Effects of cyclooxygenase-2 inhibitor on glucagon-induced delayed gastric emptying and gastric dysrhythmia in dogs

Neurogastroenterology and Motility

Volumn 19, Issue 2, 2007, Pages 144-151

  Xu, J ^b   Chen, J D Z ^a,b  

^a GI Research   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cyclooxygenase 2 inhibitor; Gastric emptying; Gastric slow waves; Gastrointestinal motility; Glucagon

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GLUCAGON; GLUCOSE; PHENOLSULFONPHTHALEIN; PROSTAGLANDIN;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL MONITORING; CALCULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DUODENUM FISTULA; DUODENUM INTUBATION; EXPERIMENTAL DOG; FEEDING; FEMALE; FLUID INTAKE; GASTRIC DYSMOTILITY; GLUCOSE BLOOD LEVEL; JEJUNUM; MEAL; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; SEROSA; STATISTICAL SIGNIFICANCE; STOMACH EMPTYING; STOMACH PARESIS;

ANIMALS; BLOOD GLUCOSE; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; DOGS; FEMALE; GASTRIC EMPTYING; GASTROINTESTINAL MOTILITY; GASTROPARESIS; GLUCAGON; PYLORIC ANTRUM; PYRAZOLES; SULFONAMIDES;

EID: 33846346584     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2006.00887.x     Document Type: Article

References (37)

