-
1
-
-
0027753736
-
Xenopus peroxisome proliferator activated receptors: Genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids
-
Krey G, Keller H, Mahfoudi A, et al. Xenopus peroxisome proliferator activated receptors: genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids. J Steroid Biochem Mol Biol 1993;47: 65-73.
-
(1993)
J Steroid Biochem Mol Biol
, vol.47
, pp. 65-73
-
-
Krey, G.1
Keller, H.2
Mahfoudi, A.3
-
2
-
-
0029102676
-
Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPARγ) gene: Alternative promoter use and different splicing yield two mPPARγ isoforms
-
Zhu Y, Qi C, Korenberg JR, et al. Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPARγ) gene: alternative promoter use and different splicing yield two mPPARγ isoforms. Proc Natl Acad Sci U S A 1995;92:7921-5.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7921-7925
-
-
Zhu, Y.1
Qi, C.2
Korenberg, J.R.3
-
3
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
-
Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992;358:771-4.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
-
4
-
-
0028202490
-
Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival
-
Chawla A, Lazar MA. Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival. Proc Natl Acad Sci U S A 1994;91:1786-90.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 1786-1790
-
-
Chawla, A.1
Lazar, M.A.2
-
5
-
-
0028180070
-
mPPARγ: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM. mPPARγ: tissue-specific regulator of an adipocyte enhancer. Genes 1994;8:1224-34.
-
(1994)
Genes
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
6
-
-
0031898610
-
-
Spiegelman BM. PPAR-γ: adipogenic regulator and thiazolidinedione receptor. Diabetes 1998;47:507-14.
-
Spiegelman BM. PPAR-γ: adipogenic regulator and thiazolidinedione receptor. Diabetes 1998;47:507-14.
-
-
-
-
7
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPAR γ
-
Mueller E, Sarraf P, Tontonoz P, et al. Terminal differentiation of human breast cancer through PPAR γ. Mol Cell 1998;1:465-70.
-
(1998)
Mol Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
-
8
-
-
0033227254
-
Peroxisome proliferator-activated receptor γ activation in human breast cancer
-
Yee LD, Sabourin CLK, Li L, et al. Peroxisome proliferator-activated receptor γ activation in human breast cancer. Int J Oncol 1999;15:967-73.
-
(1999)
Int J Oncol
, vol.15
, pp. 967-973
-
-
Yee, L.D.1
Sabourin, C.L.K.2
Li, L.3
-
9
-
-
0037361266
-
The antiproliferative effects of PPARγ ligands in normal human mammary epithelial cells
-
Yee LD, Guo Y, Bradbury J, Suster S, Clinton SK, Seewaldt VL. The antiproliferative effects of PPARγ ligands in normal human mammary epithelial cells. Breast Cancer Res Treat 2003;78:179-92.
-
(2003)
Breast Cancer Res Treat
, vol.78
, pp. 179-192
-
-
Yee, L.D.1
Guo, Y.2
Bradbury, J.3
Suster, S.4
Clinton, S.K.5
Seewaldt, V.L.6
-
10
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
Elstner E, Muller C, Koshizuka K, et al. Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 1998;95:8806-11.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
-
11
-
-
0033571433
-
A new ligand for the peroxisome proliferator-activated receptor-γ (PPAR-γ), GW7845, inhibits rat mammary carcinogenesis
-
Suh N, Wang Y, Williams CR, et al. A new ligand for the peroxisome proliferator-activated receptor-γ (PPAR-γ), GW7845, inhibits rat mammary carcinogenesis. Cancer Res 1999;59:5671-3.
