Electrophysiological mechanisms for antiarrhythmic efficacy and positive inotropy of liriodenine, a natural aporphine alkaloid from Fissistigma glaucescens

British Journal of Pharmacology

Volumn 118, Issue 7, 1996, Pages 1571-1583

  Chang, Gwo Jyh ^a   Wu, Mei Hwan ^a   Wu, Yang Chang ^b   Su, Ming Jai ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cardiac arrhythmia; Cardiac myocytes; Fissistigma glaucescens; Liriodenine; Na+, Ca2+ and K+ currents; Positive inotropy; Quinidine

Indexed keywords

4 AMINOPYRIDINE; APORPHINE DERIVATIVE; CARBACHOL; LIRIODENINE; PLANT EXTRACT; PRAZOSIN; PROPRANOLOL; QUINIDINE; SODIUM CHANNEL; SODIUM ION; VERAPAMIL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFICACY; DRUG MECHANISM; ELECTROPHYSIOLOGY; HEART ARRHYTHMIA; HEART BEAT; HEART MUSCLE CONTRACTILE FORCE; HEART PERFUSION; HEART RIGHT ATRIUM; HEART VENTRICLE; HEART VENTRICLE ARRHYTHMIA; INOTROPISM; MALE; MEMBRANE STEADY POTENTIAL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; STEADY STATE; VOLTAGE CLAMP;

EID: 0030010878     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15577.x     Document Type: Article

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