Depressed expression of adipocyte β-adrenergic receptors is a common feature of congenital and diet-induced obesity in rodents

International Journal of Obesity

Volumn 23, Issue 7, 1999, Pages 669-677

  Collins, S ^a   Daniel, K W ^a   Rohlfs, E M ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adipose tissue; Messenger RNA (or mRNA); Obesity

Indexed keywords

BETA ADRENERGIC RECEPTOR; CARBOXYPEPTIDASE; MESSENGER RNA; RECEPTOR SUBTYPE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DIABETES MELLITUS; DIET; ENDOCRINE FUNCTION; GENE EXPRESSION; MOUSE; NONHUMAN; NORTHERN BLOTTING; OBESITY; PRIORITY JOURNAL; WHITE ADIPOSE TISSUE;

EID: 0033066802     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800894     Document Type: Article

References (44)

1. 1 Marshall NB, Engel FL. The influence of epinephrine and fasting on adipose tissue content and release of free fatty acids in obese-hyperglycemic and lean mice. J Lipid Res 1960; 1: 339-342.
2. 2 Laudat MH, Pairault J. An impaired response of adenylate cyclase to stimulation by epinephrine in adipocyte plasma membranes from genetically obese mice (ob/ob). Eur J Biochem 1975; 56: 583-589.
3. 3 Shepherd RE, Malbon CC, Smith CJ, Fain JN. Lipolysis and adenosine 3′:5′-monophosphate metabolism in isolated white fat cells from genetically obese-hyperglycemic mice (ob/ob). J Biol Chem 1977; 252: 7243-7248.
4. 4 Bray GA. The Zucker-fatty rat: a review. Fed Proc 1977; 36: 148-153.
5. 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. Mol Endocrinol 1994; 8: 518-527.
6. 6 Coleman DL. Diabetes-obesity syndromes in mice. Diabetes 1982; 31: 1-6.
7. 7 Coleman DL, Eicher EM. Fat (fat) and tubby (tub): two autosomal recessive mutation causing obesity syndromes in the mouse. J Hered 1990; 81: 424-427.
8. 8 Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-479.
9. 9 Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995; 83: 1263-1271.
10. 10 Lee G-H, Proenca R, Montez, J. M, Carroll, K. M, Darbishzadeh, J. G, Lee, J. I, and Friedman, J. M. Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996; 379: 632-635.
11. 11 Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng Z, Ellis SJ, Lakery ND, Culpepper J, Moore KJ, Breitbart TE, Duyk GM, Tepper RI, Morgenstern JP. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996; 84: 491-495.
12. 12 Naggert JK, Fricker LD, Varlamov O, Nishina PM, Rouille Y, Steiner DF, Carroll RJ, Paigen BJ, Leiter EH. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity. Nat Genet 1995; 10: 135-142.
13. 13 Noben-Trauth K, Naggert JK, North MA, Nishina PM. A candidate gene for the mouse mutation tubby. Nature 1996; 380: 534-53-8.
14. 14 Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 1988; 37: 1163-1167.
15. 15 Surwit RS, Feinglos MN, Rodin J, Sutherland A, Petro AE, Opara EC, Huhn CM, Rebuffe-Scrive M. Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 1995; 44: 645-651.
16. 3-adrenergic receptor agonist treatment of diet-induced obesity in mice. Endocrinology 1997; 138: 405-413.
17. 17 Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294-5299.
18. 3-adrenergic receptor subtypes in immortalized brown adipose cell lines. J Biol Chem 1995; 270: 10723-10732.
19. 19 Hummel KP, Dickie MM, Coleman DL. Diabetes, a new mutation in the mouse. Science 1966; 153: 1127-1128.
20. 20 Thurlby PL, Trayhurn P. The development of obesity in preweaning ob/ob mice. Br J Nutr 1978; 39: 397-402.
