-
1
-
-
0028117270
-
Drug resistance: Genotype versus phenotype - Thirty-second G. H. A. Clowes Memorial Award Lecture
-
Biedler JL: Drug resistance: genotype versus phenotype - thirty-second G. H. A. Clowes Memorial Award Lecture. Cancer Res 54: 666-678, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 666-678
-
-
Biedler, J.L.1
-
2
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman MM and Pastan I: Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62: 385-427, 1993.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
3
-
-
0019430432
-
Overcoming of vincristine resistance in P388 leukemia in viro and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
-
Tsuruo T, Iida H, Tsukagoshi S and Sakurai Y: Overcoming of vincristine resistance in P388 leukemia in viro and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res 41: 1967-1972, 1981.
-
(1981)
Cancer Res
, vol.41
, pp. 1967-1972
-
-
Tsuruo, T.1
Iida, H.2
Tsukagoshi, S.3
Sakurai, Y.4
-
4
-
-
0025007511
-
Pharmacology of drugs that alter multidrug resistance in cancer
-
Ford JM and Hait WN: Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 42: 155-159, 1990.
-
(1990)
Pharmacol Rev
, vol.42
, pp. 155-159
-
-
Ford, J.M.1
Hait, W.N.2
-
5
-
-
0026051296
-
P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil
-
Miller TP, Grogan TM, Dalton WS, Spier CM, Scheper RJ and Salmon SE: P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil. J Clin Oncol 9: 17-24, 1991.
-
(1991)
J Clin Oncol
, vol.9
, pp. 17-24
-
-
Miller, T.P.1
Grogan, T.M.2
Dalton, W.S.3
Spier, C.M.4
Scheper, R.J.5
Salmon, S.E.6
-
6
-
-
0026426153
-
Systemic toxic effects associated with high-dose verapamil infusion and chemotherapy administration
-
Pennock GD, Dalton WS, Roeske WR, Appleton CP, Mosley K, Plezia P, Miller TP and Salmon SE: Systemic toxic effects associated with high-dose verapamil infusion and chemotherapy administration. J Natl Cancer Inst 83: 105-110, 1991.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 105-110
-
-
Pennock, G.D.1
Dalton, W.S.2
Roeske, W.R.3
Appleton, C.P.4
Mosley, K.5
Plezia, P.6
Miller, T.P.7
Salmon, S.E.8
-
7
-
-
0027165416
-
Modulation of multidrug resistance: At the threshold
-
Sikic BI: Modulation of multidrug resistance: at the threshold. J Clin Oncol 11: 1629-1635, 1993.
-
(1993)
J Clin Oncol
, vol.11
, pp. 1629-1635
-
-
Sikic, B.I.1
-
8
-
-
0021852930
-
Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies
-
Kartner N, Evernden-Porelle D, Bradley G and Ling V: Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature 316: 820-823, 1985.
-
(1985)
Nature
, vol.316
, pp. 820-823
-
-
Kartner, N.1
Evernden-Porelle, D.2
Bradley, G.3
Ling, V.4
-
9
-
-
0023819244
-
Monoclonal antibody JSB-1 detects a highly conserved epitope on the P-glycoprotein associated with multidrug-resistance
-
Scheper RJ, Bulte JWM, Brakkee JGP, Quak JJ, van der School E, Balm AJM, Meijer CJLM, Broxterman HJ, Kuiper CM, Lankelma J and Pinedo HM: Monoclonal antibody JSB-1 detects a highly conserved epitope on the P-glycoprotein associated with multidrug-resistance. Int J Cancer 42: 389-394, 1988.
-
(1988)
Int J Cancer
, vol.42
, pp. 389-394
-
-
Scheper, R.J.1
Bulte, J.W.M.2
Brakkee, J.G.P.3
Quak, J.J.4
Van der School, E.5
Balm, A.J.M.6
Meijer, C.J.L.M.7
Broxterman, H.J.8
Kuiper, C.M.9
Lankelma, J.10
Pinedo, H.M.11
-
10
-
-
0024596650
-
Induced multidrug resistance in murine leukemia L1210 and associated changes in a surfance membrane glycoprotein
-
Volm M, Bak MJ, Efferth T and Mattern J: Induced multidrug resistance in murine leukemia L1210 and associated changes in a surfance membrane glycoprotein. J Cancer Res Clin Oncol 115: 17-24, 1989.
