Structure-activity relationship on (±)-nantenine derivatives in antiserotonergic activities in rat aorta

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 3, 2002, Pages 198-204

  Indra, Bachtiar ^a   Matsunaga, Kimihiro ^a   Hoshino, Osamu ^a   Suzuki, Masaji ^a   Ogasawara, Hiromichi ^a   Ishiguro, Masaji ^a   Ohizumi, Yasushi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

( ) nantenine derivative; Antiserotonergic activity; Molecular modeling; SAR

Indexed keywords

4ALPHA HYDROXYNANTENINE; 4BETA HYDROXYNANTENINE; ASPARTIC ACID; DOMESTICINE; DRUG DERIVATIVE; ETHYLNORNANTENINE; HYDROXYL GROUP; METHYL GROUP; N TRIFLUOROACETYLNORDOMESTICINE; N TRIFLUOROACETYLNORNANTENINE; NANTENINE; NITROGEN; NORDOMESTICINE; NORNANTENINE; OXYGEN; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY TONE; ARTICLE; BINDING AFFINITY; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGEN BOND; MALE; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SEROTONINERGIC SYSTEM; STRUCTURE ACTIVITY RELATION; THORACIC AORTA;

ANIMALS; AORTA, THORACIC; APORPHINES; FRONTAL LOBE; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036202852     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-019     Document Type: Article

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