-
(1999)
Cancer Res
, vol.59
, pp. 5671-5673
-
-
Suh, N.1
Wang, Y.2
Williams, C.R.3
-
12
-
-
4143150044
-
PPARγ influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis
-
Nicol CJ, Yoon M, Ward JM, et al. PPARγ influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis. Carcinogenesis 2004;25: 1747-55.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1747-1755
-
-
Nicol, C.J.1
Yoon, M.2
Ward, J.M.3
-
13
-
-
0033625429
-
Over-representation of PPAR sequence variants in sporadic cases of glioblastoma multiforme: Preliminary evidence for common low penetrance modifiers for brain tumour risk in the general population
-
Zhou X-P, Smith WM, Gimm O, et al. Over-representation of PPAR sequence variants in sporadic cases of glioblastoma multiforme: preliminary evidence for common low penetrance modifiers for brain tumour risk in the general population. J Med Genet 2000;37: 410-4.
-
(2000)
J Med Genet
, vol.37
, pp. 410-414
-
-
Zhou, X.-P.1
Smith, W.M.2
Gimm, O.3
-
15
-
-
0034456568
-
Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans
-
Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000;85:2402-10.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2402-2410
-
-
Katz, A.1
Nambi, S.S.2
Mather, K.3
-
16
-
-
0035873953
-
Tumor suppressor and anti-inflammatory actions of PPAR (agonists are mediated via upregulation of PTEN
-
Patel L, Pass I, Coxon P, Downes CP, Smith SA, Macphee CH. Tumor suppressor and anti-inflammatory actions of PPAR (agonists are mediated via upregulation of PTEN. Curr Biol 2001;11:764-8.
-
(2001)
Curr Biol
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
17
-
-
0035990751
-
Novel therapeutic approach: Ligands for PPARγ and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells
-
Elstner E, Williamson EA, Zang C, et al. Novel therapeutic approach: ligands for PPARγ and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells. Breast Cancer Res Treat 2002;74: 155-65.
-
(2002)
Breast Cancer Res Treat
, vol.74
, pp. 155-165
-
-
Elstner, E.1
Williamson, E.A.2
Zang, C.3
-
19
-
-
0042524273
-
Expression of peroxisome- proliferator activated receptor γ (PPARγ) and the PPARγ co-activator, PGC-1, in human breast cancer correlates with clinical outcomes
-
Jiang WG, Douglas-Jones A, Mansel RE. Expression of peroxisome- proliferator activated receptor γ (PPARγ) and the PPARγ co-activator, PGC-1, in human breast cancer correlates with clinical outcomes. Int J Cancer 2003;106:752-7.
-
(2003)
Int J Cancer
, vol.106
, pp. 752-757
-
-
Jiang, W.G.1
Douglas-Jones, A.2
Mansel, R.E.3
-
20
-
-
18144388677
-
Selective activation of PPARγ in breast, colon, and lung cancer cell lines
-
Allred CD, Kilgore MW. Selective activation of PPARγ in breast, colon, and lung cancer cell lines. Mol Cell Endocrinol 2005;235:21-9.
-
(2005)
Mol Cell Endocrinol
, vol.235
, pp. 21-29
-
-
Allred, C.D.1
Kilgore, M.W.2
-
21
-
-
4944228674
-
Haploid inactivation of the Amplified-in-Breast Cancer 3 coactivator reduces the inhibitory effect of peroxisome proliferator-activated receptor γ and retinoid X receptor on cell proliferation and accelerates polyoma middle-T antigen-induced mammary tumorigenesis in mice
-
Zhang H, Kuang S-Q, Liao L, Zhou S, Xu J. Haploid inactivation of the Amplified-in-Breast Cancer 3 coactivator reduces the inhibitory effect of peroxisome proliferator-activated receptor γ and retinoid X receptor on cell proliferation and accelerates polyoma middle-T antigen-induced mammary tumorigenesis in mice. Cancer Res 2004;64: 7169-77.