-
(1989)
J Cancer Res Clin Oncol
, vol.115
, pp. 17-24
-
-
Volm, M.1
Bak, M.J.2
Efferth, T.3
Mattern, J.4
-
12
-
-
0023889448
-
Tissue distribution of p-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody. MRK16
-
Sugawara I, Kataoka I, Morishita Y, Hamada H, Tsuruo T, Itoyama S and Mori S: Tissue distribution of p-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody. MRK16. Cancer Res 48: 1926-1929, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 1926-1929
-
-
Sugawara, I.1
Kataoka, I.2
Morishita, Y.3
Hamada, H.4
Tsuruo, T.5
Itoyama, S.6
Mori, S.7
-
13
-
-
0026426196
-
Clinical relevance of immunohistochemical detection of multidrug resistance p-glycoprotein in breast carcinoma
-
Venelle P, Meissonnier F, Fonck Y, Feillel V, Dionet C, Kwiatkowski F, Plagne R and Chassagne J: Clinical relevance of immunohistochemical detection of multidrug resistance p-glycoprotein in breast carcinoma. J Natl Cancer Inst 83: 111-116, 1991.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 111-116
-
-
Venelle, P.1
Meissonnier, F.2
Fonck, Y.3
Feillel, V.4
Dionet, C.5
Kwiatkowski, F.6
Plagne, R.7
Chassagne, J.8
-
14
-
-
0025739785
-
Relationship of the expression of the multidrng resistance gene product (p-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis
-
Weinstein RS, Jakate SM, Dominguez JM, Lebovitz M, Koukoulis GK, Kuszak JR, Klusens LF, Grogan TM, Saclarides TJ, Roninson IB and Coon JS: Relationship of the expression of the multidrng resistance gene product (p-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis. Cancer Res 51: 2720-2726, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 2720-2726
-
-
Weinstein, R.S.1
Jakate, S.M.2
Dominguez, J.M.3
Lebovitz, M.4
Koukoulis, G.K.5
Kuszak, J.R.6
Klusens, L.F.7
Grogan, T.M.8
Saclarides, T.J.9
Roninson, I.B.10
Coon, J.S.11
-
15
-
-
0026781491
-
Clinical correlates of MDR1 (pglycoprotein) gene expression in ovarian and small-cell lung carcinomas
-
Holzmayer TA, Hilsenbeck S, von Hoff DD and Roninson IB: Clinical correlates of MDR1 (pglycoprotein) gene expression in ovarian and small-cell lung carcinomas. J Natl Cancer Inst 84: 1486-1491, 1992.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1486-1491
-
-
Holzmayer, T.A.1
Hilsenbeck, S.2
Von Hoff, D.D.3
Roninson, I.B.4
-
16
-
-
0022602456
-
Tumor heterogeneity and drug resistance
-
Dexter DL and Leith JT: Tumor heterogeneity and drug resistance. J Clin Oncol 4: 244-257, 1986.
-
(1986)
J Clin Oncol
, vol.4
, pp. 244-257
-
-
Dexter, D.L.1
Leith, J.T.2
-
17
-
-
0000657267
-
Thalicarpine, a new hypotensive alkaloid from Thalictrum dasycarpum
-
Kupchan SM, Chakravarti KK, Yokoyoma N: Thalicarpine, a new hypotensive alkaloid from Thalictrum dasycarpum. J Pharm Sci 52: 985-988, 1963.
-
(1963)
J Pharm Sci
, vol.52
, pp. 985-988
-
-
Kupchan, S.M.1
Chakravarti, K.K.2
Yokoyoma, N.3
-
19
-
-
0026590726
-
Antitumor activity of thaliblastine (NSC-68075) in experimental ovarian tumor cells sensitive and resistant to cisplatin
-
Chen G, Todorov DK and Zeller WJ: Antitumor activity of thaliblastine (NSC-68075) in experimental ovarian tumor cells sensitive and resistant to cisplatin. Cancer Lett 62: 173-177, 1988.
