscow)
274. Mircheva I., and Stoichkov I. Farmatsiya 27 (1977) 19 (Sofia)
275. Todorov D.K., Getov H.M., Harionova M.V., and Maneva K.M. C. R. Acad. Bulg. Sci. 34 (1981) 445