-
(2004)
Cancer Res
, vol.64
, pp. 7169-7177
-
-
Zhang, H.1
Kuang, S.-Q.2
Liao, L.3
Zhou, S.4
Xu, J.5
-
22
-
-
33646434260
-
Increased PTEN expression due to transcriptional activation of PPARγ by Lovastatin and Rosiglitazone
-
Teresi RE, Shaiu C-W, Chen C-S, Chatterjee VK, Waite KA, Eng C. Increased PTEN expression due to transcriptional activation of PPARγ by Lovastatin and Rosiglitazone. Int J Cancer 2006;118:2390-8.
-
(2006)
Int J Cancer
, vol.118
, pp. 2390-2398
-
-
Teresi, R.E.1
Shaiu, C.-W.2
Chen, C.-S.3
Chatterjee, V.K.4
Waite, K.A.5
Eng, C.6
-
23
-
-
0029067225
-
Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
-
Keller H, Givel F, Perroud M, Wahli W. Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol 1995;9:794-804.
-
(1995)
Mol Endocrinol
, vol.9
, pp. 794-804
-
-
Keller, H.1
Givel, F.2
Perroud, M.3
Wahli, W.4
-
24
-
-
24344455975
-
Estrogen receptor a binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor γ signaling in breast cancer cells
-
Bonofiglio D, Gabriele S, Aquila S, et al. Estrogen receptor a binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor γ signaling in breast cancer cells. Clin Cancer Res 2005;11: 6139-47.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6139-6147
-
-
Bonofiglio, D.1
Gabriele, S.2
Aquila, S.3
-
25
-
-
0034674567
-
Degradation of the peroxisome proliferator-activated receptor γ is linked to ligand-dependent activation
-
Hauser S, Adelmant G, Sarraf P, Wright HM, Mueller E, Spiegelman BM. Degradation of the peroxisome proliferator-activated receptor γ is linked to ligand-dependent activation. J Biol Chem 2000;275: 18527-33.
-
(2000)
J Biol Chem
, vol.275
, pp. 18527-18533
-
-
Hauser, S.1
Adelmant, G.2
Sarraf, P.3
Wright, H.M.4
Mueller, E.5
Spiegelman, B.M.6
-
26
-
-
0037356826
-
The role of the novel adipocyte-derived hormone adiponectin in human disease
-
Diez JJ, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur J Endocrinol 2003;148:293-300.
-
(2003)
Eur J Endocrinol
, vol.148
, pp. 293-300
-
-
Diez, J.J.1
Iglesias, P.2
-
27
-
-
0028787490
-
A novel serum protein similar to C1q, produced exclusively in adipocytes
-
Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270:26746-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 26746-26749
-
-
Scherer, P.E.1
Williams, S.2
Fogliano, M.3
Baldini, G.4
Lodish, H.F.5
-
28
-
-
4243645912
-
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARγ agonists: A potential mechanism of insulin sensitization
-
Combs TP, Wagner JA, Berger J, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARγ agonists: a potential mechanism of insulin sensitization. Endocrinology 2002;143: 998-1007.
-
(2002)
Endocrinology
, vol.143
, pp. 998-1007
-
-
Combs, T.P.1
Wagner, J.A.2
Berger, J.3
-
30
-
-
1442354888
-
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
-
Brakenhielm E, Veitonmaki N, Cao R, et al. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A 2004;101: 2476-81.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2476-2481
-
-
Brakenhielm, E.1
Veitonmaki, N.2
Cao, R.3
-
31
-
-
0036270579
-
Upper abdominal obesity, insulin resistance and breast cancer risk
-
Stoll BA. Upper abdominal obesity, insulin resistance and breast cancer risk. Int J Obes Relat Metab Disord 2002;26:747-53.
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 747-753
-
-
Stoll, B.A.1
-
32
-
-
0033152206
-
Loss-of-function mutations in PPARγ associated with human colon cancer
-
Sarraf P, Mueller E, Smith WM, et al. Loss-of-function mutations in PPARγ associated with human colon cancer. Mol Cell 1999;3:799-804.