-
(1988)
Cancer Lett
, vol.62
, pp. 173-177
-
-
Chen, G.1
Todorov, D.K.2
Zeller, W.J.3
-
20
-
-
0027331851
-
Collateral sensitivity to thaliblastine and/or hyperthermia exhibited by a rat ovarian tumor cell line selected for resistance to cisplatin
-
Chen G, Zeller WJ and Todorov DK: Collateral sensitivity to thaliblastine and/or hyperthermia exhibited by a rat ovarian tumor cell line selected for resistance to cisplatin. Anticancer Res 13: 1269-1276, 1993.
-
(1993)
Anticancer Res
, vol.13
, pp. 1269-1276
-
-
Chen, G.1
Zeller, W.J.2
Todorov, D.K.3
-
21
-
-
0027322989
-
Thaliblastine, a plant alkaloid, circumvents multidrug resistance by direct binding to pglycoprotein
-
Chen G, Ramachandran C and Krishan A. Thaliblastine, a plant alkaloid, circumvents multidrug resistance by direct binding to pglycoprotein. Cancer Res 53: 2544-2547, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 2544-2547
-
-
Chen, G.1
Ramachandran, C.2
Krishan, A.3
-
22
-
-
0029151639
-
Complete reversal by thaliblastine (TBL) of 490fold adriamycin (AdR) resistance in multidrug resistant (MDR) human breast cancer cells. Evidence that multiple biochemical changes in MDR cells need not correspond to multiple functional determinants for drug resistance
-
Chen G and Waxman DJ: Complete reversal by thaliblastine (TBL) of 490fold adriamycin (AdR) resistance in multidrug resistant (MDR) human breast cancer cells. Evidence that multiple biochemical changes in MDR cells need not correspond to multiple functional determinants for drug resistance. J Pharmacol Exp Ther 274: 1271-1277, 1995.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 1271-1277
-
-
Chen, G.1
Waxman, D.J.2
-
23
-
-
0025562606
-
Mechanisms of multidrug resistance in human tumor cells. the roles of p-glycoprotein, DNA topoisomerase II, and other factors
-
Beck WT: Mechanisms of multidrug resistance in human tumor cells. The roles of p-glycoprotein, DNA topoisomerase II, and other factors. Cancer Treat Rev 17(Suppl. A): 11-20, 1990.
-
(1990)
Cancer Treat Rev
, vol.17
, Issue.SUPPL. A
, pp. 11-20
-
-
Beck, W.T.1
-
25
-
-
0026676488
-
The anthrapyrazoles: A new class of compounds with clinical activity in breast cancer
-
Judson IR: The anthrapyrazoles: a new class of compounds with clinical activity in breast cancer. Semin Oncol 19: 687-694, 1992.
-
(1992)
Semin Oncol
, vol.19
, pp. 687-694
-
-
Judson, I.R.1
-
26
-
-
0023037085
-
Overexpression of a novel anionic glutathione transferase in multidrugresistant human breast cancer cells
-
Batist G, Tulpule A, Sinha BK, Katkis AG, Myers CE and Cowan KH: Overexpression of a novel anionic glutathione transferase in multidrugresistant human breast cancer cells. J Biol Chem 267: 15544-15541, 1986.
-
(1986)
J Biol Chem
, vol.267
, pp. 15544-115541
-
-
Batist, G.1
Tulpule, A.2
Sinha, B.K.3
Katkis, A.G.4
Myers, C.E.5
Cowan, K.H.6
-
27
-
-
0023264802
-
Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancel cells
-
Fairchild CR, Ivy SP, Kao-Shan CS, Whang-Pong J, Rosen N, Israel MA, Melera PW, Cowan KH and Coldmith EM: Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancel cells. Cancer Res 47: 5141-5148, 1987.
-
(1987)
Cancer Res
, vol.47
, pp. 5141-5148
-
-
Fairchild, C.R.1
Ivy, S.P.2
Kao-Shan, C.S.3
Whang-Pong, J.4
Rosen, N.5
Ma, I.6
Melera, P.W.7
Cowan, K.H.8
Coldmith, E.M.9
-
28
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
-
Mosmann T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J Immunol Methods 65: 55-65, 1983.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-65
-
-
Mosmann, T.1
-
29
-
-
0023767544
-
Role of the glutathione redox cycle in acquired and de novo multidrug resistance
-
Kramer RA, Zakher J and Kim G: Role of the glutathione redox cycle in acquired and de novo multidrug resistance. Science 241: 694-697, 1988.