1. Folwaczny C, Wawarta R, Otto B, Friedrich S, Landgrave R, Riepl RL. Gastric emptying of solid and liquid meals in healthy controls compared with long-term type-1 diabetes mellitus under optimal glucose control. Exp Clin Endocrinol Diabetes 2003; 111: 223-9.
2. Anitha M, Gondha C, Sutliff R et al. GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway. J Clin Invest 2006; 116: 344-56.
3. Schvarcz E, Palmer M, Aman J, Horowitz M, Stridsberg M, Berne C. Physiological hyperglycemia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus. Gastroenterology 1997; 113: 60-6.
4. Hasler WL, Soudah HC, Dulai G, Owyang C. Mediation of hyperglycemia-evoked gastric slow-wave dysrhythmia by endogenous prostaglandins. Gastroenterology 1995; 108: 727-36.
5. Hebbard GS, Sun WM, Dent J, Horowitz M. Hyperglycemia affects proximal gastric motor and sensory function in normal subjects. Eur J Gastroenterol Hepatol 1996; 8: 211-7.
6. Coleski R, Gonlachanvit S, Owyang C, Hasler WL. Selective reversal of hyperglycemia-evoked gastric myoelectric dysrhythmias by nitregic stimulation in healthy humans. J Pharmacol Exp Ther 2005; 312: 103-11.
7. Stein J, Zeuzem S, Uphoff K, Laube H. Effects of prostaglandins and indomethacin on gastric emptying in the rat. Prostaglandins 1994; 47: 31-40.
8. Kim CH, Zinsmeister AR, Malagelada JR. Mechanisms of canine gastric dysrhythmia. Gastroenterology 1987; 92: 993-9.
9. Costa M. COX and the gut: now we see it now we don't. Neurogastroenterol Motil 2004; 16: 693-5.
10. Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Annu Rev Pharmacol 1998; 38: 97-120.
11. Jeandidier N, Boullu-Sanchis S. Hyperglycemia and acute illness. Ann Endocrinol 2006; 67: 224-32.
12. Porcher C, Horowitz B, Bayguinov O, Ward SM, Sanders KM. Constitutive expression and function of cyclooxygenase-2 in murine gastric muscles. Gastroenterology 2002; 122: 1442-54.
13. Feldman M, McMahon AT. Do cycloogenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointestinal toxicity? Ann Intern Med 2000; 132: 134-43.
14. Frank JW, Saslow SB, Camilleri M, Thomforde GM, Dinneen S, Rizza RA. Mechanismof accelerated gastric emptying of liquids and hyperglycemia in patients with type II diabetes mellitus. Gastroenterology 1995; 109: 755-65.
15. Jonderko G, Jonderko G, Golab T. Effect of glucagons on gastric emptying and on postprandial gastrin and insulin release in man. Mater Med Pol 1989; 21: 92-6.
16. Xu XH, Qian LW, Chen JDZ. Anti-dysrhythmia effects of long-pulse gastric electrical stimulation in dogs. Digestion 2004; 69: 63-70.
17. Shibata C, Naito H, Jin XL et al. Effects of glucagons, glicentin, glucagons-like peptide-1 and -2 on the interdigestive gastroduodenal motility in dogs with a vagally denervated gastric pouch. Scand J Gastroenterol 2001; 36: 1049-55.
18. Kawamoto H, Yamamura H, Tatsuta M, Okuda S. Effects of glucagons on gastric motility examined by the acetaminophen absorption method and the endoscopic procedure. Arzneimittelforschung 1985; 35: 1475-7.
19. Familoni BO, Abell TL, Voeller G, Salem A, Gaber O. Electrical stimulation at a frequency higher than basal rate in human stomach. Dig Dis Sci 1997; 42: 885-91.
20. Bellahsene BE, Lind CD, Schirmer BD, Updike OL, McCallum RW. Acceleration of gastric emptying with electrical stimulation in a canine model of gastroparesis. Am J Physiol 1992; 262: G826-834.
21. Qian LW, Pasricha PJ, Chen JD. Origins and patterns of spontaneous and drug-induced canine gastric myoelectrical dysrhythmia. Dig Dis Sci 2003; 48: 508-15.
22. Paulson SK, Vaughn MB, Jessen SM et al. Pharmacokinetics of celecoxib after oral administration in dogs and humans: effect of food and site of absorption. J Pharmacol Exp Ther 2001; 297: 638-45.
23. Chen JDZ, McCallum RW. Electrogastrographic parameters and their clinical significance. In: Chen JDZ, McCallum RW, eds. The Electrogastrography: Principles and Clinical Applications. New York: Raven Press, 1994: 45-73.
24. Xu XH, Wang ZS, Hayes J, Chen JDZ. Is there a one-to-one correlation between gastric emptying of liquids and gastric myoelectrical or motor activity in dogs? Dig Dis Sci 2002; 47: 365-72.
25. Verne GN, Sninsky CA. Diabetes and the gastrointestinal tract. Gastroenterol Clin North Am 1998; 27: 861-74.
26. Spallone V. Glyceamic control and gastric emptying. Diabetes Nutr Metab 2004; 17: 47-55.
27. Warner TD, Mitchell JA. Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. FASEB J 2004; 18: 790-804.
28. Maedler K, Sergeev P, Ris F et al. Glucose-induced β-cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. J Clin Invest 2002; 110: 851-60.
29. Suto G, Kiraly A, Tache Y. Interleukin 1 beta inhibits gastric emptying in rats: mediation through prostaglandin and corticotropin-releasing factor. Gastroenterology 1994; 106: 1568-75.
30. Schvarcz E, Palmer M, Aman J, Horowitz M, Stridsberg M, Berne C. Physiological hyperglycemia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus. Gastroenterology 1997; 113: 60-6.
31. Calatayud S, Garcia-Zaragoza E, Hernandez C et al. Downregulation of nNOS and synthesis of PGs associated with endotoxin-induced delay in gastric emptying Am J Physiol 2002; 283: G1360-7.
32. Jeandidier N, Boullu-Sanchis S. Hyperglycemia and acute illness. Ann Endocrinol 2006; 67: 224-32.
33. Persaud SJ, Burns CJ, Belin VD, Jones PM. Glucose-induced regulation of COX-2 expression in human islets of Langerhans. Diabetes 2004; 53: S190-2.
34. Bouras EP, Burton DD, Camilleri M, Stephen DA, Thomforde GM. Effect of cyclooxygenase-2 inhibitors on gastric emptying and small intestinal transit in human. Neurogastroenterol Motil 2004; 16: 729-35.
35. Zhang J, Chen JD. Pacing the gut in motility disorders. Curr Treat Options Gastroenterol 2006; 9: 351-60.
36. Watanabe O, Atobe Y, Akagi M, Nishi K. Effects of glucagon on myoelectrical activity of the stomach of conscious and anesthetized dogs. Eur J Pharmacol 1982 8; 31-41.
37. Santamaria L, de Miguel E, Codesal J, Ramirez JR, Picazo J. Identification of glucagon binding sites on smooth muscle tissue of dog intestine. Quantification by means of ultrastructural autoradiography. Anat Anz 1991; 172: 149-57.