21. 21 Trayhurn P, James WPT. Thermoregulation and non-shivering thermogenesis in the genetically obese (ob/ob) mouse. Pfluegers Arch Eur J Physiol 1978; 373: 189-193.
22. 22 Hummel KP, Coleman DL, Lane PW. The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains. Biochem Genet 1972; 7: 1-13.
23. 23 Naggert JK, Mu JL, Frankel W, Bailey DW, Paigen B. Genomic analysis of the C57BL/Ks mouse strain. Mammalian Genome 1995; 6: 131-133.
24. 3-adrenergic receptor. Science 1989; 245: 1118-1121.
25. 25 Muzzin P, Revelli JP, Kuhne F, Gocayne JD, McCombie WR, Venter JC, Giacobino J-P, Fraser CM. An adipose tissue-specific β-adrenergic receptor. Molecular cloning and down-regulation in obesity. J Biol Chem 1991; 266: 24053-24058.
26. 26 Mory G, Bouillaud F, Combes-George M, Ricquier D. Noradrenaline controls the concentration of the uncoupling protein in brown adipose tissue. FEBS Lett 1984; 166: 393-396.
27. 27 Bouillaud F, Ricquier D, Mory G, Thibault J. Increased level of mRNA for the uncoupling protein in brown adipose tissue of rats during thermogenesis induced by cold exposure or norepinephrine infusion. J Biol Chem 1984; 259: 11583-11586.
28. 28 Bray GA, York DA, Fisler JS. Experimental obesity: a homeostatic failure due to defective nutrient stimulation of the sympathetic nervous system. Vitam Horm 1989; 45: 1-125.
29. 29 Holt SJ, York DA. Studies on the sympathetic efferent nerves of brown adipose tissue of lean and obese Zucker rats. Brain Res 1989; 481: 106-112.
30. 30 Levin BE, Triscari J, Sullivan AC. Altered sympathetic activity during development of diet-induced obesity in rats. Am J Physiol 1983; 244: R347-R371.
31. 31 Levin BE, Triscari J, Sullivan AC. Relationship between sympathetic activity and diet-induced obesity in two rat Strains. Am J Physiol 1983; 245: R364-R371.
32. 32 Mercer SW, Trayhurn P. Effect of high fat diets on energy balance and thermogenesis in brown adipose tissue of lean and genetically obese ob/ob mice. J Nutr 1987; 117: 2147-2153.
33. 33 Kuhn C, Surwit RS, Feinglos M. Glipizide stimulates sympathetic outflow in diabetes-prone mice. Life Sci 1995; 56: 661-666.
34. 34 Stiles G, Caron M, Lefkowitz R. β-adrenergic receptors: biochemical mechanisms of physiological regulation. Physiol Rev 1984; 64: 661-742.
35. 3-adrenoceptor messenger ribonucleic acids in adipose tissues. Endocrinology 1992; 130: 109-114.
36. 3-adrenoceptor gene expression in brown-fat cells is transient and recovery is dependent upon a short-lived protein factor. J Biol Chem 1996; 271: 33366-33375.
37. 37 Herberg L, Coleman DL. Laboratory animals exhibiting obesity and diabetes syndromes. Metabolism 1977; 26: 59-99.
38. 3-adrenergic receptor responsiveness in 3T3-F442A adipocytes. J Biol Chem 1992; 267: 15909-15915.
39. 2-Adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. J Biol Chem 1988; 263: 9067-9070.
40. 40 Solomon J, Mayer J. The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob/ob mice. Endocrinology 1973; 93: 510-513.
41. 41 Bray GA, Stern JS, Castonguay TW. Effect of adrenalectomy and high-fat diet on the fatty Zucker rat. Am J Physiol 1992; 262: E32-E39.
42. 42 Langley SC, York DA. Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats. Am J Physiol 1990; 259: R539-R544.
43. 43 Gettys TW, Watson PM, Taylor IL, Collins S. RU-486 (Mifepristone ameliorates diabetes but does not correct deficient β-adrenergic signalling in adipocytes from mature C57BL/6J-ob/ob mice. Int J Obes 1997; 21: 865-873.
44. 3-adrenergic receptor expression in white adipocytes from C57BL/6J-ob/ob mice. Endocrinology 1997; 138: 2697-2704.