-
(1988)
Science
, vol.241
, pp. 694-697
-
-
Kramer, R.A.1
Zakher, J.2
Kim, G.3
-
30
-
-
0025228358
-
Editorial: Multidrug resistance associated with altered topoisomerase II activity - Topoisomerase II as targets for rational drug design
-
Morrow CS and Cowan KH: Editorial: Multidrug resistance associated with altered topoisomerase II activity - topoisomerase II as targets for rational drug design. J Natl Cancer Inst 82: 638-639, 1990.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 638-639
-
-
Morrow, C.S.1
Cowan, K.H.2
-
31
-
-
0023712807
-
DNA strand breaks produced by etoposide (VP-16, 213) in sensitive and resistant human breast tumor cells: Implications for the mechanisms of action
-
Sinha BK, Haim N, Durse L, Kerrigan D and Pommier Y: DNA strand breaks produced by etoposide (VP-16, 213) in sensitive and resistant human breast tumor cells: Implications for the mechanisms of action. Cancer Res 48: 5096-5100, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 5096-5100
-
-
Sinha, B.K.1
Haim, N.2
Durse, L.3
Kerrigan, D.4
Pommier, Y.5
-
32
-
-
0018387446
-
Promotion of microtubule assembly in vitro by taxol
-
Schiff PB, Fant J and Horwitz SB: Promotion of microtubule assembly in vitro by taxol. Nature 22, 665-667, 1979.
-
(1979)
Nature
, vol.22
, pp. 665-667
-
-
Schiff, P.B.1
Fant, J.2
Horwitz, S.B.3
-
33
-
-
0027537911
-
Phase II study of taxol, merbarone, and piroxantrone in stage IV non-smallcell lung cancer: The eastern cooperative oncology group results
-
Chang AY, Kim K, Glick J, Anderson T, Karp D and Johnson D: Phase II study of taxol, merbarone, and piroxantrone in stage IV non-smallcell lung cancer: the eastern cooperative oncology group results. J Natl Cancer Inst 85: 388-394, 1993.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 388-394
-
-
Chang, A.Y.1
Kim, K.2
Glick, J.3
Anderson, T.4
Karp, D.5
Johnson, D.6
-
34
-
-
0026354712
-
Phase II trial of taxol an active drug in the treatment of metastatic breast cancer
-
Holmes FA, Walters R, Theriault RL, Forman AD, Newton LK, Raher MN, Buzdar AU, Frye DK and Hortobagyi ON: Phase II trial of taxol an active drug in the treatment of metastatic breast cancer. J Natl Cancer Inst 83: 1797-1805, 1991.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 1797-1805
-
-
Holmes, F.A.1
Walters, R.2
Theriault, R.L.3
Forman, A.D.4
Newton, L.K.5
Raher, M.N.6
Buzdar, A.U.7
Frye, D.K.8
Hortobagyi, O.N.9
-
35
-
-
0027517847
-
Cytotoxic studies of paclitaxel (taxol) in human cell lines
-
Liehmann JE, Cook JA, Lipschultz C, Teague D, Fisher J and Mitchell JB: Cytotoxic studies of paclitaxel (taxol) in human cell lines. Br J Cancer 68: 1104-1109, 1993.
-
(1993)
Br J Cancer
, vol.68
, pp. 1104-1109
-
-
Liehmann, J.E.1
Cook, J.A.2
Lipschultz, C.3
Teague, D.4
Fisher, J.5
Mitchell, J.B.6
-
36
-
-
0028175116
-
The influence of cremophor EL on the cell cycle effects of paclitaxel (taxol) in human tumor cell lines
-
Liehmann JE, Cook JA, Lipschultz C, Teague D, Fisher J and Mitchell JB: The influence of cremophor EL on the cell cycle effects of paclitaxel (taxol) in human tumor cell lines. Cancer Chemother Pharmacol 33: 331339, 1994.