-
(1999)
Mol Cell
, vol.3
, pp. 799-804
-
-
Sarraf, P.1
Mueller, E.2
Smith, W.M.3
-
33
-
-
0035394518
-
Mutational analysis of the peroxisome proliferator-activated receptorg gene in human malignancies
-
Ikezoe T, Miller CW, Kawano S, et al. Mutational analysis of the peroxisome proliferator-activated receptorg gene in human malignancies. Cancer Res 2001;61:5307-10.
-
(2001)
Cancer Res
, vol.61
, pp. 5307-5310
-
-
Ikezoe, T.1
Miller, C.W.2
Kawano, S.3
-
34
-
-
21144442203
-
The PPARγ K422Q mutation does not contribute to troglitazone inefficiency in colon cancer treatment
-
Bouancheau D, Buecher B. The PPARγ K422Q mutation does not contribute to troglitazone inefficiency in colon cancer treatment. Cancer Lett 2005;224:111-6.
-
(2005)
Cancer Lett
, vol.224
, pp. 111-116
-
-
Bouancheau, D.1
Buecher, B.2
-
35
-
-
0031595923
-
A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, et al. A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 1998;20:284-7.
-
(1998)
Nat Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
-
36
-
-
0345306138
-
Interaction between a peroxisome proliferator-activated receptor γ gene polymorphism and dietary intake in relation to body mass
-
Memisoglu A, Hu FB, Hankinson SE, et al. Interaction between a peroxisome proliferator-activated receptor γ gene polymorphism and dietary intake in relation to body mass. Hum Mol Genet 2003;12: 2923-9
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2923-2929
-
-
Memisoglu, A.1
Hu, F.B.2
Hankinson, S.E.3
-
37
-
-
0033616795
-
Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma
-
Demetri GD, Fletcher CDM, Mueller E, et al. Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma. Proc Natl Acad Sci U S A 1999;96:3951-6.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3951-3956
-
-
Demetri, G.D.1
Fletcher, C.D.M.2
Mueller, E.3
-
38
-
-
0343855442
-
Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer
-
Mueller E, Smith M, Sarraf P, et al. Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer. Proc Natl Acad Sci U S A 2000;97:10990-5.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10990-10995
-
-
Mueller, E.1
Smith, M.2
Sarraf, P.3
-
39
-
-
4844219655
-
Rosiglitazone versus placebo for men with prostate carcinoma and a risng serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy
-
Smith MR, Manola J, Kaufman DS, et al. Rosiglitazone versus placebo for men with prostate carcinoma and a risng serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy. Cancer 2004;101:1569-74.
-
(2004)
Cancer
, vol.101
, pp. 1569-1574
-
-
Smith, M.R.1
Manola, J.2
Kaufman, D.S.3
-
40
-
-
0036730017
-
A phase II study of troglitazone, an activator of the PPARγ receptor, in patients with chemotherapy-resistant metastatic colorectal cancer
-
Kulke MH, Demetri GD, Sharpless NE, et al. A phase II study of troglitazone, an activator of the PPARγ receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J 2002;8:395-9.
-
(2002)
Cancer J
, vol.8
, pp. 395-399
-
-
Kulke, M.H.1
Demetri, G.D.2
Sharpless, N.E.3
-
41
-
-
0037899628
-
Use of the peroxisome proliferator-activated receptor (PPAR) γ ligand troglitazone as treatment for refractory breast cancer: A phase II study
-
Burstein HJ, Demetri GD, Mueller E, Sarraf P, Spiegelman BM, Winer EP. Use of the peroxisome proliferator-activated receptor (PPAR) γ ligand troglitazone as treatment for refractory breast cancer: a phase II study. Breast Cancer Res Treat 2003;79: 391-7.
-
(2003)
Breast Cancer Res Treat
, vol.79
, pp. 391-397
-
-
Burstein, H.J.1
Demetri, G.D.2
Mueller, E.3
Sarraf, P.4
Spiegelman, B.M.5
Winer, E.P.6
|