-
(1994)
Cancer Chemother Pharmacol
, vol.33
, pp. 331339
-
-
Liehmann, J.E.1
Cook, J.A.2
Lipschultz, C.3
Teague, D.4
Fisher, J.5
Mitchell, J.B.6
-
37
-
-
0028983396
-
Paclitaxel (taxol) inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells
-
Danesi R, Figg WD, Reed E and Myers CE: Paclitaxel (taxol) inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells. Mol Pharmacol 47: 1106-1111, 1995.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1106-1111
-
-
Danesi, R.1
Figg, W.D.2
Reed, E.3
Myers, C.E.4
-
38
-
-
0028882740
-
Failure to dephosphorilate retinoblastoma protein in drug-resistant cells
-
Dou QP and Lui WY: Failure to dephosphorilate retinoblastoma protein in drug-resistant cells. Cancer Res 55: 5222-5225, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 5222-5225
-
-
Dou, Q.P.1
Lui, W.Y.2
-
39
-
-
0038134267
-
Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats
-
Cowan KH, Batist G, Tulpule A, Sinha BK and Myers CE: Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats. Proc Natl Acad Acad Sci USA 83: 9328-9332, 1986.
-
(1986)
Proc Natl Acad Acad Sci USA
, vol.83
, pp. 9328-9332
-
-
Cowan, K.H.1
Batist, G.2
Tulpule, A.3
Sinha, B.K.4
Myers, C.E.5
-
40
-
-
0016165988
-
The interaction of the antineoplastic drug thalicarpine with aniline hydroxylase and microsomal cytochrome of rat liver
-
Creaven PJ, Allen LM and Williams CP: The interaction of the antineoplastic drug thalicarpine with aniline hydroxylase and microsomal cytochrome of rat liver. Xenobiotica 4: 255-261, 1974.
-
(1974)
Xenobiotica
, vol.4
, pp. 255-261
-
-
Creaven, P.J.1
Allen, L.M.2
Williams, C.P.3
-
41
-
-
0027954464
-
Taxol metabolism by human liver microsomes: Identification of cytochrome P450 isozymes involved in its biotransformation
-
Cresteil T, Monsarrat B, Alvinerie P, Treluyer JM, Vieira I and Wright H M: Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation. Cancer Res 54: 386-392, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 386-392
-
-
Cresteil, T.1
Monsarrat, B.2
Alvinerie, P.3
Treluyer, J.M.4
Vieira, I.5
Wright, H.M.6
-
42
-
-
0027533571
-
Restoration of taxol sensitivity of multidrug resistant cells by the cyclosporine SDZ PSC 833 and the cyclopeptolide SDZ 280-446
-
Jachez B, Nordmann R and Loor F: Restoration of taxol sensitivity of multidrug resistant cells by the cyclosporine SDZ PSC 833 and the cyclopeptolide SDZ 280-446. J Natl Cancer Inst 85: 478-483, 1993.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 478-483
-
-
Jachez, B.1
Nordmann, R.2
Loor, F.3
-
43
-
-
0025836891
-
Anthrapyrazol CI941: A highly active new agent in the treatment of advanced breast cancer
-
Talbot DC, Smith IE, Judson MI, Calver AH and Ashley SE: Anthrapyrazol CI941: a highly active new agent in the treatment of advanced breast cancer. J Clin Oncol 9: 2141-2147, 1991.
-
(1991)
J Clin Oncol
, vol.9
, pp. 2141-2147
-
-
Talbot, D.C.1
Smith, I.E.2
Judson, M.I.3
Calver, A.H.4
Ashley, S.E.5
-
44
-
-
0022449184
-
Resistance to anthrapyrazols and anthracyclines in multidrug-resistant P388 murine leukemia cells: Reversal by calcium blockers and calmodulin antagonists
-
Klohs WD, Steinkampf RW, Havlick MJ and Jackson RC: Resistance to anthrapyrazols and anthracyclines in multidrug-resistant P388 murine leukemia cells: reversal by calcium blockers and calmodulin antagonists. Cancer Res 46: 4352-4356, 1986.
-
(1986)
Cancer Res
, vol.46
, pp. 4352-4356
-
-
Klohs, W.D.1
Steinkampf, R.W.2
Havlick, M.J.3
Jackson, R.C.4
|